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The map label for this gene is ptsG [H]

Identifier: 34496434

GI number: 34496434

Start: 1013038

End: 1014804

Strand: Reverse

Name: ptsG [H]

Synonym: CV_0979

Alternate gene names: 34496434

Gene position: 1014804-1013038 (Counterclockwise)

Preceding gene: 34496435

Following gene: 34496431

Centisome position: 21.36

GC content: 67.46

Gene sequence:

>1767_bases
ATGTTTAGTCAATCATTCGCTTTTCTGCAGAAGATCGGCAAGGCGCTGATGCTGCCGGTGGCGGTGCTGCCGGTGGCCGG
CCTGCTGCTCGGCATCGGCGCGACCGACTTCCACACCCAGAACACGGTCTTCCTGGCGATCCTGTCGCTGATGAAGAACT
CCGGCGACGTGATCTTCGGCAACCTGCCGCTGATCTTCGCCGTGGGCGTGGCGCTCGGCTTCACCGAGAACGACGGCGTC
GCCGCCATCGCCGCCGTGATCGGCCATCTGGTCACCACCGTGACCCTGGGCGTGATGGCCGGCATCCTGGGCGTGGCCAC
CACGCCCATCATGGGCCTGCCGTCGATCCAGACCGGCGTGTTCGGCGGCATCCTCGCCGGCGGCCTGGCGGCCTATATGT
TCAACCGCTTCTACCGGATCAAGCTGCCCGAATACCTGGGCTTCTTCGCCGGCAAGCGCTTCGTGCCCATCATCACCGCC
GTCGGCGCCATCGGCCTGGGCGTGGTGCTGTCCTTCGTATGGCCCCCGATCGGCAACGGCATCAAGTCGTTCTCGCAATG
GGCGGCCGTCAGCGACCCCCGCACCGCGGCCACCGTCTACGGCTTCGTCGAGCGGATGCTGATCCCCTTCGGCCTGCACC
ACATCTGGAACGTGCCGTTCTTCTTCGAAATCGGCGCCTTCCCGGACGCGGCCGGCAAGATCATCCACGGCGACATCAAC
CGCTTCTTCGCCGGCGACCCAACCGCGGGCATCCTGTCCGGCGCCTTCCTGTTCAAGATGTTCGGCCTGCCTGCCGCGGC
CATCGCCATCTGGCACTCGGCCAAGCCGGAAAACCGCGTCAAGGTGGGCGGCATCATGATCTCCGCCGCGCTGACCTCCT
TCCTGACCGGCATCACCGAGCCGATCGAGTTCTCCTTCCTGTTCGTGGCGCCGGTGCTGTACCTGATCCACGCCGTGCTG
GCCGCCTCCACCCAGTTCGTGGCCAACACGCTGGACATGCACATGGGCTTCACCTTCTCCCAGGGCGGCATCGACTTCCT
GATGTTCAACCTGATCGGCGACAAGTCCAAGCATGCCGGCTACGTGTTCATCCTGGGCCCGATCTACGCGGCGATCTACT
ACTCGGTGTTCCGTTTCGTGATCGCCAAGTTCAATCTGAAGACCCCGGGCCGCGAGGATGAAAGCGCGGAAACTTCCGGC
GCCGTCAGCGAAGACCAGCGCGCCCGCGCGCTGGTGCTGGCCTTCGGTGGCCGCTCCAACATCCGCAGCCTGGACGCCTG
CATCACCCGTCTGCGCATCGCGGTGCAGGACACCGCCAAGGTCGACCAGGCCAAGCTGAAGTCCATGGGCGCGTCCGGCG
TGGTGGTGGTCGGCAGCGGCATCCAGGCCATCTTCGGACCGCTGTCGGAAAACCTGAAGACCGACATGGAAATCTACCTG
CGCGGCGCCGGCAGTGACGCCGAGCTGCCGTCCGCCCAGGCCGCCGCTCCTGCCGCCTCTCCGGCCCCCGCGGCCGCGGC
TGCGCCGGCCGCCGCCAAGGCTGACGTCGCCGCGCTGAAACAGGCGCTGGGCGGCGCGGCCAACCTCGGCAAGGTGGAAG
CCATCGCCCACACTCGCCTGCGGGTGGAGCTGAAGGATGCCGCCCGCTTCGACGAAGCCGCCGCCCGCGCGGCCGGCGTA
TCCGCCGTCACCCTGGTGGCGCCCGGCGTGCTGCACCTGATCGTCGGCGACCAGGCGGCGGCGCTCGCCGCCTCGCTGCA
AGGCTGA

Upstream 100 bases:

>100_bases
GCGCCGCCCAAGCGGACCTGGCGGGCGATGGGGCTTTATAGAGGGGACGGCGTCACAGCCGCTCGACATTCCATAAGCAT
GTCAAAGCAGGATAATAATC

Downstream 100 bases:

>100_bases
CCGCGCCCGGTCCCGCCGCAAAAAAACGCCAGCGAATCTCGCTGGCGTTTTTTATCGCCCCCTCCCTCAGCGCGCCACCC
TCAGCCCGCCCTCTATGCCC

Product: protein-N p-phosphohistidine-sugar phosphotransferase

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MFSQSFAFLQKIGKALMLPVAVLPVAGLLLGIGATDFHTQNTVFLAILSLMKNSGDVIFGNLPLIFAVGVALGFTENDGV
AAIAAVIGHLVTTVTLGVMAGILGVATTPIMGLPSIQTGVFGGILAGGLAAYMFNRFYRIKLPEYLGFFAGKRFVPIITA
VGAIGLGVVLSFVWPPIGNGIKSFSQWAAVSDPRTAATVYGFVERMLIPFGLHHIWNVPFFFEIGAFPDAAGKIIHGDIN
RFFAGDPTAGILSGAFLFKMFGLPAAAIAIWHSAKPENRVKVGGIMISAALTSFLTGITEPIEFSFLFVAPVLYLIHAVL
AASTQFVANTLDMHMGFTFSQGGIDFLMFNLIGDKSKHAGYVFILGPIYAAIYYSVFRFVIAKFNLKTPGREDESAETSG
AVSEDQRARALVLAFGGRSNIRSLDACITRLRIAVQDTAKVDQAKLKSMGASGVVVVGSGIQAIFGPLSENLKTDMEIYL
RGAGSDAELPSAQAAAPAASPAPAAAAAPAAAKADVAALKQALGGAANLGKVEAIAHTRLRVELKDAARFDEAAARAAGV
SAVTLVAPGVLHLIVGDQAAALAASLQG

Sequences:

>Translated_588_residues
MFSQSFAFLQKIGKALMLPVAVLPVAGLLLGIGATDFHTQNTVFLAILSLMKNSGDVIFGNLPLIFAVGVALGFTENDGV
AAIAAVIGHLVTTVTLGVMAGILGVATTPIMGLPSIQTGVFGGILAGGLAAYMFNRFYRIKLPEYLGFFAGKRFVPIITA
VGAIGLGVVLSFVWPPIGNGIKSFSQWAAVSDPRTAATVYGFVERMLIPFGLHHIWNVPFFFEIGAFPDAAGKIIHGDIN
RFFAGDPTAGILSGAFLFKMFGLPAAAIAIWHSAKPENRVKVGGIMISAALTSFLTGITEPIEFSFLFVAPVLYLIHAVL
AASTQFVANTLDMHMGFTFSQGGIDFLMFNLIGDKSKHAGYVFILGPIYAAIYYSVFRFVIAKFNLKTPGREDESAETSG
AVSEDQRARALVLAFGGRSNIRSLDACITRLRIAVQDTAKVDQAKLKSMGASGVVVVGSGIQAIFGPLSENLKTDMEIYL
RGAGSDAELPSAQAAAPAASPAPAAAAAPAAAKADVAALKQALGGAANLGKVEAIAHTRLRVELKDAARFDEAAARAAGV
SAVTLVAPGVLHLIVGDQAAALAASLQG
>Mature_588_residues
MFSQSFAFLQKIGKALMLPVAVLPVAGLLLGIGATDFHTQNTVFLAILSLMKNSGDVIFGNLPLIFAVGVALGFTENDGV
AAIAAVIGHLVTTVTLGVMAGILGVATTPIMGLPSIQTGVFGGILAGGLAAYMFNRFYRIKLPEYLGFFAGKRFVPIITA
VGAIGLGVVLSFVWPPIGNGIKSFSQWAAVSDPRTAATVYGFVERMLIPFGLHHIWNVPFFFEIGAFPDAAGKIIHGDIN
RFFAGDPTAGILSGAFLFKMFGLPAAAIAIWHSAKPENRVKVGGIMISAALTSFLTGITEPIEFSFLFVAPVLYLIHAVL
AASTQFVANTLDMHMGFTFSQGGIDFLMFNLIGDKSKHAGYVFILGPIYAAIYYSVFRFVIAKFNLKTPGREDESAETSG
AVSEDQRARALVLAFGGRSNIRSLDACITRLRIAVQDTAKVDQAKLKSMGASGVVVVGSGIQAIFGPLSENLKTDMEIYL
RGAGSDAELPSAQAAAPAASPAPAAAAAPAAAKADVAALKQALGGAANLGKVEAIAHTRLRVELKDAARFDEAAARAAGV
SAVTLVAPGVLHLIVGDQAAALAASLQG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=483, Percent_Identity=60.6625258799172, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1786894, Length=481, Percent_Identity=43.4511434511435, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1787908, Length=512, Percent_Identity=36.1328125, Blast_Score=275, Evalue=5e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 61274; Mature: 61274

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEECCHHHHHHHHCCC
>Mature Secondary Structure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EEEEHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]