Click here to switch to the map view.

The map label for this gene is grxC [C]

Identifier: 33864327

GI number: 33864327

Start: 2171531

End: 2171794

Strand: Reverse

Name: grxC [C]

Synonym: PMT2062

Alternate gene names: 33864327

Gene position: 2171794-2171531 (Counterclockwise)

Preceding gene: 33864334

Following gene: 33864326

Centisome position: 90.08

GC content: 56.44

Gene sequence:

>264_bases
ATGGCCAAGGTTGAGATCTATACCTGGCAGTCATGCCCATTCTGCCTGCGTGCCAAGGCTCTCTTGGATCGCAAAGGGGT
GAGTTACCAGGAGCACGCCATCGATGGCGACCAGGCAGCCCGCGCAGTGATGGCGAGCCGGGCTGGGGGAAAAAACACGT
TGCCCCAGATCTTTATCGATGATCTGAGCATTGGTGGCTGCGATGAGTTGCATGCCCTTGAGGGGGCTCAAAAACTTGAT
GGTTTGCTCCAAGGCAAGGTCTGA

Upstream 100 bases:

>100_bases
AAGTCGGTGAGGTCCAGCAACGTTGGTGCTTGAGTCCAGAGATCTGACGCTATCAGCGGGGCCAGCCTGCATAGGATCTC
AGTGACGTGATCACAGTGCC

Downstream 100 bases:

>100_bases
AGCCATGCGACAGCTGTTCGTCTTGGATCCCCTGCAGTGCATTCAACCTGCCAAGGATTCCTCAGCTGCGTTGATGCAGG
CGGCCCAACGGGCATCAATT

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MAKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQAARAVMASRAGGKNTLPQIFIDDLSIGGCDELHALEGAQKLD
GLLQGKV

Sequences:

>Translated_87_residues
MAKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQAARAVMASRAGGKNTLPQIFIDDLSIGGCDELHALEGAQKLD
GLLQGKV
>Mature_86_residues
AKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQAARAVMASRAGGKNTLPQIFIDDLSIGGCDELHALEGAQKLDG
LLQGKV

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaredoxin family [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=84, Percent_Identity=58.3333333333333, Blast_Score=98, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9404; Mature: 9273

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQAARAVMASRAGGKNTLPQIFID
CCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEC
DLSIGGCDELHALEGAQKLDGLLQGKV
CCCCCCCCHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure 
AKVEIYTWQSCPFCLRAKALLDRKGVSYQEHAIDGDQAARAVMASRAGGKNTLPQIFID
CEEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEC
DLSIGGCDELHALEGAQKLDGLLQGKV
CCCCCCCCHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]