Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 34497154

GI number: 34497154

Start: 1837352

End: 1839886

Strand: Reverse

Name: cirA [H]

Synonym: CV_1699

Alternate gene names: 34497154

Gene position: 1839886-1837352 (Counterclockwise)

Preceding gene: 34497155

Following gene: 34497153

Centisome position: 38.73

GC content: 68.09

Gene sequence:

>2535_bases
TTGCCTTTTTCCGCCCTCGCCGCCGACGCCGGCGACAACTCGCTGGAACGCGTCACCGTCACCGGCTCCAATCTGCGCGC
CAGCGCCAAGGCCAAGACCAATCCGGTGCAGGTCCTCAGCGCCGCCGACATCGAGCGCAGCGGCAAGACCAGCCTGCCCG
ACGTGCTGCGCGCGCTGGCCGTCAACAGCGGCAACAGCTTCAACGAACAGTACACCGGCAGCTTCTCCGCCGGCACCGCC
GGCGTCTCGCTGCGCGGCCTGGGCCAGCGCAACACCCTGGTGCTGGTCAACGGCAAGCGCGTATCCAACTACGCCACCGC
CCAGGACCTGCAGGAAACCTTCGTCGACCTGAACTCGCTGCCGCTGAAAGCGGTGAAACGCATCGAAATCCTGAAGGACG
GCGCCTCCGCCATCTATGGCTCGGACGCCATCGCCGGCGTGGTCAACATCATCCTCTACCCGTCCTACCAGGGCCTGGAG
CTGGGCGCCGACATCGGCCGCGACACCAGCACCGGCCAGGACGAGCGCCGCATGAACCTGCTGGCCGGCAAAGGCGACCT
GGACAAGGACGGCTACAACGTCTGGTTCTCCTTCGACGCGCAAAAGCGCGACCGGCTGGACCAGAGCGGCGTGGACTGGC
TGAAGGACAACGACTTCCGCGGCCTGCCCGGCGGCAAGCTGGTGCGCACGCCGACCAACTACTACAACGGCAATCCGACC
CAGCGTTTCCCCCACGCCGCCGGACCGGCGCAGGACCTGGACTACGGCGCGGTCAATCCCGGCAAGAGCGGCCGCATCTG
GGCCTACAACCCGGCGCAGTACACCACGCTGATGCCGGGCATCGAGCGCTATCACGCGGCATTGCACGGCAGCTACCGGC
TGACCCCGGCGACCGAGGCTTACGCCGAATTCCTCTACGGCGCCAGCCACAGCGCCCAGATCTTCGGCCCGCCGCTATCC
ATCTCCAGCAGCCTGCGCGCCTGGGACTCCGCCTCGCAATCGCTGACGCCGGTCAGCAATGTGCTGCCGGCCGGCAACCC
CTCCAATCCCAACGCCTCGCCGACGCCGTTCACCGCCAACCTGTTCGACCTGGGCCAGCGCAACAAGACCGACAGCGTGT
CGTTCCGCCGCCTGCTGCTGGGCGTCAAGGGCAGCGGCGACGCCTGGGACTGGGACGTGTCCGGCCTGTATTCCGACAGC
CGCCTGCGCGAATACGCGTACAACTTCGTCAACCGCTACGCTTACGAGCAGCTGCTGGCCAACGGCGGCTACAACTTCAT
CGATCCCTCGCGCAACAGCGAGGCGGTGCGCGACAGCCTGCGCATCCGCACCATGCGCCCCGCCTGGTACCGCGTCGCCA
GCCTGGACGCCACCGCCAGCACCGAGCTGGCCCAGCTGCCGGCCGGCCCGGTGGGCTTCGCCGCCGGCTACCAGCTGCGG
CGCGAAATGATGAATTCCGGCACCTCGTCAGAAGTGGCCAGCGGCACGGAGCTGCGGCCGGCGCTGGACCTGATCCGCGG
CGGCCGCACCATACAGGCGGCTTACGGCGAGTTCAACGTGCCGATCAGCAAGACCCTCAGCCTCAACGCCGCCGCCCGCG
CCGACCACTACAGCGACTTCGGCAACGCCTTCTCGCCCAAGCTGGGCCTGCGCTACCAGCCGCTGCAAAGCCTGACGCTG
CGCGGCTCGGTGTCGCGCGGCTTCCGCGCGCCGTCGCTGCCGGAAATCACCAGCAGCACCGCGGTCAGCTACGGCTCGGT
GCAGGACCCGTACGATCCGCTGACGCCGAACCAGAACGTGTCCTTCACTCATCTGATCACGGCGAATCCGAATATCAAGC
CCGAGCGCTCGACCAACGCCAACCTGGGCCTGGTGCTCGCCCCGACCGCCGATACCAGCGTCAGCCTGGATTACTACCGC
ATCCGCCAGCGCGACGTGATCGGCCTGGAAGACGTGAGCGACATCGTGCGCCATCCGGACGCCTACCCCGGCGCCATCGT
CCGCGACGCCCAAGGCCGGCTGCAAACCATCACCCAGCGCTTCACCAATCTGGGCGGACGCGACACTTCCGGCTTCGACA
TCGAACTGCGACAGGGCTGGAAGCTGCCCGGCGGCAAGCTGACTCTGGCGGCGCAGTGGAGCCGGCTGCTGTCGTTCAGC
CAGCCGCTGCAGCAGGGTGGCGAGATGCAGGAAGGCGCCGGCAGCAACCTGCTGGGCGCGCTGCCGCGCTGGAAGGGCCA
GACCTCAGCCAATTGGGACGCCGGCGCCTGGTCGTCCACCCTCACCTGGTTCCATACCGATGGCTATGCCCAGACCGGCG
GCGATGCCACTCAGCAACGGGTCGACGGCCTGGACACCTTCAACCTGAGCGCCAGCTACGCCGGCATCAAGCGCGTCACG
CTGACCGCCGCCGTGCAAAACCTGACCAATCGCCGCCCGCCCTGGGACGCGAGCGCCAGCCATTACTACGACGCCACCCA
GTACGATCCGGGCGGCCGCGCCTTCACGCTGGGCGTGCGCTACAAGCTGGACTGA

Upstream 100 bases:

>100_bases
GGCTGACTCCCGCCGGACAGGCCCGCCGCTTCATTTCATAACCAAGAAAGTCTCCGTGATGATCAAACACACCCTGCTGC
TGGCCGGGCTGGGCGCCGCT

Downstream 100 bases:

>100_bases
CGCCCTTCTCAACGGCGGCGCCCAACGGCGCCGCCGTTCTTTTTCACGCTCCGCCGGCAAGAAAATACTAAGTAGAATCA
CGAAGCATGCATTAACCTTC

Product: tonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 844; Mature: 843

Protein sequence:

>844_residues
MPFSALAADAGDNSLERVTVTGSNLRASAKAKTNPVQVLSAADIERSGKTSLPDVLRALAVNSGNSFNEQYTGSFSAGTA
GVSLRGLGQRNTLVLVNGKRVSNYATAQDLQETFVDLNSLPLKAVKRIEILKDGASAIYGSDAIAGVVNIILYPSYQGLE
LGADIGRDTSTGQDERRMNLLAGKGDLDKDGYNVWFSFDAQKRDRLDQSGVDWLKDNDFRGLPGGKLVRTPTNYYNGNPT
QRFPHAAGPAQDLDYGAVNPGKSGRIWAYNPAQYTTLMPGIERYHAALHGSYRLTPATEAYAEFLYGASHSAQIFGPPLS
ISSSLRAWDSASQSLTPVSNVLPAGNPSNPNASPTPFTANLFDLGQRNKTDSVSFRRLLLGVKGSGDAWDWDVSGLYSDS
RLREYAYNFVNRYAYEQLLANGGYNFIDPSRNSEAVRDSLRIRTMRPAWYRVASLDATASTELAQLPAGPVGFAAGYQLR
REMMNSGTSSEVASGTELRPALDLIRGGRTIQAAYGEFNVPISKTLSLNAAARADHYSDFGNAFSPKLGLRYQPLQSLTL
RGSVSRGFRAPSLPEITSSTAVSYGSVQDPYDPLTPNQNVSFTHLITANPNIKPERSTNANLGLVLAPTADTSVSLDYYR
IRQRDVIGLEDVSDIVRHPDAYPGAIVRDAQGRLQTITQRFTNLGGRDTSGFDIELRQGWKLPGGKLTLAAQWSRLLSFS
QPLQQGGEMQEGAGSNLLGALPRWKGQTSANWDAGAWSSTLTWFHTDGYAQTGGDATQQRVDGLDTFNLSASYAGIKRVT
LTAAVQNLTNRRPPWDASASHYYDATQYDPGGRAFTLGVRYKLD

Sequences:

>Translated_844_residues
MPFSALAADAGDNSLERVTVTGSNLRASAKAKTNPVQVLSAADIERSGKTSLPDVLRALAVNSGNSFNEQYTGSFSAGTA
GVSLRGLGQRNTLVLVNGKRVSNYATAQDLQETFVDLNSLPLKAVKRIEILKDGASAIYGSDAIAGVVNIILYPSYQGLE
LGADIGRDTSTGQDERRMNLLAGKGDLDKDGYNVWFSFDAQKRDRLDQSGVDWLKDNDFRGLPGGKLVRTPTNYYNGNPT
QRFPHAAGPAQDLDYGAVNPGKSGRIWAYNPAQYTTLMPGIERYHAALHGSYRLTPATEAYAEFLYGASHSAQIFGPPLS
ISSSLRAWDSASQSLTPVSNVLPAGNPSNPNASPTPFTANLFDLGQRNKTDSVSFRRLLLGVKGSGDAWDWDVSGLYSDS
RLREYAYNFVNRYAYEQLLANGGYNFIDPSRNSEAVRDSLRIRTMRPAWYRVASLDATASTELAQLPAGPVGFAAGYQLR
REMMNSGTSSEVASGTELRPALDLIRGGRTIQAAYGEFNVPISKTLSLNAAARADHYSDFGNAFSPKLGLRYQPLQSLTL
RGSVSRGFRAPSLPEITSSTAVSYGSVQDPYDPLTPNQNVSFTHLITANPNIKPERSTNANLGLVLAPTADTSVSLDYYR
IRQRDVIGLEDVSDIVRHPDAYPGAIVRDAQGRLQTITQRFTNLGGRDTSGFDIELRQGWKLPGGKLTLAAQWSRLLSFS
QPLQQGGEMQEGAGSNLLGALPRWKGQTSANWDAGAWSSTLTWFHTDGYAQTGGDATQQRVDGLDTFNLSASYAGIKRVT
LTAAVQNLTNRRPPWDASASHYYDATQYDPGGRAFTLGVRYKLD
>Mature_843_residues
PFSALAADAGDNSLERVTVTGSNLRASAKAKTNPVQVLSAADIERSGKTSLPDVLRALAVNSGNSFNEQYTGSFSAGTAG
VSLRGLGQRNTLVLVNGKRVSNYATAQDLQETFVDLNSLPLKAVKRIEILKDGASAIYGSDAIAGVVNIILYPSYQGLEL
GADIGRDTSTGQDERRMNLLAGKGDLDKDGYNVWFSFDAQKRDRLDQSGVDWLKDNDFRGLPGGKLVRTPTNYYNGNPTQ
RFPHAAGPAQDLDYGAVNPGKSGRIWAYNPAQYTTLMPGIERYHAALHGSYRLTPATEAYAEFLYGASHSAQIFGPPLSI
SSSLRAWDSASQSLTPVSNVLPAGNPSNPNASPTPFTANLFDLGQRNKTDSVSFRRLLLGVKGSGDAWDWDVSGLYSDSR
LREYAYNFVNRYAYEQLLANGGYNFIDPSRNSEAVRDSLRIRTMRPAWYRVASLDATASTELAQLPAGPVGFAAGYQLRR
EMMNSGTSSEVASGTELRPALDLIRGGRTIQAAYGEFNVPISKTLSLNAAARADHYSDFGNAFSPKLGLRYQPLQSLTLR
GSVSRGFRAPSLPEITSSTAVSYGSVQDPYDPLTPNQNVSFTHLITANPNIKPERSTNANLGLVLAPTADTSVSLDYYRI
RQRDVIGLEDVSDIVRHPDAYPGAIVRDAQGRLQTITQRFTNLGGRDTSGFDIELRQGWKLPGGKLTLAAQWSRLLSFSQ
PLQQGGEMQEGAGSNLLGALPRWKGQTSANWDAGAWSSTLTWFHTDGYAQTGGDATQQRVDGLDTFNLSASYAGIKRVTL
TAAVQNLTNRRPPWDASASHYYDATQYDPGGRAFTLGVRYKLD

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=146, Percent_Identity=33.5616438356164, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1790405, Length=192, Percent_Identity=32.2916666666667, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 91486; Mature: 91355

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSALAADAGDNSLERVTVTGSNLRASAKAKTNPVQVLSAADIERSGKTSLPDVLRALA
CCCHHHCCCCCCCCCEEEEEECCCCEECCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHH
VNSGNSFNEQYTGSFSAGTAGVSLRGLGQRNTLVLVNGKRVSNYATAQDLQETFVDLNSL
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
PLKAVKRIEILKDGASAIYGSDAIAGVVNIILYPSYQGLELGADIGRDTSTGQDERRMNL
CHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHH
LAGKGDLDKDGYNVWFSFDAQKRDRLDQSGVDWLKDNDFRGLPGGKLVRTPTNYYNGNPT
EECCCCCCCCCCEEEEEECCHHHHCCCCCCCCHHCCCCCCCCCCCCEEECCCCCCCCCCC
QRFPHAAGPAQDLDYGAVNPGKSGRIWAYNPAQYTTLMPGIERYHAALHGSYRLTPATEA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHCCCEEECCHHHH
YAEFLYGASHSAQIFGPPLSISSSLRAWDSASQSLTPVSNVLPAGNPSNPNASPTPFTAN
HHHHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEECH
LFDLGQRNKTDSVSFRRLLLGVKGSGDAWDWDVSGLYSDSRLREYAYNFVNRYAYEQLLA
HHHCCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NGGYNFIDPSRNSEAVRDSLRIRTMRPAWYRVASLDATASTELAQLPAGPVGFAAGYQLR
CCCCCCCCCCCCHHHHHHHHHEEEECCHHEEEEECCCCCCCHHHHCCCCCCCHHHHHHHH
REMMNSGTSSEVASGTELRPALDLIRGGRTIQAAYGEFNVPISKTLSLNAAARADHYSDF
HHHHHCCCCHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHEEECCHHHHCCHHHHH
GNAFSPKLGLRYQPLQSLTLRGSVSRGFRAPSLPEITSSTAVSYGSVQDPYDPLTPNQNV
CCCCCCCCCCEECCHHHEEECCCHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
SFTHLITANPNIKPERSTNANLGLVLAPTADTSVSLDYYRIRQRDVIGLEDVSDIVRHPD
EEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHCCCCCCCHHHHHHHHHCCC
AYPGAIVRDAQGRLQTITQRFTNLGGRDTSGFDIELRQGWKLPGGKLTLAAQWSRLLSFS
CCCCCEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHH
QPLQQGGEMQEGAGSNLLGALPRWKGQTSANWDAGAWSSTLTWFHTDGYAQTGGDATQQR
HHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
VDGLDTFNLSASYAGIKRVTLTAAVQNLTNRRPPWDASASHYYDATQYDPGGRAFTLGVR
HCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEEEE
YKLD
EECC
>Mature Secondary Structure 
PFSALAADAGDNSLERVTVTGSNLRASAKAKTNPVQVLSAADIERSGKTSLPDVLRALA
CCHHHCCCCCCCCCEEEEEECCCCEECCCCCCCCEEEEEHHCCCCCCCCCHHHHHHHHH
VNSGNSFNEQYTGSFSAGTAGVSLRGLGQRNTLVLVNGKRVSNYATAQDLQETFVDLNSL
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCC
PLKAVKRIEILKDGASAIYGSDAIAGVVNIILYPSYQGLELGADIGRDTSTGQDERRMNL
CHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHHHHH
LAGKGDLDKDGYNVWFSFDAQKRDRLDQSGVDWLKDNDFRGLPGGKLVRTPTNYYNGNPT
EECCCCCCCCCCEEEEEECCHHHHCCCCCCCCHHCCCCCCCCCCCCEEECCCCCCCCCCC
QRFPHAAGPAQDLDYGAVNPGKSGRIWAYNPAQYTTLMPGIERYHAALHGSYRLTPATEA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHCCHHHHHHHHCCCEEECCHHHH
YAEFLYGASHSAQIFGPPLSISSSLRAWDSASQSLTPVSNVLPAGNPSNPNASPTPFTAN
HHHHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEECH
LFDLGQRNKTDSVSFRRLLLGVKGSGDAWDWDVSGLYSDSRLREYAYNFVNRYAYEQLLA
HHHCCCCCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NGGYNFIDPSRNSEAVRDSLRIRTMRPAWYRVASLDATASTELAQLPAGPVGFAAGYQLR
CCCCCCCCCCCCHHHHHHHHHEEEECCHHEEEEECCCCCCCHHHHCCCCCCCHHHHHHHH
REMMNSGTSSEVASGTELRPALDLIRGGRTIQAAYGEFNVPISKTLSLNAAARADHYSDF
HHHHHCCCCHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCHHHEEECCHHHHCCHHHHH
GNAFSPKLGLRYQPLQSLTLRGSVSRGFRAPSLPEITSSTAVSYGSVQDPYDPLTPNQNV
CCCCCCCCCCEECCHHHEEECCCHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCC
SFTHLITANPNIKPERSTNANLGLVLAPTADTSVSLDYYRIRQRDVIGLEDVSDIVRHPD
EEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHCCCCCCCHHHHHHHHHCCC
AYPGAIVRDAQGRLQTITQRFTNLGGRDTSGFDIELRQGWKLPGGKLTLAAQWSRLLSFS
CCCCCEEECCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHH
QPLQQGGEMQEGAGSNLLGALPRWKGQTSANWDAGAWSSTLTWFHTDGYAQTGGDATQQR
HHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHH
VDGLDTFNLSASYAGIKRVTLTAAVQNLTNRRPPWDASASHYYDATQYDPGGRAFTLGVR
HCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCEEEEEEE
YKLD
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]