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The map label for this gene is paaG [H]

Identifier: 34497537

GI number: 34497537

Start: 2267659

End: 2268768

Strand: Reverse

Name: paaG [H]

Synonym: CV_2082

Alternate gene names: 34497537

Gene position: 2268768-2267659 (Counterclockwise)

Preceding gene: 34497538

Following gene: 34497536

Centisome position: 47.75

GC content: 69.01

Gene sequence:

>1110_bases
GTGGTGCTGTTTGACGAACTGACTACCGGCGACGGCCATCGCATCGCCGTCGCCACCCTCAACGCCGAGAAATCGCTGAA
CGCGCTGACGCTGGACATGATCCGGCTGCTGGACGCCCGCCTCACCATCTGGGAGCGCGACGAAGGCATCGTCGCCGTGG
TGCTGCGCGGCGCCGGCGAGCGCGCCTTCTGCGCCGGCGGCGACGTGCGCGGCCTGCGAGAAAAGCTGGTCAGCGAGCCG
CACTACCCGCATCCGCACGCCGTGGCCTTCTTCACCGAGGAATACACGCTCGACTACCGCATCCACCGTTACCCAAAGCC
GCTGATCGTGTGGGGCGGCGGCATCGTGATGGGCGGCGGCCTGGGCCTGATGGCCGGCGCCAGCCACCGCGTGGTCACGC
CCGCCACCCGCATCGCGATGCCGGAAATCACCATCGGCCTGTACCCGGACGTGGGCGGCAGCTGGTTCCTGCAGCGCATG
CCTGCGCACCTGGGCCTGTTCCTGGCGCTGACCGGCGCGCCGCTGAACGCCCACGACGCGCTGATCGCCAATCTGGCCGA
CCACGTGCTGGCGGCGGATGCCTACCCGGCGCTGCTGCAGGCCTTGCAGGCGGCAAACTGGGGCCACGACGCCCATGCGC
GCCCGGCCCTGGTCAGCGCCTTGCTGAACCAGCTGGAAAGCCAGCTGGGCGACGCGCTGCCGGCGTCCAACGTCGAACGC
AATCTGCTGGCGGTGCACCGGCTGATGAACAAGGGCGACCTGGCCGCCGTCAGCGCGGCCCTCACCGAAACCGCCTTCGA
AGACCCGTGGCTCTCTGACGCCGCCAAGAACTTTCGCCATGGCTGCCCCACTTCCGCTGCCGTCAGCTGGGAAATCCTGG
ACCGCGCCAAGCACATGTCGCTGGCCGAGGCGCTGCGGATGGAACTGGTTCTATCCGTCAACTTCTGCGCCCGCTCCGAC
TTCCCCGAGGGCGTGCGCGCGCTGCTGGTGGACAAGGACCGCAATCCGCGCTGGAGCCGGCAGCTGGCCGACATCGACCA
GGCCTGGGTGGACGGGCATTTCGAATCGCCGTGGCGCGAGGCCGACCACCCGCTGGCGGGATTGAAATAA

Upstream 100 bases:

>100_bases
CAGGCCGAAGGCACCCGCGCCTTCCTGGAAAAGCGCGCGCCGAACTGGAAGAACGCCTGAAACCCGCCCATCACCCGAAC
GAGGTCCCGCCATGCAAGAC

Downstream 100 bases:

>100_bases
CAAGCATACAGAGGAGAACAGCATGGAAAACATCGCCTTCATCGGCCTGGGCAATATGGGCGGGCCGATGGCCGTCAATC
TGCTGAACAAGGGCTTCAAG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MVLFDELTTGDGHRIAVATLNAEKSLNALTLDMIRLLDARLTIWERDEGIVAVVLRGAGERAFCAGGDVRGLREKLVSEP
HYPHPHAVAFFTEEYTLDYRIHRYPKPLIVWGGGIVMGGGLGLMAGASHRVVTPATRIAMPEITIGLYPDVGGSWFLQRM
PAHLGLFLALTGAPLNAHDALIANLADHVLAADAYPALLQALQAANWGHDAHARPALVSALLNQLESQLGDALPASNVER
NLLAVHRLMNKGDLAAVSAALTETAFEDPWLSDAAKNFRHGCPTSAAVSWEILDRAKHMSLAEALRMELVLSVNFCARSD
FPEGVRALLVDKDRNPRWSRQLADIDQAWVDGHFESPWREADHPLAGLK

Sequences:

