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The map label for this gene is ygjG [C]

Identifier: 34497480

GI number: 34497480

Start: 2206636

End: 2208015

Strand: Direct

Name: ygjG [C]

Synonym: CV_2025

Alternate gene names: 34497480

Gene position: 2206636-2208015 (Clockwise)

Preceding gene: 34497479

Following gene: 34497481

Centisome position: 46.44

GC content: 65.07

Gene sequence:

>1380_bases
ATGCAGAAGCAACGTACGACCAGCCAATGGCGCGAACTGGATGCCGCCCATCACCTGCATCCGTTCACCGATACCGCATC
GCTGAACCAGGCGGGCGCGCGCGTGATGACGCGCGGAGAGGGCGTCTACCTGTGGGATTCGGAAGGCAACAAGATCATCG
ACGGCATGGCCGGACTGTGGTGCGTGAACGTCGGCTACGGCCGCAAGGACTTTGCCGAAGCGGCGCGCCGGCAGATGGAA
GAGCTGCCGTTCTACAACACCTTCTTCAAGACCACCCATCCGGCGGTGGTCGAGCTGTCCAGCCTGCTGGCTGAAGTGAC
GCCGGCCGGTTTCGACCGCGTGTTCTATACCAATTCCGGTTCCGAATCGGTGGACACCATGATCCGCATGGTGCGCCGCT
ACTGGGACGTGCAGGGCAAGCCGGAGAAGAAGACGCTGATCGGCCGCTGGAACGGCTATCACGGCTCCACCATCGGCGGC
GCCAGCCTGGGCGGCATGAAGTACATGCACGAGCAGGGCGACTTGCCGATTCCGGGCATGGCCCACATCGAGCAGCCTTG
GTGGTACAAGCACGGCAAGGACATGACGCCGGACGAGTTCGGCGTGGTGGCCGCGCGCTGGCTGGAAGAGAAGATTCTGG
AAATCGGCGCCGACAAGGTGGCCGCCTTCGTCGGCGAACCCATCCAGGGCGCCGGCGGCGTGATCGTCCCGCCGGCCACC
TACTGGCCGGAAATCGAGCGCATTTGCCGCAAGTACGACGTGCTGCTGGTGGCCGACGAAGTGATCTGCGGCTTCGGGCG
TACCGGCGAATGGTTCGGCCATCAGCATTTCGGCTTCCAGCCCGACCTGTTCACCGCCGCCAAGGGCCTGTCCTCCGGCT
ATCTGCCGATAGGCGCGGTCTTTGTCGGCAAGCGCGTGGCCGAAGGCCTGATCGCCGGCGGCGACTTCAACCACGGCTTC
ACCTACTCCGGCCACCCGGTCTGCGCCGCCGTCGCCCACGCCAACGTGGCGGCGCTGCGCGACGAGGGCATCGTCCAGCG
CGTCAAGGACGACATCGGCCCGTACATGCAAAAGCGCTGGCGTGAAACCTTCAGCCGTTTCGAGCATGTGGACGACGTGC
GCGGCGTCGGCATGGTGCAGGCGTTCACCCTGGTGAAGAACAAGGCGAAGCGCGAGCTGTTCCCCGATTTCGGCGAGATC
GGCACGCTGTGCCGCGACATCTTCTTCCGCAACAACCTGATCATGCGGGCATGCGGCGACCACATCGTGTCGGCGCCGCC
GCTGGTGATGACGCGGGCGGAAGTGGACGAGATGCTGGCGGTGGCGGAACGCTGTCTGGAGGAATTCGAGCAGACGCTGA
AGGCGCGCGGGCTGGCTTAG

Upstream 100 bases:

>100_bases
GAATCGCGGAACAGACAGGACAAACGAATAGAAAGACGCCGCAGGCGCAGGAGGGGCGGGCAAGGGCCCGCCTCGTCGGA
GAAAACTGGAAGGAAGTGTT

Downstream 100 bases:

>100_bases
CGCCGGCTATGCTGGTGTGGGGGGCGGCCTCGCCCCCGCCTTTTTTGCAGGGAATGAAGCGGGTTGATACAATTCCACCC
GCTTTTTCTATTATTTCTAT

Product: aminotransferase

Products: S-adenosyl-4-methylthio-2-oxobutanoate; 7,8-diaminononanoate

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MQKQRTTSQWRELDAAHHLHPFTDTASLNQAGARVMTRGEGVYLWDSEGNKIIDGMAGLWCVNVGYGRKDFAEAARRQME
ELPFYNTFFKTTHPAVVELSSLLAEVTPAGFDRVFYTNSGSESVDTMIRMVRRYWDVQGKPEKKTLIGRWNGYHGSTIGG
ASLGGMKYMHEQGDLPIPGMAHIEQPWWYKHGKDMTPDEFGVVAARWLEEKILEIGADKVAAFVGEPIQGAGGVIVPPAT
YWPEIERICRKYDVLLVADEVICGFGRTGEWFGHQHFGFQPDLFTAAKGLSSGYLPIGAVFVGKRVAEGLIAGGDFNHGF
TYSGHPVCAAVAHANVAALRDEGIVQRVKDDIGPYMQKRWRETFSRFEHVDDVRGVGMVQAFTLVKNKAKRELFPDFGEI
GTLCRDIFFRNNLIMRACGDHIVSAPPLVMTRAEVDEMLAVAERCLEEFEQTLKARGLA

Sequences:

>Translated_459_residues
MQKQRTTSQWRELDAAHHLHPFTDTASLNQAGARVMTRGEGVYLWDSEGNKIIDGMAGLWCVNVGYGRKDFAEAARRQME
ELPFYNTFFKTTHPAVVELSSLLAEVTPAGFDRVFYTNSGSESVDTMIRMVRRYWDVQGKPEKKTLIGRWNGYHGSTIGG
ASLGGMKYMHEQGDLPIPGMAHIEQPWWYKHGKDMTPDEFGVVAARWLEEKILEIGADKVAAFVGEPIQGAGGVIVPPAT
YWPEIERICRKYDVLLVADEVICGFGRTGEWFGHQHFGFQPDLFTAAKGLSSGYLPIGAVFVGKRVAEGLIAGGDFNHGF
TYSGHPVCAAVAHANVAALRDEGIVQRVKDDIGPYMQKRWRETFSRFEHVDDVRGVGMVQAFTLVKNKAKRELFPDFGEI
GTLCRDIFFRNNLIMRACGDHIVSAPPLVMTRAEVDEMLAVAERCLEEFEQTLKARGLA
>Mature_459_residues
MQKQRTTSQWRELDAAHHLHPFTDTASLNQAGARVMTRGEGVYLWDSEGNKIIDGMAGLWCVNVGYGRKDFAEAARRQME
ELPFYNTFFKTTHPAVVELSSLLAEVTPAGFDRVFYTNSGSESVDTMIRMVRRYWDVQGKPEKKTLIGRWNGYHGSTIGG
ASLGGMKYMHEQGDLPIPGMAHIEQPWWYKHGKDMTPDEFGVVAARWLEEKILEIGADKVAAFVGEPIQGAGGVIVPPAT
YWPEIERICRKYDVLLVADEVICGFGRTGEWFGHQHFGFQPDLFTAAKGLSSGYLPIGAVFVGKRVAEGLIAGGDFNHGF
TYSGHPVCAAVAHANVAALRDEGIVQRVKDDIGPYMQKRWRETFSRFEHVDDVRGVGMVQAFTLVKNKAKRELFPDFGEI
GTLCRDIFFRNNLIMRACGDHIVSAPPLVMTRAEVDEMLAVAERCLEEFEQTLKARGLA

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=449, Percent_Identity=26.2806236080178, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=26.7281105990783, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI226442705, Length=450, Percent_Identity=26.6666666666667, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4557809, Length=442, Percent_Identity=26.0180995475113, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI226442709, Length=421, Percent_Identity=26.603325415677, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=25.9770114942529, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI284507298, Length=232, Percent_Identity=31.0344827586207, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI145693181, Length=407, Percent_Identity=27.5184275184275, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1786991, Length=446, Percent_Identity=28.0269058295964, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=28.5012285012285, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1788044, Length=415, Percent_Identity=27.4698795180723, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789016, Length=422, Percent_Identity=25.1184834123223, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787560, Length=419, Percent_Identity=27.2076372315036, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=24.6794871794872, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI25144271, Length=423, Percent_Identity=26.4775413711584, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=443, Percent_Identity=26.6365688487585, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32564660, Length=449, Percent_Identity=26.9487750556793, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=237, Percent_Identity=30.379746835443, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17541228, Length=444, Percent_Identity=22.7477477477477, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323470, Length=453, Percent_Identity=27.3730684326711, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324432, Length=424, Percent_Identity=26.8867924528302, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324386, Length=439, Percent_Identity=26.879271070615, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321456, Length=373, Percent_Identity=23.5924932975871, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356575, Length=429, Percent_Identity=28.4382284382284, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.4784580498866, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574759, Length=439, Percent_Identity=29.8405466970387, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI21357415, Length=440, Percent_Identity=27.0454545454545, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281366494, Length=387, Percent_Identity=21.9638242894057, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667139, Length=387, Percent_Identity=21.9638242894057, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24667143, Length=387, Percent_Identity=21.9638242894057, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.62

Molecular weight: Translated: 51214; Mature: 51214

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKQRTTSQWRELDAAHHLHPFTDTASLNQAGARVMTRGEGVYLWDSEGNKIIDGMAGLW
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEECCCEEEEECCCCCEEHHCCCCEE
CVNVGYGRKDFAEAARRQMEELPFYNTFFKTTHPAVVELSSLLAEVTPAGFDRVFYTNSG
EEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
SESVDTMIRMVRRYWDVQGKPEKKTLIGRWNGYHGSTIGGASLGGMKYMHEQGDLPIPGM
CHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCH
AHIEQPWWYKHGKDMTPDEFGVVAARWLEEKILEIGADKVAAFVGEPIQGAGGVIVPPAT
HHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEECCCC
YWPEIERICRKYDVLLVADEVICGFGRTGEWFGHQHFGFQPDLFTAAKGLSSGYLPIGAV
CCHHHHHHHHHHCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHH
FVGKRVAEGLIAGGDFNHGFTYSGHPVCAAVAHANVAALRDEGIVQRVKDDIGPYMQKRW
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RETFSRFEHVDDVRGVGMVQAFTLVKNKAKRELFPDFGEIGTLCRDIFFRNNLIMRACGD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCC
HIVSAPPLVMTRAEVDEMLAVAERCLEEFEQTLKARGLA
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKQRTTSQWRELDAAHHLHPFTDTASLNQAGARVMTRGEGVYLWDSEGNKIIDGMAGLW
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCEEECCCEEEEECCCCCEEHHCCCCEE
CVNVGYGRKDFAEAARRQMEELPFYNTFFKTTHPAVVELSSLLAEVTPAGFDRVFYTNSG
EEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEECCC
SESVDTMIRMVRRYWDVQGKPEKKTLIGRWNGYHGSTIGGASLGGMKYMHEQGDLPIPGM
CHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCH
AHIEQPWWYKHGKDMTPDEFGVVAARWLEEKILEIGADKVAAFVGEPIQGAGGVIVPPAT
HHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCEEECCCC
YWPEIERICRKYDVLLVADEVICGFGRTGEWFGHQHFGFQPDLFTAAKGLSSGYLPIGAV
CCHHHHHHHHHHCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHH
FVGKRVAEGLIAGGDFNHGFTYSGHPVCAAVAHANVAALRDEGIVQRVKDDIGPYMQKRW
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RETFSRFEHVDDVRGVGMVQAFTLVKNKAKRELFPDFGEIGTLCRDIFFRNNLIMRACGD
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCC
HIVSAPPLVMTRAEVDEMLAVAERCLEEFEQTLKARGLA
HHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; 8-amino-7-oxononanoate

Specific reaction: S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]