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The map label for this gene is argS

Identifier: 34497417

GI number: 34497417

Start: 2133825

End: 2135543

Strand: Direct

Name: argS

Synonym: CV_1962

Alternate gene names: 34497417

Gene position: 2133825-2135543 (Clockwise)

Preceding gene: 34497415

Following gene: 34497418

Centisome position: 44.91

GC content: 63.87

Gene sequence:

>1719_bases
ATGACGATTCATCAACTGATCAACGAACGGGTACAGGCGGCGCTGGCGGCAGCCGGCGCGCCTGACGCGCCTGCCGTGGT
CCAGCCGGCATCCAAGCCGGAATTCGGCGACTACCAGGCCAACGGCGTGATGGGCGCCGCCAAGGCATTGAAAACCAATC
CGCGCGCGCTGGCCGAAAAGGTCGTCGCCGCGCTGGATCTTGCCGGCATCGCCGACAAGGTGGAAATCGCCGGCCCGGGT
TTCATCAATATTCATCTAGCCCCTGAATATCTGGCCCGACGAAGCGAAGCCGCCCTGAAAGACGACAAGCTGGGCATCGC
GCCGGTGAAGCCGCTGCGCGTGATGGTGGAGTACTCGTCGCCCAACCTGGCCAAGGAGATGCACGTCGGCCACCTGCGCT
CGTCCATCATCGGCGACGCGCTGGCGCGGGTGATGGAATACGTCGGCCACGACGTGGTCCGCGCCAACCACGTCGGCGAC
TGGGGCACCCAGTTCGGCATGCTGGTGGCCTACCTGGTGGAAACCCGCCACGCCGGCGACGCCGACCTGCAGCTGTCCGA
CCTGGAAACTTTCTACCGCAACGCCAAGATCCGCTTCGACGAGAGCGAGGACTTCGCCAACACCGCGCGCGACTATGTGG
TGAAGCTGCAGGGCGGCGACGAGGAGGTGCTGAAGCTGTGGCGCCAGTTCGTCGACGTGTCGCTGAAACACTGCGAGGAC
GTGTACGAAAAGCTGAACGTCGGCCTGAAGCGCGAGCACGTGCGCGGCGAGTCGTCGTATAACGACGACCTGCCGGTGAT
CGTGCAGGAGCTGCGCGAGAAGGGCCTGCTGACCGAGGACGATGGCGCCCAGGTGGTGTTCCTGGATGAATTCCGCACCC
AGGAAGACAAGCCGATGGGCGTGATCGTCCAGAAAAAGGACGGCGGCTTCATCTACACCACCACCGACATCGGCGCGGTG
CGCTACCGCCACCGCGAGTTGAAGCTGGATCGCGTGATCTACGTGGTGGACGCGCGCCAGAGCCAGCACTTCGCCCAGAT
GTTCACCATCTGTCGCAAGGCCGGTTTCGCGCCGGAAGCGATGAAGCTGGAGCATGTCGGCTTCGGCGTGATGATGGGCG
ACGACGGCAAGCCGTTCAAGACCCGTTCCGGCGGCACCGTCAAGCTGATCGAGCTGTTGAACGAGGCCGAGGAGCGCGCC
TACGCGCTGGTGTCCGAGAAAAATCCGGACCTGTCCGACGCGCAGAAGCGCGAGATCGCCAACGCTGTCGGCATCGGTGC
GGTGAAGTATGCCGATCTGTCCAAGAACCGGATGAGCGATTACATCTTCAACTGGGACACCATGCTGGCTTTCGAGGGCA
ACACCGCTCCGTATCTGCAGTACGCCTACACTCGCGTGCAGAGCGTGTTCCGCAAGGCCGAGGACTACGACGCCAACGCC
AGGATCGTCATCACCGAGCCGGCCGAGAAGCAGCTGGCCGCCGCGCTGGCGCAGTTCGAGGACACGCTGAACTCGGTGGT
GGAAGGCTGCTATCCGCACTATCTGTCGCTGTACCTGTACCAGATCGCCACGCTGTTCTCCCGCTTCTACGAAGCCTGCC
CGATCCTGAAGAGCGAGGGCGAGGTGCGCGCCAGCCGCCTGCAACTGGCCGCGCTGACCGCCAAGACGCTGCGCACCGGC
CTGGACCTGCTGGGGATCAAGGTGCTGGAATCGATGTAA

Upstream 100 bases:

>100_bases
CATTGCCCGCTTGGGCTTAGGCGCATACAATCAAATACATATTTTTTTTCAGAAGCGAAGACATAATTTTTCGTTTTCGC
GGCATTTCGTGGGGCTATCA

Downstream 100 bases:

>100_bases
GCGCCGTCCCTGGTTCGATGGAAAGCCCCGCCCGAAACGGCGGGGTTTTTTTATCCGCGGTAGCGGGCGGCTTTGGGCTG
GCGGCCGCCATATATGGAAC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTIHQLINERVQAALAAAGAPDAPAVVQPASKPEFGDYQANGVMGAAKALKTNPRALAEKVVAALDLAGIADKVEIAGPG
FINIHLAPEYLARRSEAALKDDKLGIAPVKPLRVMVEYSSPNLAKEMHVGHLRSSIIGDALARVMEYVGHDVVRANHVGD
WGTQFGMLVAYLVETRHAGDADLQLSDLETFYRNAKIRFDESEDFANTARDYVVKLQGGDEEVLKLWRQFVDVSLKHCED
VYEKLNVGLKREHVRGESSYNDDLPVIVQELREKGLLTEDDGAQVVFLDEFRTQEDKPMGVIVQKKDGGFIYTTTDIGAV
RYRHRELKLDRVIYVVDARQSQHFAQMFTICRKAGFAPEAMKLEHVGFGVMMGDDGKPFKTRSGGTVKLIELLNEAEERA
YALVSEKNPDLSDAQKREIANAVGIGAVKYADLSKNRMSDYIFNWDTMLAFEGNTAPYLQYAYTRVQSVFRKAEDYDANA
RIVITEPAEKQLAAALAQFEDTLNSVVEGCYPHYLSLYLYQIATLFSRFYEACPILKSEGEVRASRLQLAALTAKTLRTG
LDLLGIKVLESM

Sequences:

>Translated_572_residues
MTIHQLINERVQAALAAAGAPDAPAVVQPASKPEFGDYQANGVMGAAKALKTNPRALAEKVVAALDLAGIADKVEIAGPG
FINIHLAPEYLARRSEAALKDDKLGIAPVKPLRVMVEYSSPNLAKEMHVGHLRSSIIGDALARVMEYVGHDVVRANHVGD
WGTQFGMLVAYLVETRHAGDADLQLSDLETFYRNAKIRFDESEDFANTARDYVVKLQGGDEEVLKLWRQFVDVSLKHCED
VYEKLNVGLKREHVRGESSYNDDLPVIVQELREKGLLTEDDGAQVVFLDEFRTQEDKPMGVIVQKKDGGFIYTTTDIGAV
RYRHRELKLDRVIYVVDARQSQHFAQMFTICRKAGFAPEAMKLEHVGFGVMMGDDGKPFKTRSGGTVKLIELLNEAEERA
YALVSEKNPDLSDAQKREIANAVGIGAVKYADLSKNRMSDYIFNWDTMLAFEGNTAPYLQYAYTRVQSVFRKAEDYDANA
RIVITEPAEKQLAAALAQFEDTLNSVVEGCYPHYLSLYLYQIATLFSRFYEACPILKSEGEVRASRLQLAALTAKTLRTG
LDLLGIKVLESM
>Mature_571_residues
TIHQLINERVQAALAAAGAPDAPAVVQPASKPEFGDYQANGVMGAAKALKTNPRALAEKVVAALDLAGIADKVEIAGPGF
INIHLAPEYLARRSEAALKDDKLGIAPVKPLRVMVEYSSPNLAKEMHVGHLRSSIIGDALARVMEYVGHDVVRANHVGDW
GTQFGMLVAYLVETRHAGDADLQLSDLETFYRNAKIRFDESEDFANTARDYVVKLQGGDEEVLKLWRQFVDVSLKHCEDV
YEKLNVGLKREHVRGESSYNDDLPVIVQELREKGLLTEDDGAQVVFLDEFRTQEDKPMGVIVQKKDGGFIYTTTDIGAVR
YRHRELKLDRVIYVVDARQSQHFAQMFTICRKAGFAPEAMKLEHVGFGVMMGDDGKPFKTRSGGTVKLIELLNEAEERAY
ALVSEKNPDLSDAQKREIANAVGIGAVKYADLSKNRMSDYIFNWDTMLAFEGNTAPYLQYAYTRVQSVFRKAEDYDANAR
IVITEPAEKQLAAALAQFEDTLNSVVEGCYPHYLSLYLYQIATLFSRFYEACPILKSEGEVRASRLQLAALTAKTLRTGL
DLLGIKVLESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=580, Percent_Identity=38.7931034482759, Blast_Score=408, Evalue=1e-114,
Organism=Homo sapiens, GI197100773, Length=477, Percent_Identity=31.0272536687631, Blast_Score=208, Evalue=1e-53,
Organism=Escherichia coli, GI1788184, Length=577, Percent_Identity=58.7521663778163, Blast_Score=687, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71985061, Length=575, Percent_Identity=41.2173913043478, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71985068, Length=544, Percent_Identity=41.1764705882353, Blast_Score=389, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17532153, Length=497, Percent_Identity=28.3702213279678, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6320548, Length=544, Percent_Identity=33.4558823529412, Blast_Score=279, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6321883, Length=545, Percent_Identity=31.3761467889908, Blast_Score=262, Evalue=1e-70,
Organism=Drosophila melanogaster, GI18859963, Length=577, Percent_Identity=39.1681109185442, Blast_Score=408, Evalue=1e-114,
Organism=Drosophila melanogaster, GI28571570, Length=491, Percent_Identity=31.9755600814664, Blast_Score=214, Evalue=2e-55,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_CHRVO (Q7NWM1)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_901632.1
- ProteinModelPortal:   Q7NWM1
- SMR:   Q7NWM1
- GeneID:   2549042
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_1962
- NMPDR:   fig|243365.1.peg.1962
- HOGENOM:   HBG695395
- OMA:   HMGFGTM
- PhylomeDB:   Q7NWM1
- ProtClustDB:   PRK01611
- BioCyc:   CVIO243365:CV_1962-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 63582; Mature: 63451

