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The map label for this gene is aspA [H]

Identifier: 34498172

GI number: 34498172

Start: 2942787

End: 2944559

Strand: Direct

Name: aspA [H]

Synonym: CV_2717

Alternate gene names: 34498172

Gene position: 2942787-2944559 (Clockwise)

Preceding gene: 34498171

Following gene: 34498173

Centisome position: 61.94

GC content: 65.09

Gene sequence:

>1773_bases
ATGCTGGCGCTGGCCTCGCTGGCCAGCCATGCCGCCCCGTCCGCGCCGGATCGCAGCGTCCCGCTGCTGCCGGGCGACCC
ACTGGCCAATCAACAATGGCATCTGAAGAACACCGGCCAGACTGCCTTCTCCAAGCGCGGCGGCGTCAAGGGCGTCGATC
TCAACCTCGCGTTCACCCATCTGCGCGGCATCCGCGGACTCGGCACCACCATCGCCGTGATCGACGACGGCCTGGAGATC
AAGCACCCCGATCTGGCGGCCAACATCGTGCCCGGCTCCAAAAACCTGGTGGACGGCAGCAATGACCCGAGCCCCTCCGG
TGACAATGGCCACGGCACCGCCGTGGCGGGCATCGCCGCCGCGGTGGCCTTCAACGGCATAGGCGGCCGCGGCATCGCGC
CTTCCGCCGGCCTGAAAGGCTTCAACTGGCTGCTGAACCAAACGCTGGACGGCTGGTTGCTGGCCCACGGCAAGAAACCC
AATGGCGGTCCGCTGGAAGCCTTCACCGACGCCCGGGTCTTCAACCAGAGTTACGGCTCCTCCACCATCACCTCGGTTCC
CGCCAATCCGGATCAGGACATCGAGCTGAAGACCGAGGAGGAAACCTACGAGGACATCAGCCGCAACAGCCACTGGGGGC
GCGGCGCGGTCTTCGTCAAATCGGCCGGTAATGCCTACAACTCCTTCCGCCTGAACCAGACCGAGTCCCTGCTCGGTTAT
CAGGGCAATAACGGCCTGCCGATACAGGACTCCAACCTGACTTCCGACAACAACAACTACTGGAACGTGGTGGTATCGGC
GCTGAACGCGGACGGCGTGCGCTCCTCGTACTCGTCGGTCGGCGCCAACGTGCTGCTCACCGCGCCAGGCGGCGAATACG
GCACCGACTCCCCGGCCATGGTCACCACCGACCTGTCCGGCTGCGCCCGCGGCTACAACGTCACCGGCAACACCGCCAAC
GGCCTGCACGGCGGCACCGCGCTGGACCCGAACTGCGACTACAACGGCGTCATGAACGGCACCTCGTCCGCGGCGCCGTC
CACCTCCGGCTCCTTCGCCGTCGTGATGTCGGCCAACCCCGCCCTGTCCGCCCGCGACGTGCGCCACATCCTGATCACCA
CCGCTCGCCAGGTTGACGCGGCGAATCCGGGCGTGACGCTCGCCTTCAAGGACAAGAACGGCGGCGCGCACAGCTACCAG
GCGATCCCCGGCTGGCAGAAGAATGCCGCCGGCCTGCCCTTCCACCCGTTCTACGGCTTTGGTCTGATCAATATCGACAA
AGCGGTGGAAAAGGCTTTGTTCTACAACAAGCCGCTGCCGCCGCTGCAAAAGACCCGCTGGGAAACCGTATCCGCCCAGA
CCGCCATTCCCGACGCCGATGAAAAAGGCGTGGAAAGCGTGTACAACCAGCCGGCAGACCTGACCGTGGAAGCCGTCCAG
ATCCTGGTCGATGCCGAACACGGCCGCGCCAACGATCTGGCGGTGGAACTGATCTCCCCGTCCGGCACCCGCTCGGTGCT
GCTGTCTCCGCGCACCTCCCTGGTTGGCGAAACCTATGGCCTCAACCAGCAGCGCCTGCTGTCCAATCAGTTCTACGGCG
AACAGGCCAAGGGCCAGTGGCGGCTGCGCGTGATCGACACCAATGGCGGCCAGTACCAATACGTGATCCGCAATCGCAAC
ACCGGCGCCAACACCGTCTATTCCCTGCCTAACGCGGAAGGTAAACTGAAATCGTGGTCGATCCGCTTCTTCGGCCACCG
GAGCGCAGCATGA

Upstream 100 bases:

>100_bases
AAAATTAACACATATGATCCTCTGGCGGTCACATCCGCAAAACACAAAGGCAAAATAGAGGATCTCAATCATGCACGTTC
GCATCACCAGCAGCGCCGTC

Downstream 100 bases:

>100_bases
AAGCCATCATCCGACTCATTCCCCTCGCCCTGCTGACCCTGGCCGTCCACAGCCAGGCCGCCGAGCCCGCCTTCCTGGCC
CAGCCGGCAGGACAAGCTGT

Product: extracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MLALASLASHAAPSAPDRSVPLLPGDPLANQQWHLKNTGQTAFSKRGGVKGVDLNLAFTHLRGIRGLGTTIAVIDDGLEI
KHPDLAANIVPGSKNLVDGSNDPSPSGDNGHGTAVAGIAAAVAFNGIGGRGIAPSAGLKGFNWLLNQTLDGWLLAHGKKP
NGGPLEAFTDARVFNQSYGSSTITSVPANPDQDIELKTEEETYEDISRNSHWGRGAVFVKSAGNAYNSFRLNQTESLLGY
QGNNGLPIQDSNLTSDNNNYWNVVVSALNADGVRSSYSSVGANVLLTAPGGEYGTDSPAMVTTDLSGCARGYNVTGNTAN
GLHGGTALDPNCDYNGVMNGTSSAAPSTSGSFAVVMSANPALSARDVRHILITTARQVDAANPGVTLAFKDKNGGAHSYQ
AIPGWQKNAAGLPFHPFYGFGLINIDKAVEKALFYNKPLPPLQKTRWETVSAQTAIPDADEKGVESVYNQPADLTVEAVQ
ILVDAEHGRANDLAVELISPSGTRSVLLSPRTSLVGETYGLNQQRLLSNQFYGEQAKGQWRLRVIDTNGGQYQYVIRNRN
TGANTVYSLPNAEGKLKSWSIRFFGHRSAA

Sequences:

>Translated_590_residues
MLALASLASHAAPSAPDRSVPLLPGDPLANQQWHLKNTGQTAFSKRGGVKGVDLNLAFTHLRGIRGLGTTIAVIDDGLEI
KHPDLAANIVPGSKNLVDGSNDPSPSGDNGHGTAVAGIAAAVAFNGIGGRGIAPSAGLKGFNWLLNQTLDGWLLAHGKKP
NGGPLEAFTDARVFNQSYGSSTITSVPANPDQDIELKTEEETYEDISRNSHWGRGAVFVKSAGNAYNSFRLNQTESLLGY
QGNNGLPIQDSNLTSDNNNYWNVVVSALNADGVRSSYSSVGANVLLTAPGGEYGTDSPAMVTTDLSGCARGYNVTGNTAN
GLHGGTALDPNCDYNGVMNGTSSAAPSTSGSFAVVMSANPALSARDVRHILITTARQVDAANPGVTLAFKDKNGGAHSYQ
AIPGWQKNAAGLPFHPFYGFGLINIDKAVEKALFYNKPLPPLQKTRWETVSAQTAIPDADEKGVESVYNQPADLTVEAVQ
ILVDAEHGRANDLAVELISPSGTRSVLLSPRTSLVGETYGLNQQRLLSNQFYGEQAKGQWRLRVIDTNGGQYQYVIRNRN
TGANTVYSLPNAEGKLKSWSIRFFGHRSAA
>Mature_590_residues
MLALASLASHAAPSAPDRSVPLLPGDPLANQQWHLKNTGQTAFSKRGGVKGVDLNLAFTHLRGIRGLGTTIAVIDDGLEI
KHPDLAANIVPGSKNLVDGSNDPSPSGDNGHGTAVAGIAAAVAFNGIGGRGIAPSAGLKGFNWLLNQTLDGWLLAHGKKP
NGGPLEAFTDARVFNQSYGSSTITSVPANPDQDIELKTEEETYEDISRNSHWGRGAVFVKSAGNAYNSFRLNQTESLLGY
QGNNGLPIQDSNLTSDNNNYWNVVVSALNADGVRSSYSSVGANVLLTAPGGEYGTDSPAMVTTDLSGCARGYNVTGNTAN
GLHGGTALDPNCDYNGVMNGTSSAAPSTSGSFAVVMSANPALSARDVRHILITTARQVDAANPGVTLAFKDKNGGAHSYQ
AIPGWQKNAAGLPFHPFYGFGLINIDKAVEKALFYNKPLPPLQKTRWETVSAQTAIPDADEKGVESVYNQPADLTVEAVQ
ILVDAEHGRANDLAVELISPSGTRSVLLSPRTSLVGETYGLNQQRLLSNQFYGEQAKGQWRLRVIDTNGGQYQYVIRNRN
TGANTVYSLPNAEGKLKSWSIRFFGHRSAA

Specific function: Agent of furonculosis [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI20336242, Length=542, Percent_Identity=26.7527675276753, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI295424143, Length=542, Percent_Identity=26.7527675276753, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI20336244, Length=585, Percent_Identity=24.6153846153846, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI299523015, Length=562, Percent_Identity=25.2669039145907, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI20336180, Length=599, Percent_Identity=25.542570951586, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI4505577, Length=602, Percent_Identity=25.5813953488372, Blast_Score=134, Evalue=4e-31,
Organism=Homo sapiens, GI20336184, Length=592, Percent_Identity=25.6756756756757, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI20336182, Length=592, Percent_Identity=25.6756756756757, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI20336246, Length=589, Percent_Identity=24.7877758913413, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI76443679, Length=565, Percent_Identity=26.9026548672566, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4505579, Length=555, Percent_Identity=25.7657657657658, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI20336188, Length=561, Percent_Identity=25.4901960784314, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI27894285, Length=561, Percent_Identity=25.4901960784314, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI20336190, Length=561, Percent_Identity=25.4901960784314, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI20336248, Length=585, Percent_Identity=26.6666666666667, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI295424145, Length=233, Percent_Identity=30.0429184549356, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI20336186, Length=404, Percent_Identity=26.4851485148515, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987206, Length=553, Percent_Identity=25.8589511754069, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71988312, Length=601, Percent_Identity=27.1214642262895, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71988308, Length=602, Percent_Identity=26.9102990033223, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71988321, Length=602, Percent_Identity=26.9102990033223, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71988315, Length=597, Percent_Identity=27.4706867671692, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71988297, Length=597, Percent_Identity=27.4706867671692, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71988301, Length=597, Percent_Identity=27.4706867671692, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI25141268, Length=543, Percent_Identity=25.5985267034991, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71987215, Length=469, Percent_Identity=23.8805970149254, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71983555, Length=593, Percent_Identity=23.9460370994941, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17505240, Length=488, Percent_Identity=27.0491803278689, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324091, Length=548, Percent_Identity=25, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24642488, Length=595, Percent_Identity=25.8823529411765, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24642484, Length=595, Percent_Identity=25.8823529411765, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24642486, Length=595, Percent_Identity=25.8823529411765, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17136192, Length=538, Percent_Identity=25.4646840148699, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI281360987, Length=595, Percent_Identity=25.546218487395, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24642494, Length=595, Percent_Identity=25.546218487395, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24642490, Length=595, Percent_Identity=25.546218487395, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI45555723, Length=595, Percent_Identity=25.546218487395, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24642492, Length=595, Percent_Identity=25.546218487395, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24650058, Length=523, Percent_Identity=25.8126195028681, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24650060, Length=523, Percent_Identity=25.8126195028681, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI45553513, Length=523, Percent_Identity=25.8126195028681, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI17864552, Length=552, Percent_Identity=25.1811594202899, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI45553515, Length=523, Percent_Identity=25.8126195028681, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24650056, Length=523, Percent_Identity=25.6214149139579, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281360985, Length=144, Percent_Identity=38.8888888888889, Blast_Score=87, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 62339; Mature: 62339

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALASLASHAAPSAPDRSVPLLPGDPLANQQWHLKNTGQTAFSKRGGVKGVDLNLAFTH
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCEEEEEEEEHH
LRGIRGLGTTIAVIDDGLEIKHPDLAANIVPGSKNLVDGSNDPSPSGDNGHGTAVAGIAA
HHCCCCCCCEEEEEECCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AVAFNGIGGRGIAPSAGLKGFNWLLNQTLDGWLLAHGKKPNGGPLEAFTDARVFNQSYGS
HHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCC
STITSVPANPDQDIELKTEEETYEDISRNSHWGRGAVFVKSAGNAYNSFRLNQTESLLGY
CEEEECCCCCCCCEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCHHHHHEE
QGNNGLPIQDSNLTSDNNNYWNVVVSALNADGVRSSYSSVGANVLLTAPGGEYGTDSPAM
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCEEEEECCCCCCCCCCCCE
VTTDLSGCARGYNVTGNTANGLHGGTALDPNCDYNGVMNGTSSAAPSTSGSFAVVMSANP
EEECHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
ALSARDVRHILITTARQVDAANPGVTLAFKDKNGGAHSYQAIPGWQKNAAGLPFHPFYGF
CCCHHHHEEEEEEEHHHHCCCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCCC
GLINIDKAVEKALFYNKPLPPLQKTRWETVSAQTAIPDADEKGVESVYNQPADLTVEAVQ
EEEEHHHHHHHHHHHCCCCCCHHHHCHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEE
ILVDAEHGRANDLAVELISPSGTRSVLLSPRTSLVGETYGLNQQRLLSNQFYGEQAKGQW
EEEECCCCCCCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHCCCCCCCEE
RLRVIDTNGGQYQYVIRNRNTGANTVYSLPNAEGKLKSWSIRFFGHRSAA
EEEEEECCCCEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MLALASLASHAAPSAPDRSVPLLPGDPLANQQWHLKNTGQTAFSKRGGVKGVDLNLAFTH
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHCCCCCEEEEEEEEHH
LRGIRGLGTTIAVIDDGLEIKHPDLAANIVPGSKNLVDGSNDPSPSGDNGHGTAVAGIAA
HHCCCCCCCEEEEEECCCEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AVAFNGIGGRGIAPSAGLKGFNWLLNQTLDGWLLAHGKKPNGGPLEAFTDARVFNQSYGS
HHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCC
STITSVPANPDQDIELKTEEETYEDISRNSHWGRGAVFVKSAGNAYNSFRLNQTESLLGY
CEEEECCCCCCCCEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCEEECCCHHHHHEE
QGNNGLPIQDSNLTSDNNNYWNVVVSALNADGVRSSYSSVGANVLLTAPGGEYGTDSPAM
CCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHCCCEEEEECCCCCCCCCCCCE
VTTDLSGCARGYNVTGNTANGLHGGTALDPNCDYNGVMNGTSSAAPSTSGSFAVVMSANP
EEECHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCC
ALSARDVRHILITTARQVDAANPGVTLAFKDKNGGAHSYQAIPGWQKNAAGLPFHPFYGF
CCCHHHHEEEEEEEHHHHCCCCCCEEEEEECCCCCCCCEECCCCCCCCCCCCCCCCCCCC
GLINIDKAVEKALFYNKPLPPLQKTRWETVSAQTAIPDADEKGVESVYNQPADLTVEAVQ
EEEEHHHHHHHHHHHCCCCCCHHHHCHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEE
ILVDAEHGRANDLAVELISPSGTRSVLLSPRTSLVGETYGLNQQRLLSNQFYGEQAKGQW
EEEECCCCCCCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHCCCCCCCEE
RLRVIDTNGGQYQYVIRNRNTGANTVYSLPNAEGKLKSWSIRFFGHRSAA
EEEEEECCCCEEEEEEECCCCCCCEEEECCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1468618 [H]