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The map label for this gene is ftsW [H]

Identifier: 33863742

GI number: 33863742

Start: 1559509

End: 1560756

Strand: Direct

Name: ftsW [H]

Synonym: PMT1475

Alternate gene names: 33863742

Gene position: 1559509-1560756 (Clockwise)

Preceding gene: 33863732

Following gene: 33863743

Centisome position: 64.69

GC content: 55.69

Gene sequence:

>1248_bases
TTGAGCAGCTCCTCCGTCCTATCCCGCCGGAGTCAAAAACAACGGCAAGGGGCATTACGGCTAAGCCGTAATGATGGAAG
CGATCAGTTGTCTTTCTGGCAAAAACGTCTCCCCCTCCCCTGGGCACTCTGGCCCGCTGAAGGCCGTTTACTACTTACCC
TTTTTGCCTTCTGGAGCCTGGCAGGGCTGATGGTGCTTGGCTCGGCTAGCTGGTGGGTAGCCACTCGAGAAATGGGAGAA
GGTGCTTATTACCTCAAACGACAACTGATATGGATGGCTGCCAGCTGGAGCCTGCTTGGCCTGGCTGTCTCTACCAGTCT
GCGCCGTTGGCTAAAACTTGCAGGACCAGCCCTCTGGCTCAGTTGCTTCCTCGTAGCAGCGACCCTAGTCATCGGTAGCA
CCGTCAATGGGGCCAGTCGCTGGTTAGTGATCGGCCCTCTCCAGATCCAACCATCAGAACTAGTCAAACCCTTTGTGGTG
CTGCAAGCCGCCAACCTGTTTGCCCACTGGCAGCGCATCAGATCAGATGAGAAATTGCTCTGGCTTGGCATCTTCGGGGC
CCTACTTCTACTGATTCTCAAACAGCCCAACCTCAGCACTGCCGCACTGACGGGCATGTTGTTATGGCTTATGGCACTGG
CCGCTGGTCTGAGGTTGCGCACTTTGCTGGCAACCGCCATGGCAGGCGGCCTGCTTGGCACAACCAGCATTCTGATCAAT
GAGTATCAGCGCATACGCGTGATCTCCTTCCTCGACCCATGGCAAGACCCACAAGGGAGTGGTTATCAGCTCGTACAAAG
CCTGCTTGCCATCGGCTCCGGGGGGTGGTTTGGCGAGGGCTTCGGCCTCTCCACCCAAAAACTGCAATACCTGCCCATAC
AAAGCACTGATTTCATCTATGCCGTTTTTGCCGAGGAATTTGGTTTCGTGGGCTCGGTGATGATGTTGCTCTTCCTGATG
TTGGTTGCTTTCCTCGGCCTAAGGGTAGCTCTGAGTTGCAGAACCAACCAGTCGCGATTGGTTGCTATCGGCTGCACAAC
GATCCTGGTGGGTCAAGCCGTGATCAATGTGGCCGTGGCCTCCGGCGTGATGCCCACAACCGGCTTGCCCTTGCCAATGG
TGAGTTATGGAGGCAATTCACTGCTCTCAAGCGTCATGATTGCCGGTCTTTTGATCCGTTGTTCCCTTGAATCAACAGGG
CTCCTTGGTGGCAGATCCCCTAGACAGCGACGTCAGTCGATAGGGTAA

Upstream 100 bases:

>100_bases
TTGTCCAATAATGTTTTAAGCAGTTTTTTGTTGTCAATTAAGACTTGGCAAAGTGCTATTAACACGTCTCAATAGGTCAA
CTTGACTAAGACCTCCCCTC

Downstream 100 bases:

>100_bases
ATACCGTAATTTGATCCGGCTGAACCGGCTCTACCCATCCCTGCTCTGGACCTGGTTCTCTCAGATCTAGCCCGCAACGG
TGAGCAAATGCTCAGCCACG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSSSSVLSRRSQKQRQGALRLSRNDGSDQLSFWQKRLPLPWALWPAEGRLLLTLFAFWSLAGLMVLGSASWWVATREMGE
GAYYLKRQLIWMAASWSLLGLAVSTSLRRWLKLAGPALWLSCFLVAATLVIGSTVNGASRWLVIGPLQIQPSELVKPFVV
LQAANLFAHWQRIRSDEKLLWLGIFGALLLLILKQPNLSTAALTGMLLWLMALAAGLRLRTLLATAMAGGLLGTTSILIN
EYQRIRVISFLDPWQDPQGSGYQLVQSLLAIGSGGWFGEGFGLSTQKLQYLPIQSTDFIYAVFAEEFGFVGSVMMLLFLM
LVAFLGLRVALSCRTNQSRLVAIGCTTILVGQAVINVAVASGVMPTTGLPLPMVSYGGNSLLSSVMIAGLLIRCSLESTG
LLGGRSPRQRRQSIG

