Click here to switch to the map view.

The map label for this gene is kptA [H]

Identifier: 34497880

GI number: 34497880

Start: 2608599

End: 2609228

Strand: Direct

Name: kptA [H]

Synonym: CV_2425

Alternate gene names: 34497880

Gene position: 2608599-2609228 (Clockwise)

Preceding gene: 34497871

Following gene: 34497881

Centisome position: 54.91

GC content: 64.6

Gene sequence:

>630_bases
ATGGGGGCATGCCCGCGTTTTGAAAGAGCATCCGCGCGCGGTATGATTGCGCGAAACCCAATCAAGCAAGATCCTGCCAT
GCGCAATACGCAAGACGACCATTCGCGTTTTCTCAGCCTGGTACTGAGGCATCAACCGGAAACCATAGGATTGCAACTGG
ACGACCAGGGCTGGGCCGATATCGGCGAGCTGCTGGCCAGGCTTGCCGCCAAGGGCCGGAACTTGGGCCGCAAGCAACTG
GAGAAGATTGTTCTCGACAACGACAAGCAGCGGTTCGCCATCAGCGAGGATGGACTGCGCATCCGCGCCAACCAGGGCCA
CTCGATCAAGATAGATCTGGGCCTGGCGGCCTGCGAGCCGCCCGACAGGCTGTACCACGGCACCGCCAGCCGGTTCCTCG
ACGCCATCCTGGCCGAAGGGCTGCGGCCAGGCCAGCGCCAGCATGTCCATCTTTCCGCCGACGGGCAGACCGCGCGCAAG
GTGGGCGCGCGCCACGGCAAGCCCGTGGTGCTGGAGATCGATGCCCGCGCGATGCGGCAGGCCGGGCTGGCGTTCTACCG
CTCCGACAACGGCGTCTGGCTGATCGACGGCGTGCCGCCGGTCTTCATCCGTCAAACCGAAGCGCGATAG

Upstream 100 bases:

>100_bases
GGCCTCCTCGAGGAACAGGGTGATCTTGTGGCCGTTGGGCGTGGTCCAGTAATGAAGGTCTATCATCGTTCGCCTCCTGG
ATGGGAATGGAAAGAATGAC

Downstream 100 bases:

>100_bases
GGCCGGAACATGTGCGTCAACTTCATTCCGCCCAGCCGCGGCCAGCTACGTGAATGGTTAGGCTGCGACCCCGGCGACGG
GCAATGGCCGGACGAGGCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MGACPRFERASARGMIARNPIKQDPAMRNTQDDHSRFLSLVLRHQPETIGLQLDDQGWADIGELLARLAAKGRNLGRKQL
EKIVLDNDKQRFAISEDGLRIRANQGHSIKIDLGLAACEPPDRLYHGTASRFLDAILAEGLRPGQRQHVHLSADGQTARK
VGARHGKPVVLEIDARAMRQAGLAFYRSDNGVWLIDGVPPVFIRQTEAR

Sequences:

>Translated_209_residues
MGACPRFERASARGMIARNPIKQDPAMRNTQDDHSRFLSLVLRHQPETIGLQLDDQGWADIGELLARLAAKGRNLGRKQL
EKIVLDNDKQRFAISEDGLRIRANQGHSIKIDLGLAACEPPDRLYHGTASRFLDAILAEGLRPGQRQHVHLSADGQTARK
VGARHGKPVVLEIDARAMRQAGLAFYRSDNGVWLIDGVPPVFIRQTEAR
>Mature_208_residues
GACPRFERASARGMIARNPIKQDPAMRNTQDDHSRFLSLVLRHQPETIGLQLDDQGWADIGELLARLAAKGRNLGRKQLE
KIVLDNDKQRFAISEDGLRIRANQGHSIKIDLGLAACEPPDRLYHGTASRFLDAILAEGLRPGQRQHVHLSADGQTARKV
GARHGKPVVLEIDARAMRQAGLAFYRSDNGVWLIDGVPPVFIRQTEAR

Specific function: Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP- ribosy

COG id: COG1859

COG function: function code J; RNA:NAD 2'-phosphotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kptA/TPT1 family [H]

Homologues:

Organism=Homo sapiens, GI238550157, Length=203, Percent_Identity=34.9753694581281, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI238550153, Length=203, Percent_Identity=34.9753694581281, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI238550149, Length=205, Percent_Identity=33.6585365853659, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI238550169, Length=204, Percent_Identity=35.2941176470588, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI238550165, Length=156, Percent_Identity=36.5384615384615, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI13899325, Length=152, Percent_Identity=34.2105263157895, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI87082424, Length=172, Percent_Identity=52.3255813953488, Blast_Score=181, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6324470, Length=190, Percent_Identity=33.1578947368421, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022928
- InterPro:   IPR002745 [H]

Pfam domain/function: PF01885 PTS_2-RNA [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 23235; Mature: 23104

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGACPRFERASARGMIARNPIKQDPAMRNTQDDHSRFLSLVLRHQPETIGLQLDDQGWAD
CCCCCCCHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHH
IGELLARLAAKGRNLGRKQLEKIVLDNDKQRFAISEDGLRIRANQGHSIKIDLGLAACEP
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEEECEECCCC
PDRLYHGTASRFLDAILAEGLRPGQRQHVHLSADGQTARKVGARHGKPVVLEIDARAMRQ
HHHHHHCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECHHHHHH
AGLAFYRSDNGVWLIDGVPPVFIRQTEAR
HCEEEEECCCCEEEECCCCCEEEEECCCC
>Mature Secondary Structure 
GACPRFERASARGMIARNPIKQDPAMRNTQDDHSRFLSLVLRHQPETIGLQLDDQGWAD
CCCCCCHHHCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHH
IGELLARLAAKGRNLGRKQLEKIVLDNDKQRFAISEDGLRIRANQGHSIKIDLGLAACEP
HHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCEEEEECCCCEEEEEECEECCCC
PDRLYHGTASRFLDAILAEGLRPGQRQHVHLSADGQTARKVGARHGKPVVLEIDARAMRQ
HHHHHHCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEECHHHHHH
AGLAFYRSDNGVWLIDGVPPVFIRQTEAR
HCEEEEECCCCEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]