Click here to switch to the map view.

The map label for this gene is rstA [H]

Identifier: 34496216

GI number: 34496216

Start: 780796

End: 781509

Strand: Reverse

Name: rstA [H]

Synonym: CV_0761

Alternate gene names: 34496216

Gene position: 781509-780796 (Counterclockwise)

Preceding gene: 34496218

Following gene: 34496215

Centisome position: 16.45

GC content: 69.05

Gene sequence:

>714_bases
ATGGCACAACACATTCTGATCGTCGAAGACGACGCCAGGCTGGCCGAGCTGATCGCCGCCTACCTGACCAAGCATGGCTA
CCAGGTCAGCCTGCACGGCCGCGGCGACACCGCGCCTGCCTTCATCCTGGAAACCCGCCCGGACCTGGTGGTGCTGGACG
TGATGCTGCCGGGCAAGGAGGGTTTCGACGTCTGCCGCGACGTGCGCCCGCACTACGGCGGCCGCATCCTGATGATGACC
GCGCGCGACGAGGACGTGGACGAGATCCTGGGCCTGGAGCTGGGCGCCGACGACTACCTGGCCAAACCGGTGGAGCCGCG
CCGGCTGCTAGCCCGCATCCGCGCGCTGCTGCGCCGCAGCGGCGGCGCCCGCCAGGAAGGCGGCGGCGTCGCGGTGGAGA
ACGACGGTATCACCTTCGGCCAGTTCAGTATCAGCCAGGCCACCCGCGAGGCGCTGCTGGGTGACGAGCAGATCGAGCTG
ACCACCGCCGAGTTCGACCTGCTATGGCTGCTGGCCACCCACGCCGGCCAGGTGCTGTCCCGCGACGACATCATGAGCGA
GCTGCGCGGCATCGGCTTCGACGGCCTGGACCGCTCGATCGACGCGCGCATCTCGCGGCTGCGCCGCAAACTGGGCGACA
ACCCCGATGCGCCGGCGCGGATCAAGACCGTGCGCGGCAAGGGCTATTTGTTCTCGCGCAGCGACTGGGAATAG

Upstream 100 bases:

>100_bases
ACCGCTGCTTTGATTCTGTCGGCATAGCAGCCGAAATACAAGCCTGCCAGCCCGAACGGCCCGTGTTACTATTTTTGCTG
GGAAATCGGAATATCTCGCA

Downstream 100 bases:

>100_bases
CCGATGCCGTCCAAGAACCTGCGCGGCTGGCTGCGGCCGTCGCTGGGTACGCTGTTCGCCCGCTACTTCCTGATCACCAT
GCTGATCCAGCTGTTGATCA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MAQHILIVEDDARLAELIAAYLTKHGYQVSLHGRGDTAPAFILETRPDLVVLDVMLPGKEGFDVCRDVRPHYGGRILMMT
ARDEDVDEILGLELGADDYLAKPVEPRRLLARIRALLRRSGGARQEGGGVAVENDGITFGQFSISQATREALLGDEQIEL
TTAEFDLLWLLATHAGQVLSRDDIMSELRGIGFDGLDRSIDARISRLRRKLGDNPDAPARIKTVRGKGYLFSRSDWE

Sequences:

>Translated_237_residues
MAQHILIVEDDARLAELIAAYLTKHGYQVSLHGRGDTAPAFILETRPDLVVLDVMLPGKEGFDVCRDVRPHYGGRILMMT
ARDEDVDEILGLELGADDYLAKPVEPRRLLARIRALLRRSGGARQEGGGVAVENDGITFGQFSISQATREALLGDEQIEL
TTAEFDLLWLLATHAGQVLSRDDIMSELRGIGFDGLDRSIDARISRLRRKLGDNPDAPARIKTVRGKGYLFSRSDWE
>Mature_236_residues
AQHILIVEDDARLAELIAAYLTKHGYQVSLHGRGDTAPAFILETRPDLVVLDVMLPGKEGFDVCRDVRPHYGGRILMMTA
RDEDVDEILGLELGADDYLAKPVEPRRLLARIRALLRRSGGARQEGGGVAVENDGITFGQFSISQATREALLGDEQIELT
TAEFDLLWLLATHAGQVLSRDDIMSELRGIGFDGLDRSIDARISRLRRKLGDNPDAPARIKTVRGKGYLFSRSDWE

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=49.5762711864407, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=44.2982456140351, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=41.5584415584416, Blast_Score=150, Evalue=5e-38,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=38.2222222222222, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=36.4406779661017, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=36.5638766519824, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.0472103004292, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=36.2445414847162, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.0689655172414, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.8017621145374, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.8777292576419, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786911, Length=231, Percent_Identity=30.7359307359307, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790552, Length=228, Percent_Identity=32.8947368421053, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26279; Mature: 26148

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQHILIVEDDARLAELIAAYLTKHGYQVSLHGRGDTAPAFILETRPDLVVLDVMLPGKE
CCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEEEEECCCC
GFDVCRDVRPHYGGRILMMTARDEDVDEILGLELGADDYLAKPVEPRRLLARIRALLRRS
CHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHC
GGARQEGGGVAVENDGITFGQFSISQATREALLGDEQIELTTAEFDLLWLLATHAGQVLS
CCCCCCCCCEEEECCCEEEEEEHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCHHHH
RDDIMSELRGIGFDGLDRSIDARISRLRRKLGDNPDAPARIKTVRGKGYLFSRSDWE
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEECCCCCC
>Mature Secondary Structure 
AQHILIVEDDARLAELIAAYLTKHGYQVSLHGRGDTAPAFILETRPDLVVLDVMLPGKE
CCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEEEEECCCC
GFDVCRDVRPHYGGRILMMTARDEDVDEILGLELGADDYLAKPVEPRRLLARIRALLRRS
CHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHHC
GGARQEGGGVAVENDGITFGQFSISQATREALLGDEQIELTTAEFDLLWLLATHAGQVLS
CCCCCCCCCEEEECCCEEEEEEHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCHHHH
RDDIMSELRGIGFDGLDRSIDARISRLRRKLGDNPDAPARIKTVRGKGYLFSRSDWE
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]