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The map label for this gene is BioD [H]

Identifier: 33863758

GI number: 33863758

Start: 1576005

End: 1576673

Strand: Direct

Name: BioD [H]

Synonym: PMT1491

Alternate gene names: 33863758

Gene position: 1576005-1576673 (Clockwise)

Preceding gene: 33863757

Following gene: 33863760

Centisome position: 65.37

GC content: 53.36

Gene sequence:

>669_bases
ATGACTGAGGCAACGACTCCTCTAATCGTCTGCGGCACAGACACCAACGTCGGCAAGACCGTGGTGAGTGCATTGCTAGT
GCAAGGATTAGTTGCCACCTACTGGAAGCCAATACAGAGCGGCCTTGAGGAAGACGGTGGAGACCGCAATAGGGTTTGTC
GGCTCCTTGATCTTCCCGCCGAACGTTGGCACCCAGAGGTCTATAACCTGCAGGCCGCAGTATCACCCCACTGGGCCGCA
GAACAAGAGAACTGCTACATCAACCCCGATCAACTTGTATTGCCTGATGTATCTGGTCCTGTAGTTATCGAAACTGCTGG
CGGCCTAATGGTGCCACTCAACCGTCAATGGCTACAACTCGATCAACTCGTGCGTTGGCAACTACCGCTAATCCTCGTTG
CACGCAGTGGCCTAGGTACTCTCAACCACACCCTACTCAGCCTTGAAGCACTGCGCTTACGCAATCTGAAGGTCTTAGGT
TTGGTGCTCAATGGTCCACCCCACCCCGACAATCCAAAAACCCTGGAACAATTTGGTGGTGTTCCAGTCATCGCTCAGTT
GCCTCACTTACCCAATCTGACGGCGGCAACACTCGCAGAGCAGTGGCATCTGCAAGACCTGAGCCTTACCTTCAAACGGC
TACTGAAATCCTGGAGTCAAGTTCAATGA

Upstream 100 bases:

>100_bases
GGGTTGGCAACTGGCGCCATCTCAAACAAGCCTGGCCACGTTGCCAGAACAGTGGAGATGCACAACTCACATGGCTGATC
CAACTGCTTTTAATCCAGCG

Downstream 100 bases:

>100_bases
ACAAGCGTCAGTCATGGGCCACAGTTGGAGTTGTTCTTCTCTGTGGAGGAATCCTTGTGCTATTCACCGACATAGAAGTC
GGCATGGTGCGCTGGGTCAA

Product: dethiobiotin synthase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTEATTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCRLLDLPAERWHPEVYNLQAAVSPHWAA
EQENCYINPDQLVLPDVSGPVVIETAGGLMVPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLG
LVLNGPPHPDNPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ

Sequences:

>Translated_222_residues
MTEATTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCRLLDLPAERWHPEVYNLQAAVSPHWAA
EQENCYINPDQLVLPDVSGPVVIETAGGLMVPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLG
LVLNGPPHPDNPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ
>Mature_221_residues
TEATTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCRLLDLPAERWHPEVYNLQAAVSPHWAAE
QENCYINPDQLVLPDVSGPVVIETAGGLMVPLNRQWLQLDQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLGL
VLNGPPHPDNPKTLEQFGGVPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=202, Percent_Identity=30.1980198019802, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324385, Length=197, Percent_Identity=39.5939086294416, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24524; Mature: 24392

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEATTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCRLLDLPA
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
ERWHPEVYNLQAAVSPHWAAEQENCYINPDQLVLPDVSGPVVIETAGGLMVPLNRQWLQL
HHCCCHHHEEEEECCCCCCCCCCCEEECCCCEEECCCCCCEEEEECCCEEEECCHHHHHH
DQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLGLVLNGPPHPDNPKTLEQFGG
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHCC
VPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEATTPLIVCGTDTNVGKTVVSALLVQGLVATYWKPIQSGLEEDGGDRNRVCRLLDLPA
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
ERWHPEVYNLQAAVSPHWAAEQENCYINPDQLVLPDVSGPVVIETAGGLMVPLNRQWLQL
HHCCCHHHEEEEECCCCCCCCCCCEEECCCCEEECCCCCCEEEEECCCEEEECCHHHHHH
DQLVRWQLPLILVARSGLGTLNHTLLSLEALRLRNLKVLGLVLNGPPHPDNPKTLEQFGG
HHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHCC
VPVIAQLPHLPNLTAATLAEQWHLQDLSLTFKRLLKSWSQVQ
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA