Click here to switch to the map view.

The map label for this gene is accA1 [H]

Identifier: 34497217

GI number: 34497217

Start: 1916498

End: 1918453

Strand: Reverse

Name: accA1 [H]

Synonym: CV_1762

Alternate gene names: 34497217

Gene position: 1918453-1916498 (Counterclockwise)

Preceding gene: 34497218

Following gene: 34497216

Centisome position: 40.38

GC content: 68.61

Gene sequence:

>1956_bases
ATGTTCAACAAGATCCTGATCGCCAACAGGGGTGAGATAGCCTGCCGCGTCATCAAGACCGCCAAGGCCCTGGGCATCGC
CACCGTCGCGGTTTATTCGGACGCCGACGCGAACGCCCGCTTCGTCAAGCTGGCCGACGAGGCCTACCGCCTCGGCCCGG
CGCCGGCCGCCGAATCCTATCTGCGCGCCGACCTGATCCTGGCCATCGCCAGACAAAGCGGCGCCCAGGCGGTGCATCCC
GGCTACGGCTTCCTGTCGGAGAACGAAGATTTCGCCGCCGCATGCGAAGCCGCCGGCATCGCCTTCATCGGCCCGCCGGC
CTCGGCCATCGCGGCGATGGGCAGCAAATCCGCCGCCAAGGCGCTGATGGAGAAGGCCGGCGTGCCGCTGGTGCCCGGCT
ACCATGGCGACGAACAGGATCCGGCGCTGCTGCAACAGCAGGCCGACGCCATCGGCTACCCGGTGCTGATCAAGGCCAGC
GCCGGCGGCGGCGGCAAGGGCATGCGCATCGTCGAGCAGGCCGGCGACTTTTCCGCCGCCCTCGCCTCCTGCCAGCGCGA
AGCGCGCGCCAGCTTCGGCGACGACAAGGTGCTGGTCGAGAAATACCTGACCCGCCCGCGCCACGTGGAGATCCAGGTCT
TCGCCGACAAGCTGGGCGGCTGCGTCTACCTGTTCGAACGCGACTGTTCGGTACAGCGTCGCCACCAGAAAGTGCTGGAA
GAAGCCCCAGCCCCCCACCTGCCGCAGGCCACCCGCGAGGCGATGGGCCAGGCGGCGGTGGCCGCCGCGCGCGCGGTGGG
CTATGTCGGCGCCGGCACCGTCGAGTTCATCATGGACGTGGACACCGGCAAGTTCTACTTCATGGAAATGAACACCCGGC
TGCAGGTGGAACACCCGGTGACCGAGATGATCACCGGCCAGGACCTGGTGGCTTGGCAGTTGGCCGTCGCCGCCGGCGGC
GCGCTGCCGCTGGCTCAGGAACAGTTGGCGATGCGCGGCCACGCGATAGAGGCCCGCATCTACGCCGAAGACCCCGACAA
GGGCTTTCTGCCGTCCACCGGCACGCTGGCCCACCTGGCGACGCCGGCCGAATCCGCCCACGTGCGCATCGATACCGGCG
TCGAGCAGGGCGACGCCATCTCGCCGTTCTACGATCCGATGATCGCCAAGCTGATCGTCTGGGGCGAGACCCGCGAGGCC
GCGCTCAGGCAGATGGATGCCGCGCTGGCGCAGTACCGGATCGTGGGCCTGTCCAGCAATGTGTCCTTCCTGCGCCGCAT
CGTGAACCATCCCAGCTTCGCCAGCGGCCAGGTCGACACCGGCCTGATCGCCCGCCACCACGACGCGCTGCTGCCGCCGC
CCGCCGCGCCGACCGCCAGGCAGCTGGCCTTGCTGGCGCTGGCCGAAGCCCTGGCGCATCCAGCCGCCTACCCCGCGCCC
GCCGGCTGGCGGCTGAACGGGCGGCTGACGCGCCGCTTCGCCTTCCAGCGCGACGATGAAGACTACGGCGTGGAACTCCA
ATACCAGGACGACGGCTGCGTCGTCCGCGTCGGTACGGAAAGCTTCCACGCTCGCGCCAGCCTTGCCGGCAACCAGCTGG
AAGCGGTGCTCAATGGCCTTCGCGTCAAGGCCGTCATCGTCCGCCACGGCGCGCGGCGCGCGCTGTTCGAAGGCGGAGAG
CGGCTGAGCGTCGACTTCGTCGATCCCTACGCCTACACCGAGCTGGGCGTGCACGGCGAAACCCACCTCAAGGCGCCGAT
GCCGGGCCGGGTGGTGGCGCTGCTGGCGGAAATCGGCAAAAAGGTGGCCAAAGGCTCGCCGCTGCTGATCCTGGAGGCGA
TGAAAATGGAGCACACCATCACCGCGCCGGGCGACGGCGTGGTGCAGGACTTTTACTTCGCGGCAGGCGAACAGGTTAAC
GATGGTGACGAGCTGGTCGATTTTGCCGCAGAATGA

Upstream 100 bases:

>100_bases
CGCATCGCCTCCATCCGCGCCGGCGACGAGGCCCGCGAGGGGCTGGCTTCGTTCTTCGACAAACGCGCGCCGAAATGGCA
GGAATAACAAGGATAACGCC

Downstream 100 bases:

>100_bases
CGAAGTCATTACCATAGCAACCAAAGGCAAGGATATGCATATCGCCCTGGAAAACATCCAGCAACTGCGCCGGCGCGGGG
AGCACGAGGCCGCGCGCCGC

Product: acyl-CoA carboxylase subunit

Products: NA

Alternate protein names: Biotin carboxylase; Biotin carboxyl carrier protein; BCCP [H]

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MFNKILIANRGEIACRVIKTAKALGIATVAVYSDADANARFVKLADEAYRLGPAPAAESYLRADLILAIARQSGAQAVHP
GYGFLSENEDFAAACEAAGIAFIGPPASAIAAMGSKSAAKALMEKAGVPLVPGYHGDEQDPALLQQQADAIGYPVLIKAS
AGGGGKGMRIVEQAGDFSAALASCQREARASFGDDKVLVEKYLTRPRHVEIQVFADKLGGCVYLFERDCSVQRRHQKVLE
EAPAPHLPQATREAMGQAAVAAARAVGYVGAGTVEFIMDVDTGKFYFMEMNTRLQVEHPVTEMITGQDLVAWQLAVAAGG
ALPLAQEQLAMRGHAIEARIYAEDPDKGFLPSTGTLAHLATPAESAHVRIDTGVEQGDAISPFYDPMIAKLIVWGETREA
ALRQMDAALAQYRIVGLSSNVSFLRRIVNHPSFASGQVDTGLIARHHDALLPPPAAPTARQLALLALAEALAHPAAYPAP
AGWRLNGRLTRRFAFQRDDEDYGVELQYQDDGCVVRVGTESFHARASLAGNQLEAVLNGLRVKAVIVRHGARRALFEGGE
RLSVDFVDPYAYTELGVHGETHLKAPMPGRVVALLAEIGKKVAKGSPLLILEAMKMEHTITAPGDGVVQDFYFAAGEQVN
DGDELVDFAAE

Sequences:

>Translated_651_residues
MFNKILIANRGEIACRVIKTAKALGIATVAVYSDADANARFVKLADEAYRLGPAPAAESYLRADLILAIARQSGAQAVHP
GYGFLSENEDFAAACEAAGIAFIGPPASAIAAMGSKSAAKALMEKAGVPLVPGYHGDEQDPALLQQQADAIGYPVLIKAS
AGGGGKGMRIVEQAGDFSAALASCQREARASFGDDKVLVEKYLTRPRHVEIQVFADKLGGCVYLFERDCSVQRRHQKVLE
EAPAPHLPQATREAMGQAAVAAARAVGYVGAGTVEFIMDVDTGKFYFMEMNTRLQVEHPVTEMITGQDLVAWQLAVAAGG
ALPLAQEQLAMRGHAIEARIYAEDPDKGFLPSTGTLAHLATPAESAHVRIDTGVEQGDAISPFYDPMIAKLIVWGETREA
ALRQMDAALAQYRIVGLSSNVSFLRRIVNHPSFASGQVDTGLIARHHDALLPPPAAPTARQLALLALAEALAHPAAYPAP
AGWRLNGRLTRRFAFQRDDEDYGVELQYQDDGCVVRVGTESFHARASLAGNQLEAVLNGLRVKAVIVRHGARRALFEGGE
RLSVDFVDPYAYTELGVHGETHLKAPMPGRVVALLAEIGKKVAKGSPLLILEAMKMEHTITAPGDGVVQDFYFAAGEQVN
DGDELVDFAAE
>Mature_651_residues
MFNKILIANRGEIACRVIKTAKALGIATVAVYSDADANARFVKLADEAYRLGPAPAAESYLRADLILAIARQSGAQAVHP
GYGFLSENEDFAAACEAAGIAFIGPPASAIAAMGSKSAAKALMEKAGVPLVPGYHGDEQDPALLQQQADAIGYPVLIKAS
AGGGGKGMRIVEQAGDFSAALASCQREARASFGDDKVLVEKYLTRPRHVEIQVFADKLGGCVYLFERDCSVQRRHQKVLE
EAPAPHLPQATREAMGQAAVAAARAVGYVGAGTVEFIMDVDTGKFYFMEMNTRLQVEHPVTEMITGQDLVAWQLAVAAGG
ALPLAQEQLAMRGHAIEARIYAEDPDKGFLPSTGTLAHLATPAESAHVRIDTGVEQGDAISPFYDPMIAKLIVWGETREA
ALRQMDAALAQYRIVGLSSNVSFLRRIVNHPSFASGQVDTGLIARHHDALLPPPAAPTARQLALLALAEALAHPAAYPAP
AGWRLNGRLTRRFAFQRDDEDYGVELQYQDDGCVVRVGTESFHARASLAGNQLEAVLNGLRVKAVIVRHGARRALFEGGE
RLSVDFVDPYAYTELGVHGETHLKAPMPGRVVALLAEIGKKVAKGSPLLILEAMKMEHTITAPGDGVVQDFYFAAGEQVN
DGDELVDFAAE

Specific function: This protein carries two functions:biotin carboxyl carrier protein and biotin carboxyltransferase [H]

COG id: COG4770

COG function: function code I; Acetyl/propionyl-CoA carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=671, Percent_Identity=48.2861400894188, Blast_Score=629, Evalue=1e-180,
Organism=Homo sapiens, GI189095269, Length=683, Percent_Identity=41.5812591508053, Blast_Score=475, Evalue=1e-134,
Organism=Homo sapiens, GI65506442, Length=683, Percent_Identity=41.5812591508053, Blast_Score=475, Evalue=1e-134,
Organism=Homo sapiens, GI295821183, Length=667, Percent_Identity=41.3793103448276, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI106049528, Length=484, Percent_Identity=41.5289256198347, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI106049295, Length=484, Percent_Identity=41.5289256198347, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI106049292, Length=484, Percent_Identity=41.5289256198347, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI38679977, Length=718, Percent_Identity=32.033426183844, Blast_Score=286, Evalue=6e-77,
Organism=Homo sapiens, GI38679967, Length=718, Percent_Identity=32.033426183844, Blast_Score=286, Evalue=6e-77,
Organism=Homo sapiens, GI38679971, Length=715, Percent_Identity=32.1678321678322, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI38679974, Length=715, Percent_Identity=32.1678321678322, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI38679960, Length=718, Percent_Identity=32.033426183844, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI134142062, Length=504, Percent_Identity=34.9206349206349, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI18105007, Length=314, Percent_Identity=24.203821656051, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1789654, Length=439, Percent_Identity=50.5694760820046, Blast_Score=401, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI71987519, Length=673, Percent_Identity=47.6968796433878, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17567343, Length=679, Percent_Identity=42.2680412371134, Blast_Score=479, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI17562816, Length=466, Percent_Identity=43.7768240343348, Blast_Score=357, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI133931226, Length=684, Percent_Identity=27.7777777777778, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI71997168, Length=506, Percent_Identity=30.0395256916996, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71997163, Length=502, Percent_Identity=30.6772908366534, Blast_Score=204, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6319685, Length=493, Percent_Identity=42.1906693711968, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6319695, Length=453, Percent_Identity=44.3708609271523, Blast_Score=342, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6321376, Length=448, Percent_Identity=45.0892857142857, Blast_Score=337, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6324343, Length=708, Percent_Identity=31.4971751412429, Blast_Score=291, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6323863, Length=666, Percent_Identity=30.3303303303303, Blast_Score=263, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24651757, Length=676, Percent_Identity=48.3727810650888, Blast_Score=622, Evalue=1e-178,
Organism=Drosophila melanogaster, GI24651759, Length=636, Percent_Identity=47.4842767295598, Blast_Score=570, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281363050, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652224, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652222, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652212, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652220, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652210, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652214, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI19921944, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652218, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24652216, Length=483, Percent_Identity=42.8571428571429, Blast_Score=355, Evalue=7e-98,
Organism=Drosophila melanogaster, GI24586458, Length=510, Percent_Identity=32.9411764705882, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI161076409, Length=510, Percent_Identity=32.9411764705882, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI161076407, Length=510, Percent_Identity=32.9411764705882, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586460, Length=510, Percent_Identity=32.9411764705882, Blast_Score=247, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR001882
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14 [H]

Molecular weight: Translated: 69502; Mature: 69502

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKILIANRGEIACRVIKTAKALGIATVAVYSDADANARFVKLADEAYRLGPAPAAESY
CCCEEEEECCCCEEEHHHHHHHHHCEEEEEEEECCCCCCEEEEECHHHHHCCCCCHHHHH
LRADLILAIARQSGAQAVHPGYGFLSENEDFAAACEAAGIAFIGPPASAIAAMGSKSAAK
HHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHCCHHHHH
ALMEKAGVPLVPGYHGDEQDPALLQQQADAIGYPVLIKASAGGGGKGMRIVEQAGDFSAA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCHHHH
LASCQREARASFGDDKVLVEKYLTRPRHVEIQVFADKLGGCVYLFERDCSVQRRHQKVLE
HHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEEEHHCCEEEEEECCCCHHHHHHHHHH
EAPAPHLPQATREAMGQAAVAAARAVGYVGAGTVEFIMDVDTGKFYFMEMNTRLQVEHPV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCEEEECCCH
TEMITGQDLVAWQLAVAAGGALPLAQEQLAMRGHAIEARIYAEDPDKGFLPSTGTLAHLA
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEE
TPAESAHVRIDTGVEQGDAISPFYDPMIAKLIVWGETREAALRQMDAALAQYRIVGLSSN
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHEEECCCHHHHHHHHHHHHHHEEEEEECCC
VSFLRRIVNHPSFASGQVDTGLIARHHDALLPPPAAPTARQLALLALAEALAHPAAYPAP
HHHHHHHHCCCCCCCCCCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
AGWRLNGRLTRRFAFQRDDEDYGVELQYQDDGCVVRVGTESFHARASLAGNQLEAVLNGL
CCEEECCEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHCCHHHHHHHCCC
RVKAVIVRHGARRALFEGGERLSVDFVDPYAYTELGVHGETHLKAPMPGRVVALLAEIGK
EEEEEEECCCCHHHHHCCCCEEEEEEECCCHHHHCCCCCCCEECCCCCHHHHHHHHHHHH
KVAKGSPLLILEAMKMEHTITAPGDGVVQDFYFAAGEQVNDGDELVDFAAE
HHHCCCCEEEEEEECCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MFNKILIANRGEIACRVIKTAKALGIATVAVYSDADANARFVKLADEAYRLGPAPAAESY
CCCEEEEECCCCEEEHHHHHHHHHCEEEEEEEECCCCCCEEEEECHHHHHCCCCCHHHHH
LRADLILAIARQSGAQAVHPGYGFLSENEDFAAACEAAGIAFIGPPASAIAAMGSKSAAK
HHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHCCHHHHH
ALMEKAGVPLVPGYHGDEQDPALLQQQADAIGYPVLIKASAGGGGKGMRIVEQAGDFSAA
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHCCCHHHH
LASCQREARASFGDDKVLVEKYLTRPRHVEIQVFADKLGGCVYLFERDCSVQRRHQKVLE
HHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEEEEEHHCCEEEEEECCCCHHHHHHHHHH
EAPAPHLPQATREAMGQAAVAAARAVGYVGAGTVEFIMDVDTGKFYFMEMNTRLQVEHPV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCEEEECCCH
TEMITGQDLVAWQLAVAAGGALPLAQEQLAMRGHAIEARIYAEDPDKGFLPSTGTLAHLA
HHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCEEEEE
TPAESAHVRIDTGVEQGDAISPFYDPMIAKLIVWGETREAALRQMDAALAQYRIVGLSSN
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHHEEECCCHHHHHHHHHHHHHHEEEEEECCC
VSFLRRIVNHPSFASGQVDTGLIARHHDALLPPPAAPTARQLALLALAEALAHPAAYPAP
HHHHHHHHCCCCCCCCCCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
AGWRLNGRLTRRFAFQRDDEDYGVELQYQDDGCVVRVGTESFHARASLAGNQLEAVLNGL
CCEEECCEEEEEEECCCCCCCCCEEEEECCCCEEEEECCCCHHHHHHHCCHHHHHHHCCC
RVKAVIVRHGARRALFEGGERLSVDFVDPYAYTELGVHGETHLKAPMPGRVVALLAEIGK
EEEEEEECCCCHHHHHCCCCEEEEEEECCCHHHHCCCCCCCEECCCCCHHHHHHHHHHHH
KVAKGSPLLILEAMKMEHTITAPGDGVVQDFYFAAGEQVNDGDELVDFAAE
HHHCCCCEEEEEEECCCEEEECCCCCHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]