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The map label for this gene is alr [H]

Identifier: 33864030

GI number: 33864030

Start: 1852940

End: 1854136

Strand: Direct

Name: alr [H]

Synonym: PMT1763

Alternate gene names: 33864030

Gene position: 1852940-1854136 (Clockwise)

Preceding gene: 33864028

Following gene: 33864032

Centisome position: 76.86

GC content: 55.72

Gene sequence:

>1197_bases
ATGCGAGACCTGATCGCCCCACACGGTGATCTACCTAGGGGCAAAAACCCTGAGCAGATTGCAAAAGCCGATCCACGTCA
GCGCGCCTGGGTGGAAGTTAACCCCGCAGCTGTGGAAGCCAATTGCCGCAGCCTTCGGAGACACCTTTGTGAAAGTTGTG
CCCTGATGGCCGTGGTGAAAGCTGATGGCTATGGCCATGGCGCTTTAACCGTAGCCCGAGCCGCCTTGCAAGGAGGAGCA
AAAAGCCTTGGAGTAGCAACCCTCCAAGAAGGGATTGAGCTTCGTCAAGCCGGCCACAATGCCCCAGTGCTTGTGCTAGG
CAATCTCACCCATAGCGAAGACCTGAAAGCTTGCCTCCATTGGCAACTCATGCCCACCCTCAGCAGTATGCGAGAGGCTC
TGCTCTGCCAAAACCTTGCAGATGGCAGCGGCCGGCAATTCAGGATTCAGCTCAAAATCGATACTGGGATGACCCGCCTC
GGCTGCGAGCTAAAGGAAGCTCCCATGCTGGTGGAGGCGATAGGCCACCTCAATCAACTGGAATTAAAGGGTATCTATAG
CCATTTAGCCCTGGCAGATGGGGATCTCCAAGGGAAAGCCGCAATGGTGACGGATCAGCAGCAGCAACACTTTGAGACGG
TGCTAAGAACGCTGCCAGAGCAACACAATGGATTTACGCGGCACCTTGCCAACTCCGCCGGCACCCTTCGCGATCGCGGA
CTCCACTACGACATGGTGCGCGTTGGTCTTGCTCTGTATGGCCACAGCCCCAACCTCCAACTACAAGGAAAAGTAGACCT
TCAGCCAGCTCTCAGCGTCAAAGCAAGGGTGACATTGATAAGGGATGTGCCTGCAGGTGTGGGAGTGAGTTACGGCCATC
GCTTCACCACACGACGCCCCAGTCGCCTAGCAGTCGTAGGAATCGGCTATGCCGACGGGGTTAGCCGATCCCTATCAGGC
CAAATCTCTGCCATAGCCGATGGTCAGCTTCTCCCACAGGTTGGCGCCATCACCATGGATCAACTCGTGCTTGATGCCAC
AAATCATCCCGACCTAGAGGTGGGAAGCATCGTGACCCTCCTAGGCAAGGACGGTGACGCCTGTATTACACCACAACAAT
GGAGTGATCTGAGTGGATCAATTCCATGGGAGGTGCTCTGCAGCTTCAAACATCGACTACCCAGACTGGTGATTTGA

Upstream 100 bases:

>100_bases
CGCGTTGAGTACGAGAACCTGGCTCATGCCAGCCCCCTGATTAAGCGCCATGCTACCGACACTCCAAGGGTGAGGTGATT
CCCTTGTTTACCCTGCCAGC

Downstream 100 bases:

>100_bases
CACCAAACCCAGACAACTAAAACAAAGCACTAGAGGTGGGTATTGGTAGGGTATGTAGGCCGCTGGAGAGGTGGCCGAGT
GGTTGAAGGCGGCTCCCTGC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRDLIAPHGDLPRGKNPEQIAKADPRQRAWVEVNPAAVEANCRSLRRHLCESCALMAVVKADGYGHGALTVARAALQGGA
KSLGVATLQEGIELRQAGHNAPVLVLGNLTHSEDLKACLHWQLMPTLSSMREALLCQNLADGSGRQFRIQLKIDTGMTRL
GCELKEAPMLVEAIGHLNQLELKGIYSHLALADGDLQGKAAMVTDQQQQHFETVLRTLPEQHNGFTRHLANSAGTLRDRG
LHYDMVRVGLALYGHSPNLQLQGKVDLQPALSVKARVTLIRDVPAGVGVSYGHRFTTRRPSRLAVVGIGYADGVSRSLSG
QISAIADGQLLPQVGAITMDQLVLDATNHPDLEVGSIVTLLGKDGDACITPQQWSDLSGSIPWEVLCSFKHRLPRLVI

Sequences:

>Translated_398_residues
MRDLIAPHGDLPRGKNPEQIAKADPRQRAWVEVNPAAVEANCRSLRRHLCESCALMAVVKADGYGHGALTVARAALQGGA
KSLGVATLQEGIELRQAGHNAPVLVLGNLTHSEDLKACLHWQLMPTLSSMREALLCQNLADGSGRQFRIQLKIDTGMTRL
GCELKEAPMLVEAIGHLNQLELKGIYSHLALADGDLQGKAAMVTDQQQQHFETVLRTLPEQHNGFTRHLANSAGTLRDRG
LHYDMVRVGLALYGHSPNLQLQGKVDLQPALSVKARVTLIRDVPAGVGVSYGHRFTTRRPSRLAVVGIGYADGVSRSLSG
QISAIADGQLLPQVGAITMDQLVLDATNHPDLEVGSIVTLLGKDGDACITPQQWSDLSGSIPWEVLCSFKHRLPRLVI
>Mature_398_residues
MRDLIAPHGDLPRGKNPEQIAKADPRQRAWVEVNPAAVEANCRSLRRHLCESCALMAVVKADGYGHGALTVARAALQGGA
KSLGVATLQEGIELRQAGHNAPVLVLGNLTHSEDLKACLHWQLMPTLSSMREALLCQNLADGSGRQFRIQLKIDTGMTRL
GCELKEAPMLVEAIGHLNQLELKGIYSHLALADGDLQGKAAMVTDQQQQHFETVLRTLPEQHNGFTRHLANSAGTLRDRG
LHYDMVRVGLALYGHSPNLQLQGKVDLQPALSVKARVTLIRDVPAGVGVSYGHRFTTRRPSRLAVVGIGYADGVSRSLSG
QISAIADGQLLPQVGAITMDQLVLDATNHPDLEVGSIVTLLGKDGDACITPQQWSDLSGSIPWEVLCSFKHRLPRLVI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=28.1842818428184, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790487, Length=347, Percent_Identity=31.9884726224784, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43022; Mature: 43022

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS00395 ALANINE_RACEMASE ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLIAPHGDLPRGKNPEQIAKADPRQRAWVEVNPAAVEANCRSLRRHLCESCALMAVVK
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHEEEEE
ADGYGHGALTVARAALQGGAKSLGVATLQEGIELRQAGHNAPVLVLGNLTHSEDLKACLH
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
WQLMPTLSSMREALLCQNLADGSGRQFRIQLKIDTGMTRLGCELKEAPMLVEAIGHLNQL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHCCCHHHCCHHHHHHCCCCHH
ELKGIYSHLALADGDLQGKAAMVTDQQQQHFETVLRTLPEQHNGFTRHLANSAGTLRDRG
HHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHCCHHCCCHHHHHHCCCCCHHHCC
LHYDMVRVGLALYGHSPNLQLQGKVDLQPALSVKARVTLIRDVPAGVGVSYGHRFTTRRP
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCC
SRLAVVGIGYADGVSRSLSGQISAIADGQLLPQVGAITMDQLVLDATNHPDLEVGSIVTL
CEEEEEEECCHHCCCHHCCCCEEEEECCCCCCHHCCHHHHHHHEECCCCCCCCHHHEEEE
LGKDGDACITPQQWSDLSGSIPWEVLCSFKHRLPRLVI
ECCCCCEEECCHHCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRDLIAPHGDLPRGKNPEQIAKADPRQRAWVEVNPAAVEANCRSLRRHLCESCALMAVVK
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHEEEEE
ADGYGHGALTVARAALQGGAKSLGVATLQEGIELRQAGHNAPVLVLGNLTHSEDLKACLH
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
WQLMPTLSSMREALLCQNLADGSGRQFRIQLKIDTGMTRLGCELKEAPMLVEAIGHLNQL
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHCCCHHHCCHHHHHHCCCCHH
ELKGIYSHLALADGDLQGKAAMVTDQQQQHFETVLRTLPEQHNGFTRHLANSAGTLRDRG
HHHHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHCCHHCCCHHHHHHCCCCCHHHCC
LHYDMVRVGLALYGHSPNLQLQGKVDLQPALSVKARVTLIRDVPAGVGVSYGHRFTTRRP
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCC
SRLAVVGIGYADGVSRSLSGQISAIADGQLLPQVGAITMDQLVLDATNHPDLEVGSIVTL
CEEEEEEECCHHCCCHHCCCCEEEEECCCCCCHHCCHHHHHHHEECCCCCCCCHHHEEEE
LGKDGDACITPQQWSDLSGSIPWEVLCSFKHRLPRLVI
ECCCCCEEECCHHCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]