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The map label for this gene is cysC [H]

Identifier: 34497559

GI number: 34497559

Start: 2296282

End: 2296941

Strand: Direct

Name: cysC [H]

Synonym: CV_2104

Alternate gene names: 34497559

Gene position: 2296282-2296941 (Clockwise)

Preceding gene: 34497558

Following gene: 34497560

Centisome position: 48.33

GC content: 66.06

Gene sequence:

>660_bases
ATGGGCGAGGTTTCCATTCAGGCGGGCGTGCCCGCCAATGTTTTTCGCACCGGAGGGCGGATCCGCCTGGTGGACCGGCA
GCGGCTTTTCGGCCATGCGGCGGTGACCATCTGGCTGACCGGGCTGAGCGGCGCGGGCAAGTCCACCATCGCCTATGAAC
TGGAGGCGAGGCTGGTGCGCGGCGGTTTCTCCGCCGTGGTGCTGGACGGGGACAATCTGCGCCACGGCATCAACCGCAAC
CTGGGTTTCACCGATGCCGACCGCCGGGAAAATCTGCGCCGGGTGGCCGAGGTGGCGAGGCTGATGAACGATGCCGGGCT
GATCGTGATCTGTTCCTGCATTTCTCCGCTGCGCATCGACCGCGAAATGGCGCGCGACATCGTCGGCGAACGCCATTTCG
CCGAGGTTTACGTCAGCACGCCGCTGGCGGTGTGCGAGCAGCGCGATTGCAAGGGTCTGTACGCGAAGGCGCGCTCGGGA
CAGATCGCCCATTTCACCGGCGTGTCCTCGCCGTACGAAGCGCCCGAGCAGGCCGCGCTGGCGCTGGACACCAGCGCGCT
GAGCGTGGATGAATGCGTGGACAGGCTGTTCGGCATGGTGCTGCGCTGTTGCAGCCCGGCGGCGATGGAGGGAGGCATCG
GCCATGAATACCATATCTGA

Upstream 100 bases:

>100_bases
CCTCTGTTAGGCGCTATGACCAGATTGTCCGGATATGTGATTGCCGCGGCGCCGGGGGTTCCCTTGGGCGCGCGAGCGCG
ATCACCGGGGAGGGCGGCAG

Downstream 100 bases:

>100_bases
GGAAAGCCGGCCTGTGCCGGCGCTGATGATTCCGCTGCGGCGCTGCGGCAGCCACGCGCTGAGGCTTCGGCTCAATTTCA
ATACCGACTTCTATTCGCCG

Product: adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MGEVSIQAGVPANVFRTGGRIRLVDRQRLFGHAAVTIWLTGLSGAGKSTIAYELEARLVRGGFSAVVLDGDNLRHGINRN
LGFTDADRRENLRRVAEVARLMNDAGLIVICSCISPLRIDREMARDIVGERHFAEVYVSTPLAVCEQRDCKGLYAKARSG
QIAHFTGVSSPYEAPEQAALALDTSALSVDECVDRLFGMVLRCCSPAAMEGGIGHEYHI

Sequences:

>Translated_219_residues
MGEVSIQAGVPANVFRTGGRIRLVDRQRLFGHAAVTIWLTGLSGAGKSTIAYELEARLVRGGFSAVVLDGDNLRHGINRN
LGFTDADRRENLRRVAEVARLMNDAGLIVICSCISPLRIDREMARDIVGERHFAEVYVSTPLAVCEQRDCKGLYAKARSG
QIAHFTGVSSPYEAPEQAALALDTSALSVDECVDRLFGMVLRCCSPAAMEGGIGHEYHI
>Mature_218_residues
GEVSIQAGVPANVFRTGGRIRLVDRQRLFGHAAVTIWLTGLSGAGKSTIAYELEARLVRGGFSAVVLDGDNLRHGINRNL
GFTDADRRENLRRVAEVARLMNDAGLIVICSCISPLRIDREMARDIVGERHFAEVYVSTPLAVCEQRDCKGLYAKARSGQ
IAHFTGVSSPYEAPEQAALALDTSALSVDECVDRLFGMVLRCCSPAAMEGGIGHEYHI

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=172, Percent_Identity=52.3255813953488, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI34447231, Length=172, Percent_Identity=51.1627906976744, Blast_Score=177, Evalue=6e-45,
Organism=Homo sapiens, GI62912492, Length=172, Percent_Identity=51.1627906976744, Blast_Score=177, Evalue=7e-45,
Organism=Escherichia coli, GI1789107, Length=188, Percent_Identity=51.063829787234, Blast_Score=188, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17542422, Length=169, Percent_Identity=52.6627218934911, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6322852, Length=179, Percent_Identity=49.1620111731844, Blast_Score=177, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24667032, Length=172, Percent_Identity=53.4883720930233, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667028, Length=172, Percent_Identity=53.4883720930233, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667036, Length=172, Percent_Identity=53.4883720930233, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI116007838, Length=172, Percent_Identity=53.4883720930233, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667044, Length=172, Percent_Identity=53.4883720930233, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667040, Length=172, Percent_Identity=53.4883720930233, Blast_Score=187, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 23760; Mature: 23628

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVSIQAGVPANVFRTGGRIRLVDRQRLFGHAAVTIWLTGLSGAGKSTIAYELEARLVR
CCCEEEECCCCHHHHHCCCEEEEEEHHHHHHHEEEEEEEECCCCCCCCEEEHHHHHHHHH
GGFSAVVLDGDNLRHGINRNLGFTDADRRENLRRVAEVARLMNDAGLIVICSCISPLRID
CCCEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
REMARDIVGERHFAEVYVSTPLAVCEQRDCKGLYAKARSGQIAHFTGVSSPYEAPEQAAL
HHHHHHHHCCHHHHHEEECCHHHHHCCCCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHE
ALDTSALSVDECVDRLFGMVLRCCSPAAMEGGIGHEYHI
EECCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
GEVSIQAGVPANVFRTGGRIRLVDRQRLFGHAAVTIWLTGLSGAGKSTIAYELEARLVR
CCEEEECCCCHHHHHCCCEEEEEEHHHHHHHEEEEEEEECCCCCCCCEEEHHHHHHHHH
GGFSAVVLDGDNLRHGINRNLGFTDADRRENLRRVAEVARLMNDAGLIVICSCISPLRID
CCCEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
REMARDIVGERHFAEVYVSTPLAVCEQRDCKGLYAKARSGQIAHFTGVSSPYEAPEQAAL
HHHHHHHHCCHHHHHEEECCHHHHHCCCCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHE
ALDTSALSVDECVDRLFGMVLRCCSPAAMEGGIGHEYHI
EECCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]