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The map label for this gene is tpm [H]

Identifier: 34496812

GI number: 34496812

Start: 1428444

End: 1429085

Strand: Direct

Name: tpm [H]

Synonym: CV_1357

Alternate gene names: 34496812

Gene position: 1428444-1429085 (Clockwise)

Preceding gene: 34496811

Following gene: 34496813

Centisome position: 30.07

GC content: 65.89

Gene sequence:

>642_bases
ATGGCGGACAGTTCCAGGGCGGATTTCTGGGAGCAGCGTTACCGCGAGGGCGTGACGCCGTGGGAGGGCGGACAGTTGCC
GCCGCGCGCGCGCGCGTTTTTCGCCGCGCAACGGCCATTGCGGGTATTGATGCCAGGCTGCGGCAGCGCGGCCGACCTGC
CGCCGCTGCTGGCGATGGGGCATGATGTGCTGGCGGTGGACTTCAGCGAAGCGGCGATAGAACTGGCGGCCAGACAGTGG
CCGGAAGCGGCCGGCCGGCTGTTGCTGGCCGATTTTTTCCAATTGCAGATGCCCGCGTTCGATTGCCTGTTCGAGCGGGC
CTTCCTGTGCGCCTTGCCTGTTGGGATGCGATCGCAATATGCTGAACGCGTGGCTGCGCTGATTGCCCCCGGCGGCGCGC
TGGCCGGGGTGTTTTTCGTGGCGGACACCGAGCGGGGGCCGCCGTTCGGGATGCAGGCCGAGGCTTTGCGCGAGCTGCTG
TCGCCATGGTTCGAGCTGGAGGAGGATCTGGCGCTGGACGAGAGCGTGGCGGTCTTCCGCAATCGCGAGCGCTGGATGGT
CTGGCGGCGGCGAGGGTTTGATTTGGGTCAAGTTTCCGAGCATGAATCGACTGGAAATTGCGGCGCGCATCGGAAAGAAT
AA

Upstream 100 bases:

>100_bases
GCGATGCCGCGTCGGCGCGCGAAAACGCATGCGATTGCGCCGGCCTGTCGCTGGAAGCGGCGGCGGCCTGGCTGCGGGGA
CAGTGAAACGAGGGGATGAT

Downstream 100 bases:

>100_bases
CGTCCTAATAAAAAATAGCGGCGGAACAGCCGGCAAGAGGAGAGCAAATGGAGTGGTTCTGGCGGTTGTACACGGTCTCG
GAAAAGACTTTCTGGAACAC

Product: hypothetical protein

Products: NA

Alternate protein names: Thiopurine methyltransferase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MADSSRADFWEQRYREGVTPWEGGQLPPRARAFFAAQRPLRVLMPGCGSAADLPPLLAMGHDVLAVDFSEAAIELAARQW
PEAAGRLLLADFFQLQMPAFDCLFERAFLCALPVGMRSQYAERVAALIAPGGALAGVFFVADTERGPPFGMQAEALRELL
SPWFELEEDLALDESVAVFRNRERWMVWRRRGFDLGQVSEHESTGNCGAHRKE

Sequences:

>Translated_213_residues
MADSSRADFWEQRYREGVTPWEGGQLPPRARAFFAAQRPLRVLMPGCGSAADLPPLLAMGHDVLAVDFSEAAIELAARQW
PEAAGRLLLADFFQLQMPAFDCLFERAFLCALPVGMRSQYAERVAALIAPGGALAGVFFVADTERGPPFGMQAEALRELL
SPWFELEEDLALDESVAVFRNRERWMVWRRRGFDLGQVSEHESTGNCGAHRKE
>Mature_212_residues
ADSSRADFWEQRYREGVTPWEGGQLPPRARAFFAAQRPLRVLMPGCGSAADLPPLLAMGHDVLAVDFSEAAIELAARQWP
EAAGRLLLADFFQLQMPAFDCLFERAFLCALPVGMRSQYAERVAALIAPGGALAGVFFVADTERGPPFGMQAEALRELLS
PWFELEEDLALDESVAVFRNRERWMVWRRRGFDLGQVSEHESTGNCGAHRKE

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TPMT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022474
- InterPro:   IPR008854
- InterPro:   IPR016822 [H]

Pfam domain/function: PF05724 TPMT [H]

EC number: =2.1.1.67 [H]

Molecular weight: Translated: 23743; Mature: 23612

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSSRADFWEQRYREGVTPWEGGQLPPRARAFFAAQRPLRVLMPGCGSAADLPPLLAMG
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHEECCCCCCCCCCCHHHHCC
HDVLAVDFSEAAIELAARQWPEAAGRLLLADFFQLQMPAFDCLFERAFLCALPVGMRSQY
CCEEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHH
AERVAALIAPGGALAGVFFVADTERGPPFGMQAEALRELLSPWFELEEDLALDESVAVFR
HHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NRERWMVWRRRGFDLGQVSEHESTGNCGAHRKE
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADSSRADFWEQRYREGVTPWEGGQLPPRARAFFAAQRPLRVLMPGCGSAADLPPLLAMG
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHEECCCCCCCCCCCHHHHCC
HDVLAVDFSEAAIELAARQWPEAAGRLLLADFFQLQMPAFDCLFERAFLCALPVGMRSQY
CCEEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHH
AERVAALIAPGGALAGVFFVADTERGPPFGMQAEALRELLSPWFELEEDLALDESVAVFR
HHHHHHHHCCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NRERWMVWRRRGFDLGQVSEHESTGNCGAHRKE
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA