Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 33864472

GI number: 33864472

Start: 2335006

End: 2335410

Strand: Direct

Name: fur [H]

Synonym: PMT2208

Alternate gene names: 33864472

Gene position: 2335006-2335410 (Clockwise)

Preceding gene: 33864468

Following gene: 33864474

Centisome position: 96.85

GC content: 51.85

Gene sequence:

>405_bases
ATGCCTGTCGATCAAAGTCAGCCCACACTGCGGCAGAACCAACTTTTGAAAGAACTACGTTGCTGTTGCGATGAAATGAG
CGGTCAGCAGCTGTATCGCGCCTTGCAGGACAGCCCCTATGCCATGGGACTTGCGACCGTATACAGAAACTTACGCCAGC
TTCAACAACGAGGACTGGTGAGATGCCGACACCTACCTACAGGTGAAACCCTCTATGCGCCAGTGGAAAGGGACCTTCAT
CACCTCACATGCGTGGACTGCGGCAAAACGCTGCCGATCGAGCATTGCCCTTTGCACAACCTCAACATCCCGCAAGAGCA
AAGTCATAATTTTCAGCTGATCTTCCACACACTTGAGTTCTTTGGTCACTGTGAGAGCTGCCAAAAGGATCAAACCCTGA
CCTGA

Upstream 100 bases:

>100_bases
TGCTCGTTGATTCTCTAGAATCATTTATTCAAAAAATTTGTCAAAAGCAATCCTCTTGCCAGCTCCTCTGAGCTAAAAGA
GCAAGTGAACGAGCTCATCC

Downstream 100 bases:

>100_bases
AATCTCACTGAAGAAACGCTTAGGCAGCGGCCCAACCTCCTGCAAAGCTCATACATCAAAGCAATAAAAATGATCAACAA
AAAAAGCTATCACCAGCAAA

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MPVDQSQPTLRQNQLLKELRCCCDEMSGQQLYRALQDSPYAMGLATVYRNLRQLQQRGLVRCRHLPTGETLYAPVERDLH
HLTCVDCGKTLPIEHCPLHNLNIPQEQSHNFQLIFHTLEFFGHCESCQKDQTLT

Sequences:

>Translated_134_residues
MPVDQSQPTLRQNQLLKELRCCCDEMSGQQLYRALQDSPYAMGLATVYRNLRQLQQRGLVRCRHLPTGETLYAPVERDLH
HLTCVDCGKTLPIEHCPLHNLNIPQEQSHNFQLIFHTLEFFGHCESCQKDQTLT
>Mature_133_residues
PVDQSQPTLRQNQLLKELRCCCDEMSGQQLYRALQDSPYAMGLATVYRNLRQLQQRGLVRCRHLPTGETLYAPVERDLHH
LTCVDCGKTLPIEHCPLHNLNIPQEQSHNFQLIFHTLEFFGHCESCQKDQTLT

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=109, Percent_Identity=31.1926605504587, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15532; Mature: 15401

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
6.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVDQSQPTLRQNQLLKELRCCCDEMSGQQLYRALQDSPYAMGLATVYRNLRQLQQRGLV
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RCRHLPTGETLYAPVERDLHHLTCVDCGKTLPIEHCPLHNLNIPQEQSHNFQLIFHTLEF
HHHCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
FGHCESCQKDQTLT
HHHHHHHCCCCCCC
>Mature Secondary Structure 
PVDQSQPTLRQNQLLKELRCCCDEMSGQQLYRALQDSPYAMGLATVYRNLRQLQQRGLV
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RCRHLPTGETLYAPVERDLHHLTCVDCGKTLPIEHCPLHNLNIPQEQSHNFQLIFHTLEF
HHHCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
FGHCESCQKDQTLT
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406286; 11586360; 12142430 [H]