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The map label for this gene is 33864075

Identifier: 33864075

GI number: 33864075

Start: 1908794

End: 1909501

Strand: Reverse

Name: 33864075

Synonym: PMT1808

Alternate gene names: NA

Gene position: 1909501-1908794 (Counterclockwise)

Preceding gene: 33864076

Following gene: 33864074

Centisome position: 79.2

GC content: 56.5

Gene sequence:

>708_bases
TTGCATTGTCTCTTCTGCAAGCAGCCTTGTCAGACTTGGGCGAAGAAGGTTGTTGTTCCAGCCACGCCCATAGCCACCCA
CCGCATCGCCAAGGATTTCCCAGCTCTATCTCAATCCTTCTTCTGCCGCCCTGCAGAGGTGGTGGGACCTGAGCTGGTGG
GCTGCAGGTTGGCGAAACGCCAAGAGGATGGAAGTTTGCTTTGGGGCGTGATTGTGGAAACGGAGGCGTATTCCCAGGAT
GAACCTGCCTGCCACGGCTACCGCAGGCGTTCGCCGCAGAACGAAACGCTGTTTGGTGAGCCAGGGCGGTTTTATGTGTA
TGTGAGCTATGGCATTCACCACTGCGTGAATGTGGTCACCGATCGTGCCGAATGGGCCAATGGTGTTTTGTTGAGGGCGA
TTGCACTTCCGGATGAACCGGAACGCGTAGCAGCGGGGCCCGCTTTATTGGCGCGTCGTTTTGGTTTGGATCCCTCCCAT
GACAGAGCAGCCGTTACAGGAGAGAATGACGTGTGGCTGGCAACTAGGCCGGCTACCTTCGGTACGCCAACGATTGTGAG
CACAACCAGGATCGGTATCTCTCAAGGACAGGATCTTCCTTGGCGTTGGTATCTCAAGAACTGTCGCAGTATTAGTCGCC
GTGCCAAGGGAGATCGCACGCCGCCTTTGCAACAAGCCTGGGCTCCTGTTGCCAGTGATGGCCAATGA

Upstream 100 bases:

>100_bases
AGCTACTGGAGAAGGGCATCGTCAATGCAAGACGCCTCTACAACTCAGGTCGCCTTATGAGTTTCCGTCGCTTCTGACAT
CAGAGCAAGGGCTTCGTTCA

Downstream 100 bases:

>100_bases
GCGGCTGGTCTCATCGTCACATCCTTGATCTGGCCAGCTTCTCCCTTGAGGATTACAGCTCTGTTCTGGAGTTAGCGCAT
CGCTTCCGCTCCATGCCAGT

Product: methylpurine-DNA glycosylase (MPG)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MHCLFCKQPCQTWAKKVVVPATPIATHRIAKDFPALSQSFFCRPAEVVGPELVGCRLAKRQEDGSLLWGVIVETEAYSQD
EPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDPSH
DRAAVTGENDVWLATRPATFGTPTIVSTTRIGISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASDGQ

Sequences:

>Translated_235_residues
MHCLFCKQPCQTWAKKVVVPATPIATHRIAKDFPALSQSFFCRPAEVVGPELVGCRLAKRQEDGSLLWGVIVETEAYSQD
EPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDPSH
DRAAVTGENDVWLATRPATFGTPTIVSTTRIGISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASDGQ
>Mature_235_residues
MHCLFCKQPCQTWAKKVVVPATPIATHRIAKDFPALSQSFFCRPAEVVGPELVGCRLAKRQEDGSLLWGVIVETEAYSQD
EPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDPSH
DRAAVTGENDVWLATRPATFGTPTIVSTTRIGISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASDGQ

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=167, Percent_Identity=29.940119760479, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI62632765, Length=167, Percent_Identity=29.940119760479, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI62632771, Length=167, Percent_Identity=29.940119760479, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 26108; Mature: 26108

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCLFCKQPCQTWAKKVVVPATPIATHRIAKDFPALSQSFFCRPAEVVGPELVGCRLAKR
CCCEECCHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHCC
QEDGSLLWGVIVETEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVT
CCCCCEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCEECCCCCEEEEEEHHHHHHHHHHH
DRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDPSHDRAAVTGENDVWLATRPATF
HHHHHHCCEEEEEEECCCCCHHHHCCHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCC
GTPTIVSTTRIGISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASDGQ
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MHCLFCKQPCQTWAKKVVVPATPIATHRIAKDFPALSQSFFCRPAEVVGPELVGCRLAKR
CCCEECCHHHHHHHHCEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHCC
QEDGSLLWGVIVETEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGIHHCVNVVT
CCCCCEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCEECCCCCEEEEEEHHHHHHHHHHH
DRAEWANGVLLRAIALPDEPERVAAGPALLARRFGLDPSHDRAAVTGENDVWLATRPATF
HHHHHHCCEEEEEEECCCCCHHHHCCHHHHHHHHCCCCCCCCEEEECCCCEEEEECCCCC
GTPTIVSTTRIGISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASDGQ
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA