Click here to switch to the map view.

The map label for this gene is bvgS [H]

Identifier: 34497406

GI number: 34497406

Start: 2123468

End: 2125156

Strand: Direct

Name: bvgS [H]

Synonym: CV_1951

Alternate gene names: 34497406

Gene position: 2123468-2125156 (Clockwise)

Preceding gene: 34497403

Following gene: 34497407

Centisome position: 44.69

GC content: 65.6

Gene sequence:

>1689_bases
CTGGCCTGTCTCGACATCACCGAGCGCAAGATGGCCGAATTCGAGCTGAGGATGGCGCGCGACCAGGCCAACGCCGCCAA
CCGCGCCAAGAGCGCCTTCCTGGCGACGATGAGCCATGAAATCCGCACGCCGATGAACGGCGTGCTGGGGATGCTGGAAC
TGCTGGCGATGACCCGGCTGGACGCTGAGCAGAGCGACACCGTCGCCACCATCCAGGATTCGGCCAACACGCTGCTGCGA
TTGATAGACGACATCCTGGATTTCTCCAAGATCGAGGCGGACCGGCTGGAGATCGTGCCCACCCGCACCGCGATACGGCC
TTTCATGGACAGCGTGCGCAGCCTCTACCACGAGAACGCCAGCAAGAAGGGCCTGGAGCTGACGCTGACGCTGGACGACA
AGCTGGCACCGACGCTGGTCATCGACCCGCTGCGGGTGAGGCAGATCCTGCAGAACTTCATCAGCAACGCCATCAAGTTC
ACTGCCAGCGGCAAGGTGGACATCCGGGTCAAGGTGATGGATACCGTGGCCAATTACCAGGTGCTGAGCTTCGAGGTCGA
GGACACCGGCATCGGCATGTCCCAGGAGCAACTGAGCAAGCTGTTCCAGCCGTTCACCCAGGCGGATTCCGAAACCACCC
GCCGTTTCGGCGGAACGGGGCTGGGGCTGGCGATCTGCCGGCGGCTGGCCGGCCTGATGGGCGGCCACGTGGAGATGGAG
AGCGAGCAGGGCAAGGGCAGCTGCGCCAGGCTGTTGCTGGAGGTGGAGTGGCTGGCCGAACAGGTGGAGCCGGTCATGCT
GCCGGAGCAGCGCGTGCCGCTGGAGACCGTGATCGCCGCCGCTCAGGCCGACAAGGAGATCAGCCTGGGCAGCGGACTGT
TTCCCATTCTGTTCGCCGAGGACAACCCCACCAATCGCAAGCTGACGCTCAAGCAGCTGGAAAAGCTCGGCTACCCGGCG
GACTGGGCCGAGGACGGCGACCGGGCCTTCAGCAAATGGCTGTCCGGACGTTACTCGCTGATTCTGACCGACTGCCACAT
GCCCGGAATCGACGGCTACCAACTGGCGCGGCTGGTGCGCGCCCATGAGGAGTCGCATCCCGAGCGCGGCCGCATTCCCA
TCGTCGCCTGCACCGCCAACGCGGCCAAGGAGGAGGTGGACAAGACGCGCGAAGCCGGCATGGACGATTTCCTGACCAAG
CCGCTGTCCATCCTGGCGCTTGAAGCGACATTGCGAAAATGGATGGGCTCCATGTCCGGGTCTCCGCCGGACGGCGCCGC
CGCGTCGTCCGACGTCCCTGGCAAGGCCGAGGTCGCGGAGCCGCCGCCTCTGGATGCGCCGCGGATCCCGGTGGACCGAA
GCGTGCTCGAGGTGTACAGCAATGGCGAGTTGAGCGTGGAGCTGGAGATCCTGCGCGAATTCCAGACCGGCAACAGCGAG
GACGTGGCCGAACTGCGCGCGGCGATGGCCGCGGAGGATGCGGAGCGCATCGGCTTTTCCGCGCACCGCATCAAGGGCGC
CAGCCGCATGGTGGGAGCCAACGGCATGGGCGACGCCGCCGAGGCGGTGGAGAAGGCGGGCAAGGCGCGCGACCTGGAGC
TGGCCAGGAAAAAGATGGTTTTCTTCGAAGACCAGCTGGCCGTCTTCGAAAACTGGCTGGCCAGCCAGGGCGAAACGGTC
GCCGAATAG

Upstream 100 bases:

>100_bases
CCATTGCGAGCTGGAGTGCCTGACCGGCACCGGCCGGCCGATCTGGGTGCTGTTCGAGGGGCAGCTGCTGTTCCCCGACG
CCAGCGAGTCGGTGATCATC

Downstream 100 bases:

>100_bases
CGCCGCCCGCCATTCGGGCCAGTCCATTCCGCCCAGGCTTGGCCTGGATGCGGGCCGGGCTTAGAATCCGCTCTCATGAA
CCACGCACAATCGCTTTATC

Product: two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MACLDITERKMAEFELRMARDQANAANRAKSAFLATMSHEIRTPMNGVLGMLELLAMTRLDAEQSDTVATIQDSANTLLR
LIDDILDFSKIEADRLEIVPTRTAIRPFMDSVRSLYHENASKKGLELTLTLDDKLAPTLVIDPLRVRQILQNFISNAIKF
TASGKVDIRVKVMDTVANYQVLSFEVEDTGIGMSQEQLSKLFQPFTQADSETTRRFGGTGLGLAICRRLAGLMGGHVEME
SEQGKGSCARLLLEVEWLAEQVEPVMLPEQRVPLETVIAAAQADKEISLGSGLFPILFAEDNPTNRKLTLKQLEKLGYPA
DWAEDGDRAFSKWLSGRYSLILTDCHMPGIDGYQLARLVRAHEESHPERGRIPIVACTANAAKEEVDKTREAGMDDFLTK
PLSILALEATLRKWMGSMSGSPPDGAAASSDVPGKAEVAEPPPLDAPRIPVDRSVLEVYSNGELSVELEILREFQTGNSE
DVAELRAAMAAEDAERIGFSAHRIKGASRMVGANGMGDAAEAVEKAGKARDLELARKKMVFFEDQLAVFENWLASQGETV
AE

Sequences:

>Translated_562_residues
MACLDITERKMAEFELRMARDQANAANRAKSAFLATMSHEIRTPMNGVLGMLELLAMTRLDAEQSDTVATIQDSANTLLR
LIDDILDFSKIEADRLEIVPTRTAIRPFMDSVRSLYHENASKKGLELTLTLDDKLAPTLVIDPLRVRQILQNFISNAIKF
TASGKVDIRVKVMDTVANYQVLSFEVEDTGIGMSQEQLSKLFQPFTQADSETTRRFGGTGLGLAICRRLAGLMGGHVEME
SEQGKGSCARLLLEVEWLAEQVEPVMLPEQRVPLETVIAAAQADKEISLGSGLFPILFAEDNPTNRKLTLKQLEKLGYPA
DWAEDGDRAFSKWLSGRYSLILTDCHMPGIDGYQLARLVRAHEESHPERGRIPIVACTANAAKEEVDKTREAGMDDFLTK
PLSILALEATLRKWMGSMSGSPPDGAAASSDVPGKAEVAEPPPLDAPRIPVDRSVLEVYSNGELSVELEILREFQTGNSE
DVAELRAAMAAEDAERIGFSAHRIKGASRMVGANGMGDAAEAVEKAGKARDLELARKKMVFFEDQLAVFENWLASQGETV
AE
>Mature_561_residues
ACLDITERKMAEFELRMARDQANAANRAKSAFLATMSHEIRTPMNGVLGMLELLAMTRLDAEQSDTVATIQDSANTLLRL
IDDILDFSKIEADRLEIVPTRTAIRPFMDSVRSLYHENASKKGLELTLTLDDKLAPTLVIDPLRVRQILQNFISNAIKFT
ASGKVDIRVKVMDTVANYQVLSFEVEDTGIGMSQEQLSKLFQPFTQADSETTRRFGGTGLGLAICRRLAGLMGGHVEMES
EQGKGSCARLLLEVEWLAEQVEPVMLPEQRVPLETVIAAAQADKEISLGSGLFPILFAEDNPTNRKLTLKQLEKLGYPAD
WAEDGDRAFSKWLSGRYSLILTDCHMPGIDGYQLARLVRAHEESHPERGRIPIVACTANAAKEEVDKTREAGMDDFLTKP
LSILALEATLRKWMGSMSGSPPDGAAASSDVPGKAEVAEPPPLDAPRIPVDRSVLEVYSNGELSVELEILREFQTGNSED
VAELRAAMAAEDAERIGFSAHRIKGASRMVGANGMGDAAEAVEKAGKARDLELARKKMVFFEDQLAVFENWLASQGETVA
E

