Click here to switch to the map view.

The map label for this gene is tcp [H]

Identifier: 34496466

GI number: 34496466

Start: 1049369

End: 1050988

Strand: Reverse

Name: tcp [H]

Synonym: CV_1011

Alternate gene names: 34496466

Gene position: 1050988-1049369 (Counterclockwise)

Preceding gene: 34496467

Following gene: 34496465

Centisome position: 22.12

GC content: 67.72

Gene sequence:

>1620_bases
ATGAAAACATTCACCGTCCGCCGGCAATTCGTCCTGCTGGCCGCCTGCGCGCTGCTGGGACTGGGAGGACTGACCCTCAC
CGCCTGGCAGGGCCTGCGCACCGTGATGATCAACGGCGCGATGTACCACCAGATGGTGATCGGCAAGGACTTCATCAACG
ACCTGGATCCCCCTACCCAGCAGCTGATCTCCAGCTTCCTGCTGGTCAACCAGCTGCGCAACACCAACGATGCGTCGATG
CGCCAGCAACTGGCGAACCAGCTGCAGAAACAGCGCGCCGTGTTCTACGACGGCCAGCGGAAATGGGGCAACAGCGAGTT
GCCCCAGGCGATGCGCGACATGCTGACGCAGAAAGTGAAGCCGCCGGCGGACGCCTTCTTCCAGGAAATCGACAGCCACT
ACCTGCCGGCGCTGGAGGCCCACGACCAGCTGGCGATCAACCAATCGTTCGACCGCCTGTCCGCGCAATACGATCTCAAC
GATCAGGCGATGCAACCCCTGATCGCCAAGACCATGGAGATGCAGAAGCAGATGGAAGGCGAGGCGCAGCGCATCACTTC
GCAGACCTTCGCCGCCGTGGCCGCGGTCAGCGCCTTGGTGCTGCTGCTGCTGGTCGGCTCGCTGGTCCTGATCTACCGCC
AGTTGATCCGCGGCCTGGGCGGAGAACCCCACGAGGTGGCCCGGATCACCGGCGAAGTGGCCGCCGGCCGGCTGGACGTC
GAGATGCCGCCCGCGCCGCCGGGCAGCCTGTCCGACTCGGTGCAGCAGATGTGCCGGCAGCTGCTGGCCATCATCGCCGA
GGTGAAGAACAGCTCGGACGGCATCGCCTGCGCCGCGCAGCAGATCAGTTCCACCGCGATGGCGCTGTCGCAGGGCGCCA
GCACCTCGGCCGCCGGCCTGCAGCAAAGCTCGGCCTCGATCGAGCAGGTATCGGCGTCCATCACCCAGACCAGCGACAAC
TCCCGCACCACCGAAGCCATCGCGGAGAAGGCCTCCGACGAGGCCACCCAGGGCGGCGAGGCGGTGCAGCAGACGGTGAC
GGCGATGCGGCAGATCGCCGAGAAGATAAGCATCATCGACGACATCGCCTATCAGACCAATCTGCTGGCGCTGAACGCCG
CCATCGAGGCCGCCCGCGCCGGCAAGCACGGCGCCGGCTTCGCCGTGGTGGCGGCCGAGGTCCGCAAGCTGGCCGAGCGC
AGCCAGGTGGCGGCCCAGGAGATCGGCGAGCTGGCGGAGCGCAGCGTCACCGTCTCCGAGCAGGCCGGCCGGCTGCTGAA
GGAAATCGTGCGCTCCAGCGGCCGCACCGCCGACCTGGTACAGGAAATCGCCGCCGCCACCCGGGAACAGGCCGGCGGCA
TCGGCCAGATCAGCCACGCGGTCCAGCACCTGAACCACTCGACCCAGCAGAATGCCGCCGCCAGTGAGGAATTGGCGTCC
ACCGCCGAGGAAATGAGCCACCAGGCAGAAAGGCTGCAGCAGGCGATGGCCTTTTTCAGGCTGGGCGCGGAAGCCGCGCG
CGCATCGCCCCCGCCCGCGCCGCCCAAACCCGTGGCGCCCGGCGGGGCCATCCGGGCCGCGTCCGAGCCGGACGAACTGG
AGGACATGTTCCGCTTCTGA

Upstream 100 bases:

>100_bases
GTGCTGTCGGTCGGCGAAATGTCGCTGCTGTCCGGACTGAGCCGCCAGGAAGAGGCGCAGGAAGAATGACGCCGCCCAAC
CGTCCGAAACGGAAACCGAG

Downstream 100 bases:

>100_bases
CAACGCGCTGTACTAGATTGAAACCATGACGACACCGACGGCCACCAGGCCGCGCACCAGGAAGGCCAGCACCATGCCGC
ATACTCCGCCGGCGTACCCG

Product: methyl-accepting chemotaxis protein II

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKTFTVRRQFVLLAACALLGLGGLTLTAWQGLRTVMINGAMYHQMVIGKDFINDLDPPTQQLISSFLLVNQLRNTNDASM
RQQLANQLQKQRAVFYDGQRKWGNSELPQAMRDMLTQKVKPPADAFFQEIDSHYLPALEAHDQLAINQSFDRLSAQYDLN
DQAMQPLIAKTMEMQKQMEGEAQRITSQTFAAVAAVSALVLLLLVGSLVLIYRQLIRGLGGEPHEVARITGEVAAGRLDV
EMPPAPPGSLSDSVQQMCRQLLAIIAEVKNSSDGIACAAQQISSTAMALSQGASTSAAGLQQSSASIEQVSASITQTSDN
SRTTEAIAEKASDEATQGGEAVQQTVTAMRQIAEKISIIDDIAYQTNLLALNAAIEAARAGKHGAGFAVVAAEVRKLAER
SQVAAQEIGELAERSVTVSEQAGRLLKEIVRSSGRTADLVQEIAAATREQAGGIGQISHAVQHLNHSTQQNAAASEELAS
TAEEMSHQAERLQQAMAFFRLGAEAARASPPPAPPKPVAPGGAIRAASEPDELEDMFRF

Sequences:

>Translated_539_residues
MKTFTVRRQFVLLAACALLGLGGLTLTAWQGLRTVMINGAMYHQMVIGKDFINDLDPPTQQLISSFLLVNQLRNTNDASM
RQQLANQLQKQRAVFYDGQRKWGNSELPQAMRDMLTQKVKPPADAFFQEIDSHYLPALEAHDQLAINQSFDRLSAQYDLN
DQAMQPLIAKTMEMQKQMEGEAQRITSQTFAAVAAVSALVLLLLVGSLVLIYRQLIRGLGGEPHEVARITGEVAAGRLDV
EMPPAPPGSLSDSVQQMCRQLLAIIAEVKNSSDGIACAAQQISSTAMALSQGASTSAAGLQQSSASIEQVSASITQTSDN
SRTTEAIAEKASDEATQGGEAVQQTVTAMRQIAEKISIIDDIAYQTNLLALNAAIEAARAGKHGAGFAVVAAEVRKLAER
SQVAAQEIGELAERSVTVSEQAGRLLKEIVRSSGRTADLVQEIAAATREQAGGIGQISHAVQHLNHSTQQNAAASEELAS
TAEEMSHQAERLQQAMAFFRLGAEAARASPPPAPPKPVAPGGAIRAASEPDELEDMFRF
>Mature_539_residues
MKTFTVRRQFVLLAACALLGLGGLTLTAWQGLRTVMINGAMYHQMVIGKDFINDLDPPTQQLISSFLLVNQLRNTNDASM
RQQLANQLQKQRAVFYDGQRKWGNSELPQAMRDMLTQKVKPPADAFFQEIDSHYLPALEAHDQLAINQSFDRLSAQYDLN
DQAMQPLIAKTMEMQKQMEGEAQRITSQTFAAVAAVSALVLLLLVGSLVLIYRQLIRGLGGEPHEVARITGEVAAGRLDV
EMPPAPPGSLSDSVQQMCRQLLAIIAEVKNSSDGIACAAQQISSTAMALSQGASTSAAGLQQSSASIEQVSASITQTSDN
SRTTEAIAEKASDEATQGGEAVQQTVTAMRQIAEKISIIDDIAYQTNLLALNAAIEAARAGKHGAGFAVVAAEVRKLAER
SQVAAQEIGELAERSVTVSEQAGRLLKEIVRSSGRTADLVQEIAAATREQAGGIGQISHAVQHLNHSTQQNAAASEELAS
TAEEMSHQAERLQQAMAFFRLGAEAARASPPPAPPKPVAPGGAIRAASEPDELEDMFRF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=321, Percent_Identity=39.5638629283489, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1787690, Length=442, Percent_Identity=33.9366515837104, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI2367378, Length=298, Percent_Identity=41.2751677852349, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788194, Length=385, Percent_Identity=34.025974025974, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1789453, Length=261, Percent_Identity=37.1647509578544, Blast_Score=145, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57805; Mature: 57805

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFTVRRQFVLLAACALLGLGGLTLTAWQGLRTVMINGAMYHQMVIGKDFINDLDPPTQ
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
QLISSFLLVNQLRNTNDASMRQQLANQLQKQRAVFYDGQRKWGNSELPQAMRDMLTQKVK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
PPADAFFQEIDSHYLPALEAHDQLAINQSFDRLSAQYDLNDQAMQPLIAKTMEMQKQMEG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EAQRITSQTFAAVAAVSALVLLLLVGSLVLIYRQLIRGLGGEPHEVARITGEVAAGRLDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEECC
EMPPAPPGSLSDSVQQMCRQLLAIIAEVKNSSDGIACAAQQISSTAMALSQGASTSAAGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
QQSSASIEQVSASITQTSDNSRTTEAIAEKASDEATQGGEAVQQTVTAMRQIAEKISIID
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
DIAYQTNLLALNAAIEAARAGKHGAGFAVVAAEVRKLAERSQVAAQEIGELAERSVTVSE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QAGRLLKEIVRSSGRTADLVQEIAAATREQAGGIGQISHAVQHLNHSTQQNAAASEELAS
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
TAEEMSHQAERLQQAMAFFRLGAEAARASPPPAPPKPVAPGGAIRAASEPDELEDMFRF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]