Click here to switch to the map view.

The map label for this gene is corA [H]

Identifier: 34496718

GI number: 34496718

Start: 1327397

End: 1328434

Strand: Direct

Name: corA [H]

Synonym: CV_1263

Alternate gene names: 34496718

Gene position: 1327397-1328434 (Clockwise)

Preceding gene: 34496717

Following gene: 34496720

Centisome position: 27.94

GC content: 66.09

Gene sequence:

>1038_bases
CTGCCGACGCTGGGGGAGCAGGCGGGAACGCTGCTGTCGGTGGGCGATGCCAAGCACGCCGGCACCGCGCTGTCGCTGTT
CGACTTCGGGCCGGAGGACATGGCGGAGGTGGCCGACTTCCCGATCGCCGACCTGGCCGCCTACCGCCTGCGCGGCGAGG
TGATGTGGCTCAATGTCTACGGCCTGAGCGACGCCGCCGCCATCCAGGCGATAGGCGAACGCTTCGGCCTGCACCCGCTG
GTGCAGGAGGACATCCTCAACGCCCGCCAGCGGCCCAAGCTGGAAGATTACGACGACTACCTGTTCCTGGCCTGCCGCGT
GTTCGATTACCAGCAGGGCGCGCGGCTGCAGTCCGACCAGATGTACCTGGTGCTGGGCGACGGCTTCGTGCTCACCTTCC
AGGAAAAGCCCACCGGCGTGTTCGAGCAGGTGCGGGAGCGGCTGCGCAAGGGGCGCGGCGCGTTGCGGCGGCGCGGCGCC
GACTACCTGGCCTATTCGCTGCTGGACGCCATCATCGACGACTACTTCGGCGTGCTCGGCCAGTTCAACGACAAGGTGGA
GCGCGCAGACGGCCAGTTGCTGGCCGGCCGCGACAACGGCGTGCTGCGGCAAATCCAGCGGCTGAAGCGCGATTGCCTGA
AGCTCAGGCGGGCGCTGCTGCCGCTGCGCGAGGCGCTGCTGTCGCTGAACCGTGGAGATGACGAGCGCTTTGGCGACGAT
ACCCGCGTTTACCTGCGCGACGCTTACGACCACGTGGTCCACGTGCTGGAGTCGCTGGAGATGAACCGCGAGATGGTCGG
CGACATGATGGACCTCTACCTGTCCACCCAATCGCACCGGCTCAACCTGCAGATGCGGGTGCTGACCGTGATCACGATGA
TCTTCATGCCGCTGACGCTGATCGCCGGCATCTACGGCATGAATTTCGAGAACATGCCGGAGCTGAAGTGGCACTACGGC
TACTACATCGTGCTGCTGGCGATGGGCGGCATTTCCGCCGGCATGGGTTGGTGGTTCTGGAAGCGGCGCTGGATCTGA

Upstream 100 bases:

>100_bases
AGCTTCCGCCAGGAAGTGAACCAGTGGAAGAATGTCGGCTTCCAGCTCGACATCGTGCAGAAATAGGCTGCCGATGCGCC
ATCCGGAATTGAAGGAAAGG

Downstream 100 bases:

>100_bases
TCCCGCGGCCGGGACGGGAAAACGGGGAGAGCGATTCTCCCCGTTTTTATTTCGGCTTCACACCTCGTCGGATCGCAGCC
GCTTGACGCCGGCCTGGCGC

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MPTLGEQAGTLLSVGDAKHAGTALSLFDFGPEDMAEVADFPIADLAAYRLRGEVMWLNVYGLSDAAAIQAIGERFGLHPL
VQEDILNARQRPKLEDYDDYLFLACRVFDYQQGARLQSDQMYLVLGDGFVLTFQEKPTGVFEQVRERLRKGRGALRRRGA
DYLAYSLLDAIIDDYFGVLGQFNDKVERADGQLLAGRDNGVLRQIQRLKRDCLKLRRALLPLREALLSLNRGDDERFGDD
TRVYLRDAYDHVVHVLESLEMNREMVGDMMDLYLSTQSHRLNLQMRVLTVITMIFMPLTLIAGIYGMNFENMPELKWHYG
YYIVLLAMGGISAGMGWWFWKRRWI

Sequences:

>Translated_345_residues
MPTLGEQAGTLLSVGDAKHAGTALSLFDFGPEDMAEVADFPIADLAAYRLRGEVMWLNVYGLSDAAAIQAIGERFGLHPL
VQEDILNARQRPKLEDYDDYLFLACRVFDYQQGARLQSDQMYLVLGDGFVLTFQEKPTGVFEQVRERLRKGRGALRRRGA
DYLAYSLLDAIIDDYFGVLGQFNDKVERADGQLLAGRDNGVLRQIQRLKRDCLKLRRALLPLREALLSLNRGDDERFGDD
TRVYLRDAYDHVVHVLESLEMNREMVGDMMDLYLSTQSHRLNLQMRVLTVITMIFMPLTLIAGIYGMNFENMPELKWHYG
YYIVLLAMGGISAGMGWWFWKRRWI
>Mature_344_residues
PTLGEQAGTLLSVGDAKHAGTALSLFDFGPEDMAEVADFPIADLAAYRLRGEVMWLNVYGLSDAAAIQAIGERFGLHPLV
QEDILNARQRPKLEDYDDYLFLACRVFDYQQGARLQSDQMYLVLGDGFVLTFQEKPTGVFEQVRERLRKGRGALRRRGAD
YLAYSLLDAIIDDYFGVLGQFNDKVERADGQLLAGRDNGVLRQIQRLKRDCLKLRRALLPLREALLSLNRGDDERFGDDT
RVYLRDAYDHVVHVLESLEMNREMVGDMMDLYLSTQSHRLNLQMRVLTVITMIFMPLTLIAGIYGMNFENMPELKWHYGY
YIVLLAMGGISAGMGWWFWKRRWI

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=283, Percent_Identity=25.0883392226148, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787604, Length=274, Percent_Identity=19.7080291970803, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321058, Length=352, Percent_Identity=24.7159090909091, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324442, Length=342, Percent_Identity=22.5146198830409, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 39524; Mature: 39393

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLGEQAGTLLSVGDAKHAGTALSLFDFGPEDMAEVADFPIADLAAYRLRGEVMWLNVY
CCCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
GLSDAAAIQAIGERFGLHPLVQEDILNARQRPKLEDYDDYLFLACRVFDYQQGARLQSDQ
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
MYLVLGDGFVLTFQEKPTGVFEQVRERLRKGRGALRRRGADYLAYSLLDAIIDDYFGVLG
EEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
QFNDKVERADGQLLAGRDNGVLRQIQRLKRDCLKLRRALLPLREALLSLNRGDDERFGDD
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TRVYLRDAYDHVVHVLESLEMNREMVGDMMDLYLSTQSHRLNLQMRVLTVITMIFMPLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHH
IAGIYGMNFENMPELKWHYGYYIVLLAMGGISAGMGWWFWKRRWI
HHHHHCCCCCCCCCCCHHHHHHEEEEECCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
PTLGEQAGTLLSVGDAKHAGTALSLFDFGPEDMAEVADFPIADLAAYRLRGEVMWLNVY
CCCCCCCCCEEEECCCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
GLSDAAAIQAIGERFGLHPLVQEDILNARQRPKLEDYDDYLFLACRVFDYQQGARLQSDQ
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
MYLVLGDGFVLTFQEKPTGVFEQVRERLRKGRGALRRRGADYLAYSLLDAIIDDYFGVLG
EEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
QFNDKVERADGQLLAGRDNGVLRQIQRLKRDCLKLRRALLPLREALLSLNRGDDERFGDD
HHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TRVYLRDAYDHVVHVLESLEMNREMVGDMMDLYLSTQSHRLNLQMRVLTVITMIFMPLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHH
IAGIYGMNFENMPELKWHYGYYIVLLAMGGISAGMGWWFWKRRWI
HHHHHCCCCCCCCCCCHHHHHHEEEEECCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]