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The map label for this gene is putA [H]

Identifier: 34496993

GI number: 34496993

Start: 1652789

End: 1656382

Strand: Direct

Name: putA [H]

Synonym: CV_1538

Alternate gene names: 34496993

Gene position: 1652789-1656382 (Clockwise)

Preceding gene: 34496992

Following gene: 34496994

Centisome position: 34.79

GC content: 66.86

Gene sequence:

>3594_bases
ATGCAATTCGAATCCTTTGCTCATCAGCAGTCCGCTCTGCGCGATGCGATCACCGCCGCTTACCGGCGCGATGAACGCGA
GTGCGTGCAGGCTTTGTTGCCTCAGGCGGCGATGAGTCCCGAGCAAGTCGCATCAGTGCAAGACCTTGCCCGTCGGCTGG
TGACCGAGGTGCGCCGCGAGCGCACCCGTTCCAGCGGCGTGGACGCGCTGATGCACGAGTTCTCGTTGGACAGCAGCGAA
GGGATCGCCCTGATGTGTCTGGCGGAGGCGCTGCTGCGCATCCCCGACCGCGAGACGGCCGACAAGCTGATCCGCGACAA
GATTTCCCGCGGCGACTGGAAGGCCCATTTGGGCAACAGTTCGTCGCTGTTCGTCAACGCGGCCGCTTGGGGCCTGCTGG
TGACCGGCAAGCTGGTTTCCTCTCATAGCGCCAACGGCCTGTCGGCGGCGATGACGCGCCTGATCGCCAAAGGCGGCGAG
CCGCTGATCCGCAAGGGCGTCGACATGGCGATGCGCATGCTGGGCAAGCAGTTCGTCACCGGCGAGACGATCGAGGAAGC
GCTGGCCAACGGCCGCGAACGCGAAGCGCGCGGTTACCGCTTCAGCTACGACATGCTGGGCGAAGCGGCGATGACCGAAG
CCGACGCCCAACGCTACCTGAAGGACTACGTCACCGCCATCCATGCGATCGGCAAGGAGTCGAACGGCCGCGGCATCTAT
GACGGCCCCGGCATCTCGGTGAAGCTGTCCGCGATCCACCCGCGCTATGCCCGCCTGAAGCATGAACGCATGATGACCGA
GCTGCTGCCTCGACTGAAGGCGCTGTTCCTGTTGGCCAAGCAATACAATATCGGCCTGAACATCGACGCCGAGGAGGCCG
ACCGCCTGGAGATCTCGATGGACCTGGTCGAAGCGCTGGCCAACGATGCGGACCTGAACGGCTTCGAAGGCATCGGCATC
GTGGTGCAGGCCTACCAGAAGCGCTGTCCCTTCGTGATCGATTTCCTGATCGACCTGGCGCGCCGCACCGGCCACCGCTT
CATGGTGCGGCTGGTGAAGGGCGCCTACTGGGACGCCGAGATCAAGCGCGCCCAGGTGGACGGCCTGCCTGGCTATCCGG
TGTATACGCGCAAGGTGTACACCGATGTGTCCTACCTTGCCTGCGCCAAGAAGCTGCTGGCCGCCCAGGACGCGATCTAC
CCGCAGTTCGCCACGCACAACGCCTACAGCCTGTCGGCGATTTACAACCTGGCCGCCGGCAAGGATTACGAGTTCCAGTG
CCTGCACGGCATGGGCGAGACCCTGTACGACCAGGTAGTGGGCAAGGACAAGCTGGGCAAGGCTTGCCGCATCTACGCGC
CGGTCGGCTCGCATGAGACGCTGCTAGCCTACCTGGTGCGCCGCCTGCTGGAAAACGGCGCCAACTCCTCCTTCGTCAAC
CGCATCGTCGACGAAAACGTGTCCATCGACGAACTGGTGACCGATCCGGTGGCCGAGGCCGCCGGCTTTTCCGGCATGCC
GCACAGCAAGATTCCGCTGCCTGAGGCGCTGTACGGCGAAGGCCGCCGCAATTCCAAAGGCCTGGACCTGTCCAGCGAGC
ACGTGCTGGCCACGTTGCAGCTGGGCCTGCAGGCGTCCGAGCAGCAGCGTTGGGCCGCCTTCCCCATGCTGGGAGATGGC
GATGTCACCGACGGCGAGCTGCAGGAAGTGCGCAATCCGGCCGACCACAGCGATGTGGTGGGCAAGGTGATAGAGGCCAG
CGCCGCCGACGTCGAGCGCGCGCTGGCCCTATCGGCCGGCATCGCCGCCGCCTGGGCCGCGACGCCGGTAGCCGAGCGCG
CGGCCAGCATCCGCCGCATGGCCGACCTGATGGAGGCGCACATGCCGGCGCTGATGGGCCTGGCGGTGCGCGAGGCGGGC
AAGACGCTGAACAACGCCATCGCCGAAGTGCGCGAGGCGGTGGATTTCTGCCGCTACTACGCCGCGCAGATCGTGTCTGA
GTTCGACAACGCCAGCCACCGGCCGCTGGGTCCTGTGGTGTGCATCAGCCCGTGGAACTTCCCGCTGGCCATTTTCATCG
GCGAAGTCGTCGCGTCTTTGGCCGCCGGCAATACTGTACTGGCCAAGCCGGCCGAGCAGACCAGCCTGATCGCCGCCTAC
GCGGTGCGCCTGCTGCACGAGGCGGGCATCCCGCGCGCGGCGCTGCAGTTCCTGCCGGGCCGCGGCGAGGTGGTCGGCGC
CGCGCTGACCGGCGACGCGCGCATCCAGGGCGTGATCTTCACCGGTTCCACCGAGGTGGCGCAGATCATCAACCGCACGC
TGGCAAAACGCCAAGACGATCCGGTGCTGGTGGCGGAAACCGGCGGCATGAACGCGATGATCGTCGACAGCTCGGCGCTG
CCGGAACAGGTGGTCACCGATGTGCTGAGCTCTGCCTTCGATTCCGCCGGCCAGCGTTGCTCGGCGCTGCGGGTGCTGTA
CCTGCAGAACGACATCGCCGACAAGGTGATCGCGATGATCAAGGGGGCGATGGATGAGCTGACCATCGGCAATCCGGCCA
AGCTGACCACCGACGTCGGTCCGGTGATCGACGCCGAGGCCCAGGCCGGCCTGCTCGCCCACATCGCCAGGATGAAGAAC
TCCGCCCGCGCGATGCACCAGACCAAGCTGTCCGCGGCGTGCGAGCAGGGCACTTTCGTCGCGCCGACGCTGTTCGAGAT
CGACAATCTGTCGGAGCTCAAGCGCGAAGTGTTCGGCCCGGTGCTGCACGTGCTGCGCTATGCCGCGTCGGATCTGGACA
AGGTGGTGGCCGAGATCAACGCCACCGGCTATGGCCTGACCCACGGCATCCACAGCCGCATCGACGAAACCATCGCCGAC
ATCTGCGGCAAGATCAAAGTGGGCAATATCTACGTCAACCGCAACATCGTCGGCGCGGTGGTCGGGGTGCAGCCCTTCGG
CGGCGAGGGCAAGTCCGGCACCGGTCCCAAGGCAGGCGGTCCGTACTACCTGTACCGCCTGACCCGTGCCGCCTGGCAGC
CGAAGCTGGCCGCCGTGCCGGCGGCGGCCGATTTGTCCGCGCTGGACGCGCTGGCGGCCGCGGCCAAGGCGCAGAGCCTG
GCGCTGGACGGCGCGATCGCCGCCGCGCGCAAGGAAAGCCCGCTGACGCATAGCGTGGCGTTGCCGGGGCCGACCGGAGA
AAACAACTTGCTGTCCTTCGCCGGCCGCGGCCGCATAGGCTGCGTCGCCGACGACGCGCAGGCGCTGGCCGAACAGCTGG
CCGCGGCCTTCGCCGCCGGCAACCGCGCGGTGCTGGCCGATAACGAGCTGGGACGCAAGTTCGCGTCCGCCTTGAACGGC
CATGTGTCGCTGGCTGCCGACGTGCTGGAAGCGGATGTCGATGCGGTGTTGTACGCCGGCGCCAAGGCCGAGGAGGCACG
GCGCGAGCTGGCCGCCCGCGACGGCGCGCTGGTTCCGCTGATCCTGCGCGGCGAAAATGGCTACAATGTGCATCGGCTGG
TGGTCGAGCGCGCGCTTAGCGTCAATACCACGGCGGCCGGCGGAAACGCCAGCCTGATGAGCATGACCGAATGA

Upstream 100 bases:

>100_bases
AGAATATTTTATATTGTCGAACAGAATAGCCATCTCTTGTATACAATAGGCAGCTTACCCGGACGCGAGGCCGGGGCTGC
AAACAATATCGGAGAAACCC

Downstream 100 bases:

>100_bases
TCAACTTGCCAGCCTCTGGCCGCATTGGAATAATGCGGCCAGAGTTTTTACTTTAAGAGCAAGACTGGGATCCGGCACAA
GCCGGTTATGTAGAAGCGCG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1197; Mature: 1197

Protein sequence:

>1197_residues
MQFESFAHQQSALRDAITAAYRRDERECVQALLPQAAMSPEQVASVQDLARRLVTEVRRERTRSSGVDALMHEFSLDSSE
GIALMCLAEALLRIPDRETADKLIRDKISRGDWKAHLGNSSSLFVNAAAWGLLVTGKLVSSHSANGLSAAMTRLIAKGGE
PLIRKGVDMAMRMLGKQFVTGETIEEALANGREREARGYRFSYDMLGEAAMTEADAQRYLKDYVTAIHAIGKESNGRGIY
DGPGISVKLSAIHPRYARLKHERMMTELLPRLKALFLLAKQYNIGLNIDAEEADRLEISMDLVEALANDADLNGFEGIGI
VVQAYQKRCPFVIDFLIDLARRTGHRFMVRLVKGAYWDAEIKRAQVDGLPGYPVYTRKVYTDVSYLACAKKLLAAQDAIY
PQFATHNAYSLSAIYNLAAGKDYEFQCLHGMGETLYDQVVGKDKLGKACRIYAPVGSHETLLAYLVRRLLENGANSSFVN
RIVDENVSIDELVTDPVAEAAGFSGMPHSKIPLPEALYGEGRRNSKGLDLSSEHVLATLQLGLQASEQQRWAAFPMLGDG
DVTDGELQEVRNPADHSDVVGKVIEASAADVERALALSAGIAAAWAATPVAERAASIRRMADLMEAHMPALMGLAVREAG
KTLNNAIAEVREAVDFCRYYAAQIVSEFDNASHRPLGPVVCISPWNFPLAIFIGEVVASLAAGNTVLAKPAEQTSLIAAY
AVRLLHEAGIPRAALQFLPGRGEVVGAALTGDARIQGVIFTGSTEVAQIINRTLAKRQDDPVLVAETGGMNAMIVDSSAL
PEQVVTDVLSSAFDSAGQRCSALRVLYLQNDIADKVIAMIKGAMDELTIGNPAKLTTDVGPVIDAEAQAGLLAHIARMKN
SARAMHQTKLSAACEQGTFVAPTLFEIDNLSELKREVFGPVLHVLRYAASDLDKVVAEINATGYGLTHGIHSRIDETIAD
ICGKIKVGNIYVNRNIVGAVVGVQPFGGEGKSGTGPKAGGPYYLYRLTRAAWQPKLAAVPAAADLSALDALAAAAKAQSL
ALDGAIAAARKESPLTHSVALPGPTGENNLLSFAGRGRIGCVADDAQALAEQLAAAFAAGNRAVLADNELGRKFASALNG
HVSLAADVLEADVDAVLYAGAKAEEARRELAARDGALVPLILRGENGYNVHRLVVERALSVNTTAAGGNASLMSMTE

Sequences:

>Translated_1197_residues
MQFESFAHQQSALRDAITAAYRRDERECVQALLPQAAMSPEQVASVQDLARRLVTEVRRERTRSSGVDALMHEFSLDSSE
GIALMCLAEALLRIPDRETADKLIRDKISRGDWKAHLGNSSSLFVNAAAWGLLVTGKLVSSHSANGLSAAMTRLIAKGGE
PLIRKGVDMAMRMLGKQFVTGETIEEALANGREREARGYRFSYDMLGEAAMTEADAQRYLKDYVTAIHAIGKESNGRGIY
DGPGISVKLSAIHPRYARLKHERMMTELLPRLKALFLLAKQYNIGLNIDAEEADRLEISMDLVEALANDADLNGFEGIGI
VVQAYQKRCPFVIDFLIDLARRTGHRFMVRLVKGAYWDAEIKRAQVDGLPGYPVYTRKVYTDVSYLACAKKLLAAQDAIY
PQFATHNAYSLSAIYNLAAGKDYEFQCLHGMGETLYDQVVGKDKLGKACRIYAPVGSHETLLAYLVRRLLENGANSSFVN
RIVDENVSIDELVTDPVAEAAGFSGMPHSKIPLPEALYGEGRRNSKGLDLSSEHVLATLQLGLQASEQQRWAAFPMLGDG
DVTDGELQEVRNPADHSDVVGKVIEASAADVERALALSAGIAAAWAATPVAERAASIRRMADLMEAHMPALMGLAVREAG
KTLNNAIAEVREAVDFCRYYAAQIVSEFDNASHRPLGPVVCISPWNFPLAIFIGEVVASLAAGNTVLAKPAEQTSLIAAY
AVRLLHEAGIPRAALQFLPGRGEVVGAALTGDARIQGVIFTGSTEVAQIINRTLAKRQDDPVLVAETGGMNAMIVDSSAL
PEQVVTDVLSSAFDSAGQRCSALRVLYLQNDIADKVIAMIKGAMDELTIGNPAKLTTDVGPVIDAEAQAGLLAHIARMKN
SARAMHQTKLSAACEQGTFVAPTLFEIDNLSELKREVFGPVLHVLRYAASDLDKVVAEINATGYGLTHGIHSRIDETIAD
ICGKIKVGNIYVNRNIVGAVVGVQPFGGEGKSGTGPKAGGPYYLYRLTRAAWQPKLAAVPAAADLSALDALAAAAKAQSL
ALDGAIAAARKESPLTHSVALPGPTGENNLLSFAGRGRIGCVADDAQALAEQLAAAFAAGNRAVLADNELGRKFASALNG
HVSLAADVLEADVDAVLYAGAKAEEARRELAARDGALVPLILRGENGYNVHRLVVERALSVNTTAAGGNASLMSMTE
>Mature_1197_residues
MQFESFAHQQSALRDAITAAYRRDERECVQALLPQAAMSPEQVASVQDLARRLVTEVRRERTRSSGVDALMHEFSLDSSE
GIALMCLAEALLRIPDRETADKLIRDKISRGDWKAHLGNSSSLFVNAAAWGLLVTGKLVSSHSANGLSAAMTRLIAKGGE
PLIRKGVDMAMRMLGKQFVTGETIEEALANGREREARGYRFSYDMLGEAAMTEADAQRYLKDYVTAIHAIGKESNGRGIY
DGPGISVKLSAIHPRYARLKHERMMTELLPRLKALFLLAKQYNIGLNIDAEEADRLEISMDLVEALANDADLNGFEGIGI
VVQAYQKRCPFVIDFLIDLARRTGHRFMVRLVKGAYWDAEIKRAQVDGLPGYPVYTRKVYTDVSYLACAKKLLAAQDAIY
PQFATHNAYSLSAIYNLAAGKDYEFQCLHGMGETLYDQVVGKDKLGKACRIYAPVGSHETLLAYLVRRLLENGANSSFVN
RIVDENVSIDELVTDPVAEAAGFSGMPHSKIPLPEALYGEGRRNSKGLDLSSEHVLATLQLGLQASEQQRWAAFPMLGDG
DVTDGELQEVRNPADHSDVVGKVIEASAADVERALALSAGIAAAWAATPVAERAASIRRMADLMEAHMPALMGLAVREAG
KTLNNAIAEVREAVDFCRYYAAQIVSEFDNASHRPLGPVVCISPWNFPLAIFIGEVVASLAAGNTVLAKPAEQTSLIAAY
AVRLLHEAGIPRAALQFLPGRGEVVGAALTGDARIQGVIFTGSTEVAQIINRTLAKRQDDPVLVAETGGMNAMIVDSSAL
PEQVVTDVLSSAFDSAGQRCSALRVLYLQNDIADKVIAMIKGAMDELTIGNPAKLTTDVGPVIDAEAQAGLLAHIARMKN
SARAMHQTKLSAACEQGTFVAPTLFEIDNLSELKREVFGPVLHVLRYAASDLDKVVAEINATGYGLTHGIHSRIDETIAD
ICGKIKVGNIYVNRNIVGAVVGVQPFGGEGKSGTGPKAGGPYYLYRLTRAAWQPKLAAVPAAADLSALDALAAAAKAQSL
ALDGAIAAARKESPLTHSVALPGPTGENNLLSFAGRGRIGCVADDAQALAEQLAAAFAAGNRAVLADNELGRKFASALNG
HVSLAADVLEADVDAVLYAGAKAEEARRELAARDGALVPLILRGENGYNVHRLVVERALSVNTTAAGGNASLMSMTE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=525, Percent_Identity=31.047619047619, Blast_Score=200, Evalue=6e-51,
Organism=Homo sapiens, GI25777734, Length=525, Percent_Identity=31.047619047619, Blast_Score=200, Evalue=6e-51,
Organism=Homo sapiens, GI238859541, Length=483, Percent_Identity=31.6770186335404, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI21361176, Length=457, Percent_Identity=30.8533916849015, Blast_Score=187, Evalue=6e-47,
Organism=Homo sapiens, GI153266822, Length=446, Percent_Identity=28.6995515695067, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI25777724, Length=459, Percent_Identity=28.322440087146, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI25777730, Length=447, Percent_Identity=30.2013422818792, Blast_Score=174, Evalue=5e-43,
Organism=Homo sapiens, GI21614513, Length=419, Percent_Identity=29.5942720763723, Blast_Score=170, Evalue=9e-42,
Organism=Homo sapiens, GI25777732, Length=446, Percent_Identity=28.47533632287, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI25777728, Length=410, Percent_Identity=28.2926829268293, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI238814322, Length=460, Percent_Identity=27.8260869565217, Blast_Score=153, Evalue=8e-37,
Organism=Homo sapiens, GI310128103, Length=469, Percent_Identity=27.5053304904051, Blast_Score=147, Evalue=8e-35,
Organism=Homo sapiens, GI310128093, Length=456, Percent_Identity=27.8508771929825, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI188035924, Length=467, Percent_Identity=27.4089935760171, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI12007648, Length=439, Percent_Identity=25.0569476082005, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI25777726, Length=459, Percent_Identity=25.0544662309368, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI4507229, Length=414, Percent_Identity=27.536231884058, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI11095441, Length=426, Percent_Identity=26.7605633802817, Blast_Score=124, Evalue=4e-28,
Organism=Homo sapiens, GI310128091, Length=383, Percent_Identity=28.4595300261097, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI25777721, Length=427, Percent_Identity=26.6978922716628, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=24.4060475161987, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI25952152, Length=433, Percent_Identity=24.7113163972286, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310128087, Length=280, Percent_Identity=29.2857142857143, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI206597441, Length=331, Percent_Identity=27.190332326284, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI206597439, Length=331, Percent_Identity=27.190332326284, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI22907049, Length=331, Percent_Identity=27.190332326284, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI71773324, Length=379, Percent_Identity=24.5382585751979, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI4502043, Length=336, Percent_Identity=24.4047619047619, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI238814371, Length=336, Percent_Identity=24.4047619047619, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI310128089, Length=321, Percent_Identity=28.0373831775701, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI73466520, Length=330, Percent_Identity=24.8484848484848, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI4557303, Length=330, Percent_Identity=24.8484848484848, Blast_Score=88, Evalue=5e-17,
Organism=Homo sapiens, GI310128095, Length=309, Percent_Identity=27.831715210356, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI73695881, Length=323, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI73695879, Length=323, Percent_Identity=23.5294117647059, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI310128099, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128101, Length=229, Percent_Identity=27.9475982532751, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128097, Length=253, Percent_Identity=28.8537549407115, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI301500698, Length=430, Percent_Identity=21.1627906976744, Blast_Score=71, Evalue=5e-12,
Organism=Escherichia coli, GI1787250, Length=1245, Percent_Identity=58.8755020080321, Blast_Score=1389, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=451, Percent_Identity=30.3769401330377, Blast_Score=170, Evalue=6e-43,
Organism=Escherichia coli, GI87081896, Length=460, Percent_Identity=30.2173913043478, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1788042, Length=455, Percent_Identity=29.8901098901099, Blast_Score=160, Evalue=4e-40,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=29.2841648590022, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787558, Length=437, Percent_Identity=29.0617848970252, Blast_Score=157, Evalue=5e-39,
Organism=Escherichia coli, GI1787715, Length=455, Percent_Identity=30.1098901098901, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI87082295, Length=460, Percent_Identity=28.0434782608696, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI1786504, Length=454, Percent_Identity=27.0925110132159, Blast_Score=139, Evalue=1e-33,
Organism=Escherichia coli, GI87081926, Length=426, Percent_Identity=27.4647887323944, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17534447, Length=483, Percent_Identity=32.712215320911, Blast_Score=199, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI25144435, Length=453, Percent_Identity=30.242825607064, Blast_Score=176, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI115532534, Length=345, Percent_Identity=36.231884057971, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17562198, Length=456, Percent_Identity=29.3859649122807, Blast_Score=171, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=404, Percent_Identity=30.6930693069307, Blast_Score=166, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI32564151, Length=429, Percent_Identity=31.002331002331, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=490, Percent_Identity=27.7551020408163, Blast_Score=152, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=463, Percent_Identity=27.8617710583153, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=416, Percent_Identity=26.6826923076923, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17551164, Length=494, Percent_Identity=25.1012145748988, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25143876, Length=416, Percent_Identity=26.6826923076923, Blast_Score=130, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=440, Percent_Identity=26.5909090909091, Blast_Score=125, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71986308, Length=425, Percent_Identity=26.3529411764706, Blast_Score=125, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17534119, Length=485, Percent_Identity=25.5670103092783, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=397, Percent_Identity=26.7002518891688, Blast_Score=119, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=319, Percent_Identity=29.7805642633229, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17564084, Length=327, Percent_Identity=27.217125382263, Blast_Score=89, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25146391, Length=329, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=329, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25146394, Length=329, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320917, Length=447, Percent_Identity=30.6487695749441, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6321826, Length=545, Percent_Identity=29.1743119266055, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6323821, Length=461, Percent_Identity=30.58568329718, Blast_Score=174, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6323822, Length=459, Percent_Identity=29.6296296296296, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6325196, Length=457, Percent_Identity=29.1028446389497, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=447, Percent_Identity=27.9642058165548, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6319478, Length=463, Percent_Identity=27.645788336933, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=474, Percent_Identity=22.1518987341772, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=324, Percent_Identity=27.4691358024691, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI20129399, Length=466, Percent_Identity=29.1845493562232, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281362580, Length=448, Percent_Identity=29.2410714285714, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472918, Length=448, Percent_Identity=29.2410714285714, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472926, Length=448, Percent_Identity=29.2410714285714, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472936, Length=448, Percent_Identity=29.2410714285714, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21356737, Length=448, Percent_Identity=29.2410714285714, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24668425, Length=482, Percent_Identity=27.1784232365145, Blast_Score=171, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24668417, Length=482, Percent_Identity=27.1784232365145, Blast_Score=171, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24668413, Length=482, Percent_Identity=27.1784232365145, Blast_Score=171, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24585660, Length=479, Percent_Identity=26.5135699373695, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24650465, Length=460, Percent_Identity=27.8260869565217, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28574525, Length=483, Percent_Identity=25.4658385093168, Blast_Score=147, Evalue=4e-35,
Organism=Drosophila melanogaster, GI28571802, Length=472, Percent_Identity=25.8474576271186, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28571800, Length=472, Percent_Identity=25.8474576271186, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI28571806, Length=472, Percent_Identity=25.8474576271186, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28571798, Length=472, Percent_Identity=25.8474576271186, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28571796, Length=472, Percent_Identity=25.8474576271186, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28571794, Length=472, Percent_Identity=25.8474576271186, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24666674, Length=455, Percent_Identity=27.2527472527473, Blast_Score=140, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24638876, Length=429, Percent_Identity=26.5734265734266, Blast_Score=101, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24638878, Length=429, Percent_Identity=26.5734265734266, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360299, Length=332, Percent_Identity=28.6144578313253, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281360297, Length=332, Percent_Identity=28.6144578313253, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281360295, Length=332, Percent_Identity=28.6144578313253, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24586250, Length=332, Percent_Identity=28.6144578313253, Blast_Score=88, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45552499, Length=332, Percent_Identity=28.0120481927711, Blast_Score=88, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281360301, Length=332, Percent_Identity=28.6144578313253, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281360303, Length=332, Percent_Identity=28.0120481927711, Blast_Score=87, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 128165; Mature: 128165

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFESFAHQQSALRDAITAAYRRDERECVQALLPQAAMSPEQVASVQDLARRLVTEVRRE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RTRSSGVDALMHEFSLDSSEGIALMCLAEALLRIPDRETADKLIRDKISRGDWKAHLGNS
HHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCC
SSLFVNAAAWGLLVTGKLVSSHSANGLSAAMTRLIAKGGEPLIRKGVDMAMRMLGKQFVT
CCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GETIEEALANGREREARGYRFSYDMLGEAAMTEADAQRYLKDYVTAIHAIGKESNGRGIY
HHHHHHHHHCCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DGPGISVKLSAIHPRYARLKHERMMTELLPRLKALFLLAKQYNIGLNIDAEEADRLEISM
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
DLVEALANDADLNGFEGIGIVVQAYQKRCPFVIDFLIDLARRTGHRFMVRLVKGAYWDAE
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IKRAQVDGLPGYPVYTRKVYTDVSYLACAKKLLAAQDAIYPQFATHNAYSLSAIYNLAAG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHCC
KDYEFQCLHGMGETLYDQVVGKDKLGKACRIYAPVGSHETLLAYLVRRLLENGANSSFVN
CCCCCHHHHHCCHHHHHHHHCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHH
RIVDENVSIDELVTDPVAEAAGFSGMPHSKIPLPEALYGEGRRNSKGLDLSSEHVLATLQ
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHH
LGLQASEQQRWAAFPMLGDGDVTDGELQEVRNPADHSDVVGKVIEASAADVERALALSAG
HCCCCCCCHHHEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAAAWAATPVAERAASIRRMADLMEAHMPALMGLAVREAGKTLNNAIAEVREAVDFCRYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQIVSEFDNASHRPLGPVVCISPWNFPLAIFIGEVVASLAAGNTVLAKPAEQTSLIAAY
HHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
AVRLLHEAGIPRAALQFLPGRGEVVGAALTGDARIQGVIFTGSTEVAQIINRTLAKRQDD
HHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCEEEEEEEECCHHHHHHHHHHHHHCCCC
PVLVAETGGMNAMIVDSSALPEQVVTDVLSSAFDSAGQRCSALRVLYLQNDIADKVIAMI
CEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGAMDELTIGNPAKLTTDVGPVIDAEAQAGLLAHIARMKNSARAMHQTKLSAACEQGTFV
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
APTLFEIDNLSELKREVFGPVLHVLRYAASDLDKVVAEINATGYGLTHGIHSRIDETIAD
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ICGKIKVGNIYVNRNIVGAVVGVQPFGGEGKSGTGPKAGGPYYLYRLTRAAWQPKLAAVP
HHCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCC
AAADLSALDALAAAAKAQSLALDGAIAAARKESPLTHSVALPGPTGENNLLSFAGRGRIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEE
CVADDAQALAEQLAAAFAAGNRAVLADNELGRKFASALNGHVSLAADVLEADVDAVLYAG
EECCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
AKAEEARRELAARDGALVPLILRGENGYNVHRLVVERALSVNTTAAGGNASLMSMTE
CCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQFESFAHQQSALRDAITAAYRRDERECVQALLPQAAMSPEQVASVQDLARRLVTEVRRE
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RTRSSGVDALMHEFSLDSSEGIALMCLAEALLRIPDRETADKLIRDKISRGDWKAHLGNS
HHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEECCCC
SSLFVNAAAWGLLVTGKLVSSHSANGLSAAMTRLIAKGGEPLIRKGVDMAMRMLGKQFVT
CCEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GETIEEALANGREREARGYRFSYDMLGEAAMTEADAQRYLKDYVTAIHAIGKESNGRGIY
HHHHHHHHHCCCCHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DGPGISVKLSAIHPRYARLKHERMMTELLPRLKALFLLAKQYNIGLNIDAEEADRLEISM
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
DLVEALANDADLNGFEGIGIVVQAYQKRCPFVIDFLIDLARRTGHRFMVRLVKGAYWDAE
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IKRAQVDGLPGYPVYTRKVYTDVSYLACAKKLLAAQDAIYPQFATHNAYSLSAIYNLAAG
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHHCC
KDYEFQCLHGMGETLYDQVVGKDKLGKACRIYAPVGSHETLLAYLVRRLLENGANSSFVN
CCCCCHHHHHCCHHHHHHHHCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHH
RIVDENVSIDELVTDPVAEAAGFSGMPHSKIPLPEALYGEGRRNSKGLDLSSEHVLATLQ
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHH
LGLQASEQQRWAAFPMLGDGDVTDGELQEVRNPADHSDVVGKVIEASAADVERALALSAG
HCCCCCCCHHHEECCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAAAWAATPVAERAASIRRMADLMEAHMPALMGLAVREAGKTLNNAIAEVREAVDFCRYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAQIVSEFDNASHRPLGPVVCISPWNFPLAIFIGEVVASLAAGNTVLAKPAEQTSLIAAY
HHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHH
AVRLLHEAGIPRAALQFLPGRGEVVGAALTGDARIQGVIFTGSTEVAQIINRTLAKRQDD
HHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCEEEEEEEECCHHHHHHHHHHHHHCCCC
PVLVAETGGMNAMIVDSSALPEQVVTDVLSSAFDSAGQRCSALRVLYLQNDIADKVIAMI
CEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGAMDELTIGNPAKLTTDVGPVIDAEAQAGLLAHIARMKNSARAMHQTKLSAACEQGTFV
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
APTLFEIDNLSELKREVFGPVLHVLRYAASDLDKVVAEINATGYGLTHGIHSRIDETIAD
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ICGKIKVGNIYVNRNIVGAVVGVQPFGGEGKSGTGPKAGGPYYLYRLTRAAWQPKLAAVP
HHCCEEEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCC
AAADLSALDALAAAAKAQSLALDGAIAAARKESPLTHSVALPGPTGENNLLSFAGRGRIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCCCEE
CVADDAQALAEQLAAAFAAGNRAVLADNELGRKFASALNGHVSLAADVLEADVDAVLYAG
EECCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
AKAEEARRELAARDGALVPLILRGENGYNVHRLVVERALSVNTTAAGGNASLMSMTE
CCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]