Click here to switch to the map view.

The map label for this gene is holC [H]

Identifier: 34498368

GI number: 34498368

Start: 3192227

End: 3192652

Strand: Reverse

Name: holC [H]

Synonym: CV_2913

Alternate gene names: 34498368

Gene position: 3192652-3192227 (Counterclockwise)

Preceding gene: 34498369

Following gene: 34498367

Centisome position: 67.2

GC content: 60.8

Gene sequence:

>426_bases
ATGAGCAGGATTGATTTTTATACCAATGTCGCCGACCCGCAGGCTTTTGCCTGCAGGTTGGCCGATACCGTGCAGCGCAA
GAAGGAAAGGTTGCTGATCTGGCTGGACAGTGAGCGCAGCGTCGAGGTGTTCAGCAACCGCTTGTGGAGTTTCGGCGATA
CCCGCTTCGTGCCGCATTGCCGGCTTGGCGCCCCGGAGGCGGCCGAGACGCCGGTTTGGCTGGCCGCCAGCCTGCCCGAC
GATCTGTCCCATCCGGTATTGCTGAATCTGGGGCCGCAGTTGCCCTTTGAATTCGGCAGGTTTGAGCGCATTCTTGAAAT
AGTGGGACGCGACCCCGAGTCGCTGGCCACCGCCCGCGAGCGCTTCCGTGCCTACCGTGAGCACGGCTGCGAAATCGAAC
ATCACGACATGAGTCAAACGCCATGA

Upstream 100 bases:

>100_bases
CCGCTCCTGGTGCAGTTCCTGCAAGACCGCGCCGACATCGCGCTGGGCAACGTGGTGCGCCGCGGCCGTCCGCGCCGCGA
GGCGCCCGAAGTGGCAGACG

Downstream 100 bases:

>100_bases
CTGAGTCGCCGAAAGCCAACGAGCCCGACTGGAGCGGCCTCAACCTGCCGGTCCTGACCGAAGTGGTGGACGAGCAGGCC
GTTCCGACATTGGCCGAGGA

Product: DNA polymerase III subunit chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MSRIDFYTNVADPQAFACRLADTVQRKKERLLIWLDSERSVEVFSNRLWSFGDTRFVPHCRLGAPEAAETPVWLAASLPD
DLSHPVLLNLGPQLPFEFGRFERILEIVGRDPESLATARERFRAYREHGCEIEHHDMSQTP

Sequences:

>Translated_141_residues
MSRIDFYTNVADPQAFACRLADTVQRKKERLLIWLDSERSVEVFSNRLWSFGDTRFVPHCRLGAPEAAETPVWLAASLPD
DLSHPVLLNLGPQLPFEFGRFERILEIVGRDPESLATARERFRAYREHGCEIEHHDMSQTP
>Mature_140_residues
SRIDFYTNVADPQAFACRLADTVQRKKERLLIWLDSERSVEVFSNRLWSFGDTRFVPHCRLGAPEAAETPVWLAASLPDD
LSHPVLLNLGPQLPFEFGRFERILEIVGRDPESLATARERFRAYREHGCEIEHHDMSQTP

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16267; Mature: 16135

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIDFYTNVADPQAFACRLADTVQRKKERLLIWLDSERSVEVFSNRLWSFGDTRFVPHC
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCCCCCCC
RLGAPEAAETPVWLAASLPDDLSHPVLLNLGPQLPFEFGRFERILEIVGRDPESLATARE
CCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
RFRAYREHGCEIEHHDMSQTP
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SRIDFYTNVADPQAFACRLADTVQRKKERLLIWLDSERSVEVFSNRLWSFGDTRFVPHC
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHCCCCCCCCCCC
RLGAPEAAETPVWLAASLPDDLSHPVLLNLGPQLPFEFGRFERILEIVGRDPESLATARE
CCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
RFRAYREHGCEIEHHDMSQTP
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9864319; 10984043 [H]