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The map label for this gene is 33864077

Identifier: 33864077

GI number: 33864077

Start: 1911797

End: 1913872

Strand: Reverse

Name: 33864077

Synonym: PMT1810

Alternate gene names: NA

Gene position: 1913872-1911797 (Counterclockwise)

Preceding gene: 33864078

Following gene: 33864076

Centisome position: 79.39

GC content: 43.79

Gene sequence:

>2076_bases
GTGAATCCAGAAGAAATCATCCAGCAGCAGCAGGCAGCAGTGAAGGCATATCAGAGTAAGGATCTTGATGCTGCTGAGGC
TATTTGTATACAGATCCTTTCAGTGAATCCCAAGGAACCTAATTCATTGCATCTTCTTGGCTGTATTTATAAAGATCGTG
GAAATCTGCAACAAGCTTTTGATTTAATACAGGCTTCTATTCGAGAAGATGATAGTACTCCGATCCCGTTTATAAATCTG
GGGAATATCCTTGTCATGGTTGGCCAGCATGAGGAAGCTGCTCGTATCTTTCAGCAGTCATTGCAGCGGAATCAGCAGAT
TCCAGAATCTTGGTTTTGTTTTGGAAATGCTCTAAGGGAGATTGGGAATGTCCAAGAGGCCAAGCAGGCGTATAGGAATA
CTTTGCAACTCAATGCTGCTCATGCTGGTGCGGCAAGCATCCTTGGAGCACTCTTAGCTGACGAAGAGAAGCTGGATGAA
TCTGAAGAGATATTTTCTAAAGCAATAGAAGCAAGCCCTCAAGATGTGAATCTAAGAATTAACTATGGCAAGTTGTTGGA
GGATAAGTATGAGTACAACGCTGCTTTAGAGCAATATCGTTTTGCTCTGCTTCTCGCGCCTGAGTCTCCAGAGCTGCACC
TCAACTTTGCAAGTGCTCTTAAAAAGGAGGGAAAGGTTGAGGAAGCGATCGCAAGTTGTCGGAATGCGATTGAGTTGAGG
CCCGATTTTGAAGCTGCGTATTTTGGATTAGGGATTGTATTGAAAGAGAATGGAGAGTTTGAGGAGGCGAAAGCTAGTTA
TCGGAAAGCGATCGATTTGAAGCCAGATTTTGCGGATGCGTATTTGAATTTAGGGCATGTATTCAAAGATCATGGAGAAG
CAGAGGAAGCGAAAGCTAGTTATCGGACAGCGATCGATTTGAAGCCAGACTTTGCGGATGCGTATTTGAATTTAGGCAAT
ATCTTGAAAGAGGAGGGAGACGTCGAGGAAGCGATTGCGAGTTATCGGAAGGCGATCGAGTTGAAGCCTGACTTTGTGGA
TGCTTATTTGAATCTGGGCACAGTGTTGAATGATGAGGGAGAGGTTGAGGAGGCACGGCAAATCGTTTCTGCTCTCTATA
ATTTGAATGTAATTGAGGAATCATCTTTGCTGGTTACCTCCTCCAGTAATTTGGTTTTGGATTGGCATCAAAGGAAGGTA
TTGAATCTTTCGTTGGAAGTGGAGAGTGCTTCTCTTTTTTATGGCTTTAAGCCATTCTCTGCCTTCGAGGTTGTTAAAAC
AGTCGATGCTTGGCATTTTCCTCCTTTGTTTTTGAAAGGAGAAGGTGATAGGGCAAATGAAAAGCACTTGTATCGAAATG
GGTATCTGGTAGAAGATGAGATATTGCCAGAAGATTTATGTGCTGAGTTTGTAAATGGGTTTGAGGGTGCCAATGCGATG
AGTGCAGCGTTGATCCGTGCGGTATCTGAGAAGGGCGTCTTAGGTTCTGTCTTGGGGAAAATATTTAAACACACTGATTT
TCCACACTTGGTATGGAATTGTATTTACTTTGCCAAGGGACCTGATGATCAGGCTATCTCTGATGCATGGCATTACGACA
ATCATTATAATGTTTGGACCCCAAAATTAATGATTTACCTTAATTCTCAGCGAGAAGAGGGTGGGGCTACGGAATTTGTT
GATGCGTCTCTATCTAGAAGATTGTCAGAGGAAACAGATTATATGGGTCTTATTTGGCAGCGTGAGTCATATGCTGATCG
AGTAAAAGGATCGGTAAAAGACCTAGGTCTTGATCCTGCCACGTTGGATCCCGACCATTACACTTTCTCTCCAGATCATG
CAGGATCAGGTGTGTGGTTTTGCCCTTCCAGGGTTCTGCATCGAGGGGTAAGTCCAAAGAAAGGTGTAAGGCATGTGCTC
TCTTTTTCGTTGACTCCTCTGCCACATGATTGCGGCTGGTCTATTGATCAGTGTGTCGATAAGTCAATTGAGATTCTGCA
GGACAAAATAAATAAGGGTATGCAGAAGTCTGATGTCAATCCCTATTGGATTCCCGCTGAGGCTGGCTACGCATAA

Upstream 100 bases:

>100_bases
TCATTAGAGATGTATCTGTCGTTGAAGGTGTTGCTAGACCATCAGGAAGTGATGCAAGGCATGAAGTTGTCGTAAAATAG
TAAGAAGCAGGAGCTGCCTG

Downstream 100 bases:

>100_bases
GCCAGAAACCAAACCGCAAACCAGGAAAGTCTGCGAATTTTTCCTCCTCTGAAGGTTGTTTGTTGGTGGGAGCTACAGAT
AGCTACTGGAGAAGGGCATC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MNPEEIIQQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAFDLIQASIREDDSTPIPFINL
GNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALREIGNVQEAKQAYRNTLQLNAAHAGAASILGALLADEEKLDE
SEEIFSKAIEASPQDVNLRINYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEAIASCRNAIELR
PDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEAKASYRTAIDLKPDFADAYLNLGN
ILKEEGDVEEAIASYRKAIELKPDFVDAYLNLGTVLNDEGEVEEARQIVSALYNLNVIEESSLLVTSSSNLVLDWHQRKV
LNLSLEVESASLFYGFKPFSAFEVVKTVDAWHFPPLFLKGEGDRANEKHLYRNGYLVEDEILPEDLCAEFVNGFEGANAM
SAALIRAVSEKGVLGSVLGKIFKHTDFPHLVWNCIYFAKGPDDQAISDAWHYDNHYNVWTPKLMIYLNSQREEGGATEFV
DASLSRRLSEETDYMGLIWQRESYADRVKGSVKDLGLDPATLDPDHYTFSPDHAGSGVWFCPSRVLHRGVSPKKGVRHVL
SFSLTPLPHDCGWSIDQCVDKSIEILQDKINKGMQKSDVNPYWIPAEAGYA

Sequences:

>Translated_691_residues
MNPEEIIQQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAFDLIQASIREDDSTPIPFINL
GNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALREIGNVQEAKQAYRNTLQLNAAHAGAASILGALLADEEKLDE
SEEIFSKAIEASPQDVNLRINYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEAIASCRNAIELR
PDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEAKASYRTAIDLKPDFADAYLNLGN
ILKEEGDVEEAIASYRKAIELKPDFVDAYLNLGTVLNDEGEVEEARQIVSALYNLNVIEESSLLVTSSSNLVLDWHQRKV
LNLSLEVESASLFYGFKPFSAFEVVKTVDAWHFPPLFLKGEGDRANEKHLYRNGYLVEDEILPEDLCAEFVNGFEGANAM
SAALIRAVSEKGVLGSVLGKIFKHTDFPHLVWNCIYFAKGPDDQAISDAWHYDNHYNVWTPKLMIYLNSQREEGGATEFV
DASLSRRLSEETDYMGLIWQRESYADRVKGSVKDLGLDPATLDPDHYTFSPDHAGSGVWFCPSRVLHRGVSPKKGVRHVL
SFSLTPLPHDCGWSIDQCVDKSIEILQDKINKGMQKSDVNPYWIPAEAGYA
>Mature_691_residues
MNPEEIIQQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAFDLIQASIREDDSTPIPFINL
GNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALREIGNVQEAKQAYRNTLQLNAAHAGAASILGALLADEEKLDE
SEEIFSKAIEASPQDVNLRINYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEAIASCRNAIELR
PDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEAKASYRTAIDLKPDFADAYLNLGN
ILKEEGDVEEAIASYRKAIELKPDFVDAYLNLGTVLNDEGEVEEARQIVSALYNLNVIEESSLLVTSSSNLVLDWHQRKV
LNLSLEVESASLFYGFKPFSAFEVVKTVDAWHFPPLFLKGEGDRANEKHLYRNGYLVEDEILPEDLCAEFVNGFEGANAM
SAALIRAVSEKGVLGSVLGKIFKHTDFPHLVWNCIYFAKGPDDQAISDAWHYDNHYNVWTPKLMIYLNSQREEGGATEFV
DASLSRRLSEETDYMGLIWQRESYADRVKGSVKDLGLDPATLDPDHYTFSPDHAGSGVWFCPSRVLHRGVSPKKGVRHVL
SFSLTPLPHDCGWSIDQCVDKSIEILQDKINKGMQKSDVNPYWIPAEAGYA

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=360, Percent_Identity=31.9444444444444, Blast_Score=186, Evalue=5e-47,
Organism=Homo sapiens, GI32307150, Length=360, Percent_Identity=31.9444444444444, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI118766330, Length=268, Percent_Identity=29.4776119402985, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI118766328, Length=268, Percent_Identity=29.4776119402985, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI301336134, Length=204, Percent_Identity=32.3529411764706, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI83415184, Length=204, Percent_Identity=32.3529411764706, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI22749211, Length=201, Percent_Identity=31.3432835820896, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI224809432, Length=241, Percent_Identity=25.7261410788382, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI25952122, Length=356, Percent_Identity=22.1910112359551, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI170784867, Length=212, Percent_Identity=29.2452830188679, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI167466177, Length=210, Percent_Identity=24.2857142857143, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI167466175, Length=210, Percent_Identity=24.2857142857143, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532690, Length=393, Percent_Identity=30.0254452926209, Blast_Score=169, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI115532692, Length=360, Percent_Identity=30.5555555555556, Blast_Score=166, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI25147174, Length=214, Percent_Identity=22.4299065420561, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25146105, Length=209, Percent_Identity=24.4019138755981, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319589, Length=267, Percent_Identity=26.2172284644195, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319387, Length=202, Percent_Identity=24.7524752475248, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17647755, Length=360, Percent_Identity=31.3888888888889, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24585827, Length=360, Percent_Identity=31.3888888888889, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24585829, Length=360, Percent_Identity=31.3888888888889, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24647123, Length=172, Percent_Identity=31.3953488372093, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656717, Length=329, Percent_Identity=27.355623100304, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI18110006, Length=329, Percent_Identity=27.355623100304, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24581187, Length=337, Percent_Identity=24.0356083086053, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281364285, Length=337, Percent_Identity=24.0356083086053, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161076610, Length=327, Percent_Identity=24.4648318042813, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920486, Length=327, Percent_Identity=24.4648318042813, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24659892, Length=278, Percent_Identity=22.3021582733813, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584835, Length=114, Percent_Identity=34.2105263157895, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 77371; Mature: 77371

