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The map label for this gene is tktB [C]

Identifier: 34497712

GI number: 34497712

Start: 2446018

End: 2447685

Strand: Direct

Name: tktB [C]

Synonym: CV_2257

Alternate gene names: 34497712

Gene position: 2446018-2447685 (Clockwise)

Preceding gene: 34497711

Following gene: 34497713

Centisome position: 51.48

GC content: 61.51

Gene sequence:

>1668_bases
CTGAGCGATAGCGAGTATGCGCGTGCGCAGGAAGAAATCGAGGCTGGCCTGGCATTGGCAGATGCGTGCGAGGGCATCAA
TGCGCTGGCGGTGGCCATCGCCGGCCGCTTCGAGCCTTTCTATCGTGACGCGCGCTCATGCCTGGAACGCATACACGAGA
TCGCCGGCTACGGCACGCTGGCGTCTTGCCTGTCGTCGCTGGATATCGCCGAGGCGCTTTTCAGCGCCGGACTTTGCGAT
GCGGCCGGCGTCGCGTCGGAGAATCTGGTGGTAGGGCGGGGCCATATCGCTCCCTTGTTTTATGCTTGCCGGCACCTGAG
GCGGGGCATGCCGCTTGCTTTTCTCGCCGCGGTGCACGATAGGGTCCCGGCCGTGGTGAACAAGACCTATGGTTTCCCCT
ACGGCATGCGCCATAGCCTGGGTGAGGGGATGGGCATCGCGCTCGGCCGCGCCAAAACCCATAGCGATCAGCGAGTGGTA
TGCGTCGCCGGCGATGGTGAATTGAACGAGGGTGTGTCTTACGAGGCCATCCGGCTAGTTGGCGAGCTGGGCATGCGCAA
CCTGACGCTGATCGTGGACAGCAACGGAAAGGGCATCGACCCCCTGCCGGGCACGCTCAGGCCCGCTTATCTAGCCGCCT
ATTTCGATCGGGTGCGCGAGGTTGATGGCCATGACGCGGACGCCATAGTCGAGAGCATGCGAGACGCGGAGCGCGAGGGC
GTGGCAGTCGCCATTATCTGTCATACCCGCAAGGGCTCCCACTCCTTCAAACGCGCAAACGCCAGGCCAGCCATCTCCGC
GACTGCCAAGGCCAGCAGCTGCAGCCTGACGGGAGCGTTGATCGAGGAGATGCGTGAAGGCGGCCCTGCCCATATCTTCA
CCGCGGATCTGGCCGCGCGTTTCGGGCTCCAGCCATCACACGGCTACTGCAATGTCGGTCTTGCGGAGTCCGCTCTGCTG
ACGGCCGCCATGGGCTGCCCGCAGGACGAGCTCAAATTCGTTTTGACCGACGATAAATATTATTTGAATGCAATCGATGT
GCTGCATTCCGCCTTGATCGCCTGCCGCAATCTGCATGTGATAGCCGCGCGAAAAAACGGGGTATGGGGCGGTCCCACCT
ATGTTCAGAGCGTCTTCGGCTTATTGTTTGACGATGCGGTGTATGAGTTTGCGGACCCTCGCGACCTGCAGGCATGCATC
AGGCGGCGGCGGGCGTCGGGAAGCAACGGTCTGTATCTATTGCACGACCAGCCGATGGAGCACGTGCTGGCGATGAGGGA
GAAGTACCGCAGGCTTTCCGACGATGTTTACGCCCATCAGCTCGAACATGCGGGGGGCACGGTGGTCCTGTCTTCGGAGT
CAATGGCATACGAGGCTTTCCTGGCGGTGGACGGCAAGCGCTGCGCGCATGTCCGGGTGTTGTCAACCAGACCGGATCTG
GAGTGTGTGCGCAAGCTGTTGTCGGCTGCGGAGAATGTCGTTGTGGTGGAGCACAACGGTCCCCGTTTCAACCTGGCGGA
ATATGTCGAGTCCACGCTGCTCATCAGGGTCAAAAAGATATGCAGCGATGCCTATGAGTGGCCACGGATAGAGACTTTTC
AAGCCGCAGCCGCGCCCCGCAAGCTGCGCGCCTTGTTGACAGAGCCTTCTTGCGCTTTAGCCGGCTAG

Upstream 100 bases:

>100_bases
GTGCTGAATGAATCGATTAATCACTTGTAAGTCCCCGGTGGATAGCCTGTCAGCACAGCTTTTCGGCATAGACGCCTGCC
TGCGGGGACGGCGCTCAGCT

Downstream 100 bases:

>100_bases
TCGCCTCGACTTCGCGCTCCGCTTTCCCTTTTCATTGTTTTCCGAATCCCGACAGGGCTTCGGCCACCCTTCTATTAACC
GAGGAGTGATGATTCATGAC

Product: hypothetical protein

Products: D-Fructose 6-phosphate; Glyceraldehyde 3-phosphate [C]

Alternate protein names: Transketolase N-Terminal Subunit; Transketolase Domain-Containing Protein; Transketolase N Terminal Section; Transketolase Central Region; Transketolase Domain Protein; Transketolase N- Subunit; Transketolase N Terminal Half; Transaldolase; LigA Protein; Transketolase Subunit A; Transketolase-Like Protein; Transketolase N-Terminal Section

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSDSEYARAQEEIEAGLALADACEGINALAVAIAGRFEPFYRDARSCLERIHEIAGYGTLASCLSSLDIAEALFSAGLCD
AAGVASENLVVGRGHIAPLFYACRHLRRGMPLAFLAAVHDRVPAVVNKTYGFPYGMRHSLGEGMGIALGRAKTHSDQRVV
CVAGDGELNEGVSYEAIRLVGELGMRNLTLIVDSNGKGIDPLPGTLRPAYLAAYFDRVREVDGHDADAIVESMRDAEREG
VAVAIICHTRKGSHSFKRANARPAISATAKASSCSLTGALIEEMREGGPAHIFTADLAARFGLQPSHGYCNVGLAESALL
TAAMGCPQDELKFVLTDDKYYLNAIDVLHSALIACRNLHVIAARKNGVWGGPTYVQSVFGLLFDDAVYEFADPRDLQACI
RRRRASGSNGLYLLHDQPMEHVLAMREKYRRLSDDVYAHQLEHAGGTVVLSSESMAYEAFLAVDGKRCAHVRVLSTRPDL
ECVRKLLSAAENVVVVEHNGPRFNLAEYVESTLLIRVKKICSDAYEWPRIETFQAAAAPRKLRALLTEPSCALAG

Sequences:

>Translated_555_residues
MSDSEYARAQEEIEAGLALADACEGINALAVAIAGRFEPFYRDARSCLERIHEIAGYGTLASCLSSLDIAEALFSAGLCD
AAGVASENLVVGRGHIAPLFYACRHLRRGMPLAFLAAVHDRVPAVVNKTYGFPYGMRHSLGEGMGIALGRAKTHSDQRVV
CVAGDGELNEGVSYEAIRLVGELGMRNLTLIVDSNGKGIDPLPGTLRPAYLAAYFDRVREVDGHDADAIVESMRDAEREG
VAVAIICHTRKGSHSFKRANARPAISATAKASSCSLTGALIEEMREGGPAHIFTADLAARFGLQPSHGYCNVGLAESALL
TAAMGCPQDELKFVLTDDKYYLNAIDVLHSALIACRNLHVIAARKNGVWGGPTYVQSVFGLLFDDAVYEFADPRDLQACI
RRRRASGSNGLYLLHDQPMEHVLAMREKYRRLSDDVYAHQLEHAGGTVVLSSESMAYEAFLAVDGKRCAHVRVLSTRPDL
ECVRKLLSAAENVVVVEHNGPRFNLAEYVESTLLIRVKKICSDAYEWPRIETFQAAAAPRKLRALLTEPSCALAG
>Mature_554_residues
SDSEYARAQEEIEAGLALADACEGINALAVAIAGRFEPFYRDARSCLERIHEIAGYGTLASCLSSLDIAEALFSAGLCDA
AGVASENLVVGRGHIAPLFYACRHLRRGMPLAFLAAVHDRVPAVVNKTYGFPYGMRHSLGEGMGIALGRAKTHSDQRVVC
VAGDGELNEGVSYEAIRLVGELGMRNLTLIVDSNGKGIDPLPGTLRPAYLAAYFDRVREVDGHDADAIVESMRDAEREGV
AVAIICHTRKGSHSFKRANARPAISATAKASSCSLTGALIEEMREGGPAHIFTADLAARFGLQPSHGYCNVGLAESALLT
AAMGCPQDELKFVLTDDKYYLNAIDVLHSALIACRNLHVIAARKNGVWGGPTYVQSVFGLLFDDAVYEFADPRDLQACIR
RRRASGSNGLYLLHDQPMEHVLAMREKYRRLSDDVYAHQLEHAGGTVVLSSESMAYEAFLAVDGKRCAHVRVLSTRPDLE
CVRKLLSAAENVVVVEHNGPRFNLAEYVESTLLIRVKKICSDAYEWPRIETFQAAAAPRKLRALLTEPSCALAG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI133778974, Length=227, Percent_Identity=28.6343612334802, Blast_Score=67, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.2.1.1 [C]

Molecular weight: Translated: 60135; Mature: 60004

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSEYARAQEEIEAGLALADACEGINALAVAIAGRFEPFYRDARSCLERIHEIAGYGTL
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
ASCLSSLDIAEALFSAGLCDAAGVASENLVVGRGHIAPLFYACRHLRRGMPLAFLAAVHD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHH
RVPAVVNKTYGFPYGMRHSLGEGMGIALGRAKTHSDQRVVCVAGDGELNEGVSYEAIRLV
HCHHHHHHCCCCCCCCHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
GELGMRNLTLIVDSNGKGIDPLPGTLRPAYLAAYFDRVREVDGHDADAIVESMRDAEREG
HHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
VAVAIICHTRKGSHSFKRANARPAISATAKASSCSLTGALIEEMREGGPAHIFTADLAAR
CEEEEEEECCCCCCHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHH
FGLQPSHGYCNVGLAESALLTAAMGCPQDELKFVLTDDKYYLNAIDVLHSALIACRNLHV
HCCCCCCCEEECCHHHHHHHHHHHCCCHHHCEEEEECCCHHHHHHHHHHHHHHHHCCEEE
IAARKNGVWGGPTYVQSVFGLLFDDAVYEFADPRDLQACIRRRRASGSNGLYLLHDQPME
EEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHH
HVLAMREKYRRLSDDVYAHQLEHAGGTVVLSSESMAYEAFLAVDGKRCAHVRVLSTRPDL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCEEEEEEECCCCCH
ECVRKLLSAAENVVVVEHNGPRFNLAEYVESTLLIRVKKICSDAYEWPRIETFQAAAAPR
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHH
KLRALLTEPSCALAG
HHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDSEYARAQEEIEAGLALADACEGINALAVAIAGRFEPFYRDARSCLERIHEIAGYGTL
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
ASCLSSLDIAEALFSAGLCDAAGVASENLVVGRGHIAPLFYACRHLRRGMPLAFLAAVHD
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHH
RVPAVVNKTYGFPYGMRHSLGEGMGIALGRAKTHSDQRVVCVAGDGELNEGVSYEAIRLV
HCHHHHHHCCCCCCCCHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHH
GELGMRNLTLIVDSNGKGIDPLPGTLRPAYLAAYFDRVREVDGHDADAIVESMRDAEREG
HHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
VAVAIICHTRKGSHSFKRANARPAISATAKASSCSLTGALIEEMREGGPAHIFTADLAAR
CEEEEEEECCCCCCHHHHCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHH
FGLQPSHGYCNVGLAESALLTAAMGCPQDELKFVLTDDKYYLNAIDVLHSALIACRNLHV
HCCCCCCCEEECCHHHHHHHHHHHCCCHHHCEEEEECCCHHHHHHHHHHHHHHHHCCEEE
IAARKNGVWGGPTYVQSVFGLLFDDAVYEFADPRDLQACIRRRRASGSNGLYLLHDQPME
EEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHH
HVLAMREKYRRLSDDVYAHQLEHAGGTVVLSSESMAYEAFLAVDGKRCAHVRVLSTRPDL
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCEEEEEEECCCCCH
ECVRKLLSAAENVVVVEHNGPRFNLAEYVESTLLIRVKKICSDAYEWPRIETFQAAAAPR
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCHH
KLRALLTEPSCALAG
HHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Thiamine diphosphate, mono-or triphosphate [C]

Metal ions: Mg2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Erythrose 4-phosphate; D-Xylulose 5-phosphate [C]

Specific reaction: D-Erythrose 4-phosphate + D-Xylulose 5-phosphate <==> D-Fructose 6-phosphate + Glyceraldehyde 3-phosphate [C]

General reaction: Keto group transfer [C]

Inhibitor: EDTA; Oxythiamine diphosphate; Phosphate; Rabbit Antibodies; Sulfate [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA