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The map label for this gene is rfbB [C]

Identifier: 33864223

GI number: 33864223

Start: 2069145

End: 2070077

Strand: Direct

Name: rfbB [C]

Synonym: PMT1958

Alternate gene names: 33864223

Gene position: 2069145-2070077 (Clockwise)

Preceding gene: 33864222

Following gene: 33864224

Centisome position: 85.83

GC content: 49.09

Gene sequence:

>933_bases
TTGCAACCGACTCGCAATCTTGTTACCGGAGGCGCTGGTTTTCTTGGTTCGCATTTAGTCGACAGGCTCATGCAGGCGGA
TGAGGAAGTGATTTGCCTCGACAACTATTTCACTGGGCGCAAAGTCAATCTTGCGCAATGGATCGAGCATCCACGCTTCG
AATTAATCAGACATGATGTCACCGAACCAATCAAGCTCGAAGTTGATCGGATCTGGCATCTGGCATGCCCTGCATCACCG
GTTCACTATCAGTTTAATCCGATTAAAACAGCCAAAACCAGTTTTCTTGGTACCTACAACATGCTTGGCCTCGCACGCAG
AGTAGGCGCACGCCTACTACTCGCCAGCACCAGCGAAGTTTACGGCGATCCAGAAATTAATCCCCAGCCAGAAAGTTATC
GCGGCTGCGTTAACACAATCGGGATTCGCAGCTGTTACGACGAGGGAAAGCGAATCGCAGAAACACTCTGCTTCGACTAC
CAGCGCATCCATGCCACGGAGATCAGAGTGATGCGCATCTTCAATACTTATGGCCCCCGAATGTTGCCCGATGACGGCAG
GGTGGTGAGCAACTTCATCATGCAGGCACTACGTGGTGAACCACTAACCCTGTACGGAGATGGCCTACAAACACGTTCAT
TCTGTTATGTGGATGATCTCATTGAAGGCATGTTGCGCCTCATGAACAGTGATACAACTGGACCCATTAACATCGGCAAC
CCCAGTGAATTCACGATTCGCCAACTAGCAGAGTTAGTTCGCAATAGCATCCAACCCAATCTGCCTTTAATCTCAAAGCC
CTTGCCTCAAGACGATCCAATGCAACGCCAGCCAATAATCGACTTAGCAAAAAAAGAACTGGACTGGGAACCATTGATTC
AACTTGAAGATGGACTAACAAGAACGATCGACTGGTTTCGCAAGCAACTATAA

Upstream 100 bases:

>100_bases
TTTCTGCTCCGCATCTCTACAGGTGCGGAGCTTTGTTATTGATATCAAGTGAGCAGACATCTCCGCCTAGACTCAGATCT
AAATATCTAACACTGACGCC

Downstream 100 bases:

>100_bases
AATAATTAAGCAATAGAATTTATCCTGGCCGAGGCAAATTCAAACATTATCCATCAACCAGACAATCCCATTTGCCAAAA
TAAACTATCAAGGATAACAC

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MQPTRNLVTGGAGFLGSHLVDRLMQADEEVICLDNYFTGRKVNLAQWIEHPRFELIRHDVTEPIKLEVDRIWHLACPASP
VHYQFNPIKTAKTSFLGTYNMLGLARRVGARLLLASTSEVYGDPEINPQPESYRGCVNTIGIRSCYDEGKRIAETLCFDY
QRIHATEIRVMRIFNTYGPRMLPDDGRVVSNFIMQALRGEPLTLYGDGLQTRSFCYVDDLIEGMLRLMNSDTTGPINIGN
PSEFTIRQLAELVRNSIQPNLPLISKPLPQDDPMQRQPIIDLAKKELDWEPLIQLEDGLTRTIDWFRKQL

Sequences:

>Translated_310_residues
MQPTRNLVTGGAGFLGSHLVDRLMQADEEVICLDNYFTGRKVNLAQWIEHPRFELIRHDVTEPIKLEVDRIWHLACPASP
VHYQFNPIKTAKTSFLGTYNMLGLARRVGARLLLASTSEVYGDPEINPQPESYRGCVNTIGIRSCYDEGKRIAETLCFDY
QRIHATEIRVMRIFNTYGPRMLPDDGRVVSNFIMQALRGEPLTLYGDGLQTRSFCYVDDLIEGMLRLMNSDTTGPINIGN
PSEFTIRQLAELVRNSIQPNLPLISKPLPQDDPMQRQPIIDLAKKELDWEPLIQLEDGLTRTIDWFRKQL
>Mature_310_residues
MQPTRNLVTGGAGFLGSHLVDRLMQADEEVICLDNYFTGRKVNLAQWIEHPRFELIRHDVTEPIKLEVDRIWHLACPASP
VHYQFNPIKTAKTSFLGTYNMLGLARRVGARLLLASTSEVYGDPEINPQPESYRGCVNTIGIRSCYDEGKRIAETLCFDY
QRIHATEIRVMRIFNTYGPRMLPDDGRVVSNFIMQALRGEPLTLYGDGLQTRSFCYVDDLIEGMLRLMNSDTTGPINIGN
PSEFTIRQLAELVRNSIQPNLPLISKPLPQDDPMQRQPIIDLAKKELDWEPLIQLEDGLTRTIDWFRKQL

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=306, Percent_Identity=59.8039215686275, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI7657641, Length=332, Percent_Identity=26.5060240963855, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1788589, Length=345, Percent_Identity=27.8260869565217, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI48994969, Length=335, Percent_Identity=26.2686567164179, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=25, Blast_Score=88, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17539532, Length=307, Percent_Identity=57.9804560260586, Blast_Score=387, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17568069, Length=331, Percent_Identity=26.8882175226586, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI115532424, Length=326, Percent_Identity=26.3803680981595, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21356223, Length=307, Percent_Identity=57.328990228013, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI19923002, Length=347, Percent_Identity=23.9193083573487, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35418; Mature: 35418

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPTRNLVTGGAGFLGSHLVDRLMQADEEVICLDNYFTGRKVNLAQWIEHPRFELIRHDV
CCCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHCCHHHHHHHHCC
TEPIKLEVDRIWHLACPASPVHYQFNPIKTAKTSFLGTYNMLGLARRVGARLLLASTSEV
CCCCEEEHHHEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHH
YGDPEINPQPESYRGCVNTIGIRSCYDEGKRIAETLCFDYQRIHATEIRVMRIFNTYGPR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLPDDGRVVSNFIMQALRGEPLTLYGDGLQTRSFCYVDDLIEGMLRLMNSDTTGPINIGN
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCC
PSEFTIRQLAELVRNSIQPNLPLISKPLPQDDPMQRQPIIDLAKKELDWEPLIQLEDGLT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCHH
RTIDWFRKQL
HHHHHHHHCC
>Mature Secondary Structure
MQPTRNLVTGGAGFLGSHLVDRLMQADEEVICLDNYFTGRKVNLAQWIEHPRFELIRHDV
CCCCCCHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHCCHHHHHHHHCC
TEPIKLEVDRIWHLACPASPVHYQFNPIKTAKTSFLGTYNMLGLARRVGARLLLASTSEV
CCCCEEEHHHEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHH
YGDPEINPQPESYRGCVNTIGIRSCYDEGKRIAETLCFDYQRIHATEIRVMRIFNTYGPR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MLPDDGRVVSNFIMQALRGEPLTLYGDGLQTRSFCYVDDLIEGMLRLMNSDTTGPINIGN
CCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCC
PSEFTIRQLAELVRNSIQPNLPLISKPLPQDDPMQRQPIIDLAKKELDWEPLIQLEDGLT
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCHH
RTIDWFRKQL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]