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The map label for this gene is fabH [H]

Identifier: 34497901

GI number: 34497901

Start: 2631465

End: 2632436

Strand: Direct

Name: fabH [H]

Synonym: CV_2446

Alternate gene names: 34497901

Gene position: 2631465-2632436 (Clockwise)

Preceding gene: 34497900

Following gene: 34497902

Centisome position: 55.39

GC content: 67.18

Gene sequence:

>972_bases
ATGAATTTGATTGCAACCGGCAAAGCACTGCCGAGCCATCCCGTCACCGCTGACGATCTTGACATCAAGCTTGGCTGCCG
CCGCGGCCATACCCTGAAGAAAAGCGGCGTCCACACCCGGCATTTCGCCGGCGACCACGAGTCGCAAAGCCTGCTGGGCG
CCCGCGCGCTGAACGATGCTTTGGCGCGCGCGGCAATGCAAGCGTCGGAGATAGACTTGCTGATCGGCGCCTGCGGCATT
CCGGAGCAGGCCTTGCCCGGCACCGCCAGCTTCATCGCCCATGCCGCCGGGCTGCCCGCCGGCCTGCCCGCTTTCGACGT
CAATACCAGTTGTCTCAGCTTTCTGTCCGCGCTGCAGGTGGCGGACAGCCTGTTGCTGTCGGGCGCGTATCGCCGAATTG
CCATCGTATCGGCCGACCTGGCCTCGCGCGGCCTGAACTGGGCCGATCCCGAGGCTTCGCTGATCTTCGGCGATGGGGCG
GCGGCGGCCATCGTCGAGCGCTCGGCGCCGGGCCACGGCCTGAAGACTTTCAAGCTGGCCACCTATCCGGAAGGCCGCAA
CTTCTGCGAGATACGCGCGGGCGGCACCCAGCGCAACCCGCGCCGCGGCGTCGCGGACGGGGATTTCCTGTTCGACATGA
ACGGCAAGGCGGTTTTCAAGCTGGCATCGCGATTGATGCCGGACTTCCTGGATGCGTTGATGGATGCCACGCCGGGCGGA
CTGAACAGCATAGATTGCGTGGTGCCCCATCAGGCCAGCCACCTGGGCATGCAGCACATGGCCAAGCGCCTGGGCATCGC
CGCCGGCCGCATCGTCGACATCTACGCCTCGCACGGCAACCAGGTGGCGGCCTCGCTGCCCACCGCGCTGCACGAGGCCT
TTGTCGACGGCCGCGCCCGCGCCGGCAAGCGCCTGCTGATGGTGGGCACGGCGGCGGGCCTCAACCTGGGCGGGCTGGTA
TGGGATCTGTGA

Upstream 100 bases:

>100_bases
GCGCTCCGCATGCTTGAATGATTTTTATGTGAACGGACTTGTCTGAAAATGTTCCAGTGCATGAAAATGCGGCCGAATCT
GAATTGCACCTTGAGCCTGA

Downstream 100 bases:

>100_bases
CGCGGGTGCTGGTCACCGGCGCCACCGGCGGCCTGGGGCGCAATGCCGTCGCCCACTTGCTGGACAGGGGATGCGCGGTG
CGCGCCACTGGGCGCAACCT

Product: 3-oxoacyl-ACP synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MNLIATGKALPSHPVTADDLDIKLGCRRGHTLKKSGVHTRHFAGDHESQSLLGARALNDALARAAMQASEIDLLIGACGI
PEQALPGTASFIAHAAGLPAGLPAFDVNTSCLSFLSALQVADSLLLSGAYRRIAIVSADLASRGLNWADPEASLIFGDGA
AAAIVERSAPGHGLKTFKLATYPEGRNFCEIRAGGTQRNPRRGVADGDFLFDMNGKAVFKLASRLMPDFLDALMDATPGG
LNSIDCVVPHQASHLGMQHMAKRLGIAAGRIVDIYASHGNQVAASLPTALHEAFVDGRARAGKRLLMVGTAAGLNLGGLV
WDL

Sequences:

>Translated_323_residues
MNLIATGKALPSHPVTADDLDIKLGCRRGHTLKKSGVHTRHFAGDHESQSLLGARALNDALARAAMQASEIDLLIGACGI
PEQALPGTASFIAHAAGLPAGLPAFDVNTSCLSFLSALQVADSLLLSGAYRRIAIVSADLASRGLNWADPEASLIFGDGA
AAAIVERSAPGHGLKTFKLATYPEGRNFCEIRAGGTQRNPRRGVADGDFLFDMNGKAVFKLASRLMPDFLDALMDATPGG
LNSIDCVVPHQASHLGMQHMAKRLGIAAGRIVDIYASHGNQVAASLPTALHEAFVDGRARAGKRLLMVGTAAGLNLGGLV
WDL
>Mature_323_residues
MNLIATGKALPSHPVTADDLDIKLGCRRGHTLKKSGVHTRHFAGDHESQSLLGARALNDALARAAMQASEIDLLIGACGI
PEQALPGTASFIAHAAGLPAGLPAFDVNTSCLSFLSALQVADSLLLSGAYRRIAIVSADLASRGLNWADPEASLIFGDGA
AAAIVERSAPGHGLKTFKLATYPEGRNFCEIRAGGTQRNPRRGVADGDFLFDMNGKAVFKLASRLMPDFLDALMDATPGG
LNSIDCVVPHQASHLGMQHMAKRLGIAAGRIVDIYASHGNQVAASLPTALHEAFVDGRARAGKRLLMVGTAAGLNLGGLV
WDL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=316, Percent_Identity=31.0126582278481, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 33710; Mature: 33710

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIATGKALPSHPVTADDLDIKLGCRRGHTLKKSGVHTRHFAGDHESQSLLGARALNDA
CCEEECCCCCCCCCCCCCCCEEEEECCCCCCCHHCCCCHHHCCCCCCHHHHHHHHHHHHH
LARAAMQASEIDLLIGACGIPEQALPGTASFIAHAAGLPAGLPAFDVNTSCLSFLSALQV
HHHHHHHHHHCEEEEECCCCCHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
ADSLLLSGAYRRIAIVSADLASRGLNWADPEASLIFGDGAAAAIVERSAPGHGLKTFKLA
HHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEE
TYPEGRNFCEIRAGGTQRNPRRGVADGDFLFDMNGKAVFKLASRLMPDFLDALMDATPGG
ECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
LNSIDCVVPHQASHLGMQHMAKRLGIAAGRIVDIYASHGNQVAASLPTALHEAFVDGRAR
CCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCHHH
AGKRLLMVGTAAGLNLGGLVWDL
CCCEEEEEEECCCCCCCCEEECC
>Mature Secondary Structure
MNLIATGKALPSHPVTADDLDIKLGCRRGHTLKKSGVHTRHFAGDHESQSLLGARALNDA
CCEEECCCCCCCCCCCCCCCEEEEECCCCCCCHHCCCCHHHCCCCCCHHHHHHHHHHHHH
LARAAMQASEIDLLIGACGIPEQALPGTASFIAHAAGLPAGLPAFDVNTSCLSFLSALQV
HHHHHHHHHHCEEEEECCCCCHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
ADSLLLSGAYRRIAIVSADLASRGLNWADPEASLIFGDGAAAAIVERSAPGHGLKTFKLA
HHHHHHHCCCCEEEEEEHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEE
TYPEGRNFCEIRAGGTQRNPRRGVADGDFLFDMNGKAVFKLASRLMPDFLDALMDATPGG
ECCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
LNSIDCVVPHQASHLGMQHMAKRLGIAAGRIVDIYASHGNQVAASLPTALHEAFVDGRAR
CCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEHHHHHHHHHHHHHCCHHH
AGKRLLMVGTAAGLNLGGLVWDL
CCCEEEEEEECCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA