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The map label for this gene is yaeL [C]

Identifier: 34497658

GI number: 34497658

Start: 2373320

End: 2374663

Strand: Direct

Name: yaeL [C]

Synonym: CV_2203

Alternate gene names: 34497658

Gene position: 2373320-2374663 (Clockwise)

Preceding gene: 34497657

Following gene: 34497659

Centisome position: 49.95

GC content: 64.58

Gene sequence:

>1344_bases
ATGCTGACGCTGCTGGCGTTCCTGGTGGCCATCGGCCTGCTGGTGACCTTTCACGAATTGGGCCACTACTGGGTGGCCAA
GCTGTGCGGCGTGAAAGTGCAGCGCTTCTCCATCGGTTTCGGTTCGCCCTTGCTGCGTTTCAGGCCGCGGGAAACCGAGT
GGGTGGTGTGTCCGATTCCGCTCGGCGGCTATGTGAAAATGCTGGACGAACGCGAGGGCTTCGTCGATCCGGCGGAGCGT
CCCAGGGCTTTCAACAACCAGCACGTGCTCAAGCGCATGGCCATCGTTTCCGCCGGACCGCTGGCCAATCTGCTGCTGGC
GGCGCTGCTGTACTGGGCGGTGATCGCCCAGGGCGTGCCCCAGCTGCGTCCGCTGGTCGGGACCGTGGTCGAGCAGACGC
CGGCCGCCGCCGCCGGTTTCAAGGAAGGAGACCTCATCCTCGCCGTGGCGGGGCAAAAGGTTTCCAGCTGGCAAGAGGTG
CGGCTCAATATCGTGGAGGCGGCGATGTCGTCCCCCGCAGTGCCGGTCGAGGTCCAGGAGGCTTCCGGCGCCAGAAAGCG
GCGCGACATCGACGCGCGCCGTTTCGGCGACAAGGCCGAGCAGGCGCTGCAGCAGGGCGATCCCGGTTTGTCGCCGGCGC
GTTTCCTGTTGCAGGTCGGCGCGCTGGAGGAAAAGGGGCCCGCGGCGAAAGCCGGCTTCAAGGTCGGCGACAAGCTGCAG
GCGGTGAACGGCGTCATGCTCAGGAACTGGGAGGAGTGGGTTCACTTGGTCCGGAATAGCCCGGGCAAGGAGCTGACGGT
GCGCGTCGAGCGCGGCGGCAAGCCGCTGGACATCAAGCTGCGGCCGCAGGCCGTCACCCAGGAGGACGAAGTGGTCGGCC
GCATCGGCGTGGGGCCGTTGCCTGACCGGTCCTGGAGCGACAGGCTCGCCTTCACCCAGCATTACGACGCCGCCGGCGCT
TTCGCCGCCGGCTGGGCCAAGACCGGCGAAACGGCTTGGATGAGCGTCAAGTTTCTCGGCAACATGCTGATAGGGCGCGC
TTCGCTGAACAACCTGTCTGGCCCGTTGACGATCGCCAACGTGGCCGGCCAGACCGCTCGGGAGGGGCTGGCCGCCTATC
TGGAATTCCTGGCCCTGATCAGTGTCAGCATAGGGGTGCTCAATCTGCTGCCCATACCGGTTCTGGATGGGGGCCACTTA
ATGTATTATGTCGCGGAGCTGGTCAGAGGTAAGCCCGTCAGCGAGCGGGCGCAATTGCTCGGACAAAAAATTGGTTTCAT
ATTGCTGGCGTCTTTGATGGCTTTTGCCATGCTGAACGATTTCAGCCGCCTATTTGGGGGTTAA

Upstream 100 bases:

>100_bases
CCTCGCTGAGCGGCGTATCCTGCGCCGCCAGCGACAGCCTTGAGGGTTTGCTGGCTCGGGACGAAGAGGCGCGGCGCTTC
GCCGAGGGCGGGGTGGCTGC

Downstream 100 bases:

>100_bases
AACAAACCTATGAAATTGAAGCGACTCGCAGTAGCCGCAATGGGCCTGACCATGGCCACCGTTGCCATGGCTGCAGATCC
GTTTGTGATCAAGGATATCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLTLLAFLVAIGLLVTFHELGHYWVAKLCGVKVQRFSIGFGSPLLRFRPRETEWVVCPIPLGGYVKMLDEREGFVDPAER
PRAFNNQHVLKRMAIVSAGPLANLLLAALLYWAVIAQGVPQLRPLVGTVVEQTPAAAAGFKEGDLILAVAGQKVSSWQEV
RLNIVEAAMSSPAVPVEVQEASGARKRRDIDARRFGDKAEQALQQGDPGLSPARFLLQVGALEEKGPAAKAGFKVGDKLQ
AVNGVMLRNWEEWVHLVRNSPGKELTVRVERGGKPLDIKLRPQAVTQEDEVVGRIGVGPLPDRSWSDRLAFTQHYDAAGA
FAAGWAKTGETAWMSVKFLGNMLIGRASLNNLSGPLTIANVAGQTAREGLAAYLEFLALISVSIGVLNLLPIPVLDGGHL
MYYVAELVRGKPVSERAQLLGQKIGFILLASLMAFAMLNDFSRLFGG

