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The map label for this gene is ubiB [C]

Identifier: 34498422

GI number: 34498422

Start: 3245393

End: 3247075

Strand: Direct

Name: ubiB [C]

Synonym: CV_2967

Alternate gene names: 34498422

Gene position: 3245393-3247075 (Clockwise)

Preceding gene: 34498413

Following gene: 34498423

Centisome position: 68.31

GC content: 64.88

Gene sequence:

>1683_bases
ATGATTCGGGAAACCTTGATTGCAATGCGGGACTTACCGCGGTTAAGAGAAATCAGCGGAATTTTGATCCGTCATGGACT
GGGAGAGTTCGCCCAGCGGCTGAAATTGCCGCGCGCGATGGAAAAGGCCGGGGAGTGGCTGAACCTGTCGCTGCCGGAGG
GCGAGTCCGGGCGGCCGACCGCGGTGCGGGTGAGGCTGGCCTTCGAGGAGCTGGGGCCCACCTTCATCAAGCTGGGCCAG
ATCCTGTCCACCCGGGTGGACGTGTTTCCGCCGGACTGGATAGACGAGTTCGAAAAGCTGCAGAACCGGGTGCCGCCGCT
GCCGCCGGCGATGGTTCGAAAGATGATAGTCGATACGCTGGGCGCCGAGGCCGACCAGTTGTTCGCCGAGTTCGACATGC
AGCCGATAGGCTCGGCCTCCATCGCCCAGGTGCATCGCGCCAGGTTGAAGGATGGCCGCGAGGTGGCGGTGAAGCTGCGT
CGGCCGGGCATCGCCGACAAGGTGGAGGCCGATCTGCGCATCCTCGCCCACCTCGCCCACCTGCTGGAGCTGGAGTTCCC
CGAACTGCGGCGCTACCAGCCGTCCGGCATCGCCGCGCAGTTCGCGCGCTCGTTGCGCCGCGAGCTGGACCTGGCCATCG
AGGCGCGCAATATGGAGCGTTTCGCCAAGGACTTCGTCGACGACCCCTTCGTCATGGTGCCGCAAGTGCATTGGGAGTAC
ACCAACGCCGCCGTCAATGTGCAGACCTTCGTCGACGGCGTGCCGGCCAGCGATCTGTCGCGGCTGAAGGACAGCGGCCT
GGATCCGGTGCTGTTGGCCCAGCGCGGCGCGGACGCGGTGCTGAAGATGATACTGATCAACGGCTTCTTCCATGCCGACC
CCCACCCCGGCAACGTGTTCTTCCTGGCCGAGCACCGCATCGCCTTCATCGATTTTGGCATGGTGGGGCGCATCAGTCAC
GCGCGGCGCGACGAGATCGTCGATCTGCTGTCGGCGGTGGCCGAGCGCAACGAGCACGGCATCATCGACGTGCTGGTCGA
ATGGACCGGCAGCGCGCCGGTGGACATGCAGAAATTCGCCGACGAGGTCGGCGAGTTCATGTTCCAGTACGAGCACCTGC
CGCTGAAGGGGCTGAACATCAGCCAGCTGATCTCCGACATCATGGCGCTGATCCGCAACCACGGCATCGTGCTGCCGCCG
GACATGGCCATGCTGTTCAAGGCGCTGGTGACGCTGGAGGGCCTGGGGCGGCAGCTGAACCCCGATTTCCAGCTGGTCGC
CCACATCACCCCCTTCGTCAAGGAGCTGATCGTCGCCCGCTACCACCCGGCGGCGCTGCTCAAGCGCGGGCGGCAGACGC
TGTCAGAGGGGCTGGAGATGATCACCGGCCTGCCGCGCGACTTGGTCCGCATCGGCCGCGACATGCGCCACGGCAAGTTC
CGCGTCAACCTCGACCTGCAGCGGCTGGACAGCTTCGGCAAGCAGCTGGACCGCAGCAGCAACCGGCTGACCATGGGCAT
CGTCACCGGCTGCCTGATCATAGGCTCGTCCATCGTGATGACGGTGAACGCCGGACCCAAGCTGTTCGGCCTGCCCTTCT
TCGGCTTCTTCGGCTTCATGCTGGCGCTGTTCAACAGCGTGTGGCTGGTCTGGTCGATCTGGCGCTCAGGCAAGGACTTA
TAA

Upstream 100 bases:

>100_bases
CCGCCAGCGCCAACGCTGATAAGCGGAGTTGCAATTTCATAGGCCGCACTCTATCGGACGGGGCCGGTAGTGTAAAGCCA
AGCGGGACGGCGAAAAGCAC

Downstream 100 bases:

