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The map label for this gene is rpfC [H]

Identifier: 33863623

GI number: 33863623

Start: 1441987

End: 1442403

Strand: Direct

Name: rpfC [H]

Synonym: PMT1356

Alternate gene names: 33863623

Gene position: 1441987-1442403 (Clockwise)

Preceding gene: 33863622

Following gene: 33863624

Centisome position: 59.81

GC content: 50.12

Gene sequence:

>417_bases
ATGAACCAAACCGATTCCCCTAATCGCATCGAAATATCTGGTAAGACCCAGCCTCTTACCGTGGCCATAGTGGATGACGA
TCCCAGAGTTCGTGAATTGCTCAAGGAGGAAATTCAAGACGAAGGTCATCACGTCTTGAGCTTTGAATCGGCCGAAACCT
TTCTTGAGAACAGCTCTTTGGAGAGCATTGATTTAGTTCTGCTGGACCTGATGATGCCAGGTATGAATGGGCTTGAATGC
CTGCAGCAACTGCATCAACAAGCTTGCCATGTCAAATTGCCGAGGATTGTTGTTGTATCCGCCCTCAGTGACCCAAGCAA
ACAGCGCCAGGCCCTCGAGGCCGGTGCTGAAAGCTATGTCATCAAACCCGACCTCTTCGAGAGACTTCCCACCCTCCTAA
ATGGATCCACACCCTGA

Upstream 100 bases:

>100_bases
TTTCCGAAAGGGCCGACCGAATGGCGCGCTTCCACGATGGTCAAGTCGTTCGGGACTGGAGCGCTGAGCTGGCTACTACT
GATATCAGATCAACAAAAGA

Downstream 100 bases:

>100_bases
AGGAGGGGCCCACGAATAACCATTGATTGCACAAGGTCTGGATCCAGACAAACTGCTTAAGTAGGCACCAGGTTGATTGC
ATGAATGACTAACGCATCAT

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MNQTDSPNRIEISGKTQPLTVAIVDDDPRVRELLKEEIQDEGHHVLSFESAETFLENSSLESIDLVLLDLMMPGMNGLEC
LQQLHQQACHVKLPRIVVVSALSDPSKQRQALEAGAESYVIKPDLFERLPTLLNGSTP

Sequences:

>Translated_138_residues
MNQTDSPNRIEISGKTQPLTVAIVDDDPRVRELLKEEIQDEGHHVLSFESAETFLENSSLESIDLVLLDLMMPGMNGLEC
LQQLHQQACHVKLPRIVVVSALSDPSKQRQALEAGAESYVIKPDLFERLPTLLNGSTP
>Mature_138_residues
MNQTDSPNRIEISGKTQPLTVAIVDDDPRVRELLKEEIQDEGHHVLSFESAETFLENSSLESIDLVLLDLMMPGMNGLEC
LQQLHQQACHVKLPRIVVVSALSDPSKQRQALEAGAESYVIKPDLFERLPTLLNGSTP

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=103, Percent_Identity=34.9514563106796, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1789809, Length=103, Percent_Identity=34.9514563106796, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI1786911, Length=103, Percent_Identity=33.0097087378641, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 15331; Mature: 15331

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTDSPNRIEISGKTQPLTVAIVDDDPRVRELLKEEIQDEGHHVLSFESAETFLENSSL
CCCCCCCCEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCC
ESIDLVLLDLMMPGMNGLECLQQLHQQACHVKLPRIVVVSALSDPSKQRQALEAGAESYV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHCCCCCEE
IKPDLFERLPTLLNGSTP
ECHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNQTDSPNRIEISGKTQPLTVAIVDDDPRVRELLKEEIQDEGHHVLSFESAETFLENSSL
CCCCCCCCEEEECCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCC
ESIDLVLLDLMMPGMNGLECLQQLHQQACHVKLPRIVVVSALSDPSKQRQALEAGAESYV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHCCCCCEE
IKPDLFERLPTLLNGSTP
ECHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]