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIHQLINERVQAALAAAGAPDAPAVVQPASKPEFGDYQANGVMGAAKALKTNPRALAEK
CCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
VVAALDLAGIADKVEIAGPGFINIHLAPEYLARRSEAALKDDKLGIAPVKPLRVMVEYSS
HHHHHHHHCCCCCEEECCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
PNLAKEMHVGHLRSSIIGDALARVMEYVGHDVVRANHVGDWGTQFGMLVAYLVETRHAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCCCC
ADLQLSDLETFYRNAKIRFDESEDFANTARDYVVKLQGGDEEVLKLWRQFVDVSLKHCED
CCCCHHHHHHHHHCCEEEECCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VYEKLNVGLKREHVRGESSYNDDLPVIVQELREKGLLTEDDGAQVVFLDEFRTQEDKPMG
HHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCE
VIVQKKDGGFIYTTTDIGAVRYRHRELKLDRVIYVVDARQSQHFAQMFTICRKAGFAPEA
EEEEECCCCEEEEECCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCH
MKLEHVGFGVMMGDDGKPFKTRSGGTVKLIELLNEAEERAYALVSEKNPDLSDAQKREIA
HEEEECCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHCCCCCCCCHHHHHHHH
NAVGIGAVKYADLSKNRMSDYIFNWDTMLAFEGNTAPYLQYAYTRVQSVFRKAEDYDANA
HHHCCCCEEECCCCHHHHHHHEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
RIVITEPAEKQLAAALAQFEDTLNSVVEGCYPHYLSLYLYQIATLFSRFYEACPILKSEG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EVRASRLQLAALTAKTLRTGLDLLGIKVLESM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIHQLINERVQAALAAAGAPDAPAVVQPASKPEFGDYQANGVMGAAKALKTNPRALAEK
CHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
VVAALDLAGIADKVEIAGPGFINIHLAPEYLARRSEAALKDDKLGIAPVKPLRVMVEYSS
HHHHHHHHCCCCCEEECCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
PNLAKEMHVGHLRSSIIGDALARVMEYVGHDVVRANHVGDWGTQFGMLVAYLVETRHAGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHCCCCC
ADLQLSDLETFYRNAKIRFDESEDFANTARDYVVKLQGGDEEVLKLWRQFVDVSLKHCED
CCCCHHHHHHHHHCCEEEECCCHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VYEKLNVGLKREHVRGESSYNDDLPVIVQELREKGLLTEDDGAQVVFLDEFRTQEDKPMG
HHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCE
VIVQKKDGGFIYTTTDIGAVRYRHRELKLDRVIYVVDARQSQHFAQMFTICRKAGFAPEA
EEEEECCCCEEEEECCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCH
MKLEHVGFGVMMGDDGKPFKTRSGGTVKLIELLNEAEERAYALVSEKNPDLSDAQKREIA
HEEEECCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHCCCCCCCCHHHHHHHH
NAVGIGAVKYADLSKNRMSDYIFNWDTMLAFEGNTAPYLQYAYTRVQSVFRKAEDYDANA
HHHCCCCEEECCCCHHHHHHHEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCC
RIVITEPAEKQLAAALAQFEDTLNSVVEGCYPHYLSLYLYQIATLFSRFYEACPILKSEG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EVRASRLQLAALTAKTLRTGLDLLGIKVLESM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782