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The map label for this gene is fabG [H]

Identifier: 34497713

GI number: 34497713

Start: 2447781

End: 2448626

Strand: Direct

Name: fabG [H]

Synonym: CV_2258

Alternate gene names: 34497713

Gene position: 2447781-2448626 (Clockwise)

Preceding gene: 34497712

Following gene: 34497714

Centisome position: 51.52

GC content: 59.46

Gene sequence:

>846_bases
ATGACGCAGGAAAATACCAAGCACGGCAAGCTGGCAGGCAAAACCATGATCGTGGTCGGCGGGGCCAGAGGCATAGGCGC
CGCCATAGTCGAGGCGCTGGCCCGGCAAGAGGTCAAGGTGTCCATTTTTGACACCGACCGCGCGCCGACGGCCACCAACC
ATTACCAGAGTCGGGATATCAGCGGCTATCAGGCCGCTTGCCAACTGGCTGAGAAGCTGGCGGCACAGGGATTGTCGGTT
CAGGCCATGGCGGTCGACGCTACCGCGGAATCCCAGGTGGTTGAGGCCGTGGACCTTGTCGCCCACGCTGCCGAAGACTT
TTACGGATTGGTGAACGCGATCGGCAGCAGCCATGTGGCGAACACGGTTGACTCTTCGCTAAGCGAATTCGAGGCTATTT
TGCAGACCAATCTTACCGCGCCCTATCTGACCTCCCGCGAGGCCGCGCGAATCCTGGTAAGGCAAGGAAGGGGCGGGGCC
ATTCTCAACATCAGCTCTATCGCCGCCAAGCTCGCGTTCCCCGGCATTTCCGCTTATTGCGCGGCCAAGTCCGGTTTGCA
GGGGTTTTCCGGCGCGCTTGCGCTGGAGCTGGCCCCTCATAATGTTCGGGTCAACTGCGTGTGCCCAGGCATAGTCAAGA
CCAATATGTGGAAGTATCTGGAAAACCAATTGATGGGGCCCGGGGAAAATCTGGAGCAATTATGGGCGAGGATGGAGGGC
TTGATCCCGCTGGGCCGCACTCAGACAGCGGCCAATATCGCGCGCTTCTGCGTGGCAATACTCGAGAACGAGGATATTAC
CGCCCAGTCGCTGTCCGTTGATGGCGGGATGAATCTCTATGGTTGA

Upstream 100 bases:

>100_bases
GCTAGTCGCCTCGACTTCGCGCTCCGCTTTCCCTTTTCATTGTTTTCCGAATCCCGACAGGGCTTCGGCCACCCTTCTAT
TAACCGAGGAGTGATGATTC

Downstream 100 bases:

>100_bases
CCGTCTGCTGGGGGAAACCATGGCGCGGCATCAGGAGACGGCATTGCGTATTTGCGGCCTGTCGTTCGAAGCCCGAGGCT
GCGTGAGCAGCCAATATCGG

Product: short-chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTQENTKHGKLAGKTMIVVGGARGIGAAIVEALARQEVKVSIFDTDRAPTATNHYQSRDISGYQAACQLAEKLAAQGLSV
QAMAVDATAESQVVEAVDLVAHAAEDFYGLVNAIGSSHVANTVDSSLSEFEAILQTNLTAPYLTSREAARILVRQGRGGA
ILNISSIAAKLAFPGISAYCAAKSGLQGFSGALALELAPHNVRVNCVCPGIVKTNMWKYLENQLMGPGENLEQLWARMEG
LIPLGRTQTAANIARFCVAILENEDITAQSLSVDGGMNLYG

Sequences:

