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The map label for this gene is kup2

Identifier: 34496028

GI number: 34496028

Start: 611709

End: 613574

Strand: Reverse

Name: kup2

Synonym: CV_0573

Alternate gene names: 34496028

Gene position: 613574-611709 (Counterclockwise)

Preceding gene: 34496032

Following gene: 34496025

Centisome position: 12.91

GC content: 65.38

Gene sequence:

>1866_bases
ATGCAGGATCACAACAAAAAGGCGATGGCGGGCCTGACCCTGGCCGCTCTCGGCGTGGTCTACGGCGATATCGGCACCAG
CCCGCTGTACACCTTGCGCGAGTGTTTCGTCAGCCAGAACCTCCCCACCACGCCCGACAACATCTTCGGCATTCTGTCGC
TGATCTTCTGGTCGCTGATCTTCGTGGTATCGGTGAAGTACGTGGCTTTCGTGCTGCGCGCCGACAACCGCGGCGAAGGC
GGCATCATGGCGCTGATGGCGCTGGCACGGCATTACACCACCCACGCGGCGCGCTGGAAGATCGTGCTGCTCGGCCTGTT
CGGCGCCGCGCTGTTCTACGGCGACGCCATCATCACCCCGGCGGTGTCGGTGCTGTCCGCCGCCGAAGGCATGGAAGTCG
TCTCCTCCGGCATGGAAGCCTACGTGCTGCCGATGGCGGTCGGCGTGCTGGTGGGGCTGTTCCTGCTGCAGCGCCACGGC
ACCGCCAGGGTCGGCCTGATGTTCGGTCCGGTGATGATGGTCTGGTTCGCCATCCTCGGCATCCTCGGCCTGCACCAGAT
CATCCAGCAGCCAGCGGTGCTGCAGGCGCTGAATCCCTGGCACGCGGTCACCTTCCTCAGCCAGCACGGTTTCCACGCTT
TCCTGACGCTGGGCTCGGTGGTGCTGGCGCTGACCGGCGCCGAGGCGCTGTACGCCGACATGGGCCACTTCGGCAAGACG
CCGATCCGCCGCGCCTGGTTCAGCCTGGTGCTGCCGGGCCTGGGGCTGAACTACTTCGGCCAGGGCGCGCTGCTGATGAG
CAATCCGGCCGCGATCAAGAACCCCTTCTTCCTGCTGGCCCCGGACTGGGCGCTGCTGCCGATGATCGCGCTGGCGACCC
TGGCCACGGTGATCGCGTCGCAGGCGGTGATCTCGGGCGCCTACTCGCTGACCCGCCAGGCCATCCTGCTCGGCTATTGC
CCGCGCCTGGAGGTGCACCACACTTCGGACAAGGAAATCGGCCAGATCTACATGCCCTTCATCAACTGGGCGCTGCTGGT
CGCCGTGCTGGTGGTGGTGCTCACCTTCAAGAATTCATCCAGCCTGGCCGCGGCCTACGGCATCGCCGTCACCGGCACCA
TGTTGATCACCACCATGCTGTTCTTCGTGGTGGCCCGGGTCAACTGGCGCTGGCCGCTGCCGCTGGCGCTGGGCATCACC
CTGCTGTTCGGCGTGATCGACACCGCCTTCTTCGCCGCCAACGTCCACAAGGTGGCGGATGGCGGCTGGCTGCCGCTGGT
GATGGGCATGGCCATCTTCACGTTGATGAGCACCTGGAAACAGGGCCGCGACATCCTGTTCAAGCGCCTGCGCGAACAAG
CGCTGCCGCTGGACGATTTCATCCACAACCTCGAAGCCTACCCGCCCGCCCGGGTGGAGGGCACCGCGGTGTTCCTGACC
AGCACGCTGCACGGCGTGCCGCACGCGCTGCTGCACAACCTGAAGCACAACAAGGTGCTGCACGAGCGGGTGGTGCTGAT
GACGGTGCGCACCGAGGACATTCCCTACGTGCCGGAGGACGAGCGGCTGGAGATCGTGCAGATGTCGGCGTCGTTCTGGC
GCGTGATGGCGCGCTACGGCTTCAAGGAAGAGCCGAACGTGGTCGAGGTGCTGGACAAGTGCGCGAAGGAAGGCTTCGAA
ATGGAGCTGATGGACACCTCGTTCTTCCTGTCGCGGGAGACCATCGTCTCCACCGGCCATCCCGGCATGGCGCGCTGGCG
CCAGAAGATTTTCCTGTGGATGAGCAAGAACGCGCTGCGCGCGACCGACTTCTTCCAGGTGCCGACCAACCGCGTGGTGG
AATTGGGCGCCCAGGTCGAACTGTAA

Upstream 100 bases:

>100_bases
TGCCCGCGTCATCGACAATGAGAGGGCATCCAGCCATGAACAATCCGGACCTCCGTCGCTGCGCGTTCCCTGCAGCGATG
TCCAACCGTAATGGAAGCTT

Downstream 100 bases:

>100_bases
GCGCCGGCTCTGCGGCCAAAAGCAAAAGCGCGCCAAACGGCGCGCTTTTTTTCGCACTCCCCGAACTCAGCGCACCGAAG
GCTGCCGCAGCCGTATCTGC

Product: potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MQDHNKKAMAGLTLAALGVVYGDIGTSPLYTLRECFVSQNLPTTPDNIFGILSLIFWSLIFVVSVKYVAFVLRADNRGEG
GIMALMALARHYTTHAARWKIVLLGLFGAALFYGDAIITPAVSVLSAAEGMEVVSSGMEAYVLPMAVGVLVGLFLLQRHG
TARVGLMFGPVMMVWFAILGILGLHQIIQQPAVLQALNPWHAVTFLSQHGFHAFLTLGSVVLALTGAEALYADMGHFGKT
PIRRAWFSLVLPGLGLNYFGQGALLMSNPAAIKNPFFLLAPDWALLPMIALATLATVIASQAVISGAYSLTRQAILLGYC
PRLEVHHTSDKEIGQIYMPFINWALLVAVLVVVLTFKNSSSLAAAYGIAVTGTMLITTMLFFVVARVNWRWPLPLALGIT
LLFGVIDTAFFAANVHKVADGGWLPLVMGMAIFTLMSTWKQGRDILFKRLREQALPLDDFIHNLEAYPPARVEGTAVFLT
STLHGVPHALLHNLKHNKVLHERVVLMTVRTEDIPYVPEDERLEIVQMSASFWRVMARYGFKEEPNVVEVLDKCAKEGFE
MELMDTSFFLSRETIVSTGHPGMARWRQKIFLWMSKNALRATDFFQVPTNRVVELGAQVEL

Sequences:

>Translated_621_residues
MQDHNKKAMAGLTLAALGVVYGDIGTSPLYTLRECFVSQNLPTTPDNIFGILSLIFWSLIFVVSVKYVAFVLRADNRGEG
GIMALMALARHYTTHAARWKIVLLGLFGAALFYGDAIITPAVSVLSAAEGMEVVSSGMEAYVLPMAVGVLVGLFLLQRHG
TARVGLMFGPVMMVWFAILGILGLHQIIQQPAVLQALNPWHAVTFLSQHGFHAFLTLGSVVLALTGAEALYADMGHFGKT
PIRRAWFSLVLPGLGLNYFGQGALLMSNPAAIKNPFFLLAPDWALLPMIALATLATVIASQAVISGAYSLTRQAILLGYC
PRLEVHHTSDKEIGQIYMPFINWALLVAVLVVVLTFKNSSSLAAAYGIAVTGTMLITTMLFFVVARVNWRWPLPLALGIT
LLFGVIDTAFFAANVHKVADGGWLPLVMGMAIFTLMSTWKQGRDILFKRLREQALPLDDFIHNLEAYPPARVEGTAVFLT
STLHGVPHALLHNLKHNKVLHERVVLMTVRTEDIPYVPEDERLEIVQMSASFWRVMARYGFKEEPNVVEVLDKCAKEGFE
MELMDTSFFLSRETIVSTGHPGMARWRQKIFLWMSKNALRATDFFQVPTNRVVELGAQVEL
>Mature_621_residues
MQDHNKKAMAGLTLAALGVVYGDIGTSPLYTLRECFVSQNLPTTPDNIFGILSLIFWSLIFVVSVKYVAFVLRADNRGEG
GIMALMALARHYTTHAARWKIVLLGLFGAALFYGDAIITPAVSVLSAAEGMEVVSSGMEAYVLPMAVGVLVGLFLLQRHG
TARVGLMFGPVMMVWFAILGILGLHQIIQQPAVLQALNPWHAVTFLSQHGFHAFLTLGSVVLALTGAEALYADMGHFGKT
PIRRAWFSLVLPGLGLNYFGQGALLMSNPAAIKNPFFLLAPDWALLPMIALATLATVIASQAVISGAYSLTRQAILLGYC
PRLEVHHTSDKEIGQIYMPFINWALLVAVLVVVLTFKNSSSLAAAYGIAVTGTMLITTMLFFVVARVNWRWPLPLALGIT
LLFGVIDTAFFAANVHKVADGGWLPLVMGMAIFTLMSTWKQGRDILFKRLREQALPLDDFIHNLEAYPPARVEGTAVFLT
STLHGVPHALLHNLKHNKVLHERVVLMTVRTEDIPYVPEDERLEIVQMSASFWRVMARYGFKEEPNVVEVLDKCAKEGFE
MELMDTSFFLSRETIVSTGHPGMARWRQKIFLWMSKNALRATDFFQVPTNRVVELGAQVEL

Specific function: Transport of potassium into the cell

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family

Homologues:

Organism=Escherichia coli, GI48994960, Length=622, Percent_Identity=55.1446945337621, Blast_Score=710, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KUP2_CHRVO (Q7P0J4)

Other databases:

- EMBL:   AE016825
- RefSeq:   NP_900243.1
- GeneID:   2547272
- GenomeReviews:   AE016825_GR
- KEGG:   cvi:CV_0573
- NMPDR:   fig|243365.1.peg.573
- HOGENOM:   HBG351154
- OMA:   GFTENIN
- PhylomeDB:   Q7P0J4
- ProtClustDB:   CLSK2485295
- BioCyc:   CVIO243365:CV_0573-MONOMER
- HAMAP:   MF_01522
- InterPro:   IPR003855
- InterPro:   IPR023051
- TIGRFAMs:   TIGR00794

Pfam domain/function: PF02705 K_trans

EC number: NA

Molecular weight: Translated: 68472; Mature: 68472

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb2a2418)-; HASH(0xdbea340)-; HASH(0xd94898c)-; HASH(0xd52e530)-; HASH(0xc133854)-; HASH(0xd3af0c0)-; HASH(0xd9167d8)-; HASH(0xb6b90b4)-; HASH(0xadd3ec8)-; HASH(0xd79f518)-; HASH(0xc98af68)-; HASH(0xc2c6624)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHCCCCHHHHHCCCCCCH
>Mature Secondary Structure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CCHHHCCCCHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500782