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The map label for this gene is crp1 [C]

Identifier: 33864415

GI number: 33864415

Start: 2269360

End: 2270055

Strand: Reverse

Name: crp1 [C]

Synonym: PMT2151

Alternate gene names: 33864415

Gene position: 2270055-2269360 (Counterclockwise)

Preceding gene: 33864421

Following gene: 33864412

Centisome position: 94.16

GC content: 53.02

Gene sequence:

>696_bases
ATGGCTGTTTTTAGCGTTCAGCAGTTGCAGGCTGTGCAATTTTTTTCGGCTTTAACAACGGATGATTGTGAGCAATTATT
GGATCGCCATCTTGAGTCCAGTCACGGTGCTGACCAGGTTTTCGTGATGGAGCAAGACTGGGGTGAATCGGTTTTTCTGT
TGTGCTCAGGCATGGCCAAAGTTCGCAGTTATACGGCTGATGGCGATGAAGTTGTGATGTCAGTGTTGGGGGAGGGGGAC
CTGTTTGGTGAGATGGCTGTTCTTGATGCCGCACCCAGGTCTGCTGATGTTGTGGCCTTAACGCCAGTGAAACTTTTGAA
GATGAGAGCGTCGCCTTTTGTGACTTTGCTGCGCAAGGAAGTGGGCTTTGCGATTGCCCTTGCTCAGCTTGAGGCATCTC
GCTTGCGGGATCTCAATCAGCGTTTTGCAATCCAGACCAGTGATGCCACGACGCGCTTACTCAATGCATTGGCTTACTTG
GCTCGCAAGAGTTCTTCTGCTGATGATCCCAAAGTGGCGATTCCGCCGTTAGCTCAAAGGGAGTTGGGTCTCATGGCAGG
TTTGTCCAGGGAGACTGCCTCCCGGACATTGAGCAAGCTGCGCAGTCGTGGAACACTGGAGGAGGTCGAAGGCTGCCTGC
GTTTGGTGGATCTGCAGCCGCTCGTTAAACGAGGCCTGTTGCCGCTTGGCGCTTAG

Upstream 100 bases:

>100_bases
TAGTGTGTGAGTGAAGGTTGACTAATGTGCAAATAATTGATTCATATTGAAGAGTGATTTAGGGGTTGCATTATTGTTCA
ATAACTAAAAATAATGAAAC

Downstream 100 bases:

>100_bases
AGCTTTTGAGCACGGTTACGGGTTGAATTGACCAGCCAGAATCGTCTTGGATTTAGGAGTCTTTGGACAGCTTTCAGAAA
AACAAGTTGCTGATCTCGAG

Product: GntR family regulatory protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Catabolite Gene Activator; CAMP-Dependent Transcriptional Regulator; Transcriptional Regulator Crp/Fnr Family Protein; Cyclic AMP Receptor Protein; Catabolite Gene Activator Protein; Regulatory Protein; Transcriptional Regulatory Protein Crp Family; CAMP Receptor Protein; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAVFSVQQLQAVQFFSALTTDDCEQLLDRHLESSHGADQVFVMEQDWGESVFLLCSGMAKVRSYTADGDEVVMSVLGEGD
LFGEMAVLDAAPRSADVVALTPVKLLKMRASPFVTLLRKEVGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYL
ARKSSSADDPKVAIPPLAQRELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGA

Sequences:

>Translated_231_residues
MAVFSVQQLQAVQFFSALTTDDCEQLLDRHLESSHGADQVFVMEQDWGESVFLLCSGMAKVRSYTADGDEVVMSVLGEGD
LFGEMAVLDAAPRSADVVALTPVKLLKMRASPFVTLLRKEVGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYL
ARKSSSADDPKVAIPPLAQRELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGA
>Mature_230_residues
AVFSVQQLQAVQFFSALTTDDCEQLLDRHLESSHGADQVFVMEQDWGESVFLLCSGMAKVRSYTADGDEVVMSVLGEGDL
FGEMAVLDAAPRSADVVALTPVKLLKMRASPFVTLLRKEVGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYLA
RKSSSADDPKVAIPPLAQRELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGA

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25108; Mature: 24977

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFSVQQLQAVQFFSALTTDDCEQLLDRHLESSHGADQVFVMEQDWGESVFLLCSGMAK
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
VRSYTADGDEVVMSVLGEGDLFGEMAVLDAAPRSADVVALTPVKLLKMRASPFVTLLRKE
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHCCHHHHHHHHH
VGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYLARKSSSADDPKVAIPPLAQR
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHH
ELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGA
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVFSVQQLQAVQFFSALTTDDCEQLLDRHLESSHGADQVFVMEQDWGESVFLLCSGMAK
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
VRSYTADGDEVVMSVLGEGDLFGEMAVLDAAPRSADVVALTPVKLLKMRASPFVTLLRKE
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHCCHHHHHHHHH
VGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYLARKSSSADDPKVAIPPLAQR
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHH
ELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGA
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA