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The map label for this gene is glcK [H]

Identifier: 33862710

GI number: 33862710

Start: 491650

End: 492564

Strand: Reverse

Name: glcK [H]

Synonym: PMT0437

Alternate gene names: 33862710

Gene position: 492564-491650 (Counterclockwise)

Preceding gene: 33862711

Following gene: 33862709

Centisome position: 20.43

GC content: 56.39

Gene sequence:

>915_bases
GTGGCAACCGACTTAGCTCAGTTCATCGGTGTCGATTTGGGAGGTACCGCGATCAAGTTAGGTCGATTTGATCAGCAGGG
CCATCTGTTGGCAGAAACCGAGTTGCCAACCCCTCAACCCTCGGTGCCAGGTGCTGTCACAGTTGCTCTTTGCGAAGCTA
TCGAGACCGTTGATCCAAACCATCATGCTGCATTCGTGGGAGTGGGCTTACCAGGACCAATGGATGCTGAAGGCCGGGTC
GCCAGGGTCTGTATCAACCTGCCTGGATGGCTGGAGGTTCCTTTAGCCGACTGGTTGGAACCACGACTGAATCGGCACGT
TACCCTGGCGAATGATGGCAACTGTGCTCTCGTTGGTGAAGCATGGCAGGGCGCGGCCCAAGATTTTGAAAACGTCGTTC
TGCTCACTCTTGGCACCGGAGTAGGTGGGGGCGTCATGCTTGGTGGTCAATTGTTTGTTGGTCATAACGGAGCTGCAGCC
GAGCCTGGTCTGATTGGGGTGGATTCTGAAGGTCCCAGCTGCAACAGTGGCAACCAAGGCTCCCTAGAGCAGTACGCCAG
CATTGACGCCCTTCAACGTCTATGGGCTGGGGACCCAGAAGAATTAAGCGACCGAGCTGCTTCTGGCGATCGCGAGGCTC
TCGAGATCTGGGAAACCTATGGCCGCAAACTTGGGGTGGGAATCAGTTCTCTCGTCTATGTTTTCACCCCTCAGCTGGTG
CTGGTCGGAGGAGGTCTTGCAGGTGGAGCAGTTCATTTCCTACCAACGGTCCGTCAGGAAGTAGAGAAGCGGGTGCAAGC
TGTGAGCAGAGAGGGTTTGCAGATTCGCTCCTGTGCCCTTGGGAATGGAGCTGGTCGCCTGGGGGCAGCTCGACTTGCCC
TTCAACGTCTCTTAAGTGTCGGCAATGCCCCTTGA

Upstream 100 bases:

>100_bases
CTTACTTATCAAATCAGTCCCAGCATGAATCTCTCAGGCTCTGTAGACAGCCAGGGAATTTGGCAGAGCCAATTGCAATT
ATTTTTCCGCTTTTGACCAG

Downstream 100 bases:

>100_bases
GGCGTAATGATGAGCACAGCTGTGCCGCGCTGTGATGACAACTTCCCCTGGAGTTCCTGAGCCTTCCGCCCAGTTGCTGC
GACTTGCAGCAGAGGTGCGG

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MATDLAQFIGVDLGGTAIKLGRFDQQGHLLAETELPTPQPSVPGAVTVALCEAIETVDPNHHAAFVGVGLPGPMDAEGRV
ARVCINLPGWLEVPLADWLEPRLNRHVTLANDGNCALVGEAWQGAAQDFENVVLLTLGTGVGGGVMLGGQLFVGHNGAAA
EPGLIGVDSEGPSCNSGNQGSLEQYASIDALQRLWAGDPEELSDRAASGDREALEIWETYGRKLGVGISSLVYVFTPQLV
LVGGGLAGGAVHFLPTVRQEVEKRVQAVSREGLQIRSCALGNGAGRLGAARLALQRLLSVGNAP

Sequences:

>Translated_304_residues
MATDLAQFIGVDLGGTAIKLGRFDQQGHLLAETELPTPQPSVPGAVTVALCEAIETVDPNHHAAFVGVGLPGPMDAEGRV
ARVCINLPGWLEVPLADWLEPRLNRHVTLANDGNCALVGEAWQGAAQDFENVVLLTLGTGVGGGVMLGGQLFVGHNGAAA
EPGLIGVDSEGPSCNSGNQGSLEQYASIDALQRLWAGDPEELSDRAASGDREALEIWETYGRKLGVGISSLVYVFTPQLV
LVGGGLAGGAVHFLPTVRQEVEKRVQAVSREGLQIRSCALGNGAGRLGAARLALQRLLSVGNAP
>Mature_303_residues
ATDLAQFIGVDLGGTAIKLGRFDQQGHLLAETELPTPQPSVPGAVTVALCEAIETVDPNHHAAFVGVGLPGPMDAEGRVA
RVCINLPGWLEVPLADWLEPRLNRHVTLANDGNCALVGEAWQGAAQDFENVVLLTLGTGVGGGVMLGGQLFVGHNGAAAE
PGLIGVDSEGPSCNSGNQGSLEQYASIDALQRLWAGDPEELSDRAASGDREALEIWETYGRKLGVGISSLVYVFTPQLVL
VGGGLAGGAVHFLPTVRQEVEKRVQAVSREGLQIRSCALGNGAGRLGAARLALQRLLSVGNAP

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=277, Percent_Identity=29.9638989169675, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI298566315, Length=277, Percent_Identity=29.9638989169675, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4885285, Length=277, Percent_Identity=29.9638989169675, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI190014632, Length=277, Percent_Identity=29.9638989169675, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1787363, Length=309, Percent_Identity=31.0679611650485, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786891, Length=322, Percent_Identity=26.0869565217391, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI87081733, Length=309, Percent_Identity=30.42071197411, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787878, Length=240, Percent_Identity=25.4166666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082230, Length=255, Percent_Identity=30.9803921568627, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790522, Length=296, Percent_Identity=26.6891891891892, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 31544; Mature: 31413

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDLAQFIGVDLGGTAIKLGRFDQQGHLLAETELPTPQPSVPGAVTVALCEAIETVDPN
CCCHHHHHHCCCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
HHAAFVGVGLPGPMDAEGRVARVCINLPGWLEVPLADWLEPRLNRHVTLANDGNCALVGE
CCEEEEEECCCCCCCCCCCEEEEEECCCCCEECCHHHHHHHHHCCEEEEECCCCEEEEEH
AWQGAAQDFENVVLLTLGTGVGGGVMLGGQLFVGHNGAAAEPGLIGVDSEGPSCNSGNQG
HHCCHHHHHCCEEEEEECCCCCCCEEECCEEEEECCCCCCCCCEEEECCCCCCCCCCCCC
SLEQYASIDALQRLWAGDPEELSDRAASGDREALEIWETYGRKLGVGISSLVYVFTPQLV
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCHHHCCCHHHHHHHHCCCEE
LVGGGLAGGAVHFLPTVRQEVEKRVQAVSREGLQIRSCALGNGAGRLGAARLALQRLLSV
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
GNAP
CCCC
>Mature Secondary Structure 
ATDLAQFIGVDLGGTAIKLGRFDQQGHLLAETELPTPQPSVPGAVTVALCEAIETVDPN
CCHHHHHHCCCCCCCEEEECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
HHAAFVGVGLPGPMDAEGRVARVCINLPGWLEVPLADWLEPRLNRHVTLANDGNCALVGE
CCEEEEEECCCCCCCCCCCEEEEEECCCCCEECCHHHHHHHHHCCEEEEECCCCEEEEEH
AWQGAAQDFENVVLLTLGTGVGGGVMLGGQLFVGHNGAAAEPGLIGVDSEGPSCNSGNQG
HHCCHHHHHCCEEEEEECCCCCCCEEECCEEEEECCCCCCCCCEEEECCCCCCCCCCCCC
SLEQYASIDALQRLWAGDPEELSDRAASGDREALEIWETYGRKLGVGISSLVYVFTPQLV
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHCHHHCCCHHHHHHHHCCCEE
LVGGGLAGGAVHFLPTVRQEVEKRVQAVSREGLQIRSCALGNGAGRLGAARLALQRLLSV
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
GNAP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]