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The map label for this gene is prmA

Identifier: 33863697

GI number: 33863697

Start: 1518113

End: 1519018

Strand: Reverse

Name: prmA

Synonym: PMT1430

Alternate gene names: 33863697

Gene position: 1519018-1518113 (Counterclockwise)

Preceding gene: 33863698

Following gene: 33863696

Centisome position: 63.01

GC content: 55.52

Gene sequence:

>906_bases
ATGAACTTTGCTGCTGCTCTTCGCTGGTGGCGTCTTTCTCTGCCTATTGCAGATGAGCTGGAAGAGTCGCTCATTTGGAA
GCTGACAGATCTGGGTCTCTGCCGACTTGCTGTTCAACATGCGCCTGAGAACTCTGAGCGCACTCTTTTGGCATGGTTGC
CATCGTCTGAGTGGTCTGAGTCGGACAGAGATCAGCTGATGGCCAACCTGCGTCCTCTGGCCGAACCGTTTGGCCTGAAA
TTAGCCAACCCCACTTGGTGCGAGGTGGCCGATGAAGACTGGAGTTTGAACTGGAAGCAAGATTGGCAACCCGATCCGGT
GGGGCAGCGTTTGTTGATCTTGCCGGCTTGGTTGGATCTGCCGCAGGAGTATGCCGATCGGTTTGTTGTGCGACTAGACC
CTGGCAGTGCTTTTGGCACTGGCAGCCACCCAAGCACTCGCCTTTGTCTGGAGGCGCTGGAAAGGAACCCACCGCTGGGC
TTGAGGGTTGCAGATCTCGGCTGTGGCAGTGGGGTGTTGGGTTTCGCCGCACTTGCTTTTGGAGCTAGACAGGTGCTGGC
CGCTGATACGGATTGCCAGGCTGTCTGCGCCTCTAGAGCTAATACAGAGCTCAATCAGCTCGATTTAGATCGTTTAAGGG
TTGTGCATGGTTCTGTGGAGGCTTTGTCAGCGCAGCTAGAGGGACAGACCGTCGACCTGCTGCTCTGCAACATCCTGGCG
CCTGTGATTGAGGTTTTGGCTCCAAGCTTTGATCAGTTGTTGAGTGCTAATGGTCGAGGTTTGCTCAGTGGTTTGCTGGT
GAAGCAAGCGCCAAGGCTTCAGATGGTTTTGGAGGCGCTGGGATGGCGGGTGAATTGCCTGACTGAGCAGGGCTGCTGGG
GGCTTTTAGATGTGTCTAAGCGGTAA

Upstream 100 bases:

>100_bases
GCATTGATGATCCAATTCCGCCCAGCTTGCTGGTCACCATCCATGCGATCAATGGCATTAAGGAAGCCCATCCGGTCACC
CTCTGATCAGGGCTGATGAG

Downstream 100 bases:

>100_bases
TTCTGCGCAAATTTTTATATAAGCCAGAGTTATCAGTACTCGTTCTTTGATTGGCCTTGGCCGGGCAGATTGCACGATCA
GACTGAATTTTTGCCGGGAG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNFAAALRWWRLSLPIADELEESLIWKLTDLGLCRLAVQHAPENSERTLLAWLPSSEWSESDRDQLMANLRPLAEPFGLK
LANPTWCEVADEDWSLNWKQDWQPDPVGQRLLILPAWLDLPQEYADRFVVRLDPGSAFGTGSHPSTRLCLEALERNPPLG
LRVADLGCGSGVLGFAALAFGARQVLAADTDCQAVCASRANTELNQLDLDRLRVVHGSVEALSAQLEGQTVDLLLCNILA
PVIEVLAPSFDQLLSANGRGLLSGLLVKQAPRLQMVLEALGWRVNCLTEQGCWGLLDVSKR

Sequences:

>Translated_301_residues
MNFAAALRWWRLSLPIADELEESLIWKLTDLGLCRLAVQHAPENSERTLLAWLPSSEWSESDRDQLMANLRPLAEPFGLK
LANPTWCEVADEDWSLNWKQDWQPDPVGQRLLILPAWLDLPQEYADRFVVRLDPGSAFGTGSHPSTRLCLEALERNPPLG
LRVADLGCGSGVLGFAALAFGARQVLAADTDCQAVCASRANTELNQLDLDRLRVVHGSVEALSAQLEGQTVDLLLCNILA
PVIEVLAPSFDQLLSANGRGLLSGLLVKQAPRLQMVLEALGWRVNCLTEQGCWGLLDVSKR
>Mature_301_residues
MNFAAALRWWRLSLPIADELEESLIWKLTDLGLCRLAVQHAPENSERTLLAWLPSSEWSESDRDQLMANLRPLAEPFGLK
LANPTWCEVADEDWSLNWKQDWQPDPVGQRLLILPAWLDLPQEYADRFVVRLDPGSAFGTGSHPSTRLCLEALERNPPLG
LRVADLGCGSGVLGFAALAFGARQVLAADTDCQAVCASRANTELNQLDLDRLRVVHGSVEALSAQLEGQTVDLLLCNILA
PVIEVLAPSFDQLLSANGRGLLSGLLVKQAPRLQMVLEALGWRVNCLTEQGCWGLLDVSKR

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=161, Percent_Identity=42.8571428571429, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PROMM (Q7TUS7)

Other databases:

- EMBL:   BX548175
- RefSeq:   NP_895257.1
- ProteinModelPortal:   Q7TUS7
- SMR:   Q7TUS7
- STRING:   Q7TUS7
- GeneID:   1729432
- GenomeReviews:   BX548175_GR
- KEGG:   pmt:PMT1430
- NMPDR:   fig|74547.1.peg.1424
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   MSFGTGY
- ProtClustDB:   PRK00517
- BioCyc:   PMAR74547:PMT1430-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33178; Mature: 33178

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFAAALRWWRLSLPIADELEESLIWKLTDLGLCRLAVQHAPENSERTLLAWLPSSEWSE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
SDRDQLMANLRPLAEPFGLKLANPTWCEVADEDWSLNWKQDWQPDPVGQRLLILPAWLDL
CHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEHHHCC
PQEYADRFVVRLDPGSAFGTGSHPSTRLCLEALERNPPLGLRVADLGCGSGVLGFAALAF
CHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHH
GARQVLAADTDCQAVCASRANTELNQLDLDRLRVVHGSVEALSAQLEGQTVDLLLCNILA
HHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH
PVIEVLAPSFDQLLSANGRGLLSGLLVKQAPRLQMVLEALGWRVNCLTEQGCWGLLDVSK
HHHHHHCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCEECEECCC
R
C
>Mature Secondary Structure
MNFAAALRWWRLSLPIADELEESLIWKLTDLGLCRLAVQHAPENSERTLLAWLPSSEWSE
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
SDRDQLMANLRPLAEPFGLKLANPTWCEVADEDWSLNWKQDWQPDPVGQRLLILPAWLDL
CHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEHHHCC
PQEYADRFVVRLDPGSAFGTGSHPSTRLCLEALERNPPLGLRVADLGCGSGVLGFAALAF
CHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHH
GARQVLAADTDCQAVCASRANTELNQLDLDRLRVVHGSVEALSAQLEGQTVDLLLCNILA
HHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHH
PVIEVLAPSFDQLLSANGRGLLSGLLVKQAPRLQMVLEALGWRVNCLTEQGCWGLLDVSK
HHHHHHCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCEECEECCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642