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The map label for this gene is rcsC [H]

Identifier: 34497374

GI number: 34497374

Start: 2090079

End: 2090459

Strand: Direct

Name: rcsC [H]

Synonym: CV_1919

Alternate gene names: 34497374

Gene position: 2090079-2090459 (Clockwise)

Preceding gene: 34497373

Following gene: 34497376

Centisome position: 43.99

GC content: 62.47

Gene sequence:

>381_bases
TTGAATCGGGTTGTCAGAAAAATACTGCTGGTGGAAGATCAGCCGCTCAATCTGTCGTTGCTGGAGCACATGCTGGACTG
GTTCGACTTGCGGGCGGATGTGGCGATAGACGGCCTGCAAGCGGTGGAAATGGCCTGCACCGGCGCCTACGCGCTGGTGC
TGATGGATATCCAGCTGCCGGGCATAGATGGCGTGGAGGCCACGCGCCGGATTCGAAGCTGCGGGCTGCCGTGTCAGCCC
GCCATCATCGCGATGACCGCCAACGCCTACCAGGGAGAGCGCCGCCGCTGCCTGGAGGCGGGCATGGATGACATGCTGGT
CAAGCCGTTCAAGCTCGACGACTTGCGCCGCGTGATCGATGCCTACCTGCCTTCGGCTTGA

Upstream 100 bases:

>100_bases
GCGCGGGGCCTTGGCTCTGTGCTGATATAGACTATCCTGAAAGAGACAACGGCGGCGCCGCCAGGCGCCGCCGTTGTCTT
GCCGTTTTCAGGGGAAGAAA

Downstream 100 bases:

>100_bases
TGAGGCGCAGGCATCGCGCCCGTCTTAGAAACGCCCCTCGCTGTAGTCCGCTATCGCTGTTTCGATTTCCTCCCGGCTGT
TCATCACGAACGGTCCCCAT

Product: hypothetical protein

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MNRVVRKILLVEDQPLNLSLLEHMLDWFDLRADVAIDGLQAVEMACTGAYALVLMDIQLPGIDGVEATRRIRSCGLPCQP
AIIAMTANAYQGERRRCLEAGMDDMLVKPFKLDDLRRVIDAYLPSA

Sequences:

>Translated_126_residues
MNRVVRKILLVEDQPLNLSLLEHMLDWFDLRADVAIDGLQAVEMACTGAYALVLMDIQLPGIDGVEATRRIRSCGLPCQP
AIIAMTANAYQGERRRCLEAGMDDMLVKPFKLDDLRRVIDAYLPSA
>Mature_126_residues
MNRVVRKILLVEDQPLNLSLLEHMLDWFDLRADVAIDGLQAVEMACTGAYALVLMDIQLPGIDGVEATRRIRSCGLPCQP
AIIAMTANAYQGERRRCLEAGMDDMLVKPFKLDDLRRVIDAYLPSA

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=115, Percent_Identity=38.2608695652174, Blast_Score=81, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=125, Percent_Identity=33.6, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=117, Percent_Identity=37.6068376068376, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1788713, Length=111, Percent_Identity=37.8378378378378, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1786784, Length=111, Percent_Identity=36.9369369369369, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=109, Percent_Identity=33.9449541284404, Blast_Score=61, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=38.7931034482759, Blast_Score=77, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322044, Length=136, Percent_Identity=30.1470588235294, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 14074; Mature: 14074

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
8.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVVRKILLVEDQPLNLSLLEHMLDWFDLRADVAIDGLQAVEMACTGAYALVLMDIQLP
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
GIDGVEATRRIRSCGLPCQPAIIAMTANAYQGERRRCLEAGMDDMLVKPFKLDDLRRVID
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHCCCCCHHHHHHHHH
AYLPSA
HHCCCC
>Mature Secondary Structure
MNRVVRKILLVEDQPLNLSLLEHMLDWFDLRADVAIDGLQAVEMACTGAYALVLMDIQLP
CHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECC
GIDGVEATRRIRSCGLPCQPAIIAMTANAYQGERRRCLEAGMDDMLVKPFKLDDLRRVID
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHCCCHHHHCCCCCHHHHHHHHH
AYLPSA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]