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The map label for this gene is hmsR [H]

Identifier: 34498396

GI number: 34498396

Start: 3217102

End: 3218337

Strand: Reverse

Name: hmsR [H]

Synonym: CV_2941

Alternate gene names: 34498396

Gene position: 3218337-3217102 (Counterclockwise)

Preceding gene: 34498397

Following gene: 34498395

Centisome position: 67.74

GC content: 62.86

Gene sequence:

>1236_bases
ATGAACCACTACGTTCTGGATTTCGCCTTTTATTACCCGCTGTTCATGTCCTATCTGTGGATGATAGGCGCGGTGGGGTA
TTACTTGCACTACGAGCGGCATGATCCGCCGCTGGAGCATCCTCCGGATGTCAGCTATCCGCCTGTGACGGTGGTGGTGC
CGTGTTTCAACGAAGAAGCCCACGTCCGCGAAACGCTGTCGCATGCGCTGGCGCTCGACTATCCCGAGTTCGAGGTGATC
GCGGTCAACGACGGCAGCAGGGACGGCACCGCCGCCATCCTGAACCAGATGGCCCAGGAGCATCCCAGACTGCGGGTGAT
CCATCAGGCGCACAACCAGGGCAAGGCGGTGGGCCTCAATACCGCGCTGCTGTTGTCGCGCTACGAGCACCTGATCTGCA
TCGACGGCGACGCGCTGCTCGATCCGCATGCGGCCAAGTGGCTGATGCGCCACTTCCAGCTGGGCTCGCGCGTCGGCGCG
GTGACCGGCAATCCCCGCATCCGCAACCGCACCACGCTGCTGGGCCGGCTGCAGGTAGGGGAGTTCACCTCCATCATCGG
CCTGATCAAGCGCGCGCAGCGCACTTATGGCCGTCTGTTCACCGTGTCCGGGGTCATCGCGGCCTTTCGCAAGACCGCCG
TCGTCCAGGCCGGCTACTGGAGTCCCGACATGCTGACCGAAGACATCGATATCAGCTGGAAGATACAGCTGCAACATTGG
GACGTGCGCTTCGAGCCGCGCGCGCTGGTGTGGATACTGATGCCGGAAACATTGAAGGGCCTGTGGAAGCAGCGGCTGCG
CTGGGCCAAGGGCGGCACCCAGGCCTTGCTGCGCAACAGCGAGATCTTCGGCTCATGGCGGTTTCGCCGCATGTGGCCGG
TGTATGTCGAATATTTCTTCAGCGTGGTGTGGTCGTATGTGATGGCCTTCATCATCATCTGGTGGATAGTGGACGTCTTC
ATCCCCGGTGCGCTCCCACCGGTGGACTCGCCGTTTCTGCCCAATTGGCAGGGGCTGCTGCTGGGCCTGACCTGCCTGCT
GCAATTCATCGTCAGCAAGGCGATAGACAGCCGGTACGACCGGGGCCTGGGGCGCAATTATTTCTGGATGGTGTGGTATC
CGCTGGCCTACTGGCTGGTCAATACCGCCACCACGGTGGTGGCGTTTCCGCAGGCGGCGCTGCGACGCAGCGGCAAGCGC
GCGCGCTGGGTGAGTCCGGACCGGGGAGTACGCTGA

Upstream 100 bases:

>100_bases
GACGCCGCCGGATGGCGGACGCTGAGGCGGGCGTTTTCCCTGGCCGAGACGCCGCGATGACGCGGGCGGCTTGCGGCAAC
GATGCGTCGGAGGAGCGGCG

Downstream 100 bases:

>100_bases
TGGCCACCCCCTTGCATGAGCATGAAGACGACTATCTGATCATTTCCGCCGTGCACAATGTGCCGTGGTGGCGCCGCCTG
CTCGGTTGGCTGGTGACGCT

Product: N-glycosyltransferase

Products: NA

Alternate protein names: PGA synthase; Poly-beta-1,6-GlcNAc synthase; Biofilm PGA synthesis protein PgaC; N-acetylglucosaminyltransferase PgaC [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNHYVLDFAFYYPLFMSYLWMIGAVGYYLHYERHDPPLEHPPDVSYPPVTVVVPCFNEEAHVRETLSHALALDYPEFEVI
AVNDGSRDGTAAILNQMAQEHPRLRVIHQAHNQGKAVGLNTALLLSRYEHLICIDGDALLDPHAAKWLMRHFQLGSRVGA
VTGNPRIRNRTTLLGRLQVGEFTSIIGLIKRAQRTYGRLFTVSGVIAAFRKTAVVQAGYWSPDMLTEDIDISWKIQLQHW
DVRFEPRALVWILMPETLKGLWKQRLRWAKGGTQALLRNSEIFGSWRFRRMWPVYVEYFFSVVWSYVMAFIIIWWIVDVF
IPGALPPVDSPFLPNWQGLLLGLTCLLQFIVSKAIDSRYDRGLGRNYFWMVWYPLAYWLVNTATTVVAFPQAALRRSGKR
ARWVSPDRGVR

