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The map label for this gene is phnL [H]

Identifier: 34497296

GI number: 34497296

Start: 1996548

End: 1997255

Strand: Reverse

Name: phnL [H]

Synonym: CV_1841

Alternate gene names: 34497296

Gene position: 1997255-1996548 (Counterclockwise)

Preceding gene: 34497297

Following gene: 34497295

Centisome position: 42.04

GC content: 69.63

Gene sequence:

>708_bases
ATGAATCTATTGATAGACGCGCAAAATCTGAGCAAGACCTTCACCCTGCATCAACAGGGCGGGCTGCGGCTGCCGGTGCT
GACCGAGGTCTCGCTGCAGGCGGCCGCCGGCGAATGCGTGGCGCTGGCCGGCCCGTCCGGCGCCGGCAAGAGCACCTTGC
TGAAAGCGCTGTACGCCAATTATCTAGTCGAAAACGGCCGCGTCGGCGTGCTTCACCAGGGCGCATGGGTGGACATGGCG
CGCGCGCTGCCGCATGAAATCGCCGCCGTACGCCGCCATACCTTGGGCTACGTCAGCCAGTTCCTGCGCGTGATCCCGCG
CGTGTCGGCGCTGGACATCGTCACGGAGCCGCTGCGCGAATGGGGGGCCGCCGACGCCGAAGCCAGGCTGGCCGCCGGCG
AATGGCTGGCGCGGCTGAACATCGCCGAGCGGCTGTGGAGCCTGCCGCCGGCCACCTTCTCCGGCGGAGAGCAGCAGCGC
GTCAACATCGCGCGCGGCATGATCGCGCCGCGGCCCATCCTGCTGCTGGACGAGCCGACCGCCTCGCTGGACGCCGCCAA
CCGCGAGGTGGTGGTCCAGCTGATGCGCGAGGCGCTGGCCCGCCGCGCGGCGCTGATCGGCATCTTCCACGACGCGCCCA
CCCGCGACGCCATCGCCACCCGCGTGTTCCAGGTTCCCCTGGCGCGACAAACGGAAACCGCAGCATGA

Upstream 100 bases:

>100_bases
GGGCGCGTGGTGGAGGCCGGCCTCACCGACCAGATCCTCGACGACCCGCAGCACCCGTACAGCCAGTTGCTGGTGTCTTC
CATCCTGCAGGCCTGAAATC

Downstream 100 bases:

>100_bases
AACAGATTTTGAACCACGCCCGCATCGTGCTGGCCGACCGCGTCATCGACAACGGCGCGCTGGAAATCAACGACGGCCGG
ATCGCCGCGATACACGAACA

Product: phosphonates transport ATP-binding protein phnL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MNLLIDAQNLSKTFTLHQQGGLRLPVLTEVSLQAAAGECVALAGPSGAGKSTLLKALYANYLVENGRVGVLHQGAWVDMA
RALPHEIAAVRRHTLGYVSQFLRVIPRVSALDIVTEPLREWGAADAEARLAAGEWLARLNIAERLWSLPPATFSGGEQQR
VNIARGMIAPRPILLLDEPTASLDAANREVVVQLMREALARRAALIGIFHDAPTRDAIATRVFQVPLARQTETAA

Sequences:

>Translated_235_residues
MNLLIDAQNLSKTFTLHQQGGLRLPVLTEVSLQAAAGECVALAGPSGAGKSTLLKALYANYLVENGRVGVLHQGAWVDMA
RALPHEIAAVRRHTLGYVSQFLRVIPRVSALDIVTEPLREWGAADAEARLAAGEWLARLNIAERLWSLPPATFSGGEQQR
VNIARGMIAPRPILLLDEPTASLDAANREVVVQLMREALARRAALIGIFHDAPTRDAIATRVFQVPLARQTETAA
>Mature_235_residues
MNLLIDAQNLSKTFTLHQQGGLRLPVLTEVSLQAAAGECVALAGPSGAGKSTLLKALYANYLVENGRVGVLHQGAWVDMA
RALPHEIAAVRRHTLGYVSQFLRVIPRVSALDIVTEPLREWGAADAEARLAAGEWLARLNIAERLWSLPPATFSGGEQQR
VNIARGMIAPRPILLLDEPTASLDAANREVVVQLMREALARRAALIGIFHDAPTRDAIATRVFQVPLARQTETAA

Specific function: Part of the binding-protein-dependent transport system for alkylphosphonates. Probably responsible for energy coupling to the transport system [H]

COG id: COG4778

COG function: function code P; ABC-type phosphonate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI9955963, Length=183, Percent_Identity=30.6010928961749, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1790534, Length=219, Percent_Identity=57.0776255707763, Blast_Score=256, Evalue=1e-69,
Organism=Escherichia coli, GI1787029, Length=230, Percent_Identity=33.0434782608696, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788225, Length=236, Percent_Identity=33.0508474576271, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI87081834, Length=198, Percent_Identity=35.3535353535354, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787105, Length=225, Percent_Identity=32, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786703, Length=212, Percent_Identity=35.377358490566, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790544, Length=209, Percent_Identity=33.4928229665072, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787089, Length=201, Percent_Identity=31.8407960199005, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789672, Length=237, Percent_Identity=29.535864978903, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788644, Length=224, Percent_Identity=29.4642857142857, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994997, Length=215, Percent_Identity=29.7674418604651, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI48995001, Length=187, Percent_Identity=33.1550802139037, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786398, Length=202, Percent_Identity=29.7029702970297, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787500, Length=210, Percent_Identity=29.5238095238095, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788450, Length=194, Percent_Identity=32.9896907216495, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789873, Length=174, Percent_Identity=32.7586206896552, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1789032, Length=216, Percent_Identity=32.4074074074074, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786872, Length=223, Percent_Identity=29.5964125560538, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788761, Length=227, Percent_Identity=29.9559471365639, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789962, Length=214, Percent_Identity=29.4392523364486, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693107, Length=209, Percent_Identity=32.0574162679426, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786319, Length=187, Percent_Identity=30.4812834224599, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=213, Percent_Identity=29.1079812206573, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786975, Length=219, Percent_Identity=28.7671232876712, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790739, Length=193, Percent_Identity=30.0518134715026, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787143, Length=205, Percent_Identity=28.2926829268293, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788506, Length=218, Percent_Identity=30.7339449541284, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789593, Length=184, Percent_Identity=34.2391304347826, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081709, Length=221, Percent_Identity=26.2443438914027, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790467, Length=189, Percent_Identity=29.1005291005291, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787712, Length=195, Percent_Identity=29.2307692307692, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786563, Length=176, Percent_Identity=29.5454545454545, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787164, Length=211, Percent_Identity=32.2274881516588, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787112, Length=190, Percent_Identity=28.9473684210526, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082267, Length=200, Percent_Identity=28, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787758, Length=167, Percent_Identity=28.1437125748503, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=194, Percent_Identity=30.4123711340206, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71996550, Length=211, Percent_Identity=30.3317535545024, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=224, Percent_Identity=26.7857142857143, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=195, Percent_Identity=32.3076923076923, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=184, Percent_Identity=32.0652173913043, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=180, Percent_Identity=31.1111111111111, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=184, Percent_Identity=27.7173913043478, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357907, Length=184, Percent_Identity=32.6086956521739, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24659289, Length=196, Percent_Identity=30.1020408163265, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR012701 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 25401; Mature: 25401

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLIDAQNLSKTFTLHQQGGLRLPVLTEVSLQAAAGECVALAGPSGAGKSTLLKALYAN
CCEEEECCCCCCEEEEECCCCCCCCEEHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
YLVENGRVGVLHQGAWVDMARALPHEIAAVRRHTLGYVSQFLRVIPRVSALDIVTEPLRE
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WGAADAEARLAAGEWLARLNIAERLWSLPPATFSGGEQQRVNIARGMIAPRPILLLDEPT
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCC
ASLDAANREVVVQLMREALARRAALIGIFHDAPTRDAIATRVFQVPLARQTETAA
CCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNLLIDAQNLSKTFTLHQQGGLRLPVLTEVSLQAAAGECVALAGPSGAGKSTLLKALYAN
CCEEEECCCCCCEEEEECCCCCCCCEEHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHH
YLVENGRVGVLHQGAWVDMARALPHEIAAVRRHTLGYVSQFLRVIPRVSALDIVTEPLRE
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WGAADAEARLAAGEWLARLNIAERLWSLPPATFSGGEQQRVNIARGMIAPRPILLLDEPT
HCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCC
ASLDAANREVVVQLMREALARRAALIGIFHDAPTRDAIATRVFQVPLARQTETAA
CCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]