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPEEIIQQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAF
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCCCCEEEEEEEECCCCCHHHHH
DLIQASIREDDSTPIPFINLGNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALRE
HHHHHHHCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IGNVQEAKQAYRNTLQLNAAHAGAASILGALLADEEKLDESEEIFSKAIEASPQDVNLRI
HCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCHHHCCHHHHHHHHHHHCCCCCEEEEE
NYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEAIASCRNAIELR
ECHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHEECC
PDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEAKAS
CCCCHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
YRTAIDLKPDFADAYLNLGNILKEEGDVEEAIASYRKAIELKPDFVDAYLNLGTVLNDEG
HHEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCC
EVEEARQIVSALYNLNVIEESSLLVTSSSNLVLDWHQRKVLNLSLEVESASLFYGFKPFS
CHHHHHHHHHHHHCCCEEECCCEEEECCCCEEEEECCCEEEEEEEEEECCEEEECCCCHH
AFEVVKTVDAWHFPPLFLKGEGDRANEKHLYRNGYLVEDEILPEDLCAEFVNGFEGANAM
HHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCEEEECCCCCHHHHHHHHHCCCCCHHH
SAALIRAVSEKGVLGSVLGKIFKHTDFPHLVWNCIYFAKGPDDQAISDAWHYDNHYNVWT
HHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCHHHHHHCCCCCCCEEC
PKLMIYLNSQREEGGATEFVDASLSRRLSEETDYMGLIWQRESYADRVKGSVKDLGLDPA
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCHHHCCCCCC
TLDPDHYTFSPDHAGSGVWFCPSRVLHRGVSPKKGVRHVLSFSLTPLPHDCGWSIDQCVD
CCCCCCCEECCCCCCCCEEECCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
KSIEILQDKINKGMQKSDVNPYWIPAEAGYA
HHHHHHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MNPEEIIQQQQAAVKAYQSKDLDAAEAICIQILSVNPKEPNSLHLLGCIYKDRGNLQQAF
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCCCCCCEEEEEEEECCCCCHHHHH
DLIQASIREDDSTPIPFINLGNILVMVGQHEEAARIFQQSLQRNQQIPESWFCFGNALRE
HHHHHHHCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IGNVQEAKQAYRNTLQLNAAHAGAASILGALLADEEKLDESEEIFSKAIEASPQDVNLRI
HCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCHHHCCHHHHHHHHHHHCCCCCEEEEE
NYGKLLEDKYEYNAALEQYRFALLLAPESPELHLNFASALKKEGKVEEAIASCRNAIELR
ECHHHHHHHHHHHHHHHHCEEEEEECCCCCCEEEEHHHHHHHCCCHHHHHHHHHHHEECC
PDFEAAYFGLGIVLKENGEFEEAKASYRKAIDLKPDFADAYLNLGHVFKDHGEAEEAKAS
CCCCHHHEEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
YRTAIDLKPDFADAYLNLGNILKEEGDVEEAIASYRKAIELKPDFVDAYLNLGTVLNDEG
HHEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCEECCCC
EVEEARQIVSALYNLNVIEESSLLVTSSSNLVLDWHQRKVLNLSLEVESASLFYGFKPFS
CHHHHHHHHHHHHCCCEEECCCEEEECCCCEEEEECCCEEEEEEEEEECCEEEECCCCHH
AFEVVKTVDAWHFPPLFLKGEGDRANEKHLYRNGYLVEDEILPEDLCAEFVNGFEGANAM
HHHHHHHHHHCCCCCEEEECCCCCCCCCCEEECCEEEECCCCCHHHHHHHHHCCCCCHHH
SAALIRAVSEKGVLGSVLGKIFKHTDFPHLVWNCIYFAKGPDDQAISDAWHYDNHYNVWT
HHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCCCCCHHHHHHCCCCCCCEEC
PKLMIYLNSQREEGGATEFVDASLSRRLSEETDYMGLIWQRESYADRVKGSVKDLGLDPA
CEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCHHHCCCCCC
TLDPDHYTFSPDHAGSGVWFCPSRVLHRGVSPKKGVRHVLSFSLTPLPHDCGWSIDQCVD
CCCCCCCEECCCCCCCCEEECCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
KSIEILQDKINKGMQKSDVNPYWIPAEAGYA
HHHHHHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]