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The map label for this gene is rtcR [H]

Identifier: 34496491

GI number: 34496491

Start: 1084835

End: 1086442

Strand: Reverse

Name: rtcR [H]

Synonym: CV_1036

Alternate gene names: 34496491

Gene position: 1086442-1084835 (Counterclockwise)

Preceding gene: 34496498

Following gene: 34496490

Centisome position: 22.87

GC content: 63.06

Gene sequence:

>1608_bases
ATGAAAAACAAGGTCGCAATAGGATTCCTGGGCACGGTGCTGGACAAGGGGGGCTACGGCCAGGCACGCTGGCAAAAATG
GCGCCCCAGCATCGGCATCTGCCGGCAGCCGCAGTTGCCGCTAGCGCGGCTGGAATTGCTGCACGACAACCATCACCATC
AGTTGGCAGAACTGACCGCACGCGACATCGCCGAGATATCTCCGGAAACCGAGGTGAGGCTGCATGCAGTCAATCTGGAA
GATCCATGGGATTTCGGCGAGGTGTATTCGGCGCTGGACGACTTCGCAGCCGGCTACGCCTTCGACACCGAGCAGGAGGA
CTACCTGCTTCACATCACAACCGGCACCCACGTCGCGCAGATCTGCTGGTTCCTGCTGGCCGAGTCTCGCCGCATTCCGG
CCCGATTGCTGCAAAGCTCGCCGACGCGGCAGGCCAACGACTTCGCCGGCCGAGTCAGCGTGATCGATCTCGATCTCGCC
CGATACGACCACATCGCCAGCCGTTTCGCGCAGCAGAGCGAAGACACGGTGGCCTTTCTCAAGTCCGGCATCGCCACGCT
CAATCCGGGCTTCAACCGGATGATAGAGCAGATCGAACGAGTGGCTACGCGCTCATCGGCCCCCATCCTGCTGCGCGGCC
CGACTGGCGCGGGCAAAAGTCAGCTGGCCCGGCGGCTGTATGAATTGAAAAAGGCGCGTCGCCAATTGTCCGGCCGTTTC
GTTGAAGTCAACTGTGCCACCCTGCGCGGGGACAGCGCGATGTCCGCGCTGTTCGGCCACGTCAAGGGCGCGTTCACAGG
CGCGCTGAACGAACGCGCAGGCTTGCTGCGCAGCGCCGACGGCGGGCTGCTGTTTCTGGACGAGGTCGGCGAACTGGGCT
TGGACGAACAGGCCATGCTGTTAAAGGCCATAGAGGAGAAACGCTTTCTCCCCTTTGGCGGCGACCGCGAAGCCAGCAGC
GATTTCCAGCTGGTATGCGGCACCATGCGCAATCTGCGGCAGTGGGTGCGCGAGGGAAAGTTCCGCGAGGATCTTTATGC
CCGCATCAATCTATGGCACTTTGAGTTGCCCGGCCTAGCCGCCCGCCGCGAAGACATAGAGCCCAATCTGGAATTCGAAC
TGGCCAGACACGCCGGCGAACAAGGCCGGCACGTGCGCTTCAACGCCGAAGCCCGCCGCGCTTACCTGGATTTCGCGCTG
TCGCAGGATGCCCTATGGCTAGGCAATTTCCGCGAGCTGTCGGCTTCGGTCACGCGTATGGCCACGCTGGCGGATGCCGG
ACGCATCGACAACGGCCTGGTGAACGAAGAGATTGGCCGCCTACGGGAGGACTGGGGCGGGGAGCGGCAAACCGACGCTC
CCCCTTGCCCGCTGAGTAGCGAGCAATGGGAAGGCCTGGACCTGTTCGACCGCGCGCAGCTGGAAACGGTGCTTCGCGTC
TGCCGCCAATCGGCCAGCTTATCCGATGCTGGTCGTCGCTTATTCGCCGTTTCACGCCAAGGCAAAACCCATCCCAACGA
CGCCGACCGGCTGCGCAAATATCTGGCGCGCTTCGGCCTCAGCTGGCAAACCTTGCGCAAGGAGGGCACCCTGCCTGACG
GAGGCTGA

Upstream 100 bases:

>100_bases
ACAAAAAAAATCAACACCAATCAATCACTCAAACTCACGCCCGGCACCACCCTGAAAAAAGCGATAAAATCATCTATTAA
ATTATCCAATTAGATAAGAA

Downstream 100 bases:

>100_bases
CACCGTACATGTCGTTACGGTTGTGAACAGATACAAATCGCAATCAGTAGCTATCTTTCCTTTGCGCTTGCGAAACAAAA
CGGGGCCATAGTGCAAGCAT

Product: transcriptional regulatory protein rtcr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 535

Protein sequence:

>535_residues
MKNKVAIGFLGTVLDKGGYGQARWQKWRPSIGICRQPQLPLARLELLHDNHHHQLAELTARDIAEISPETEVRLHAVNLE
DPWDFGEVYSALDDFAAGYAFDTEQEDYLLHITTGTHVAQICWFLLAESRRIPARLLQSSPTRQANDFAGRVSVIDLDLA
RYDHIASRFAQQSEDTVAFLKSGIATLNPGFNRMIEQIERVATRSSAPILLRGPTGAGKSQLARRLYELKKARRQLSGRF
VEVNCATLRGDSAMSALFGHVKGAFTGALNERAGLLRSADGGLLFLDEVGELGLDEQAMLLKAIEEKRFLPFGGDREASS
DFQLVCGTMRNLRQWVREGKFREDLYARINLWHFELPGLAARREDIEPNLEFELARHAGEQGRHVRFNAEARRAYLDFAL
SQDALWLGNFRELSASVTRMATLADAGRIDNGLVNEEIGRLREDWGGERQTDAPPCPLSSEQWEGLDLFDRAQLETVLRV
CRQSASLSDAGRRLFAVSRQGKTHPNDADRLRKYLARFGLSWQTLRKEGTLPDGG

Sequences:

>Translated_535_residues
MKNKVAIGFLGTVLDKGGYGQARWQKWRPSIGICRQPQLPLARLELLHDNHHHQLAELTARDIAEISPETEVRLHAVNLE
DPWDFGEVYSALDDFAAGYAFDTEQEDYLLHITTGTHVAQICWFLLAESRRIPARLLQSSPTRQANDFAGRVSVIDLDLA
RYDHIASRFAQQSEDTVAFLKSGIATLNPGFNRMIEQIERVATRSSAPILLRGPTGAGKSQLARRLYELKKARRQLSGRF
VEVNCATLRGDSAMSALFGHVKGAFTGALNERAGLLRSADGGLLFLDEVGELGLDEQAMLLKAIEEKRFLPFGGDREASS
DFQLVCGTMRNLRQWVREGKFREDLYARINLWHFELPGLAARREDIEPNLEFELARHAGEQGRHVRFNAEARRAYLDFAL
SQDALWLGNFRELSASVTRMATLADAGRIDNGLVNEEIGRLREDWGGERQTDAPPCPLSSEQWEGLDLFDRAQLETVLRV
CRQSASLSDAGRRLFAVSRQGKTHPNDADRLRKYLARFGLSWQTLRKEGTLPDGG
>Mature_535_residues
MKNKVAIGFLGTVLDKGGYGQARWQKWRPSIGICRQPQLPLARLELLHDNHHHQLAELTARDIAEISPETEVRLHAVNLE
DPWDFGEVYSALDDFAAGYAFDTEQEDYLLHITTGTHVAQICWFLLAESRRIPARLLQSSPTRQANDFAGRVSVIDLDLA
RYDHIASRFAQQSEDTVAFLKSGIATLNPGFNRMIEQIERVATRSSAPILLRGPTGAGKSQLARRLYELKKARRQLSGRF
VEVNCATLRGDSAMSALFGHVKGAFTGALNERAGLLRSADGGLLFLDEVGELGLDEQAMLLKAIEEKRFLPFGGDREASS
DFQLVCGTMRNLRQWVREGKFREDLYARINLWHFELPGLAARREDIEPNLEFELARHAGEQGRHVRFNAEARRAYLDFAL
SQDALWLGNFRELSASVTRMATLADAGRIDNGLVNEEIGRLREDWGGERQTDAPPCPLSSEQWEGLDLFDRAQLETVLRV
CRQSASLSDAGRRLFAVSRQGKTHPNDADRLRKYLARFGLSWQTLRKEGTLPDGG

Specific function: Transcriptional repressor of the rtcAB genes. Interacts with sigma-54 [H]

COG id: COG4650

COG function: function code KT; Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789828, Length=530, Percent_Identity=65.8490566037736, Blast_Score=692, Evalue=0.0,
Organism=Escherichia coli, GI1788905, Length=297, Percent_Identity=33.6700336700337, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1788550, Length=251, Percent_Identity=37.8486055776892, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789233, Length=249, Percent_Identity=35.3413654618474, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI87082117, Length=261, Percent_Identity=35.2490421455939, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790437, Length=242, Percent_Identity=38.0165289256198, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1790299, Length=315, Percent_Identity=33.6507936507937, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI87082152, Length=265, Percent_Identity=36.2264150943396, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1787583, Length=344, Percent_Identity=31.6860465116279, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789087, Length=234, Percent_Identity=35.4700854700855, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786524, Length=237, Percent_Identity=36.2869198312236, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87081872, Length=236, Percent_Identity=34.7457627118644, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI87081858, Length=242, Percent_Identity=27.6859504132231, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078
- InterPro:   IPR009715
- InterPro:   IPR017183 [H]

Pfam domain/function: PF06956 RtcR; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 60093; Mature: 60093

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKVAIGFLGTVLDKGGYGQARWQKWRPSIGICRQPQLPLARLELLHDNHHHQLAELTA
CCCCEEEEHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHH
RDIAEISPETEVRLHAVNLEDPWDFGEVYSALDDFAAGYAFDTEQEDYLLHITTGTHVAQ
HHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
ICWFLLAESRRIPARLLQSSPTRQANDFAGRVSVIDLDLARYDHIASRFAQQSEDTVAFL
HHHHHHHCCCCCHHHHHCCCCCCCCHHHCCEEEEEEEHHHHHHHHHHHHHHCCCHHHHHH
KSGIATLNPGFNRMIEQIERVATRSSAPILLRGPTGAGKSQLARRLYELKKARRQLSGRF
HHCCHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCE
VEVNCATLRGDSAMSALFGHVKGAFTGALNERAGLLRSADGGLLFLDEVGELGLDEQAML
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHH
LKAIEEKRFLPFGGDREASSDFQLVCGTMRNLRQWVREGKFREDLYARINLWHFELPGLA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEEECCCCH
ARREDIEPNLEFELARHAGEQGRHVRFNAEARRAYLDFALSQDALWLGNFRELSASVTRM
HHHHCCCCCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHH
ATLADAGRIDNGLVNEEIGRLREDWGGERQTDAPPCPLSSEQWEGLDLFDRAQLETVLRV
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CRQSASLSDAGRRLFAVSRQGKTHPNDADRLRKYLARFGLSWQTLRKEGTLPDGG
HHHCCCHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MKNKVAIGFLGTVLDKGGYGQARWQKWRPSIGICRQPQLPLARLELLHDNHHHQLAELTA
CCCCEEEEHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHH
RDIAEISPETEVRLHAVNLEDPWDFGEVYSALDDFAAGYAFDTEQEDYLLHITTGTHVAQ
HHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
ICWFLLAESRRIPARLLQSSPTRQANDFAGRVSVIDLDLARYDHIASRFAQQSEDTVAFL
HHHHHHHCCCCCHHHHHCCCCCCCCHHHCCEEEEEEEHHHHHHHHHHHHHHCCCHHHHHH
KSGIATLNPGFNRMIEQIERVATRSSAPILLRGPTGAGKSQLARRLYELKKARRQLSGRF
HHCCHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCE
VEVNCATLRGDSAMSALFGHVKGAFTGALNERAGLLRSADGGLLFLDEVGELGLDEQAML
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHH
LKAIEEKRFLPFGGDREASSDFQLVCGTMRNLRQWVREGKFREDLYARINLWHFELPGLA
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEEEEECCCCH
ARREDIEPNLEFELARHAGEQGRHVRFNAEARRAYLDFALSQDALWLGNFRELSASVTRM
HHHHCCCCCCHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHH
ATLADAGRIDNGLVNEEIGRLREDWGGERQTDAPPCPLSSEQWEGLDLFDRAQLETVLRV
HHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
CRQSASLSDAGRRLFAVSRQGKTHPNDADRLRKYLARFGLSWQTLRKEGTLPDGG
HHHCCCHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3045764; 7984428; 7920643; 9738023 [H]