Click here to switch to the map view.

The map label for this gene is queF [H]

Identifier: 33863745

GI number: 33863745

Start: 1563410

End: 1563817

Strand: Reverse

Name: queF [H]

Synonym: PMT1478

Alternate gene names: 33863745

Gene position: 1563817-1563410 (Counterclockwise)

Preceding gene: 33863749

Following gene: 33863741

Centisome position: 64.87

GC content: 51.72

Gene sequence:

>408_bases
GTGAGCAGTACTCAAGCGCAGGCATCTAAAACCCTCTATGGCGAACGGGTGATTGCTGAGGGTGAGCTGATCTGCTTTGA
CAATCCGAGGCCTGAGCGGCCCTATGAGATCTCAATTGAGTTGCCTGAGTTCACCTGTCAATGTCCGTTCTCTGGGTATC
CCGACTTTGCTGTGCTACGTCTGCTTTATCAGCCAGGCTCGAGAGTGATTGAGCTCAAAGCGATCAAGCTCTATGTGAAT
AGCTATCGGAATTGCACGATTTCACATGAGGAGGCCGCAAACAAGATCCTTGATGATTTGGTTGTCGCCTGTAATCCGGT
CTGGATGCAATTAGAAGCAGATTTCAATCCGCGCGGCAATGTGCATACGGTGGTGCGGGTTAGCCATGGCAGTCGCCAGC
CCTGCTAG

Upstream 100 bases:

>100_bases
GTTGCTGCGGTTTGCGTTGACTCCGAAGCAGATTCTTTCTCCTCTAAGGCCGAGCTAGGAGTCGAGAGCTAGGGTCCGTT
TTAGGCATCGTTCCATCCCC

Downstream 100 bases:

>100_bases
TCACTTAGGCAATAGAGATGGCTGGTTTTATGCCCAGTCAGATTGATAGCGTAATTTTGCTAAAGAGTCTTATGGCTTGA
AGATGGCGAGCAAGCCACTT

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MSSTQAQASKTLYGERVIAEGELICFDNPRPERPYEISIELPEFTCQCPFSGYPDFAVLRLLYQPGSRVIELKAIKLYVN
SYRNCTISHEEAANKILDDLVVACNPVWMQLEADFNPRGNVHTVVRVSHGSRQPC

Sequences:

>Translated_135_residues
MSSTQAQASKTLYGERVIAEGELICFDNPRPERPYEISIELPEFTCQCPFSGYPDFAVLRLLYQPGSRVIELKAIKLYVN
SYRNCTISHEEAANKILDDLVVACNPVWMQLEADFNPRGNVHTVVRVSHGSRQPC
>Mature_134_residues
SSTQAQASKTLYGERVIAEGELICFDNPRPERPYEISIELPEFTCQCPFSGYPDFAVLRLLYQPGSRVIELKAIKLYVNS
YRNCTISHEEAANKILDDLVVACNPVWMQLEADFNPRGNVHTVVRVSHGSRQPC

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 15264; Mature: 15132

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTQAQASKTLYGERVIAEGELICFDNPRPERPYEISIELPEFTCQCPFSGYPDFAVLR
CCCCHHHHHHHHHCCEEEECCCEEEECCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHH
LLYQPGSRVIELKAIKLYVNSYRNCTISHEEAANKILDDLVVACNPVWMQLEADFNPRGN
HHHCCCCCEEEEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
VHTVVRVSHGSRQPC
EEEEEEECCCCCCCC
>Mature Secondary Structure 
SSTQAQASKTLYGERVIAEGELICFDNPRPERPYEISIELPEFTCQCPFSGYPDFAVLR
CCCHHHHHHHHHCCEEEECCCEEEECCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHH
LLYQPGSRVIELKAIKLYVNSYRNCTISHEEAANKILDDLVVACNPVWMQLEADFNPRGN
HHHCCCCCEEEEEEEEEEECCCCCEEECHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
VHTVVRVSHGSRQPC
EEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA