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The map label for this gene is arnC [H]

Identifier: 34496204

GI number: 34496204

Start: 769215

End: 770165

Strand: Reverse

Name: arnC [H]

Synonym: CV_0749

Alternate gene names: 34496204

Gene position: 770165-769215 (Counterclockwise)

Preceding gene: 34496205

Following gene: 34496203

Centisome position: 16.21

GC content: 64.77

Gene sequence:

>951_bases
ATGAATACCGACATCAACCTTTCCGTCGTCATCCCGGTCTACAACGAGCAGGACGTGCTGCAGGCGCTGTTCGACCGCCT
GTATCCGGCGCTGGACGCGCTGAACCTGCGCTACGAGATCGTGTTCATCAACGACGGCAGCCGCGACAAGAGCGCGGCCA
TGCTGGCCGACCAGTTCGCCCAGCGCCCCGACGTCACCCGCGTGGTGCTGTTCAACGGCAACTTCGGCCAGCACCGCGCC
ATCCTGGCCGGTTTCGAGCACAGCCGCGGCGAACGCGTGGTGACGCTGGACGCCGACCTGCAGAACCCGCCGGAAGACAT
CCGGCTGCTGCTGGCGGAAATGGACAAGGGCCACGATTACGTCGGCTCCATCCGACGCCAGCGCAATGACAGCCTGTGGC
GCCACGTCGCCAGCCGGGCGATGAACCGCCTGCGCGAGAAGCTGACCCGGATCAAGATGACCGACCAAGGCTGCATGATG
CGCGCCTACAGCCGCCGCATCATCGACACCATCAACCAGTGCAACGAGCTGCACACCTTCATCCCGGCGCTGGCCTACCA
GTTCTCGCAGCATCCGACCGAGGTCGTCGTCGGCCACGAGGAGCGCTTCGCCGGCGAGTCCAAATACTCGCTGTACAGCC
TGATCCGGCTGAACTTCGACCTGATGACCGGCTTCTCCATCGTGCCGCTGCAATGGTTTTCGCTGATGGGCATGGCGGTG
TCGGCCGGCTCCGGCCTCTTGGTGGTCTACCTGCTGCTGCGCCGGCTGATCCTGGGGCCGGAAGTCGGCGGCGTGTTCAC
GCTGTTCGCCATCGCCTTCTTCCTGATCGGCCTCGCGCTGTTCGGCATCGGCCTGTTGGGCGAATACATCGGCCGCATCT
ACCAGGAAGTCCGCTCGCGCCCGCGCTACGTGATCCAGACGGTGCTGGAGCAAAAGGGAGGCCAGGCATGA

Upstream 100 bases:

>100_bases
CCGTCACCCTGCCGCTGTTCCCCGGCATGCGCGACGAGGACGTGCTCCGCGTCTGCCAAACCTTCAGCGCCGTCCTGCGC
GCCGTTTTACACTGAGATAC

Downstream 100 bases:

>100_bases
GCCGCGCCGTCGTCTTCGCCTACCACAACGTCGGCGTGCGCTGCCTGAAGGCGCTGATCGGCCGCGGCGTCGACGTCGCG
CTGGTCGTCACCCACCAGGA

Product: dolichyl-phosphate b-D-mannosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNTDINLSVVIPVYNEQDVLQALFDRLYPALDALNLRYEIVFINDGSRDKSAAMLADQFAQRPDVTRVVLFNGNFGQHRA
ILAGFEHSRGERVVTLDADLQNPPEDIRLLLAEMDKGHDYVGSIRRQRNDSLWRHVASRAMNRLREKLTRIKMTDQGCMM
RAYSRRIIDTINQCNELHTFIPALAYQFSQHPTEVVVGHEERFAGESKYSLYSLIRLNFDLMTGFSIVPLQWFSLMGMAV
SAGSGLLVVYLLLRRLILGPEVGGVFTLFAIAFFLIGLALFGIGLLGEYIGRIYQEVRSRPRYVIQTVLEQKGGQA

Sequences:

>Translated_316_residues
MNTDINLSVVIPVYNEQDVLQALFDRLYPALDALNLRYEIVFINDGSRDKSAAMLADQFAQRPDVTRVVLFNGNFGQHRA
ILAGFEHSRGERVVTLDADLQNPPEDIRLLLAEMDKGHDYVGSIRRQRNDSLWRHVASRAMNRLREKLTRIKMTDQGCMM
RAYSRRIIDTINQCNELHTFIPALAYQFSQHPTEVVVGHEERFAGESKYSLYSLIRLNFDLMTGFSIVPLQWFSLMGMAV
SAGSGLLVVYLLLRRLILGPEVGGVFTLFAIAFFLIGLALFGIGLLGEYIGRIYQEVRSRPRYVIQTVLEQKGGQA
>Mature_316_residues
MNTDINLSVVIPVYNEQDVLQALFDRLYPALDALNLRYEIVFINDGSRDKSAAMLADQFAQRPDVTRVVLFNGNFGQHRA
ILAGFEHSRGERVVTLDADLQNPPEDIRLLLAEMDKGHDYVGSIRRQRNDSLWRHVASRAMNRLREKLTRIKMTDQGCMM
RAYSRRIIDTINQCNELHTFIPALAYQFSQHPTEVVVGHEERFAGESKYSLYSLIRLNFDLMTGFSIVPLQWFSLMGMAV
SAGSGLLVVYLLLRRLILGPEVGGVFTLFAIAFFLIGLALFGIGLLGEYIGRIYQEVRSRPRYVIQTVLEQKGGQA

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=232, Percent_Identity=26.2931034482759, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788588, Length=306, Percent_Identity=48.3660130718954, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI1788692, Length=305, Percent_Identity=29.8360655737705, Blast_Score=157, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6325441, Length=152, Percent_Identity=26.9736842105263, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585265, Length=231, Percent_Identity=26.4069264069264, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 35877; Mature: 35877

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDINLSVVIPVYNEQDVLQALFDRLYPALDALNLRYEIVFINDGSRDKSAAMLADQFA
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHH
QRPDVTRVVLFNGNFGQHRAILAGFEHSRGERVVTLDADLQNPPEDIRLLLAEMDKGHDY
CCCCCEEEEEEECCCCCCHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHH
VGSIRRQRNDSLWRHVASRAMNRLREKLTRIKMTDQGCMMRAYSRRIIDTINQCNELHTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPALAYQFSQHPTEVVVGHEERFAGESKYSLYSLIRLNFDLMTGFSIVPLQWFSLMGMAV
HHHHHHHHCCCCCEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SAGSGLLVVYLLLRRLILGPEVGGVFTLFAIAFFLIGLALFGIGLLGEYIGRIYQEVRSR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRYVIQTVLEQKGGQA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNTDINLSVVIPVYNEQDVLQALFDRLYPALDALNLRYEIVFINDGSRDKSAAMLADQFA
CCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHHHHHHH
QRPDVTRVVLFNGNFGQHRAILAGFEHSRGERVVTLDADLQNPPEDIRLLLAEMDKGHDY
CCCCCEEEEEEECCCCCCHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCHH
VGSIRRQRNDSLWRHVASRAMNRLREKLTRIKMTDQGCMMRAYSRRIIDTINQCNELHTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPALAYQFSQHPTEVVVGHEERFAGESKYSLYSLIRLNFDLMTGFSIVPLQWFSLMGMAV
HHHHHHHHCCCCCEEEECCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SAGSGLLVVYLLLRRLILGPEVGGVFTLFAIAFFLIGLALFGIGLLGEYIGRIYQEVRSR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PRYVIQTVLEQKGGQA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA