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The map label for this gene is aapM [H]

Identifier: 33863166

GI number: 33863166

Start: 973956

End: 974939

Strand: Reverse

Name: aapM [H]

Synonym: PMT0894

Alternate gene names: 33863166

Gene position: 974939-973956 (Counterclockwise)

Preceding gene: 33863167

Following gene: 33863165

Centisome position: 40.44

GC content: 53.96

Gene sequence:

>984_bases
TTGGCCACCCCTCTGGATGGCTTGATGACTGTTTTGCTGCTTGCCCTGCTTGGTTGGGTTGCGACCACAACCCTGCATTG
GCTTTTTGTTGATGCGGATTGGCAAGTCGTTAGCCAAAACCTTCCGCTGTATGCCTTTGGTAGCTATCCACCTCATCAAC
GTTGGCGCCCATTTCTTTGGATTGCGCTGCTGATAGGCCTCACCTTTTTAACGCTGTTAGGGCCACGTCGGGGTTGGATT
CGGAAGGCCTTGCCTTTGGTATGGATTGCGATGGTGCCCTGTGGTGTGGTTCTTCTTGCTGGTGGCCTCGGTTTACTGCC
GATCCCTTCTCATGCATGGGGTGGCCTAACCCTCACCCTGCTGCTAACCGCCTGCAGCGGTGCTCTTGCTCTACCGCTGG
GCATCCTTTTGGCACTCGGGCGTCAAACCAGGCTGGCCGTGATCCAACGAAGTTGCAGCGTCTATATCGACGTGATGCGG
GCTGTTCCTCTAATCGCAGTGTTGTTTTTTGGTCAGCTGTTGATTCCCCTTTTCCTTCCCATGCATCTAGAAGTCAATCG
AGTCCTGCGCGCTGTATTGGCCTTCGCATTATTTGCTGCTGCATACATTGCTGAAGACGTGCGCGGTGGATTGCAAGCGA
TCCCACGAACCCAGCGTGAAGCTGCTGCTGTGCTGGGCCTGAGTCCTAAGCAAATAATTCAACTTGTGGTGTTGCCGCAG
GCACTTCGTACAGCTCTACCGGCCCTGACCAACCAAGCAGTTGGATTGCTTCAGAACACCAGCCTGATGGCCATCTTGGG
TTTGGTGGAACTCCTGGGGATCAGTCGCAGCCTGTTGGCCAACCCTGATTTCATTGGTCGGTATCTGGAGGTGTATGTGT
GGCTAGCAGGGGTTTACTGGTTGGTTTGCACTGCTATGGCCTTACTTGCCCGTCATCTTGAACATCAACTGAGCCCCACA
AGGTCTGCGACTTCAAAGCAATGA

Upstream 100 bases:

>100_bases
GAGAAGTGGTCCGAATTGAGTTTCTAGTTCTCCTGAGTACACCTGCTAAATCCTGATGCAGTCTGGGCCAAGCCCTTTTA
AACGTCTGAAACGGCACCTA

Downstream 100 bases:

>100_bases
TTCCAGCCATTCAAGCCACAGGCCTTGTTAAATCCTTTGGTGATCATCAGCGAGCTCTTGATGAGGTGTCGTTGCATGTT
GAAAGCGGAGAAGTTTTGGT

Product: amino acid ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLWIALLIGLTFLTLLGPRRGWI
RKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRLAVIQRSCSVYIDVMR
AVPLIAVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVLGLSPKQIIQLVVLPQ
ALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYWLVCTAMALLARHLEHQLSPT
RSATSKQ

Sequences:

>Translated_327_residues
MATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLWIALLIGLTFLTLLGPRRGWI
RKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRLAVIQRSCSVYIDVMR
AVPLIAVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVLGLSPKQIIQLVVLPQ
ALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYWLVCTAMALLARHLEHQLSPT
RSATSKQ
>Mature_326_residues
ATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLWIALLIGLTFLTLLGPRRGWIR
KALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRLAVIQRSCSVYIDVMRA
VPLIAVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVLGLSPKQIIQLVVLPQA
LRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYWLVCTAMALLARHLEHQLSPTR
SATSKQ

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=312, Percent_Identity=36.8589743589744, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=32.2115384615385, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=34.2995169082126, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786874, Length=215, Percent_Identity=26.9767441860465, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=29.9019607843137, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI48994930, Length=126, Percent_Identity=31.7460317460317, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787087, Length=210, Percent_Identity=28.0952380952381, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788645, Length=183, Percent_Identity=30.0546448087432, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787086, Length=211, Percent_Identity=28.436018957346, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1788646, Length=168, Percent_Identity=26.7857142857143, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35628; Mature: 35497

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCEEEECCCCCCCCCHHHHH
IALLIGLTFLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
LLTACSGALALPLGILLALGRQTRLAVIQRSCSVYIDVMRAVPLIAVLFFGQLLIPLFLP
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVLGLSPKQIIQLVVLPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
ALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYW
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHH
LVCTAMALLARHLEHQLSPTRSATSKQ
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLW
CCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCEEEECCCCCCCCCHHHHH
IALLIGLTFLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
LLTACSGALALPLGILLALGRQTRLAVIQRSCSVYIDVMRAVPLIAVLFFGQLLIPLFLP
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVLGLSPKQIIQLVVLPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHH
ALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYW
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHH
LVCTAMALLARHLEHQLSPTRSATSKQ
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]