Sequences:

>Translated_415_residues
MSSSSVLSRRSQKQRQGALRLSRNDGSDQLSFWQKRLPLPWALWPAEGRLLLTLFAFWSLAGLMVLGSASWWVATREMGE
GAYYLKRQLIWMAASWSLLGLAVSTSLRRWLKLAGPALWLSCFLVAATLVIGSTVNGASRWLVIGPLQIQPSELVKPFVV
LQAANLFAHWQRIRSDEKLLWLGIFGALLLLILKQPNLSTAALTGMLLWLMALAAGLRLRTLLATAMAGGLLGTTSILIN
EYQRIRVISFLDPWQDPQGSGYQLVQSLLAIGSGGWFGEGFGLSTQKLQYLPIQSTDFIYAVFAEEFGFVGSVMMLLFLM
LVAFLGLRVALSCRTNQSRLVAIGCTTILVGQAVINVAVASGVMPTTGLPLPMVSYGGNSLLSSVMIAGLLIRCSLESTG
LLGGRSPRQRRQSIG
>Mature_414_residues
SSSSVLSRRSQKQRQGALRLSRNDGSDQLSFWQKRLPLPWALWPAEGRLLLTLFAFWSLAGLMVLGSASWWVATREMGEG
AYYLKRQLIWMAASWSLLGLAVSTSLRRWLKLAGPALWLSCFLVAATLVIGSTVNGASRWLVIGPLQIQPSELVKPFVVL
QAANLFAHWQRIRSDEKLLWLGIFGALLLLILKQPNLSTAALTGMLLWLMALAAGLRLRTLLATAMAGGLLGTTSILINE
YQRIRVISFLDPWQDPQGSGYQLVQSLLAIGSGGWFGEGFGLSTQKLQYLPIQSTDFIYAVFAEEFGFVGSVMMLLFLML
VAFLGLRVALSCRTNQSRLVAIGCTTILVGQAVINVAVASGVMPTTGLPLPMVSYGGNSLLSSVMIAGLLIRCSLESTGL
LGGRSPRQRRQSIG

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=383, Percent_Identity=34.4647519582245, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1786853, Length=291, Percent_Identity=36.7697594501718, Blast_Score=142, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45220; Mature: 45089

Theoretical pI: Translated: 11.14; Mature: 11.14

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSSVLSRRSQKQRQGALRLSRNDGSDQLSFWQKRLPLPWALWPAEGRLLLTLFAFWSL
CCCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHH
AGLMVLGSASWWVATREMGEGAYYLKRQLIWMAASWSLLGLAVSTSLRRWLKLAGPALWL
HHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SCFLVAATLVIGSTVNGASRWLVIGPLQIQPSELVKPFVVLQAANLFAHWQRIRSDEKLL
HHHHHHHHHHHCCCCCCCCCEEEEECCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
WLGIFGALLLLILKQPNLSTAALTGMLLWLMALAAGLRLRTLLATAMAGGLLGTTSILIN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EYQRIRVISFLDPWQDPQGSGYQLVQSLLAIGSGGWFGEGFGLSTQKLQYLPIQSTDFIY
HHHHEEEEEHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEE
AVFAEEFGFVGSVMMLLFLMLVAFLGLRVALSCRTNQSRLVAIGCTTILVGQAVINVAVA
EEHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHH
SGVMPTTGLPLPMVSYGGNSLLSSVMIAGLLIRCSLESTGLLGGRSPRQRRQSIG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
SSSSVLSRRSQKQRQGALRLSRNDGSDQLSFWQKRLPLPWALWPAEGRLLLTLFAFWSL
CCHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHH
AGLMVLGSASWWVATREMGEGAYYLKRQLIWMAASWSLLGLAVSTSLRRWLKLAGPALWL
HHHHHHCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
SCFLVAATLVIGSTVNGASRWLVIGPLQIQPSELVKPFVVLQAANLFAHWQRIRSDEKLL
HHHHHHHHHHHCCCCCCCCCEEEEECCEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
WLGIFGALLLLILKQPNLSTAALTGMLLWLMALAAGLRLRTLLATAMAGGLLGTTSILIN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
EYQRIRVISFLDPWQDPQGSGYQLVQSLLAIGSGGWFGEGFGLSTQKLQYLPIQSTDFIY
HHHHEEEEEHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEE
AVFAEEFGFVGSVMMLLFLMLVAFLGLRVALSCRTNQSRLVAIGCTTILVGQAVINVAVA
EEHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHH
SGVMPTTGLPLPMVSYGGNSLLSSVMIAGLLIRCSLESTGLLGGRSPRQRRQSIG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]