Sequences:

>Translated_411_residues
MNHYVLDFAFYYPLFMSYLWMIGAVGYYLHYERHDPPLEHPPDVSYPPVTVVVPCFNEEAHVRETLSHALALDYPEFEVI
AVNDGSRDGTAAILNQMAQEHPRLRVIHQAHNQGKAVGLNTALLLSRYEHLICIDGDALLDPHAAKWLMRHFQLGSRVGA
VTGNPRIRNRTTLLGRLQVGEFTSIIGLIKRAQRTYGRLFTVSGVIAAFRKTAVVQAGYWSPDMLTEDIDISWKIQLQHW
DVRFEPRALVWILMPETLKGLWKQRLRWAKGGTQALLRNSEIFGSWRFRRMWPVYVEYFFSVVWSYVMAFIIIWWIVDVF
IPGALPPVDSPFLPNWQGLLLGLTCLLQFIVSKAIDSRYDRGLGRNYFWMVWYPLAYWLVNTATTVVAFPQAALRRSGKR
ARWVSPDRGVR
>Mature_411_residues
MNHYVLDFAFYYPLFMSYLWMIGAVGYYLHYERHDPPLEHPPDVSYPPVTVVVPCFNEEAHVRETLSHALALDYPEFEVI
AVNDGSRDGTAAILNQMAQEHPRLRVIHQAHNQGKAVGLNTALLLSRYEHLICIDGDALLDPHAAKWLMRHFQLGSRVGA
VTGNPRIRNRTTLLGRLQVGEFTSIIGLIKRAQRTYGRLFTVSGVIAAFRKTAVVQAGYWSPDMLTEDIDISWKIQLQHW
DVRFEPRALVWILMPETLKGLWKQRLRWAKGGTQALLRNSEIFGSWRFRRMWPVYVEYFFSVVWSYVMAFIIIWWIVDVF
IPGALPPVDSPFLPNWQGLLLGLTCLLQFIVSKAIDSRYDRGLGRNYFWMVWYPLAYWLVNTATTVVAFPQAALRRSGKR
ARWVSPDRGVR

Specific function: Probable N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N- acetylglucosamine to produce the linear homopolymer poly-beta-1,6- N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide [H]

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787259, Length=411, Percent_Identity=50.8515815085158, Blast_Score=429, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: NA

Molecular weight: Translated: 47509; Mature: 47509

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHYVLDFAFYYPLFMSYLWMIGAVGYYLHYERHDPPLEHPPDVSYPPVTVVVPCFNEEA
CCCEEEHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEEECCCCHH
HVRETLSHALALDYPEFEVIAVNDGSRDGTAAILNQMAQEHPRLRVIHQAHNQGKAVGLN
HHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHCCCCCEECCH
TALLLSRYEHLICIDGDALLDPHAAKWLMRHFQLGSRVGAVTGNPRIRNRTTLLGRLQVG
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHEEEEECHH
EFTSIIGLIKRAQRTYGRLFTVSGVIAAFRKTAVVQAGYWSPDMLTEDIDISWKIQLQHW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEEC
DVRFEPRALVWILMPETLKGLWKQRLRWAKGGTQALLRNSEIFGSWRFRRMWPVYVEYFF
CEEECCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCHHHHHHHHHHHHHH
SVVWSYVMAFIIIWWIVDVFIPGALPPVDSPFLPNWQGLLLGLTCLLQFIVSKAIDSRYD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGLGRNYFWMVWYPLAYWLVNTATTVVAFPQAALRRSGKRARWVSPDRGVR
CCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNHYVLDFAFYYPLFMSYLWMIGAVGYYLHYERHDPPLEHPPDVSYPPVTVVVPCFNEEA
CCCEEEHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEEECCCCHH
HVRETLSHALALDYPEFEVIAVNDGSRDGTAAILNQMAQEHPRLRVIHQAHNQGKAVGLN
HHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHCCCCCEECCH
TALLLSRYEHLICIDGDALLDPHAAKWLMRHFQLGSRVGAVTGNPRIRNRTTLLGRLQVG
HHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHEEEEECHH
EFTSIIGLIKRAQRTYGRLFTVSGVIAAFRKTAVVQAGYWSPDMLTEDIDISWKIQLQHW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEEC
DVRFEPRALVWILMPETLKGLWKQRLRWAKGGTQALLRNSEIFGSWRFRRMWPVYVEYFF
CEEECCCEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCHHHHHHHHHHHHHH
SVVWSYVMAFIIIWWIVDVFIPGALPPVDSPFLPNWQGLLLGLTCLLQFIVSKAIDSRYD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RGLGRNYFWMVWYPLAYWLVNTATTVVAFPQAALRRSGKRARWVSPDRGVR
CCCCCCEEEEHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]