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The map label for this gene is cbf2 [H]

Identifier: 34498389

GI number: 34498389

Start: 3210964

End: 3211692

Strand: Direct

Name: cbf2 [H]

Synonym: CV_2934

Alternate gene names: 34498389

Gene position: 3210964-3211692 (Clockwise)

Preceding gene: 34498388

Following gene: 34498391

Centisome position: 67.58

GC content: 65.02

Gene sequence:

>729_bases
ATGACCATCACCGTCAATGGCGTCGAAATCAGCGAAGACATGATCGCGTCCCAACTGGACCACTACGCCGACACCCCGAG
CCCGCGCGACACCGCCATCCAGCAACTGATCCTGCACACCCTGCTGATTCAGCAGGCCAAGAGCGAAGGCCTGGACGTGG
CCGACGAGCAGCAGGCGATCCAGACGCTGCTGGACAGCAAGCTGCAGGTGCCCGCCATCGACGAGGCCAGCTGCCGCGAA
TTCTACGACCGCTATCCGGAGCGCTTCAGCGCCGGCGAAAGCGCCGTGGCCAGCCACATCCTGCTGCCGAAGGGCGAAGG
CCTGGAAGCCAGCCTGATCAAGGCCAAGGCTGAAGGCATCCTGGAAGAGGCGCAAGCCAACCCGTCCCGCTTCGCCGCCC
TGGCGCAGGAGCACTCCACCTGCCCGTCCGGCAAGCAAGGCGGCAGCCTCGGCCAGTTCGGCCGCGGCCAGATGGTGCCG
GAATTCGAACAGGCGGTGTTCAGCACCGAAGCCGGCCAGATCACCCCGCACCTGGTGGAAACCCAGTTCGGCTACCACAT
CATCCAGGTGGAGCAGCGCGCCGAAGGCGGCAAGATCGGCTTCGACGAAGTCAAGGAACGCCTGCAGCACTACCTGGCCG
ACCTGGCGGTCAACCAAGCCATGCACGAGTACCTGAACATGCTGGTTTCCGCCGCCCAGATCAGCGGCTACCAGATGACC
GCCGCCTGA

Upstream 100 bases:

>100_bases
CCGCTCATCCGCAGCAGGCCCGCCCTGCCCTTGTCAGCGCTGCCCAGGCAGCCTCATCTGGAAACGCCATGACCTGGCCG
CTCCCCCACAGGAAACTCAC

Downstream 100 bases:

>100_bases
GCGACGATCATCCAGTCATCGCATCACCAGGCCGTCCGCGTCGCGCGGGCGGCCTTTTTCTTGCCCGCCTGCGCGGCGAC
AGGCTGCTGGCGCAGGCTGG

Product: peptidyl-prolyl cis-trans isomerase

Products: peptidylproline (omega=0) [C]

Alternate protein names: Major antigen peb4A [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTITVNGVEISEDMIASQLDHYADTPSPRDTAIQQLILHTLLIQQAKSEGLDVADEQQAIQTLLDSKLQVPAIDEASCRE
FYDRYPERFSAGESAVASHILLPKGEGLEASLIKAKAEGILEEAQANPSRFAALAQEHSTCPSGKQGGSLGQFGRGQMVP
EFEQAVFSTEAGQITPHLVETQFGYHIIQVEQRAEGGKIGFDEVKERLQHYLADLAVNQAMHEYLNMLVSAAQISGYQMT
AA

Sequences:

>Translated_242_residues
MTITVNGVEISEDMIASQLDHYADTPSPRDTAIQQLILHTLLIQQAKSEGLDVADEQQAIQTLLDSKLQVPAIDEASCRE
FYDRYPERFSAGESAVASHILLPKGEGLEASLIKAKAEGILEEAQANPSRFAALAQEHSTCPSGKQGGSLGQFGRGQMVP
EFEQAVFSTEAGQITPHLVETQFGYHIIQVEQRAEGGKIGFDEVKERLQHYLADLAVNQAMHEYLNMLVSAAQISGYQMT
AA
>Mature_241_residues
TITVNGVEISEDMIASQLDHYADTPSPRDTAIQQLILHTLLIQQAKSEGLDVADEQQAIQTLLDSKLQVPAIDEASCREF
YDRYPERFSAGESAVASHILLPKGEGLEASLIKAKAEGILEEAQANPSRFAALAQEHSTCPSGKQGGSLGQFGRGQMVPE
FEQAVFSTEAGQITPHLVETQFGYHIIQVEQRAEGGKIGFDEVKERLQHYLADLAVNQAMHEYLNMLVSAAQISGYQMTA
A

Specific function: Ppiases Accelerate The Folding Of Proteins. It Prefers Amino Acid Residues With Hydrophobic Side Chains Like Leucine And Phenylalanine In The P1 Position Of The Peptides Substrates. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1790211, Length=101, Percent_Identity=46.5346534653465, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: 5.2.1.8 [C]

Molecular weight: Translated: 26387; Mature: 26256

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITVNGVEISEDMIASQLDHYADTPSPRDTAIQQLILHTLLIQQAKSEGLDVADEQQAI
CEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QTLLDSKLQVPAIDEASCREFYDRYPERFSAGESAVASHILLPKGEGLEASLIKAKAEGI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LEEAQANPSRFAALAQEHSTCPSGKQGGSLGQFGRGQMVPEFEQAVFSTEAGQITPHLVE
HHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
TQFGYHIIQVEQRAEGGKIGFDEVKERLQHYLADLAVNQAMHEYLNMLVSAAQISGYQMT
HHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
AA
CC
>Mature Secondary Structure 
TITVNGVEISEDMIASQLDHYADTPSPRDTAIQQLILHTLLIQQAKSEGLDVADEQQAI
EEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QTLLDSKLQVPAIDEASCREFYDRYPERFSAGESAVASHILLPKGEGLEASLIKAKAEGI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LEEAQANPSRFAALAQEHSTCPSGKQGGSLGQFGRGQMVPEFEQAVFSTEAGQITPHLVE
HHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHH
TQFGYHIIQVEQRAEGGKIGFDEVKERLQHYLADLAVNQAMHEYLNMLVSAAQISGYQMT
HHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Peptidoproline (omega=180) [C]

Specific reaction: Peptidoproline (omega=180) = peptidylproline (omega=0) [C]

General reaction: Rotation (Single bond) [C]

Inhibitor: cyclosporins [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]