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The map label for this gene is arnA [H]

Identifier: 34496203

GI number: 34496203

Start: 768301

End: 769218

Strand: Reverse

Name: arnA [H]

Synonym: CV_0748

Alternate gene names: 34496203

Gene position: 769218-768301 (Counterclockwise)

Preceding gene: 34496204

Following gene: 34496202

Centisome position: 16.19

GC content: 70.81

Gene sequence:

>918_bases
ATGAGCCGCGCCGTCGTCTTCGCCTACCACAACGTCGGCGTGCGCTGCCTGAAGGCGCTGATCGGCCGCGGCGTCGACGT
CGCGCTGGTCGTCACCCACCAGGACAACCCGAACGAAAACATCTGGTTCCACAGCGTGGCCCAGACGGCGCGCGACTACG
GCATCCCCGTCATCACGCCGGACGATCCCAACTCGCCGGAAGTGGTGGCGCAAGTCCAGGCCTGCCAAGCGGACTTCCTG
TTTTCGTTCTACTACCGCCACATGCTGAAGGCCCCGCTCTTGGAGGCGGCCAAGCGCGGCGCGTACAATATGCACGGCTC
GCTGCTGCCGAAGTACCGCGGCCGGGTGCCGATCAACTGGGCGATCATCCACGGCGAAACCGAAACCGGCGCCACGCTGC
ACCAGATGAACGTCAAGCCGGACAACGGCCCCGTCGTCGACCAGATGGCGGTGCCCATCCTGCCGGACGACACCGCGGAC
GAGGTGTTCGCCAAGGTGACGGTGGCCGCCGAGATGGTGCTGTGGCGCAGCCTGCCCGGCCTGATCGCCGGCGACGCGCC
GCATGTCCAGCAGGACCTGGGCCAGGGCGGCTACTTCGGCGGCCGCAAGCCGGAAGACGGCCGCATCGACGCGCAGGCCC
CGGCCCGGCGACTGCATGATTTCGTCCGCGCGCTGGCCCGCCCCTTCCCCGGCGCCTACGCCGACACCGCGGCCGGCCGC
CTGCTGCTGTGGAAGACGCTGCCGGCCGGCCAGGCCGCGCCGGCCGATCGCGCAGAATTGCGCAGCGCCGATGGCCGGCT
GTGGCTGCATTGCGCCGACGGCGGCCGCCTGGCGGTGCTGGAGGCGGAACTGGACGGGCAGCCGCTGGCCGCCGACAACT
TCGCCGCCCGCGTCGGAAGCGACGCGCTGGCGCTGTGA

Upstream 100 bases:

>100_bases
TCGGCCTGTTGGGCGAATACATCGGCCGCATCTACCAGGAAGTCCGCTCGCGCCCGCGCTACGTGATCCAGACGGTGCTG
GAGCAAAAGGGAGGCCAGGC

Downstream 100 bases:

>100_bases
ACCGATTACCGAATTCGATTTTCCGCCTGCGGGCGAGTGAGGACTTGGAATGAAAAAAGTACTGATCCTGGGCGTGAACG
GCTTCATCGGCCACCACCTG

Product: formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSRAVVFAYHNVGVRCLKALIGRGVDVALVVTHQDNPNENIWFHSVAQTARDYGIPVITPDDPNSPEVVAQVQACQADFL
FSFYYRHMLKAPLLEAAKRGAYNMHGSLLPKYRGRVPINWAIIHGETETGATLHQMNVKPDNGPVVDQMAVPILPDDTAD
EVFAKVTVAAEMVLWRSLPGLIAGDAPHVQQDLGQGGYFGGRKPEDGRIDAQAPARRLHDFVRALARPFPGAYADTAAGR
LLLWKTLPAGQAAPADRAELRSADGRLWLHCADGGRLAVLEAELDGQPLAADNFAARVGSDALAL

Sequences:

>Translated_305_residues
MSRAVVFAYHNVGVRCLKALIGRGVDVALVVTHQDNPNENIWFHSVAQTARDYGIPVITPDDPNSPEVVAQVQACQADFL
FSFYYRHMLKAPLLEAAKRGAYNMHGSLLPKYRGRVPINWAIIHGETETGATLHQMNVKPDNGPVVDQMAVPILPDDTAD
EVFAKVTVAAEMVLWRSLPGLIAGDAPHVQQDLGQGGYFGGRKPEDGRIDAQAPARRLHDFVRALARPFPGAYADTAAGR
LLLWKTLPAGQAAPADRAELRSADGRLWLHCADGGRLAVLEAELDGQPLAADNFAARVGSDALAL
>Mature_304_residues
SRAVVFAYHNVGVRCLKALIGRGVDVALVVTHQDNPNENIWFHSVAQTARDYGIPVITPDDPNSPEVVAQVQACQADFLF
SFYYRHMLKAPLLEAAKRGAYNMHGSLLPKYRGRVPINWAIIHGETETGATLHQMNVKPDNGPVVDQMAVPILPDDTADE
VFAKVTVAAEMVLWRSLPGLIAGDAPHVQQDLGQGGYFGGRKPEDGRIDAQAPARRLHDFVRALARPFPGAYADTAAGRL
LLWKTLPAGQAAPADRAELRSADGRLWLHCADGGRLAVLEAELDGQPLAADNFAARVGSDALAL

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=252, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI238814322, Length=213, Percent_Identity=27.6995305164319, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1788589, Length=297, Percent_Identity=38.047138047138, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789683, Length=248, Percent_Identity=30.241935483871, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI133930964, Length=237, Percent_Identity=27.4261603375527, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582400, Length=146, Percent_Identity=34.2465753424658, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 32978; Mature: 32847

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAVVFAYHNVGVRCLKALIGRGVDVALVVTHQDNPNENIWFHSVAQTARDYGIPVITP
CCCEEEEEECCHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEHHHHHHHHHCCCEEECC
DDPNSPEVVAQVQACQADFLFSFYYRHMLKAPLLEAAKRGAYNMHGSLLPKYRGRVPINW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEE
AIIHGETETGATLHQMNVKPDNGPVVDQMAVPILPDDTADEVFAKVTVAAEMVLWRSLPG
EEEECCCCCCCEEEEEECCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LIAGDAPHVQQDLGQGGYFGGRKPEDGRIDAQAPARRLHDFVRALARPFPGAYADTAAGR
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCCE
LLLWKTLPAGQAAPADRAELRSADGRLWLHCADGGRLAVLEAELDGQPLAADNFAARVGS
EEEEEECCCCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHCCC
DALAL
HHHCC
>Mature Secondary Structure 
SRAVVFAYHNVGVRCLKALIGRGVDVALVVTHQDNPNENIWFHSVAQTARDYGIPVITP
CCEEEEEECCHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEHHHHHHHHHCCCEEECC
DDPNSPEVVAQVQACQADFLFSFYYRHMLKAPLLEAAKRGAYNMHGSLLPKYRGRVPINW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEE
AIIHGETETGATLHQMNVKPDNGPVVDQMAVPILPDDTADEVFAKVTVAAEMVLWRSLPG
EEEECCCCCCCEEEEEECCCCCCCCHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LIAGDAPHVQQDLGQGGYFGGRKPEDGRIDAQAPARRLHDFVRALARPFPGAYADTAAGR
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCCE
LLLWKTLPAGQAAPADRAELRSADGRLWLHCADGGRLAVLEAELDGQPLAADNFAARVGS
EEEEEECCCCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHCCC
DALAL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA