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The map label for this gene is acrE [C]

Identifier: 34497082

GI number: 34497082

Start: 1764256

End: 1765362

Strand: Reverse

Name: acrE [C]

Synonym: CV_1627

Alternate gene names: 34497082

Gene position: 1765362-1764256 (Counterclockwise)

Preceding gene: 34497083

Following gene: 34497081

Centisome position: 37.16

GC content: 67.21

Gene sequence:

>1107_bases
ATGACCAAGCGAATGTTGATCATGCTGGGCTGCGTGCTGGCGCTGGTGGTGGCGCTGGGCGTGGGCTTTTTCCTCCACAT
CCAGAAGCTGATCGCCAGCTCGCCCAAGCCGGGGCCGCAGACGGTGTCCACCGCCGTGGCCAAGATGCAGGAATGGCAGC
CGCAGCTGGGTTCGGTGGGCACGCTGTCCGCCGTGCACGGCGTGGACGTCAGCAGCGAGGTGGCCGGCCTGGTGCGCAGC
CTGCACTTCAAGTCCGGCCAGGACGTGAAGGCCGGCGAGGTGCTGGTGCAGCTGAACGCCGACGCCGACGTCGCCCAGCT
GCGCGCGCTGCAGGCCGCCGCCGAACTGGCCGCCACCACGCTGAAGCGCGACCGCGCCCAGCTGGCGGTGCAGGGCGTCA
GCCAGGCCCAAGTGGACGCCGACGAAGCCGACCTGAAGAGCAAGAAGGCCCAGGTGGCGCAACAGGAGGCGGTGGTGGCG
AAAAAAACGATACGCGCGCCGTTCGCCGGCCGCGTCGGCATCACCGCGGTCAATCCCGGCCAGTACCTGAATCCGGGCGA
CAAGATCGTCACGCTGCAGACCATAGACCCGGTCTACATCGACTTCTACCTGCCCCAGCGGCAGATCGCGCAAATCCGCC
TGGGCCAGCAGGTCAAGGTGAAGAGCGACGCCTTCGGAACCGAGCCCTTCCACGGCCGGATCAACGCGATCAGTCCCAAG
ATCGACCCGGCCACCCGCAACGTCCAGGTGCAGGCGACCATCGCCAACCCCAAACGCCTGCTGCTGCCCGGCATGTTCGG
CAACGCCACCATCGACGTGGGCAGCAAGCAGAACCGCCTGACGCTGCCGCAAACCGCGATCACCTACAACCCGTACGGCT
CCACCGTGTTCCTCGTCAAGCAGGGCAAGAACGGGCCTGAAGCGCAGCAGGCCTTCGTCACCACCGGCGACACCCGCGGC
GACCAGGTGGCGATCACCGGCGGCCTGAAGGAAGGCCAGGAAGTGGTGACCAGCGGCCAGCTGAAGCTGAAGACCGGCAC
GCCGATCGCGGTCAACAACTCGGTGCGTCCGTCCGACAACCCGAGTCCGACGCCGCAAGAACACTGA

Upstream 100 bases:

>100_bases
CAACAGCCCGCGGCCGCCAACTGAGCGGGCAAGACACACACATCGCCCGCCGGCGACGGCGGGCCAGCCAATTCGAATCG
CCATATAGAGAAGACGAATC

Downstream 100 bases:

>100_bases
GGCCGCGCCATGAACTTCACCGACATCTTCATCAAGCGGCCGGTGCTGGCCACGACCATCAGCCTGCTGATCGTCGTGCT
CGGCCTGCGCTCGCTGTTCG

Product: acriflavin resistance protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MTKRMLIMLGCVLALVVALGVGFFLHIQKLIASSPKPGPQTVSTAVAKMQEWQPQLGSVGTLSAVHGVDVSSEVAGLVRS
LHFKSGQDVKAGEVLVQLNADADVAQLRALQAAAELAATTLKRDRAQLAVQGVSQAQVDADEADLKSKKAQVAQQEAVVA
KKTIRAPFAGRVGITAVNPGQYLNPGDKIVTLQTIDPVYIDFYLPQRQIAQIRLGQQVKVKSDAFGTEPFHGRINAISPK
IDPATRNVQVQATIANPKRLLLPGMFGNATIDVGSKQNRLTLPQTAITYNPYGSTVFLVKQGKNGPEAQQAFVTTGDTRG
DQVAITGGLKEGQEVVTSGQLKLKTGTPIAVNNSVRPSDNPSPTPQEH

Sequences:

>Translated_368_residues
MTKRMLIMLGCVLALVVALGVGFFLHIQKLIASSPKPGPQTVSTAVAKMQEWQPQLGSVGTLSAVHGVDVSSEVAGLVRS
LHFKSGQDVKAGEVLVQLNADADVAQLRALQAAAELAATTLKRDRAQLAVQGVSQAQVDADEADLKSKKAQVAQQEAVVA
KKTIRAPFAGRVGITAVNPGQYLNPGDKIVTLQTIDPVYIDFYLPQRQIAQIRLGQQVKVKSDAFGTEPFHGRINAISPK
IDPATRNVQVQATIANPKRLLLPGMFGNATIDVGSKQNRLTLPQTAITYNPYGSTVFLVKQGKNGPEAQQAFVTTGDTRG
DQVAITGGLKEGQEVVTSGQLKLKTGTPIAVNNSVRPSDNPSPTPQEH
>Mature_367_residues
TKRMLIMLGCVLALVVALGVGFFLHIQKLIASSPKPGPQTVSTAVAKMQEWQPQLGSVGTLSAVHGVDVSSEVAGLVRSL
HFKSGQDVKAGEVLVQLNADADVAQLRALQAAAELAATTLKRDRAQLAVQGVSQAQVDADEADLKSKKAQVAQQEAVVAK
KTIRAPFAGRVGITAVNPGQYLNPGDKIVTLQTIDPVYIDFYLPQRQIAQIRLGQQVKVKSDAFGTEPFHGRINAISPKI
DPATRNVQVQATIANPKRLLLPGMFGNATIDVGSKQNRLTLPQTAITYNPYGSTVFLVKQGKNGPEAQQAFVTTGDTRGD
QVAITGGLKEGQEVVTSGQLKLKTGTPIAVNNSVRPSDNPSPTPQEH

Specific function: May Affect Specific Membrane Functions, Such As Septum Formation During Cell Division, And Cell Membrane Permeability. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=331, Percent_Identity=28.3987915407855, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789929, Length=326, Percent_Identity=28.2208588957055, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87082036, Length=322, Percent_Identity=28.8819875776398, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786668, Length=318, Percent_Identity=28.3018867924528, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081796, Length=369, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39071; Mature: 38940

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRMLIMLGCVLALVVALGVGFFLHIQKLIASSPKPGPQTVSTAVAKMQEWQPQLGSVG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
TLSAVHGVDVSSEVAGLVRSLHFKSGQDVKAGEVLVQLNADADVAQLRALQAAAELAATT
CCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LKRDRAQLAVQGVSQAQVDADEADLKSKKAQVAQQEAVVAKKTIRAPFAGRVGITAVNPG
HHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
QYLNPGDKIVTLQTIDPVYIDFYLPQRQIAQIRLGQQVKVKSDAFGTEPFHGRINAISPK
CCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCEEEECCCCCCCCCCCCCEEECCCC
IDPATRNVQVQATIANPKRLLLPGMFGNATIDVGSKQNRLTLPQTAITYNPYGSTVFLVK
CCCCCCCEEEEEEECCCCEEEECCCCCCEEEECCCCCCCEECCCEEEEECCCCCEEEEEE
QGKNGPEAQQAFVTTGDTRGDQVAITGGLKEGQEVVTSGQLKLKTGTPIAVNNSVRPSDN
CCCCCCCHHEEEEEECCCCCCEEEEECCCCCCHHHHHCCCEEEECCCCEEECCCCCCCCC
PSPTPQEH
CCCCCCCC
>Mature Secondary Structure 
TKRMLIMLGCVLALVVALGVGFFLHIQKLIASSPKPGPQTVSTAVAKMQEWQPQLGSVG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
TLSAVHGVDVSSEVAGLVRSLHFKSGQDVKAGEVLVQLNADADVAQLRALQAAAELAATT
CCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LKRDRAQLAVQGVSQAQVDADEADLKSKKAQVAQQEAVVAKKTIRAPFAGRVGITAVNPG
HHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
QYLNPGDKIVTLQTIDPVYIDFYLPQRQIAQIRLGQQVKVKSDAFGTEPFHGRINAISPK
CCCCCCCCEEEEEECCCEEEEEECCHHHHHHHHCCCEEEECCCCCCCCCCCCCEEECCCC
IDPATRNVQVQATIANPKRLLLPGMFGNATIDVGSKQNRLTLPQTAITYNPYGSTVFLVK
CCCCCCCEEEEEEECCCCEEEECCCCCCEEEECCCCCCCEECCCEEEEECCCCCEEEEEE
QGKNGPEAQQAFVTTGDTRGDQVAITGGLKEGQEVVTSGQLKLKTGTPIAVNNSVRPSDN
CCCCCCCHHEEEEEECCCCCCEEEEECCCCCCHHHHHCCCEEEECCCCEEECCCCCCCCC
PSPTPQEH
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]