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=521, Percent_Identity=33.0134357005758, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1788713, Length=555, Percent_Identity=30.8108108108108, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=43.1535269709544, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=38.5245901639344, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081816, Length=347, Percent_Identity=34.2939481268012, Blast_Score=169, Evalue=6e-43,
Organism=Escherichia coli, GI1788393, Length=208, Percent_Identity=30.2884615384615, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=29.2372881355932, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=27.6315789473684, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=28.6995515695067, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=27.6497695852535, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=26.530612244898, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=253, Percent_Identity=24.5059288537549, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788191, Length=132, Percent_Identity=31.0606060606061, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=229, Percent_Identity=25.764192139738, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=95, Percent_Identity=40, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61682; Mature: 61551

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACLDITERKMAEFELRMARDQANAANRAKSAFLATMSHEIRTPMNGVLGMLELLAMTRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
DAEQSDTVATIQDSANTLLRLIDDILDFSKIEADRLEIVPTRTAIRPFMDSVRSLYHENA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
SKKGLELTLTLDDKLAPTLVIDPLRVRQILQNFISNAIKFTASGKVDIRVKVMDTVANYQ
CCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEHHCCEE
VLSFEVEDTGIGMSQEQLSKLFQPFTQADSETTRRFGGTGLGLAICRRLAGLMGGHVEME
EEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEC
SEQGKGSCARLLLEVEWLAEQVEPVMLPEQRVPLETVIAAAQADKEISLGSGLFPILFAE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEC
DNPTNRKLTLKQLEKLGYPADWAEDGDRAFSKWLSGRYSLILTDCHMPGIDGYQLARLVR
CCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
AHEESHPERGRIPIVACTANAAKEEVDKTREAGMDDFLTKPLSILALEATLRKWMGSMSG
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCC
SPPDGAAASSDVPGKAEVAEPPPLDAPRIPVDRSVLEVYSNGELSVELEILREFQTGNSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHCCCCH
DVAELRAAMAAEDAERIGFSAHRIKGASRMVGANGMGDAAEAVEKAGKARDLELARKKMV
HHHHHHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
FFEDQLAVFENWLASQGETVAE
HHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ACLDITERKMAEFELRMARDQANAANRAKSAFLATMSHEIRTPMNGVLGMLELLAMTRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
DAEQSDTVATIQDSANTLLRLIDDILDFSKIEADRLEIVPTRTAIRPFMDSVRSLYHENA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCC
SKKGLELTLTLDDKLAPTLVIDPLRVRQILQNFISNAIKFTASGKVDIRVKVMDTVANYQ
CCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEHHCCEE
VLSFEVEDTGIGMSQEQLSKLFQPFTQADSETTRRFGGTGLGLAICRRLAGLMGGHVEME
EEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEC
SEQGKGSCARLLLEVEWLAEQVEPVMLPEQRVPLETVIAAAQADKEISLGSGLFPILFAE
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEC
DNPTNRKLTLKQLEKLGYPADWAEDGDRAFSKWLSGRYSLILTDCHMPGIDGYQLARLVR
CCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
AHEESHPERGRIPIVACTANAAKEEVDKTREAGMDDFLTKPLSILALEATLRKWMGSMSG
HHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCC
SPPDGAAASSDVPGKAEVAEPPPLDAPRIPVDRSVLEVYSNGELSVELEILREFQTGNSE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHCCCCH
DVAELRAAMAAEDAERIGFSAHRIKGASRMVGANGMGDAAEAVEKAGKARDLELARKKMV
HHHHHHHHHHHHHHHHHCCHHHHHCCHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHH
FFEDQLAVFENWLASQGETVAE
HHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]