>Translated_281_residues
MTQENTKHGKLAGKTMIVVGGARGIGAAIVEALARQEVKVSIFDTDRAPTATNHYQSRDISGYQAACQLAEKLAAQGLSV
QAMAVDATAESQVVEAVDLVAHAAEDFYGLVNAIGSSHVANTVDSSLSEFEAILQTNLTAPYLTSREAARILVRQGRGGA
ILNISSIAAKLAFPGISAYCAAKSGLQGFSGALALELAPHNVRVNCVCPGIVKTNMWKYLENQLMGPGENLEQLWARMEG
LIPLGRTQTAANIARFCVAILENEDITAQSLSVDGGMNLYG
>Mature_280_residues
TQENTKHGKLAGKTMIVVGGARGIGAAIVEALARQEVKVSIFDTDRAPTATNHYQSRDISGYQAACQLAEKLAAQGLSVQ
AMAVDATAESQVVEAVDLVAHAAEDFYGLVNAIGSSHVANTVDSSLSEFEAILQTNLTAPYLTSREAARILVRQGRGGAI
LNISSIAAKLAFPGISAYCAAKSGLQGFSGALALELAPHNVRVNCVCPGIVKTNMWKYLENQLMGPGENLEQLWARMEGL
IPLGRTQTAANIARFCVAILENEDITAQSLSVDGGMNLYG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=266, Percent_Identity=32.3308270676692, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI32483357, Length=278, Percent_Identity=29.8561151079137, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=29.9212598425197, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=224, Percent_Identity=31.6964285714286, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI15277342, Length=287, Percent_Identity=26.8292682926829, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=279, Percent_Identity=27.9569892473118, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI31542939, Length=220, Percent_Identity=30.4545454545455, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI126723191, Length=204, Percent_Identity=28.4313725490196, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI7705925, Length=270, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=276, Percent_Identity=25.7246376811594, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI126723750, Length=63, Percent_Identity=44.4444444444444, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787335, Length=270, Percent_Identity=32.5925925925926, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788459, Length=172, Percent_Identity=36.046511627907, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367175, Length=266, Percent_Identity=29.6992481203008, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87082160, Length=211, Percent_Identity=31.7535545023697, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI2367365, Length=208, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=279, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082100, Length=274, Percent_Identity=25.1824817518248, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789057, Length=279, Percent_Identity=26.8817204301075, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790717, Length=210, Percent_Identity=27.1428571428571, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789208, Length=172, Percent_Identity=29.0697674418605, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=276, Percent_Identity=28.9855072463768, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=275, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=266, Percent_Identity=25.5639097744361, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=285, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=288, Percent_Identity=26.3888888888889, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=167, Percent_Identity=28.7425149700599, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=277, Percent_Identity=27.7978339350181, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=283, Percent_Identity=27.9151943462898, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=285, Percent_Identity=27.0175438596491, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=271, Percent_Identity=25.0922509225092, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=281, Percent_Identity=25.2669039145907, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=283, Percent_Identity=26.8551236749117, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=269, Percent_Identity=28.996282527881, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21355319, Length=272, Percent_Identity=28.6764705882353, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644339, Length=269, Percent_Identity=28.6245353159851, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=148, Percent_Identity=35.1351351351351, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24643142, Length=206, Percent_Identity=29.6116504854369, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357041, Length=207, Percent_Identity=28.9855072463768, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639444, Length=278, Percent_Identity=25.8992805755396, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17737361, Length=279, Percent_Identity=25.089605734767, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 29621; Mature: 29490

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQENTKHGKLAGKTMIVVGGARGIGAAIVEALARQEVKVSIFDTDRAPTATNHYQSRDI
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCC
SGYQAACQLAEKLAAQGLSVQAMAVDATAESQVVEAVDLVAHAAEDFYGLVNAIGSSHVA
CHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NTVDSSLSEFEAILQTNLTAPYLTSREAARILVRQGRGGAILNISSIAAKLAFPGISAYC
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCHHHHH
AAKSGLQGFSGALALELAPHNVRVNCVCPGIVKTNMWKYLENQLMGPGENLEQLWARMEG
HHHCCCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LIPLGRTQTAANIARFCVAILENEDITAQSLSVDGGMNLYG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
TQENTKHGKLAGKTMIVVGGARGIGAAIVEALARQEVKVSIFDTDRAPTATNHYQSRDI
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCC
SGYQAACQLAEKLAAQGLSVQAMAVDATAESQVVEAVDLVAHAAEDFYGLVNAIGSSHVA
CHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NTVDSSLSEFEAILQTNLTAPYLTSREAARILVRQGRGGAILNISSIAAKLAFPGISAYC
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCHHHHH
AAKSGLQGFSGALALELAPHNVRVNCVCPGIVKTNMWKYLENQLMGPGENLEQLWARMEG
HHHCCCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LIPLGRTQTAANIARFCVAILENEDITAQSLSVDGGMNLYG
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]