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The map label for this gene is ttdR [H]

Identifier: 34496756

GI number: 34496756

Start: 1370966

End: 1371883

Strand: Direct

Name: ttdR [H]

Synonym: CV_1301

Alternate gene names: 34496756

Gene position: 1370966-1371883 (Clockwise)

Preceding gene: 34496752

Following gene: 34496757

Centisome position: 28.86

GC content: 64.81

Gene sequence:

>918_bases
ATGTTCGACTGGAACGATGTCCGTTTTTTCCTGGCGCTGCAGCGCAATGGCAAGCTGCTGGGCGCGGCGCGCCAGATGGG
CACCACCCACGCCACGGTGGCGCGCCACATCGCCGCGCTGGAAAAGGTGCTGGGCCAGCCCTTGTTCGTTCAGCAGGCGG
ACGGTTACTCCCTCACCGCGGCCGGCCGCCAGCTGCTGCCGCTGGCCGAATCGCTGGAAAACACCGCCTCGCAGATGCTG
GACAGTGGCAGCAAGGGGCATGCCGAGGTTAGCGGCGTGGTGAGGCTGGGCGCGCCGGAAGGGCTGGGCGCGCTGTTTCT
GGCCCGCCACATGCCGGCCTTGATGGCGCGCTATCCGGAACTGGAGATCGACCTGGTGGCGGTGCCGCGCTTCGTCAGCG
TCACCAGCCGCGAGGTGGACATCGCCATCGCGCTGGAGCGGCCGCAAGCCAATATGGTGGTGACGCGCAAGCTGACTGAT
TACTGTCTGGGCCTGTACGCGACTCAGGCCTACCTGGCCGCGCATCCGCCGATACGCGAGCGCGAGGATCTGAACGGCCA
TGCCATCCTCGCCTATGTCGACGACCTGCTGTTCACCCGCGAACTGATGTACCACCATGGCTTGTGTCGCCACCCCAGCA
TGCCCTTGCGCAGCACCAGCGTGGTGGCGCAGCGGGAGGCGGCGCTGGCCGATGGCGGCATCGCAGTGCTGCCTTATTAC
ACGACTTACGATGATCCGCGGCTGACGCAGATCCTGCCGGAGTTGCGCATCATCCGTTCCTACTGGATCAGCGCGCGCAG
CAATATCCGCCGCACGCTGCGCTACCGCGTGGTGTGGGATTACGTGGTGGAGCTGTGCCAGAACATGCAGTGGCTGTTGT
TGCAAGAAGAGCAAAATCGATCAATCGAAACCGCCTAG

Upstream 100 bases:

>100_bases
TAGCCAGCGGAAAACAACCTATGTTAATTTTTTAACAATGGACGGCAAGTTAACTGCTTTTTTCGTGTGCAAATGCACAA
GAACTGTCGCGGAGTAAACC

Downstream 100 bases:

>100_bases
GCTATCCCCATGAGACACGCATATCGGCAATTCGGCCCCGGCACCTTGTACACGGTCCGCTTGCTGCGCGCGCTGGACTA
CCTGTGGCGCCATTTGGACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MFDWNDVRFFLALQRNGKLLGAARQMGTTHATVARHIAALEKVLGQPLFVQQADGYSLTAAGRQLLPLAESLENTASQML
DSGSKGHAEVSGVVRLGAPEGLGALFLARHMPALMARYPELEIDLVAVPRFVSVTSREVDIAIALERPQANMVVTRKLTD
YCLGLYATQAYLAAHPPIREREDLNGHAILAYVDDLLFTRELMYHHGLCRHPSMPLRSTSVVAQREAALADGGIAVLPYY
TTYDDPRLTQILPELRIIRSYWISARSNIRRTLRYRVVWDYVVELCQNMQWLLLQEEQNRSIETA

Sequences:

>Translated_305_residues
MFDWNDVRFFLALQRNGKLLGAARQMGTTHATVARHIAALEKVLGQPLFVQQADGYSLTAAGRQLLPLAESLENTASQML
DSGSKGHAEVSGVVRLGAPEGLGALFLARHMPALMARYPELEIDLVAVPRFVSVTSREVDIAIALERPQANMVVTRKLTD
YCLGLYATQAYLAAHPPIREREDLNGHAILAYVDDLLFTRELMYHHGLCRHPSMPLRSTSVVAQREAALADGGIAVLPYY
TTYDDPRLTQILPELRIIRSYWISARSNIRRTLRYRVVWDYVVELCQNMQWLLLQEEQNRSIETA
>Mature_305_residues
MFDWNDVRFFLALQRNGKLLGAARQMGTTHATVARHIAALEKVLGQPLFVQQADGYSLTAAGRQLLPLAESLENTASQML
DSGSKGHAEVSGVVRLGAPEGLGALFLARHMPALMARYPELEIDLVAVPRFVSVTSREVDIAIALERPQANMVVTRKLTD
YCLGLYATQAYLAAHPPIREREDLNGHAILAYVDDLLFTRELMYHHGLCRHPSMPLRSTSVVAQREAALADGGIAVLPYY
TTYDDPRLTQILPELRIIRSYWISARSNIRRTLRYRVVWDYVVELCQNMQWLLLQEEQNRSIETA

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=300, Percent_Identity=24.3333333333333, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081978, Length=284, Percent_Identity=23.5915492957746, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34285; Mature: 34285

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDWNDVRFFLALQRNGKLLGAARQMGTTHATVARHIAALEKVLGQPLFVQQADGYSLTA
CCCCCCEEEEEEEECCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEC
AGRQLLPLAESLENTASQMLDSGSKGHAEVSGVVRLGAPEGLGALFLARHMPALMARYPE
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
LEIDLVAVPRFVSVTSREVDIAIALERPQANMVVTRKLTDYCLGLYATQAYLAAHPPIRE
CEEEEEECCHHHHCCCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCC
REDLNGHAILAYVDDLLFTRELMYHHGLCRHPSMPLRSTSVVAQREAALADGGIAVLPYY
CCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEE
TTYDDPRLTQILPELRIIRSYWISARSNIRRTLRYRVVWDYVVELCQNMQWLLLQEEQNR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
SIETA
CCCCC
>Mature Secondary Structure
MFDWNDVRFFLALQRNGKLLGAARQMGTTHATVARHIAALEKVLGQPLFVQQADGYSLTA
CCCCCCEEEEEEEECCCCEEHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEC
AGRQLLPLAESLENTASQMLDSGSKGHAEVSGVVRLGAPEGLGALFLARHMPALMARYPE
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
LEIDLVAVPRFVSVTSREVDIAIALERPQANMVVTRKLTDYCLGLYATQAYLAAHPPIRE
CEEEEEECCHHHHCCCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCC
REDLNGHAILAYVDDLLFTRELMYHHGLCRHPSMPLRSTSVVAQREAALADGGIAVLPYY
CCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEE
TTYDDPRLTQILPELRIIRSYWISARSNIRRTLRYRVVWDYVVELCQNMQWLLLQEEQNR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
SIETA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]