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The map label for this gene is exbB2 [H]

Identifier: 34497439

GI number: 34497439

Start: 2162577

End: 2163323

Strand: Direct

Name: exbB2 [H]

Synonym: CV_1984

Alternate gene names: 34497439

Gene position: 2162577-2163323 (Clockwise)

Preceding gene: 34497438

Following gene: 34497440

Centisome position: 45.52

GC content: 65.86

Gene sequence:

>747_bases
ATGACCAAGATCACTCGCGCATTTCTGGGCAAAGTCCTGGGCGCAGCCGGCCTGCTGACCGCACTGCCGGCGCTGGCGGC
GGAGACCGTCAGCACTTCCAATCCGTACGGCATCGACGCGCTGTGGTCGCAAGGCGACTTCGTGGCGAAGGGCACGCTGA
TCATTCTGCTGATCATGTCGGCGTCCACCTGGTACGTCGGCATCGTCAAGCTGCTGGAACAACGCCGCCTGATCAAGCAG
GGGCATGAACTGCTGGCCCACCACGGCGTGGACCTGCAAAAGGCCGCCAGCGAGCTGGCGGACGAAGGGATGTACAGCGC
GGTGGCGCAAGCCGGCATTGAAGCCGCCGCCGAGCACAAGGGCGAGCTGGCCAACCGCGTGGACCTGAATACCTGGGTGG
CGATGGCGATTTCGGACGCGGTGGACTCCGCCAGCCATCACATGCAGAACGGTCTGTCGGTGATCGCCACCGTGGGCTCC
ACCGCGCCGTTCGTCGGCCTGTTCGGCACGGTGTGGGGCATCTACCACGCGCTGGTGAAGATCGGCACTTCGGGCCAGGC
TTCCATCGATAAAGTGGCCGGCCCGGTGGGCGAAGCGCTGATCATGACCGCGATCGGCCTGGCGGTGGCGGTGCCGGCGG
TGCTGGGATACAACTGGCTGGTGCGGCGCAACAAGCTGGTGCTGGACAACGTGCGCGTGGTGTCGGGCCGTCTGCACGCC
AGCCTGCTGAACAACCCGAGCCGGTAA

Upstream 100 bases:

>100_bases
CTGCCAGGCCAATTCCCAGCTGAAACAGGAATTCGGCTTCAAACTCGACTCTGGCGCCTAAGTCGCCCAGGGCATCTCAA
GACACAAAGGAGCAAATACC

Downstream 100 bases:

>100_bases
TCGAAGATGGCCCGTTACACGCGATTTGGCCACGGCAAGGGCGACGAGGACCAGGTGCTGTCTGCGATCAACACCACGCC
GCTGGTGGACGTGATGCTGG

Product: biopolymer transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTKITRAFLGKVLGAAGLLTALPALAAETVSTSNPYGIDALWSQGDFVAKGTLIILLIMSASTWYVGIVKLLEQRRLIKQ
GHELLAHHGVDLQKAASELADEGMYSAVAQAGIEAAAEHKGELANRVDLNTWVAMAISDAVDSASHHMQNGLSVIATVGS
TAPFVGLFGTVWGIYHALVKIGTSGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKLVLDNVRVVSGRLHA
SLLNNPSR

Sequences:

>Translated_248_residues
MTKITRAFLGKVLGAAGLLTALPALAAETVSTSNPYGIDALWSQGDFVAKGTLIILLIMSASTWYVGIVKLLEQRRLIKQ
GHELLAHHGVDLQKAASELADEGMYSAVAQAGIEAAAEHKGELANRVDLNTWVAMAISDAVDSASHHMQNGLSVIATVGS
TAPFVGLFGTVWGIYHALVKIGTSGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKLVLDNVRVVSGRLHA
SLLNNPSR
>Mature_247_residues
TKITRAFLGKVLGAAGLLTALPALAAETVSTSNPYGIDALWSQGDFVAKGTLIILLIMSASTWYVGIVKLLEQRRLIKQG
HELLAHHGVDLQKAASELADEGMYSAVAQAGIEAAAEHKGELANRVDLNTWVAMAISDAVDSASHHMQNGLSVIATVGST
APFVGLFGTVWGIYHALVKIGTSGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKLVLDNVRVVSGRLHAS
LLNNPSR

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=190, Percent_Identity=33.1578947368421, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786958, Length=97, Percent_Identity=47.4226804123711, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26037; Mature: 25905

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKITRAFLGKVLGAAGLLTALPALAAETVSTSNPYGIDALWSQGDFVAKGTLIILLIMS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEHHHHHHHHHHH
ASTWYVGIVKLLEQRRLIKQGHELLAHHGVDLQKAASELADEGMYSAVAQAGIEAAAEHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GELANRVDLNTWVAMAISDAVDSASHHMQNGLSVIATVGSTAPFVGLFGTVWGIYHALVK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IGTSGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKLVLDNVRVVSGRLHA
CCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHH
SLLNNPSR
HHHCCCCC
>Mature Secondary Structure 
TKITRAFLGKVLGAAGLLTALPALAAETVSTSNPYGIDALWSQGDFVAKGTLIILLIMS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCEEEHHHHHHHHHHH
ASTWYVGIVKLLEQRRLIKQGHELLAHHGVDLQKAASELADEGMYSAVAQAGIEAAAEHK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GELANRVDLNTWVAMAISDAVDSASHHMQNGLSVIATVGSTAPFVGLFGTVWGIYHALVK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
IGTSGQASIDKVAGPVGEALIMTAIGLAVAVPAVLGYNWLVRRNKLVLDNVRVVSGRLHA
CCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHH
SLLNNPSR
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9140974 [H]