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The map label for this gene is des [H]

Identifier: 33863069

GI number: 33863069

Start: 872385

End: 873470

Strand: Reverse

Name: des [H]

Synonym: PMT0797

Alternate gene names: 33863069

Gene position: 873470-872385 (Counterclockwise)

Preceding gene: 33863070

Following gene: 33863068

Centisome position: 36.23

GC content: 40.7

Gene sequence:

>1086_bases
TTGCAACGCAGTGACCCTTTGGCTTGTTGGCAGTTGTTCTCCACTCTTGTTCCGATCGCTGGATTATGGCTGATGGTGTC
ATTGATTGGGCATGCATCCTCTCCAGTTGGCCTGAAGGCCGTTCAATTTTTTATTGTTCTTGTCCTGTTGGTTTTGCTGT
CGTCTCGTTGCTTTGCTTTAATGCACGATTGCGGACACGGTTCTCTTTTTCACTCCCGATGGCTCAACCGTTCAGCCGGT
TTTTTTCTTGGAGTGCTGAATGCGATACCTCAACACCCTTGGTCACGAGGCCATGCCTATCATCATAAACACAATGGAAA
TTGGCAGCGTTATCGAGGCCCTTCAGCTTTACTAACTCTTGCTCAGTATCAATCTCTATCTAAAATCAACAAGTTTATAT
ATTTTATAAGTCGGCATCCATTGATGTTATTTCCTGGTGGTTTCTTTTACCTCATAATTAAGCCTCGATTGGCCTTAATC
CTGGGATTAATAGAATACTGTTGGTCTAAGTGCCGTCAATTTGTTTTAGGTCTTCGAGATGATGGCTGGAAAAGTATCAA
TATTTTTCGCTCTCAATTACTGAACCATCAGTCAAGTTATTGGTATACCTCTGGAGAATTAGCTGATCTTCTGGCAAATA
ACCTCTTAGTACTAGCAAGTTGGTTTTTAATGAGTCGATGGCTTGGAGTCGGTCTGTTTTGGATCTGTTATTCGTTGGTG
ATGACAGCTTCGGCAGCAATCTTTATTTGCATCTTTTTTGTTCAACATAATTTCGAAGGTTCCTATGCTCATGGTAATAA
CGACTGGAGCTATTTTACTGCTGCACTTGAAGGGAGTAGCAATTTAGATATTCCACTATGGCTTAATTGGTTTTTTGCAG
ATATTTCTTTTCACAGTATTCATCATCTTTGCGAGCGTATCCCTAATTATAGATTGAAGGCATGCCATGCACATAATAAA
GCACTTCTGCATGGAGCAAAGAAATTACGCATTAAAGACATACCAGATTGCTTTGCTTATATTCTTTGGGACTCTGACTC
CAATAAGTTAGTCACACTACAAGAGGCAAATCTACAACCAGTTTGA

Upstream 100 bases:

>100_bases
CACTTCAAACGTTAGCCAGATCCCAACACAATCCTACGATCCACCAATCCCACCAGAGAACAGGCCTCTAAACAGGACTG
ATTTCGTCATTGAGCCCTAC

Downstream 100 bases:

>100_bases
TTAGAGCATCTAAAACGTAGATATTCTATTTGCTTTCACCACAATCAACATAGAATCTGTTTTGAAATCTAATAACCTGC
TGTTACGGTAACTAAAACGG

Product: Fatty acid desaturase, type 2

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MQRSDPLACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQFFIVLVLLVLLSSRCFALMHDCGHGSLFHSRWLNRSAG
FFLGVLNAIPQHPWSRGHAYHHKHNGNWQRYRGPSALLTLAQYQSLSKINKFIYFISRHPLMLFPGGFFYLIIKPRLALI
LGLIEYCWSKCRQFVLGLRDDGWKSINIFRSQLLNHQSSYWYTSGELADLLANNLLVLASWFLMSRWLGVGLFWICYSLV
MTASAAIFICIFFVQHNFEGSYAHGNNDWSYFTAALEGSSNLDIPLWLNWFFADISFHSIHHLCERIPNYRLKACHAHNK
ALLHGAKKLRIKDIPDCFAYILWDSDSNKLVTLQEANLQPV