>100_bases
CTGTCCGGGCAGGCTTTGGAACCATTGGCGATACGGAATACCGCGGCATCAAGTCGGGCGGAGGCGGGTCGATAGCGAGG
AAGTACATCTTGAGGGACGC

Product: ubiquinone biosynthesis protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MIRETLIAMRDLPRLREISGILIRHGLGEFAQRLKLPRAMEKAGEWLNLSLPEGESGRPTAVRVRLAFEELGPTFIKLGQ
ILSTRVDVFPPDWIDEFEKLQNRVPPLPPAMVRKMIVDTLGAEADQLFAEFDMQPIGSASIAQVHRARLKDGREVAVKLR
RPGIADKVEADLRILAHLAHLLELEFPELRRYQPSGIAAQFARSLRRELDLAIEARNMERFAKDFVDDPFVMVPQVHWEY
TNAAVNVQTFVDGVPASDLSRLKDSGLDPVLLAQRGADAVLKMILINGFFHADPHPGNVFFLAEHRIAFIDFGMVGRISH
ARRDEIVDLLSAVAERNEHGIIDVLVEWTGSAPVDMQKFADEVGEFMFQYEHLPLKGLNISQLISDIMALIRNHGIVLPP
DMAMLFKALVTLEGLGRQLNPDFQLVAHITPFVKELIVARYHPAALLKRGRQTLSEGLEMITGLPRDLVRIGRDMRHGKF
RVNLDLQRLDSFGKQLDRSSNRLTMGIVTGCLIIGSSIVMTVNAGPKLFGLPFFGFFGFMLALFNSVWLVWSIWRSGKDL

Sequences:

>Translated_560_residues
MIRETLIAMRDLPRLREISGILIRHGLGEFAQRLKLPRAMEKAGEWLNLSLPEGESGRPTAVRVRLAFEELGPTFIKLGQ
ILSTRVDVFPPDWIDEFEKLQNRVPPLPPAMVRKMIVDTLGAEADQLFAEFDMQPIGSASIAQVHRARLKDGREVAVKLR
RPGIADKVEADLRILAHLAHLLELEFPELRRYQPSGIAAQFARSLRRELDLAIEARNMERFAKDFVDDPFVMVPQVHWEY
TNAAVNVQTFVDGVPASDLSRLKDSGLDPVLLAQRGADAVLKMILINGFFHADPHPGNVFFLAEHRIAFIDFGMVGRISH
ARRDEIVDLLSAVAERNEHGIIDVLVEWTGSAPVDMQKFADEVGEFMFQYEHLPLKGLNISQLISDIMALIRNHGIVLPP
DMAMLFKALVTLEGLGRQLNPDFQLVAHITPFVKELIVARYHPAALLKRGRQTLSEGLEMITGLPRDLVRIGRDMRHGKF
RVNLDLQRLDSFGKQLDRSSNRLTMGIVTGCLIIGSSIVMTVNAGPKLFGLPFFGFFGFMLALFNSVWLVWSIWRSGKDL
>Mature_560_residues
MIRETLIAMRDLPRLREISGILIRHGLGEFAQRLKLPRAMEKAGEWLNLSLPEGESGRPTAVRVRLAFEELGPTFIKLGQ
ILSTRVDVFPPDWIDEFEKLQNRVPPLPPAMVRKMIVDTLGAEADQLFAEFDMQPIGSASIAQVHRARLKDGREVAVKLR
RPGIADKVEADLRILAHLAHLLELEFPELRRYQPSGIAAQFARSLRRELDLAIEARNMERFAKDFVDDPFVMVPQVHWEY
TNAAVNVQTFVDGVPASDLSRLKDSGLDPVLLAQRGADAVLKMILINGFFHADPHPGNVFFLAEHRIAFIDFGMVGRISH
ARRDEIVDLLSAVAERNEHGIIDVLVEWTGSAPVDMQKFADEVGEFMFQYEHLPLKGLNISQLISDIMALIRNHGIVLPP
DMAMLFKALVTLEGLGRQLNPDFQLVAHITPFVKELIVARYHPAALLKRGRQTLSEGLEMITGLPRDLVRIGRDMRHGKF
RVNLDLQRLDSFGKQLDRSSNRLTMGIVTGCLIIGSSIVMTVNAGPKLFGLPFFGFFGFMLALFNSVWLVWSIWRSGKDL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=353, Percent_Identity=28.8951841359773, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI40254938, Length=227, Percent_Identity=33.0396475770925, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI217035081, Length=181, Percent_Identity=33.7016574585635, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI34147522, Length=427, Percent_Identity=25.2927400468384, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI32261307, Length=363, Percent_Identity=26.1707988980716, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI27363457, Length=383, Percent_Identity=23.4986945169713, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI217416386, Length=361, Percent_Identity=22.9916897506925, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI2367309, Length=524, Percent_Identity=28.4351145038168, Blast_Score=229, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17559152, Length=267, Percent_Identity=29.9625468164794, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17555620, Length=477, Percent_Identity=23.4800838574423, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI32565180, Length=435, Percent_Identity=26.4367816091954, Blast_Score=105, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6325148, Length=487, Percent_Identity=24.8459958932238, Blast_Score=130, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321319, Length=258, Percent_Identity=27.906976744186, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323282, Length=246, Percent_Identity=27.2357723577236, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24662575, Length=273, Percent_Identity=31.1355311355311, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI22024280, Length=263, Percent_Identity=28.1368821292776, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI18859849, Length=387, Percent_Identity=26.8733850129199, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63015; Mature: 63015

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRETLIAMRDLPRLREISGILIRHGLGEFAQRLKLPRAMEKAGEWLNLSLPEGESGRPT
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCCCCCC
AVRVRLAFEELGPTFIKLGQILSTRVDVFPPDWIDEFEKLQNRVPPLPPAMVRKMIVDTL
EEEEEEEHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GAEADQLFAEFDMQPIGSASIAQVHRARLKDGREVAVKLRRPGIADKVEADLRILAHLAH
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHEECCCCCHHHHHHHHHHHHHHHH
LLELEFPELRRYQPSGIAAQFARSLRRELDLAIEARNMERFAKDFVDDPFVMVPQVHWEY
HHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEE
TNAAVNVQTFVDGVPASDLSRLKDSGLDPVLLAQRGADAVLKMILINGFFHADPHPGNVF
CCCEEEHHHHHCCCCHHHHHHHHHCCCCCEEHHHCCHHHHHHHHHHHCCCCCCCCCCCEE
FLAEHRIAFIDFGMVGRISHARRDEIVDLLSAVAERNEHGIIDVLVEWTGSAPVDMQKFA
EEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHH
DEVGEFMFQYEHLPLKGLNISQLISDIMALIRNHGIVLPPDMAMLFKALVTLEGLGRQLN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
PDFQLVAHITPFVKELIVARYHPAALLKRGRQTLSEGLEMITGLPRDLVRIGRDMRHGKF
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCEE
RVNLDLQRLDSFGKQLDRSSNRLTMGIVTGCLIIGSSIVMTVNAGPKLFGLPFFGFFGFM
EEEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCEEEEECCCCCEECCHHHHHHHHH
LALFNSVWLVWSIWRSGKDL
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRETLIAMRDLPRLREISGILIRHGLGEFAQRLKLPRAMEKAGEWLNLSLPEGESGRPT
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCCCCCC
AVRVRLAFEELGPTFIKLGQILSTRVDVFPPDWIDEFEKLQNRVPPLPPAMVRKMIVDTL
EEEEEEEHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GAEADQLFAEFDMQPIGSASIAQVHRARLKDGREVAVKLRRPGIADKVEADLRILAHLAH
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHEECCCCCHHHHHHHHHHHHHHHH
LLELEFPELRRYQPSGIAAQFARSLRRELDLAIEARNMERFAKDFVDDPFVMVPQVHWEY
HHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEE
TNAAVNVQTFVDGVPASDLSRLKDSGLDPVLLAQRGADAVLKMILINGFFHADPHPGNVF
CCCEEEHHHHHCCCCHHHHHHHHHCCCCCEEHHHCCHHHHHHHHHHHCCCCCCCCCCCEE
FLAEHRIAFIDFGMVGRISHARRDEIVDLLSAVAERNEHGIIDVLVEWTGSAPVDMQKFA
EEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHH
DEVGEFMFQYEHLPLKGLNISQLISDIMALIRNHGIVLPPDMAMLFKALVTLEGLGRQLN
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCC
PDFQLVAHITPFVKELIVARYHPAALLKRGRQTLSEGLEMITGLPRDLVRIGRDMRHGKF
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHCCCEE
RVNLDLQRLDSFGKQLDRSSNRLTMGIVTGCLIIGSSIVMTVNAGPKLFGLPFFGFFGFM
EEEEEHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCEEEEECCCCCEECCHHHHHHHHH
LALFNSVWLVWSIWRSGKDL
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA