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The map label for this gene is motA1 [H]

Identifier: 34497481

GI number: 34497481

Start: 2208189

End: 2209043

Strand: Direct

Name: motA1 [H]

Synonym: CV_2026

Alternate gene names: 34497481

Gene position: 2208189-2209043 (Clockwise)

Preceding gene: 34497480

Following gene: 34497482

Centisome position: 46.48

GC content: 62.69

Gene sequence:

>855_bases
ATGTTCGTCGGAATCGGGTATCTCATCATCCTGGGCTCGGTGCTCGGGGGCTTCATCGCCGCAGGGGGGCATGTCGCCGC
GCTGATGCAACCGCTGGAGGTCGTCATGATCGCCGGCGCGGCCATCGGCGCCTTCATCGTCGCCAACGGCGGCGCGCCGC
TGAAAGCCACCACCAAGGCGCTCCCTACCGTGTTCAAGGGCAGCCCTTACGGCAAGGCCTTCTACATGGATCTGTTTTCC
CTGCTGTTCGAGATCCTGACCAAGGTGCGCAAGGAAGGCCTGATGTCGATCGAGGCCGACGTCGAGAATCCCGAAGCCAG
TCCCGTCTTTTCCAAATACCCGACCATCATGCACGACCACCACGTGGTCGAATTCATTTGCGATTACCTGCGGCTGATGG
TGGGCGGCAACCTCAACGCCTTCGAGATCGAGAACCTAATGGACGTCGAGATCGAAACCCACCACCATGAGGGCGAAGTC
CCGGTGTCGGCGGTGAAGGGGCTGGCCGACGGCCTGCCCGCCTTCGGTATCGTGGCGGCGGTGATGGGCGTGGTCCACAC
TATGGAATCGGTGGGCGCGCCGCCGTCGGAGCTAGGCATGCTGATCGCCCACGCGCTGGTGGGCACCTTCCTCGGTATTT
TGCTGGCCTATGGCTTCGTCGGACCGCTGGGCACCATCCTGGAGCACAAGCTGGCGGAAGGCACCCGCGTCTACCAGACC
ATCAAGGTGACGCTGCTGGCCAGCCTGAACGGCTACGCGCCGCAAGTGGCGGTGGAGTTCGGCCGCAAGGCGCTGTCCTC
GATGGACCGTCCGTCGTTCAAGGAACTGGAAGACCACGTCAAGCAGAAGAAATAA

Upstream 100 bases:

>100_bases
TCCACCCGCTTTTTCTATTATTTCTATAATGAATTGCAAAAAGGCATGCTGTAATACAAATAGCGGCATGGGGCAATAAA
ACAAATACAGGACTTGGCGC

Downstream 100 bases:

>100_bases
GCCGGGCAGGGGACAGAAATGGCTGACGAATCGCAACGACCCATAGTCGTCAAGAAAATCAAGAAAGGCGGGCACGGCCA
TCACGGCGGCGCCTGGAAAA

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MFVGIGYLIILGSVLGGFIAAGGHVAALMQPLEVVMIAGAAIGAFIVANGGAPLKATTKALPTVFKGSPYGKAFYMDLFS
LLFEILTKVRKEGLMSIEADVENPEASPVFSKYPTIMHDHHVVEFICDYLRLMVGGNLNAFEIENLMDVEIETHHHEGEV
PVSAVKGLADGLPAFGIVAAVMGVVHTMESVGAPPSELGMLIAHALVGTFLGILLAYGFVGPLGTILEHKLAEGTRVYQT
IKVTLLASLNGYAPQVAVEFGRKALSSMDRPSFKELEDHVKQKK

Sequences:

>Translated_284_residues
MFVGIGYLIILGSVLGGFIAAGGHVAALMQPLEVVMIAGAAIGAFIVANGGAPLKATTKALPTVFKGSPYGKAFYMDLFS
LLFEILTKVRKEGLMSIEADVENPEASPVFSKYPTIMHDHHVVEFICDYLRLMVGGNLNAFEIENLMDVEIETHHHEGEV
PVSAVKGLADGLPAFGIVAAVMGVVHTMESVGAPPSELGMLIAHALVGTFLGILLAYGFVGPLGTILEHKLAEGTRVYQT
IKVTLLASLNGYAPQVAVEFGRKALSSMDRPSFKELEDHVKQKK
>Mature_284_residues
MFVGIGYLIILGSVLGGFIAAGGHVAALMQPLEVVMIAGAAIGAFIVANGGAPLKATTKALPTVFKGSPYGKAFYMDLFS
LLFEILTKVRKEGLMSIEADVENPEASPVFSKYPTIMHDHHVVEFICDYLRLMVGGNLNAFEIENLMDVEIETHHHEGEV
PVSAVKGLADGLPAFGIVAAVMGVVHTMESVGAPPSELGMLIAHALVGTFLGILLAYGFVGPLGTILEHKLAEGTRVYQT
IKVTLLASLNGYAPQVAVEFGRKALSSMDRPSFKELEDHVKQKK

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=57.0422535211268, Blast_Score=342, Evalue=2e-95,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30260; Mature: 30260

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVGIGYLIILGSVLGGFIAAGGHVAALMQPLEVVMIAGAAIGAFIVANGGAPLKATTKA
CEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
LPTVFKGSPYGKAFYMDLFSLLFEILTKVRKEGLMSIEADVENPEASPVFSKYPTIMHDH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHCCHHHHHH
HVVEFICDYLRLMVGGNLNAFEIENLMDVEIETHHHEGEVPVSAVKGLADGLPAFGIVAA
HHHHHHHHHHHHHHCCCCCCEECCCHHEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHH
VMGVVHTMESVGAPPSELGMLIAHALVGTFLGILLAYGFVGPLGTILEHKLAEGTRVYQT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IKVTLLASLNGYAPQVAVEFGRKALSSMDRPSFKELEDHVKQKK
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MFVGIGYLIILGSVLGGFIAAGGHVAALMQPLEVVMIAGAAIGAFIVANGGAPLKATTKA
CEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHH
LPTVFKGSPYGKAFYMDLFSLLFEILTKVRKEGLMSIEADVENPEASPVFSKYPTIMHDH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHCCHHHHHH
HVVEFICDYLRLMVGGNLNAFEIENLMDVEIETHHHEGEVPVSAVKGLADGLPAFGIVAA
HHHHHHHHHHHHHHCCCCCCEECCCHHEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHH
VMGVVHTMESVGAPPSELGMLIAHALVGTFLGILLAYGFVGPLGTILEHKLAEGTRVYQT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
IKVTLLASLNGYAPQVAVEFGRKALSSMDRPSFKELEDHVKQKK
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]