Sequences:

>Translated_361_residues
MQRSDPLACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQFFIVLVLLVLLSSRCFALMHDCGHGSLFHSRWLNRSAG
FFLGVLNAIPQHPWSRGHAYHHKHNGNWQRYRGPSALLTLAQYQSLSKINKFIYFISRHPLMLFPGGFFYLIIKPRLALI
LGLIEYCWSKCRQFVLGLRDDGWKSINIFRSQLLNHQSSYWYTSGELADLLANNLLVLASWFLMSRWLGVGLFWICYSLV
MTASAAIFICIFFVQHNFEGSYAHGNNDWSYFTAALEGSSNLDIPLWLNWFFADISFHSIHHLCERIPNYRLKACHAHNK
ALLHGAKKLRIKDIPDCFAYILWDSDSNKLVTLQEANLQPV
>Mature_361_residues
MQRSDPLACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQFFIVLVLLVLLSSRCFALMHDCGHGSLFHSRWLNRSAG
FFLGVLNAIPQHPWSRGHAYHHKHNGNWQRYRGPSALLTLAQYQSLSKINKFIYFISRHPLMLFPGGFFYLIIKPRLALI
LGLIEYCWSKCRQFVLGLRDDGWKSINIFRSQLLNHQSSYWYTSGELADLLANNLLVLASWFLMSRWLGVGLFWICYSLV
MTASAAIFICIFFVQHNFEGSYAHGNNDWSYFTAALEGSSNLDIPLWLNWFFADISFHSIHHLCERIPNYRLKACHAHNK
ALLHGAKKLRIKDIPDCFAYILWDSDSNKLVTLQEANLQPV

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 41421; Mature: 41421

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSDPLACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQFFIVLVLLVLLSSRCFAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MHDCGHGSLFHSRWLNRSAGFFLGVLNAIPQHPWSRGHAYHHKHNGNWQRYRGPSALLTL
HHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHH
AQYQSLSKINKFIYFISRHPLMLFPGGFFYLIIKPRLALILGLIEYCWSKCRQFVLGLRD
HHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGWKSINIFRSQLLNHQSSYWYTSGELADLLANNLLVLASWFLMSRWLGVGLFWICYSLV
CCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTASAAIFICIFFVQHNFEGSYAHGNNDWSYFTAALEGSSNLDIPLWLNWFFADISFHSI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
HHLCERIPNYRLKACHAHNKALLHGAKKLRIKDIPDCFAYILWDSDSNKLVTLQEANLQP
HHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHEEEEEEECCCCCEEEEECCCCCC
V
C
>Mature Secondary Structure
MQRSDPLACWQLFSTLVPIAGLWLMVSLIGHASSPVGLKAVQFFIVLVLLVLLSSRCFAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MHDCGHGSLFHSRWLNRSAGFFLGVLNAIPQHPWSRGHAYHHKHNGNWQRYRGPSALLTL
HHHCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHH
AQYQSLSKINKFIYFISRHPLMLFPGGFFYLIIKPRLALILGLIEYCWSKCRQFVLGLRD
HHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGWKSINIFRSQLLNHQSSYWYTSGELADLLANNLLVLASWFLMSRWLGVGLFWICYSLV
CCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTASAAIFICIFFVQHNFEGSYAHGNNDWSYFTAALEGSSNLDIPLWLNWFFADISFHSI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
HHLCERIPNYRLKACHAHNKALLHGAKKLRIKDIPDCFAYILWDSDSNKLVTLQEANLQP
HHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCCHHEEEEEEECCCCCEEEEECCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]