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The map label for this gene is dctR [H]

Identifier: 34498416

GI number: 34498416

Start: 3240405

End: 3241025

Strand: Reverse

Name: dctR [H]

Synonym: CV_2961

Alternate gene names: 34498416

Gene position: 3241025-3240405 (Counterclockwise)

Preceding gene: 34498417

Following gene: 34498415

Centisome position: 68.22

GC content: 68.12

Gene sequence:

>621_bases
ATGAGCGCGAAACGGCTGGCCATCATCGACGATGACGAGGCGGTGCGGCAGTCGCTGTTGTGGCTGCTGGACGGCCAGGG
TTACCGGGCCGACGGCTTCGACAGCGGCGAGGCCTTTCTGGCCGATGGCCATGGCGCCGAGTACAACGGCATCATTCTGG
ACCTGCGGCTGTCCGGCATCAGCGGCATCGTGCTGCTGGAAAAGCTGGCGCAGTGGCCGTACTGTCCGCCGGTGATCATG
CTGACCGCCCACGGCGACGTGCCGCACGCGGTGGCGGCGCTGAAGCTGGGCGCGCTCGATTTCATCGAGAAGCCGTTCGA
CGACGTGCACCTGCTGGAGCGGGCCGCCGCCGCGGTGGCGCTGGACGAGCAGAATCGCCAGCGCCACGGCCACCAGCGCA
AGGTGTCGGCGGCGCTGGCGCTGCTGACCGAGCGCGAGCGCGAGGTGATGCAGCTGATCCTGGCCGGCAAGCTGAACAAG
CAGATCGCCGAAGAGCTCAGCATCAGCATGAAGACGGTGGAGGTCCACCGCTCGCGGGTGTTCGAGAAGATGGGCGTCAA
GTCCGCGGTGGAGCTGGCCGGCATGCTGGCCGCGCCGGGCGCGCAGGGAGGCAAGATCTAG

Upstream 100 bases:

>100_bases
CTGGCGCTTGTTCAAGCAGCACAATATCGAGATCCCGTTCCCGCAGCGGGAAGTGCGCATCGTCGGCGACAAGCCGGCGC
AGCAGGGCTGAGGAGATATC

Downstream 100 bases:

>100_bases
ATGGGCAGCAAGCAGCCGGTGTCGGTGCTGGTGGTGATACACAGCCGGGATGGCCGGGCGCTGCTGATGGAGCGGGCGGA
CAAGCCCGGCTACTGGCAGT

Product: transcriptional regulatory, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSAKRLAIIDDDEAVRQSLLWLLDGQGYRADGFDSGEAFLADGHGAEYNGIILDLRLSGISGIVLLEKLAQWPYCPPVIM
LTAHGDVPHAVAALKLGALDFIEKPFDDVHLLERAAAAVALDEQNRQRHGHQRKVSAALALLTEREREVMQLILAGKLNK
QIAEELSISMKTVEVHRSRVFEKMGVKSAVELAGMLAAPGAQGGKI

Sequences:

>Translated_206_residues
MSAKRLAIIDDDEAVRQSLLWLLDGQGYRADGFDSGEAFLADGHGAEYNGIILDLRLSGISGIVLLEKLAQWPYCPPVIM
LTAHGDVPHAVAALKLGALDFIEKPFDDVHLLERAAAAVALDEQNRQRHGHQRKVSAALALLTEREREVMQLILAGKLNK
QIAEELSISMKTVEVHRSRVFEKMGVKSAVELAGMLAAPGAQGGKI
>Mature_205_residues
SAKRLAIIDDDEAVRQSLLWLLDGQGYRADGFDSGEAFLADGHGAEYNGIILDLRLSGISGIVLLEKLAQWPYCPPVIML
TAHGDVPHAVAALKLGALDFIEKPFDDVHLLERAAAAVALDEQNRQRHGHQRKVSAALALLTEREREVMQLILAGKLNKQ
IAEELSISMKTVEVHRSRVFEKMGVKSAVELAGMLAAPGAQGGKI

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctR functions as a transcriptional repressor of genes for C4-dicarboxylate transport [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=35.5, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=34.1463414634146, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786747, Length=148, Percent_Identity=27.7027027027027, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788222, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=6e-13,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788712, Length=163, Percent_Identity=28.8343558282209, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22367; Mature: 22236

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKRLAIIDDDEAVRQSLLWLLDGQGYRADGFDSGEAFLADGHGAEYNGIILDLRLSGI
CCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCC
SGIVLLEKLAQWPYCPPVIMLTAHGDVPHAVAALKLGALDFIEKPFDDVHLLERAAAAVA
CHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LDEQNRQRHGHQRKVSAALALLTEREREVMQLILAGKLNKQIAEELSISMKTVEVHRSRV
HCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKMGVKSAVELAGMLAAPGAQGGKI
HHHHCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SAKRLAIIDDDEAVRQSLLWLLDGQGYRADGFDSGEAFLADGHGAEYNGIILDLRLSGI
CCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEEEECCC
SGIVLLEKLAQWPYCPPVIMLTAHGDVPHAVAALKLGALDFIEKPFDDVHLLERAAAAVA
CHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LDEQNRQRHGHQRKVSAALALLTEREREVMQLILAGKLNKQIAEELSISMKTVEVHRSRV
HCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKMGVKSAVELAGMLAAPGAQGGKI
HHHHCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]