>Translated_369_residues
MVLFDELTTGDGHRIAVATLNAEKSLNALTLDMIRLLDARLTIWERDEGIVAVVLRGAGERAFCAGGDVRGLREKLVSEP
HYPHPHAVAFFTEEYTLDYRIHRYPKPLIVWGGGIVMGGGLGLMAGASHRVVTPATRIAMPEITIGLYPDVGGSWFLQRM
PAHLGLFLALTGAPLNAHDALIANLADHVLAADAYPALLQALQAANWGHDAHARPALVSALLNQLESQLGDALPASNVER
NLLAVHRLMNKGDLAAVSAALTETAFEDPWLSDAAKNFRHGCPTSAAVSWEILDRAKHMSLAEALRMELVLSVNFCARSD
FPEGVRALLVDKDRNPRWSRQLADIDQAWVDGHFESPWREADHPLAGLK
>Mature_369_residues
MVLFDELTTGDGHRIAVATLNAEKSLNALTLDMIRLLDARLTIWERDEGIVAVVLRGAGERAFCAGGDVRGLREKLVSEP
HYPHPHAVAFFTEEYTLDYRIHRYPKPLIVWGGGIVMGGGLGLMAGASHRVVTPATRIAMPEITIGLYPDVGGSWFLQRM
PAHLGLFLALTGAPLNAHDALIANLADHVLAADAYPALLQALQAANWGHDAHARPALVSALLNQLESQLGDALPASNVER
NLLAVHRLMNKGDLAAVSAALTETAFEDPWLSDAAKNFRHGCPTSAAVSWEILDRAKHMSLAEALRMELVLSVNFCARSD
FPEGVRALLVDKDRNPRWSRQLADIDQAWVDGHFESPWREADHPLAGLK

Specific function: FADb And FADa Are The Alpha And Beta Subunits Of The Multifunctional Enzyme Complex Of The Fatty Acid Degradation Cycle. [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=344, Percent_Identity=34.593023255814, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI37594469, Length=299, Percent_Identity=34.1137123745819, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI194097323, Length=202, Percent_Identity=28.2178217821782, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790281, Length=223, Percent_Identity=26.9058295964126, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=343, Percent_Identity=34.9854227405248, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI25144160, Length=340, Percent_Identity=35.5882352941176, Blast_Score=197, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6320241, Length=362, Percent_Identity=27.6243093922652, Blast_Score=139, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571729, Length=343, Percent_Identity=36.734693877551, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI28571730, Length=343, Percent_Identity=36.734693877551, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI20129971, Length=185, Percent_Identity=30.2702702702703, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653477, Length=185, Percent_Identity=30.2702702702703, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 40228; Mature: 40228

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFDELTTGDGHRIAVATLNAEKSLNALTLDMIRLLDARLTIWERDEGIVAVVLRGAGE
CEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCC
RAFCAGGDVRGLREKLVSEPHYPHPHAVAFFTEEYTLDYRIHRYPKPLIVWGGGIVMGGG
EEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEECEEEEEEEECCCCCEEEECCCEEEECC
LGLMAGASHRVVTPATRIAMPEITIGLYPDVGGSWFLQRMPAHLGLFLALTGAPLNAHDA
CHHHCCCCCCEECCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHH
LIANLADHVLAADAYPALLQALQAANWGHDAHARPALVSALLNQLESQLGDALPASNVER
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
NLLAVHRLMNKGDLAAVSAALTETAFEDPWLSDAAKNFRHGCPTSAAVSWEILDRAKHMS
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
LAEALRMELVLSVNFCARSDFPEGVRALLVDKDRNPRWSRQLADIDQAWVDGHFESPWRE
HHHHHHHHHHEEEEHHHCCCCHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHH
ADHPLAGLK
CCCCCCCCC
>Mature Secondary Structure
MVLFDELTTGDGHRIAVATLNAEKSLNALTLDMIRLLDARLTIWERDEGIVAVVLRGAGE
CEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEEEECCCC
RAFCAGGDVRGLREKLVSEPHYPHPHAVAFFTEEYTLDYRIHRYPKPLIVWGGGIVMGGG
EEEECCCCHHHHHHHHHCCCCCCCCCEEEEEEECEEEEEEEECCCCCEEEECCCEEEECC
LGLMAGASHRVVTPATRIAMPEITIGLYPDVGGSWFLQRMPAHLGLFLALTGAPLNAHDA
CHHHCCCCCCEECCHHHHCCCCEEEEECCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHH
LIANLADHVLAADAYPALLQALQAANWGHDAHARPALVSALLNQLESQLGDALPASNVER
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
NLLAVHRLMNKGDLAAVSAALTETAFEDPWLSDAAKNFRHGCPTSAAVSWEILDRAKHMS
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
LAEALRMELVLSVNFCARSDFPEGVRALLVDKDRNPRWSRQLADIDQAWVDGHFESPWRE
HHHHHHHHHHEEEEHHHCCCCHHHHHEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHH
ADHPLAGLK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]