Sequences:

>Translated_447_residues
MLTLLAFLVAIGLLVTFHELGHYWVAKLCGVKVQRFSIGFGSPLLRFRPRETEWVVCPIPLGGYVKMLDEREGFVDPAER
PRAFNNQHVLKRMAIVSAGPLANLLLAALLYWAVIAQGVPQLRPLVGTVVEQTPAAAAGFKEGDLILAVAGQKVSSWQEV
RLNIVEAAMSSPAVPVEVQEASGARKRRDIDARRFGDKAEQALQQGDPGLSPARFLLQVGALEEKGPAAKAGFKVGDKLQ
AVNGVMLRNWEEWVHLVRNSPGKELTVRVERGGKPLDIKLRPQAVTQEDEVVGRIGVGPLPDRSWSDRLAFTQHYDAAGA
FAAGWAKTGETAWMSVKFLGNMLIGRASLNNLSGPLTIANVAGQTAREGLAAYLEFLALISVSIGVLNLLPIPVLDGGHL
MYYVAELVRGKPVSERAQLLGQKIGFILLASLMAFAMLNDFSRLFGG
>Mature_447_residues
MLTLLAFLVAIGLLVTFHELGHYWVAKLCGVKVQRFSIGFGSPLLRFRPRETEWVVCPIPLGGYVKMLDEREGFVDPAER
PRAFNNQHVLKRMAIVSAGPLANLLLAALLYWAVIAQGVPQLRPLVGTVVEQTPAAAAGFKEGDLILAVAGQKVSSWQEV
RLNIVEAAMSSPAVPVEVQEASGARKRRDIDARRFGDKAEQALQQGDPGLSPARFLLQVGALEEKGPAAKAGFKVGDKLQ
AVNGVMLRNWEEWVHLVRNSPGKELTVRVERGGKPLDIKLRPQAVTQEDEVVGRIGVGPLPDRSWSDRLAFTQHYDAAGA
FAAGWAKTGETAWMSVKFLGNMLIGRASLNNLSGPLTIANVAGQTAREGLAAYLEFLALISVSIGVLNLLPIPVLDGGHL
MYYVAELVRGKPVSERAQLLGQKIGFILLASLMAFAMLNDFSRLFGG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=450, Percent_Identity=41.5555555555556, Blast_Score=315, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48423; Mature: 48423

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLLAFLVAIGLLVTFHELGHYWVAKLCGVKVQRFSIGFGSPLLRFRPRETEWVVCPIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHEECCCCCCEEEEECC
LGGYVKMLDEREGFVDPAERPRAFNNQHVLKRMAIVSAGPLANLLLAALLYWAVIAQGVP
CCHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
QLRPLVGTVVEQTPAAAAGFKEGDLILAVAGQKVSSWQEVRLNIVEAAMSSPAVPVEVQE
HHHHHHHHHHHCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECC
ASGARKRRDIDARRFGDKAEQALQQGDPGLSPARFLLQVGALEEKGPAAKAGFKVGDKLQ
CCCCHHHHCCHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AVNGVMLRNWEEWVHLVRNSPGKELTVRVERGGKPLDIKLRPQAVTQEDEVVGRIGVGPL
HHHHHHHHCHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHEECCCCCC
PDRSWSDRLAFTQHYDAAGAFAAGWAKTGETAWMSVKFLGNMLIGRASLNNLSGPLTIAN
CCCCCCCCHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHH
VAGQTAREGLAAYLEFLALISVSIGVLNLLPIPVLDGGHLMYYVAELVRGKPVSERAQLL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCHHHHHHHH
GQKIGFILLASLMAFAMLNDFSRLFGG
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTLLAFLVAIGLLVTFHELGHYWVAKLCGVKVQRFSIGFGSPLLRFRPRETEWVVCPIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHEECCCCCCEEEEECC
LGGYVKMLDEREGFVDPAERPRAFNNQHVLKRMAIVSAGPLANLLLAALLYWAVIAQGVP
CCHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
QLRPLVGTVVEQTPAAAAGFKEGDLILAVAGQKVSSWQEVRLNIVEAAMSSPAVPVEVQE
HHHHHHHHHHHCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEECC
ASGARKRRDIDARRFGDKAEQALQQGDPGLSPARFLLQVGALEEKGPAAKAGFKVGDKLQ
CCCCHHHHCCHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AVNGVMLRNWEEWVHLVRNSPGKELTVRVERGGKPLDIKLRPQAVTQEDEVVGRIGVGPL
HHHHHHHHCHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHEECCCCCC
PDRSWSDRLAFTQHYDAAGAFAAGWAKTGETAWMSVKFLGNMLIGRASLNNLSGPLTIAN
CCCCCCCCHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHH
VAGQTAREGLAAYLEFLALISVSIGVLNLLPIPVLDGGHLMYYVAELVRGKPVSERAQLL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCHHHHHHHH
GQKIGFILLASLMAFAMLNDFSRLFGG
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]