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The map label for this gene is pabC [H]

Identifier: 33864488

GI number: 33864488

Start: 2351382

End: 2352242

Strand: Direct

Name: pabC [H]

Synonym: PMT2224

Alternate gene names: 33864488

Gene position: 2351382-2352242 (Clockwise)

Preceding gene: 33864487

Following gene: 33864497

Centisome position: 97.53

GC content: 53.31

Gene sequence:

>861_bases
ATGAAAAACCAGATTGCCTGGATCGATGGCAGCTGGGGTAGCACTGCGGAGCTCGCTCTTCCTCTAGGAGATCGAGGCCT
GCAGCTTGCCGATGGCATCTTTGAGACAATTCTGATCCTTGATGGACATCCACAACTCCTCAATGCTCATCTCAGCCGCT
GGCAGACCAGCGCATGCCTACTAGAGATGGCCCCCCCGCCTACAGCGAAATGGTTGACACCTCTGATCAAAGAGGGCCTG
AAACAATGCAACTTGGACAATGGCAATGGGGCCCTGCGCCTCAACTGGAGCCGTGGCGATAGGTCAAGCCGAGGCATCAG
CCTGCCCCAGAGCAACCCGAGTTCAACAACCCATCGCTTCTGGCTAGAGCTGAATGCAGTGGAGCCCTGCTTTACTCCAC
TTACCACGATCATCAGTTGCCATGAGCGTCGCAACGCCAATAGTCGCTTGAGTCGTTGCAAAACCTTCGCCTACGGTCAA
GCGATACAGGCCCGCCACGAAGCACAAAAAGCGAATTGCGATGAGGCCATCCTGCTAAGCACAAGCGGTGAACTTTGTTG
TGGCAGTACCGCCAACCTCATCGTGCGACGAAACAATCATTGGCTCACACCTCGGCTTGCTAGTGGCTGTCTACCAGGTG
TCATGCGACAACAGGGCCTCGAACAAGGATGGCTGCAAGAAACTCAACTAGAAGCCACACCAGAAAAAGATGATCAATGG
CTACTGATTAATAGCCTCAGCTGCCAACCCATCGTGAAGCTCGATGATCATCTGCTCAGAGCATGGTCGGATCCTGAAGG
CCTTTGGTACTCCCTCTTAAAAGCCAACAACACTGACACTTCTCCCAGACATACAGATTAA

Upstream 100 bases:

>100_bases
TACGAGCCCATGCCGGCTGCGGCATCGTGACCGGTTCCGACCCCTATTGCGAAGCTGATGAGCTGAACTGGAAACTGCTG
CCACTACTGGAGGCACTGCA

Downstream 100 bases:

>100_bases
TGCCCCAGCCCTAAACATCTCCATACGCACTCATACACTGAGGAATTGATCCACCACTGCCTGACTAAGATCGCTGGTCG
GACCACTGGCCACAATGCCA

Product: aminotransferase class-IV

Products: NA

Alternate protein names: 4-amino-4-deoxychorismate lyase; ADC lyase; ADCL [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKNQIAWIDGSWGSTAELALPLGDRGLQLADGIFETILILDGHPQLLNAHLSRWQTSACLLEMAPPPTAKWLTPLIKEGL
KQCNLDNGNGALRLNWSRGDRSSRGISLPQSNPSSTTHRFWLELNAVEPCFTPLTTIISCHERRNANSRLSRCKTFAYGQ
AIQARHEAQKANCDEAILLSTSGELCCGSTANLIVRRNNHWLTPRLASGCLPGVMRQQGLEQGWLQETQLEATPEKDDQW
LLINSLSCQPIVKLDDHLLRAWSDPEGLWYSLLKANNTDTSPRHTD

Sequences:

>Translated_286_residues
MKNQIAWIDGSWGSTAELALPLGDRGLQLADGIFETILILDGHPQLLNAHLSRWQTSACLLEMAPPPTAKWLTPLIKEGL
KQCNLDNGNGALRLNWSRGDRSSRGISLPQSNPSSTTHRFWLELNAVEPCFTPLTTIISCHERRNANSRLSRCKTFAYGQ
AIQARHEAQKANCDEAILLSTSGELCCGSTANLIVRRNNHWLTPRLASGCLPGVMRQQGLEQGWLQETQLEATPEKDDQW
LLINSLSCQPIVKLDDHLLRAWSDPEGLWYSLLKANNTDTSPRHTD
>Mature_286_residues
MKNQIAWIDGSWGSTAELALPLGDRGLQLADGIFETILILDGHPQLLNAHLSRWQTSACLLEMAPPPTAKWLTPLIKEGL
KQCNLDNGNGALRLNWSRGDRSSRGISLPQSNPSSTTHRFWLELNAVEPCFTPLTTIISCHERRNANSRLSRCKTFAYGQ
AIQARHEAQKANCDEAILLSTSGELCCGSTANLIVRRNNHWLTPRLASGCLPGVMRQQGLEQGWLQETQLEATPEKDDQW
LLINSLSCQPIVKLDDHLLRAWSDPEGLWYSLLKANNTDTSPRHTD

Specific function: Converts 4-amino-4-deoxychorismate into 4-aminobenzoate (PABA) and pyruvate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=240, Percent_Identity=28.75, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =4.1.3.38 [H]

Molecular weight: Translated: 31865; Mature: 31865

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQIAWIDGSWGSTAELALPLGDRGLQLADGIFETILILDGHPQLLNAHLSRWQTSACL
CCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHEE
LEMAPPPTAKWLTPLIKEGLKQCNLDNGNGALRLNWSRGDRSSRGISLPQSNPSSTTHRF
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEE
WLELNAVEPCFTPLTTIISCHERRNANSRLSRCKTFAYGQAIQARHEAQKANCDEAILLS
EEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
TSGELCCGSTANLIVRRNNHWLTPRLASGCLPGVMRQQGLEQGWLQETQLEATPEKDDQW
CCCCEEECCCCEEEEECCCCEECHHHHHCCCCHHHHHHCCHHCCCCHHCCCCCCCCCCCE
LLINSLSCQPIVKLDDHLLRAWSDPEGLWYSLLKANNTDTSPRHTD
EEEECCCCCEEHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKNQIAWIDGSWGSTAELALPLGDRGLQLADGIFETILILDGHPQLLNAHLSRWQTSACL
CCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHEE
LEMAPPPTAKWLTPLIKEGLKQCNLDNGNGALRLNWSRGDRSSRGISLPQSNPSSTTHRF
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEE
WLELNAVEPCFTPLTTIISCHERRNANSRLSRCKTFAYGQAIQARHEAQKANCDEAILLS
EEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
TSGELCCGSTANLIVRRNNHWLTPRLASGCLPGVMRQQGLEQGWLQETQLEATPEKDDQW
CCCCEEECCCCEEEEECCCCEECHHHHHCCCCHHHHHHCCHHCCCCHHCCCCCCCCCCCE
LLINSLSCQPIVKLDDHLLRAWSDPEGLWYSLLKANNTDTSPRHTD
EEEECCCCCEEHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]